[go: up one dir, main page]

WO1995016435A3 - Improved intraocular irrigating solution containing non-steroidal antiinflammatory agent - Google Patents

Improved intraocular irrigating solution containing non-steroidal antiinflammatory agent Download PDF

Info

Publication number
WO1995016435A3
WO1995016435A3 PCT/US1994/014196 US9414196W WO9516435A3 WO 1995016435 A3 WO1995016435 A3 WO 1995016435A3 US 9414196 W US9414196 W US 9414196W WO 9516435 A3 WO9516435 A3 WO 9516435A3
Authority
WO
WIPO (PCT)
Prior art keywords
solution containing
steroidal antiinflammatory
containing non
antiinflammatory agent
irrigating solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1994/014196
Other languages
French (fr)
Other versions
WO1995016435A2 (en
Inventor
Gerald D Cagle
Ole J Lorenzetti
Owen Gan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Vision LLC
Original Assignee
Alcon Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Laboratories Inc filed Critical Alcon Laboratories Inc
Priority to AU13996/95A priority Critical patent/AU1399695A/en
Priority to EP95905340A priority patent/EP0734248A1/en
Priority to JP7516860A priority patent/JPH09506620A/en
Publication of WO1995016435A2 publication Critical patent/WO1995016435A2/en
Publication of WO1995016435A3 publication Critical patent/WO1995016435A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Pharmaceutical compositions useful in ophthalmic surgery are described. The compositions include one or more non-steroidal antiinflammatory drugs, and are useful for preventing or treating ophthalmic inflammation and other conditions associated with ophthalmic surgery. Methods of using the compositions in connection with ophthalmic surgical procedures are also described.
PCT/US1994/014196 1993-12-17 1994-12-13 Improved intraocular irrigating solution containing non-steroidal antiinflammatory agent Ceased WO1995016435A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU13996/95A AU1399695A (en) 1993-12-17 1994-12-13 Improved intraocular irrigating solution containing non-steroidal antiinflammatory agent
EP95905340A EP0734248A1 (en) 1993-12-17 1994-12-13 Improved intraocular irrigating solution containing non-steroidal antiinflammatory agent
JP7516860A JPH09506620A (en) 1993-12-17 1994-12-13 Improved intraocular irrigation solution containing non-steroidal anti-inflammatory agents

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16946893A 1993-12-17 1993-12-17
US08/169,468 1993-12-17

Publications (2)

Publication Number Publication Date
WO1995016435A2 WO1995016435A2 (en) 1995-06-22
WO1995016435A3 true WO1995016435A3 (en) 1995-07-06

Family

ID=22615834

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1994/014196 Ceased WO1995016435A2 (en) 1993-12-17 1994-12-13 Improved intraocular irrigating solution containing non-steroidal antiinflammatory agent

Country Status (5)

Country Link
EP (1) EP0734248A1 (en)
JP (1) JPH09506620A (en)
AU (1) AU1399695A (en)
CA (1) CA2179147A1 (en)
WO (1) WO1995016435A2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7091181B2 (en) 1994-12-12 2006-08-15 Omeros Corporation Method of inhibition of pain and inflammation during surgery comprising administration of soluble TNF receptors
MX9703988A (en) * 1994-12-12 1998-02-28 Omeros Med Sys Inc SOLUTION AND IRRIGATION METHOD FOR THE INHIBITION OF PAIN, INFLAMMATION AND IT IS SPASM.
AU4467396A (en) 1994-12-12 1996-07-10 Omeros Medical Systems, Inc. Irrigation solution and method for inhibition of pain, inflammation and spasm
US6492332B1 (en) 1995-12-12 2002-12-10 Omeros Corporation Irrigation solution and methods for inhibition of tumor cell adhesion, pain and inflammation
US6413961B1 (en) 1995-12-12 2002-07-02 Omeros Medical Systems, Inc. Irrigation solution and method for inhibition of pain and inflammation
RU2115413C1 (en) * 1997-03-03 1998-07-20 Малое государственное предприятие "Научно-экспериментальное производство" Irrigation solution "intrasol"
DK1534313T3 (en) 2002-07-30 2013-02-04 Omeros Corp Ophthalmological irrigation solutions and method
AU2013201465B2 (en) 2012-10-24 2016-03-03 Rayner Intraocular Lenses Limited Stable preservative-free mydriatic and anti-inflammatory solutions for injection
TWI705812B (en) 2014-12-01 2020-10-01 奥默羅斯公司 Anti-inflammatory and mydriatic intracameral solutions for inhibition of postoperative ocular inflammatory conditions
CN111494307A (en) * 2019-01-30 2020-08-07 北京普德康利医药科技发展有限公司 A kind of flurbiprofen injection
US12029729B2 (en) 2021-07-23 2024-07-09 Somerset Therapeutics, Llc Chelated, stable ophthalmological compositions of ketorolac and phenylephrine and applications thereof
US20230039551A1 (en) 2021-07-23 2023-02-09 Somerset Therapeutics, Llc Buffer- and chelator-free, stable ophthalmological compositions of ketorolac and phenylephrine and applications thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0076658A2 (en) * 1981-10-05 1983-04-13 Alcon Laboratories, Inc. Ophthalmic irrigating solution
US4550022A (en) * 1981-10-05 1985-10-29 Alcon Laboratories, Inc. Tissue irrigating solution
EP0306984A1 (en) * 1987-09-11 1989-03-15 Syntex (U.S.A.) Inc. Preservative system for ophtalmic formulations
EP0364266A2 (en) * 1988-10-12 1990-04-18 Eye Research Institute Of Retina Foundation Inc NSAID and/or EGF for enhancing the healing of corneal endothelial wounds
US5051443A (en) * 1988-10-12 1991-09-24 Eye Research Institute Of Retina Foundation, Inc. Method for enhancing healing of corneal endothelial wounds

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0076658A2 (en) * 1981-10-05 1983-04-13 Alcon Laboratories, Inc. Ophthalmic irrigating solution
US4550022A (en) * 1981-10-05 1985-10-29 Alcon Laboratories, Inc. Tissue irrigating solution
EP0306984A1 (en) * 1987-09-11 1989-03-15 Syntex (U.S.A.) Inc. Preservative system for ophtalmic formulations
EP0364266A2 (en) * 1988-10-12 1990-04-18 Eye Research Institute Of Retina Foundation Inc NSAID and/or EGF for enhancing the healing of corneal endothelial wounds
US5051443A (en) * 1988-10-12 1991-09-24 Eye Research Institute Of Retina Foundation, Inc. Method for enhancing healing of corneal endothelial wounds

Also Published As

Publication number Publication date
JPH09506620A (en) 1997-06-30
EP0734248A1 (en) 1996-10-02
WO1995016435A2 (en) 1995-06-22
CA2179147A1 (en) 1995-06-22
AU1399695A (en) 1995-07-03

Similar Documents

Publication Publication Date Title
CA2030459A1 (en) Biodegradable ocular implants
CA2257976A1 (en) Compositions and methods for coating medical devices
AU5056196A (en) Hydrogel-forming, self-solvating absorbable polyester copolymers and methods for use thereof
TR199801180T2 (en) New compounds with analgesic effect.
WO1995016435A3 (en) Improved intraocular irrigating solution containing non-steroidal antiinflammatory agent
CA2294921A1 (en) Levobupivacaine and its use
NO954878L (en) pyrrole
WO1998039293A3 (en) 13-thia prostaglandins for use in glaucoma therapy
CA2340320A1 (en) Use of an angiogenic factor for the treatment of microascular angiopathies
WO2000018316A3 (en) Sustained release, and comfortable ophthalmic composition and method for ocular therapy
NO994165L (en) Use of descarboethoxyloratadine for the manufacture of a medicament for the treatment of urinary incontinence, travel sickness and dizziness
HK1047707A1 (en) Use of (+)-tramadol, o-demethyltramadol or (+)-o-demethyltramadol, o-desmethyl-n-mono-desmethyl-tramadol or (+)-o-desmethyl-n-mono-desmethyl-tramadol for treating urinary incontinence
AU6391000A (en) Method of preventing the injury or death of retinal cells and treating ocular diseases
WO1996040743A3 (en) Inhibitors of factor xa
AU3382089A (en) Uncrosslinked hydrogel, process for its preparation and its uses as an article for medical and/or surgical purposes such as tubes, filaments, films, joints, implants and the like, particularly in ophthalmology
NO984572L (en) Use of 2,5-dihydroxybenzenesulfone derivatives for the manufacture of drugs intended for normalization of endothelial function, for the treatment of sexual dysfunction and vascular complications in diabetes, as well as vascular disorders of
EP1065200A4 (en) Aminoisoquinoline derivatives
AU3401093A (en) Therapeutic agent for threatened abortion
TR199801184T2 (en) New compounds with analgesic action.
CA2369275A1 (en) Process for the preparation of autocrosslinked compounds of hyaluronic acid and the derivatives thereof by the supercritical antisolvent technique
DE69739190D1 (en) MEDICAMENT FOR THE TREATMENT OF OCULAR CRUSH DISEASES
DE69100171D1 (en) SYNERGISTIC COMBINATION FOR OPHTHALMIC USE.
ATE204169T1 (en) INTRAOCULAR IRRIGATION SOLUTION CONTAINING POLYAMINE ANTAGONISTS
AU5903690A (en) Use in therapy of 10-amino-5,6-dihydro-11h-dibenzo(b,e) azepine-6, 11-dione and derivatives as drugs for use in the treatment of urinary incontinence
IE873231L (en) Medicaments

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AU CA JP

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE

AK Designated states

Kind code of ref document: A3

Designated state(s): AU CA JP

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 1995905340

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2179147

Country of ref document: CA

WWP Wipo information: published in national office

Ref document number: 1995905340

Country of ref document: EP

WWW Wipo information: withdrawn in national office

Ref document number: 1995905340

Country of ref document: EP