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WO1994028129A3 - Tumour metastasis gene - Google Patents

Tumour metastasis gene Download PDF

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Publication number
WO1994028129A3
WO1994028129A3 PCT/GB1994/001160 GB9401160W WO9428129A3 WO 1994028129 A3 WO1994028129 A3 WO 1994028129A3 GB 9401160 W GB9401160 W GB 9401160W WO 9428129 A3 WO9428129 A3 WO 9428129A3
Authority
WO
WIPO (PCT)
Prior art keywords
tumour metastasis
metastasis gene
dna fragment
gene
tumour
Prior art date
Application number
PCT/GB1994/001160
Other languages
French (fr)
Other versions
WO1994028129A2 (en
Inventor
David Tarin
Original Assignee
Isis Innovation
David Tarin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isis Innovation, David Tarin filed Critical Isis Innovation
Priority to CA002149633A priority Critical patent/CA2149633A1/en
Priority to JP7500405A priority patent/JPH09504682A/en
Priority to AU68022/94A priority patent/AU6802294A/en
Priority to EP94916320A priority patent/EP0700436A1/en
Publication of WO1994028129A2 publication Critical patent/WO1994028129A2/en
Publication of WO1994028129A3 publication Critical patent/WO1994028129A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)

Abstract

A 2858bp DNA fragment (SEQ ID NO:1) is provided which codes for a protein which is expressed in malignant human tumours and their metastases. The DNA fragment is useful in diagnosing or assessing the prognosis of metastasis of a patient.
PCT/GB1994/001160 1993-05-28 1994-05-27 Tumour metastasis gene WO1994028129A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002149633A CA2149633A1 (en) 1993-05-28 1994-05-27 Tumour metastasis gene
JP7500405A JPH09504682A (en) 1993-05-28 1994-05-27 Tumor metastasis gene
AU68022/94A AU6802294A (en) 1993-05-28 1994-05-27 Tumour metastasis gene
EP94916320A EP0700436A1 (en) 1993-05-28 1994-05-27 Tumour metastasis gene

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9311130.0 1993-05-28
GB939311130A GB9311130D0 (en) 1993-05-28 1993-05-28 Tumor metastasis gene

Publications (2)

Publication Number Publication Date
WO1994028129A2 WO1994028129A2 (en) 1994-12-08
WO1994028129A3 true WO1994028129A3 (en) 1995-02-02

Family

ID=10736338

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1994/001160 WO1994028129A2 (en) 1993-05-28 1994-05-27 Tumour metastasis gene

Country Status (6)

Country Link
EP (1) EP0700436A1 (en)
JP (1) JPH09504682A (en)
AU (1) AU6802294A (en)
CA (1) CA2149633A1 (en)
GB (1) GB9311130D0 (en)
WO (1) WO1994028129A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5783182A (en) * 1996-01-30 1998-07-21 Baylor College Of Medicine Method for identifying metastatic sequences
USRE38490E1 (en) 1995-11-16 2004-04-06 Baylor College Of Medicine Method for identifying metastatic sequences
AU725186B2 (en) * 1995-11-16 2000-10-05 Baylor College Of Medicine Method for identifying metastatic sequences
JP2000504212A (en) * 1996-01-10 2000-04-11 ザ・ユニバーシティ・オブ・リバプール Metastasis-inducing DNA
USRE38392E1 (en) 1996-01-30 2004-01-20 Baylor College Of Medicine Method for identifying metastatic sequences
WO1999022773A2 (en) 1997-11-05 1999-05-14 Baylor College Of Medicine Sequences for targeting metastatic cells
WO1999046385A2 (en) 1998-03-13 1999-09-16 Baylor College Of Medicine Compositions and methods for the treatment and prevention of metastatic disorders
US7462491B2 (en) 2002-01-31 2008-12-09 Baylor College Of Medicine Methods and compositions for diagnosis and monitoring of prostate cancer progression by detection of serum caveolin

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5049662A (en) * 1987-10-13 1991-09-17 The United States Of America As Represented By The Department Of Health And Human Services Kit for diagnosing cancer metastatic potential
WO1992000757A1 (en) * 1990-07-09 1992-01-23 Research Corporation Technologies, Inc. Diagnosis of metastatic cancer by the mts-1 gene

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4064113A (en) * 1973-06-15 1977-12-20 Alelio Gaetano F D Aminophthalic anhydride copolymers
US4131730A (en) * 1975-05-12 1978-12-26 Alelio Gaetano F D Modified polyamic acid from aminophthalic acid anhydride and dianhydride
JPS61143435A (en) * 1984-12-15 1986-07-01 Nitto Electric Ind Co Ltd moisture resistant polyimide
JPS6213436A (en) * 1985-07-11 1987-01-22 Nitto Electric Ind Co Ltd Colorless transparent polyimide molding
JPS61226732A (en) * 1985-03-30 1986-10-08 Nitto Electric Ind Co Ltd Liquid crystal display element
KR930005151B1 (en) * 1990-05-15 1993-06-16 재단법인 한국화학연구소 Polyetherimide Imide Resin and Manufacturing Method Thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5049662A (en) * 1987-10-13 1991-09-17 The United States Of America As Represented By The Department Of Health And Human Services Kit for diagnosing cancer metastatic potential
WO1992000757A1 (en) * 1990-07-09 1992-01-23 Research Corporation Technologies, Inc. Diagnosis of metastatic cancer by the mts-1 gene

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
D. TARIN: "Molecular Genetics of Metastasis", CIBA FOUND. SYMP. ON METASTASIS, vol. 141, 1988, pages 149 - 169 *
J. S. WALLACE ET AL.: "The ras Oncogene and tumor metastasis", DIFFERENTIATION, vol. 41, no. 3, September 1989 (1989-09-01), GERMANY, pages 208 - 215 *
M. CAIRNEY ET AL.: "Secondary Transfer of metastatic capability and confirmation by PCR of concomitant transfer of donor DNA", BRITISH JOURNAL OF CANCER, vol. 62, no. 3, September 1990 (1990-09-01), pages 544 *

Also Published As

Publication number Publication date
AU6802294A (en) 1994-12-20
EP0700436A1 (en) 1996-03-13
CA2149633A1 (en) 1994-12-08
JPH09504682A (en) 1997-05-13
WO1994028129A2 (en) 1994-12-08
GB9311130D0 (en) 1993-07-14

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