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WO1995012682A3 - Viral vector with bovine viral diarrhea virus (bvdv) antigens - Google Patents

Viral vector with bovine viral diarrhea virus (bvdv) antigens Download PDF

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Publication number
WO1995012682A3
WO1995012682A3 PCT/US1994/012198 US9412198W WO9512682A3 WO 1995012682 A3 WO1995012682 A3 WO 1995012682A3 US 9412198 W US9412198 W US 9412198W WO 9512682 A3 WO9512682 A3 WO 9512682A3
Authority
WO
WIPO (PCT)
Prior art keywords
bvdv
antigens
diarrhea virus
virus
bovine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1994/012198
Other languages
French (fr)
Other versions
WO1995012682A2 (en
Inventor
Elizabeth J Haanes
Richard C Wardley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Priority to EP95901037A priority Critical patent/EP0725831A1/en
Priority to NZ276234A priority patent/NZ276234A/en
Priority to JP7513263A priority patent/JPH09504435A/en
Priority to AU10423/95A priority patent/AU688819B2/en
Priority to KR1019960702343A priority patent/KR960705944A/en
Publication of WO1995012682A2 publication Critical patent/WO1995012682A2/en
Publication of WO1995012682A3 publication Critical patent/WO1995012682A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16641—Use of virus, viral particle or viral elements as a vector
    • C12N2710/16643—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

This invention relates to the field of Bovine Viral Diarrhea Virus (BVDV), and vaccines for the treatment thereof. This invention describes the preparation of live, attenuated Bovine Herpesvirus type 1 (BHV-1) as a virus, vaccine and vector for expression of BVDV antigens. A BVDV cDNA clone containing sequences corresponding to glycoprotein gp53 is inserted into an inactivated BHV-1 virus.
PCT/US1994/012198 1993-11-05 1994-10-31 Viral vector with bovine viral diarrhea virus (bvdv) antigens Ceased WO1995012682A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP95901037A EP0725831A1 (en) 1993-11-05 1994-10-31 Viral vector with bovine viral diarrhea virus (bvdv) antigens
NZ276234A NZ276234A (en) 1993-11-05 1994-10-31 An attenuated replicating non pathogenic flavivirus (bovine viral diarrhoea virus - bvdv) vaccine
JP7513263A JPH09504435A (en) 1993-11-05 1994-10-31 Viral vector with bovine viral diarrhea virus (BVDV) antigen
AU10423/95A AU688819B2 (en) 1993-11-05 1994-10-31 Viral vector with bovine viral diarrhea virus (BVDV) antigens
KR1019960702343A KR960705944A (en) 1993-11-05 1994-10-31 Viral VECTOR WITH BOVINE VIRAL DIARRHEA VIRUS (BVDV) ANTIGENS

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14781093A 1993-11-05 1993-11-05
US08/147,810 1993-11-05

Publications (2)

Publication Number Publication Date
WO1995012682A2 WO1995012682A2 (en) 1995-05-11
WO1995012682A3 true WO1995012682A3 (en) 1995-07-06

Family

ID=22522990

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1994/012198 Ceased WO1995012682A2 (en) 1993-11-05 1994-10-31 Viral vector with bovine viral diarrhea virus (bvdv) antigens

Country Status (9)

Country Link
EP (1) EP0725831A1 (en)
JP (1) JPH09504435A (en)
KR (1) KR960705944A (en)
CN (1) CN1134175A (en)
AU (1) AU688819B2 (en)
CA (1) CA2172815A1 (en)
MX (1) MXPA94008605A (en)
NZ (1) NZ276234A (en)
WO (1) WO1995012682A2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6060457A (en) * 1996-06-20 2000-05-09 Universite De Montreal DNA plasmid vaccine for immunization of animals against BVDV
RU2158306C2 (en) * 1999-01-19 2000-10-27 Институт экспериментальной ветеринарии Сибири и Дальнего Востока СО РАСХН Method of detection of cattle viral diarrhea virus (mucosa disease) using specific oligonucleotide primers in polymerase chain reaction
EP1026252A1 (en) * 1999-02-02 2000-08-09 Akzo Nobel N.V. Synthetic gene of bovine viral diarrhoea virus
EP1104676A1 (en) 1999-11-30 2001-06-06 Boehringer Ingelheim Vetmedica Gmbh Safe attenuated bovine viral diarrhea viruses for use in pregnant cows
KR100331176B1 (en) * 1999-12-15 2002-04-06 대한민국(관리청:특허청장, 승계청:국립수의과학검역원장) A diagnostic method of bovine viral diarrhea using recombination protein as an antigen
EP2365082A1 (en) * 2000-06-27 2011-09-14 Pfizer Animal Health S.A. BVDV virus-like particles
EA011578B1 (en) 2002-08-26 2009-04-28 Пфайзер Продактс Инк. Immunogenic composition for preventing cattle from infections of respiratory and reproductive systems and use thereof
EP1708742A4 (en) * 2003-12-05 2008-11-05 Becton Dickinson Co Methods of enhancing immune response in the intradermal compartment and compounds useful thereof
KR101876535B1 (en) * 2012-06-14 2018-07-09 베트올 (주) Antibody for detecting of bovine viral diarrhea virus(bvdv), bvdv antigen detecting method and test kit using thereof
EP2983703A1 (en) 2013-03-15 2016-02-17 Zoetis Services LLC Cross-protection of bovines against b. trehalosi infection by a multi-valent vaccine
CN113913461A (en) * 2021-11-15 2022-01-11 贵州大学 Construction of E0-E2 Gene Recombinant Adenovirus Vaccine for Bovine Viral Diarrhea
KR20250103818A (en) * 2023-12-27 2025-07-08 주식회사 보레다바이오텍 Bovine diarrhea-causing virus -diagnosis kit

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0119025A2 (en) * 1983-02-25 1984-09-19 Baylor College of Medicine Thymidine kinase-negative temperature resistant bovine herpesvirus-1 mutant as a vaccine against infectious bovine rhinotracheitis
WO1990001337A1 (en) * 1988-08-03 1990-02-22 Institute For Animal Health Limited Vaccine
EP0464010A1 (en) * 1990-06-08 1992-01-02 Statens Veterinärmedicinska Anstalt A method of detecting an infection caused by a specific type of virus, primers, probes and a test kit
WO1994000586A2 (en) * 1992-06-26 1994-01-06 Rhône Merieux Infectious bovine rhinotracheitis virus mutants and vaccines

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0119025A2 (en) * 1983-02-25 1984-09-19 Baylor College of Medicine Thymidine kinase-negative temperature resistant bovine herpesvirus-1 mutant as a vaccine against infectious bovine rhinotracheitis
WO1990001337A1 (en) * 1988-08-03 1990-02-22 Institute For Animal Health Limited Vaccine
EP0464010A1 (en) * 1990-06-08 1992-01-02 Statens Veterinärmedicinska Anstalt A method of detecting an infection caused by a specific type of virus, primers, probes and a test kit
WO1994000586A2 (en) * 1992-06-26 1994-01-06 Rhône Merieux Infectious bovine rhinotracheitis virus mutants and vaccines

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BELLO, L. ET AL.: "Bovine herpesvirus 1 as a live virus vector for expression of foreign genes", VIROLOGY, vol. 190, no. 2, 1992, pages 666 - 673 *
PATON, D.J. ET AL.: "Epitope mapping of the gp53 envelope protein of bovine viral diarrhea virus", VIROLOGY, vol. 190, no. 2, 1992, pages 763 - 772 *
YU, M. ET AL.: "High level expression of the envelope glycoprotein (GP53) of bovine viral diarrhoea virus (singer) and its potential use as diagnostic reagent", VIRUS RESEARCH, vol. 34, no. 2, 1994, pages 178 - 186 *

Also Published As

Publication number Publication date
KR960705944A (en) 1996-11-08
JPH09504435A (en) 1997-05-06
AU688819B2 (en) 1998-03-19
AU1042395A (en) 1995-05-23
MXPA94008605A (en) 2004-11-11
EP0725831A1 (en) 1996-08-14
NZ276234A (en) 1998-01-26
CN1134175A (en) 1996-10-23
CA2172815A1 (en) 1995-05-11
WO1995012682A2 (en) 1995-05-11

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