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WO1994005267A3 - Use of carrageenans as growth factor antagonists - Google Patents

Use of carrageenans as growth factor antagonists Download PDF

Info

Publication number
WO1994005267A3
WO1994005267A3 PCT/GB1993/001848 GB9301848W WO9405267A3 WO 1994005267 A3 WO1994005267 A3 WO 1994005267A3 GB 9301848 W GB9301848 W GB 9301848W WO 9405267 A3 WO9405267 A3 WO 9405267A3
Authority
WO
WIPO (PCT)
Prior art keywords
growth factor
carrageenans
factor antagonists
useful
disclosed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB1993/001848
Other languages
French (fr)
Other versions
WO1994005267A2 (en
Inventor
Richard Michael Hoffman
Dietrich Herbert Walter Paper
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medical Research Council
Original Assignee
Medical Research Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medical Research Council filed Critical Medical Research Council
Priority to AU49726/93A priority Critical patent/AU4972693A/en
Publication of WO1994005267A2 publication Critical patent/WO1994005267A2/en
Publication of WO1994005267A3 publication Critical patent/WO1994005267A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Disclosed is a substance, being a carrageenan or a derivative thereof, for use as growth factor suppressor or inhibitor. The substances disclosed as being useful as growth factor inhibitors are useful in the treatment of tumours and other conditions where growth factors are involved.
PCT/GB1993/001848 1992-09-01 1993-09-01 Use of carrageenans as growth factor antagonists Ceased WO1994005267A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU49726/93A AU4972693A (en) 1992-09-01 1993-09-01 Use of carrageenans as growth factor antagonists

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929218510A GB9218510D0 (en) 1992-09-01 1992-09-01 Improvements in or relating to hormone antagonists
GB9218510.7 1992-09-01

Publications (2)

Publication Number Publication Date
WO1994005267A2 WO1994005267A2 (en) 1994-03-17
WO1994005267A3 true WO1994005267A3 (en) 1994-04-28

Family

ID=10721240

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1993/001848 Ceased WO1994005267A2 (en) 1992-09-01 1993-09-01 Use of carrageenans as growth factor antagonists

Country Status (3)

Country Link
AU (1) AU4972693A (en)
GB (1) GB9218510D0 (en)
WO (1) WO1994005267A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5968551A (en) 1991-12-24 1999-10-19 Purdue Pharma L.P. Orally administrable opioid formulations having extended duration of effect
FR2808687B1 (en) * 2000-04-27 2003-12-05 Goemar Lab Sa MEDICAMENT CONTAINING POLYSACCHARIDE SUBSTANCES FOR THE ACTIVATION OF APOPTOSIS

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988006396A2 (en) * 1987-02-25 1988-09-07 Michael Neushul Method for the treatment of aids virus and other retroviruses

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988006396A2 (en) * 1987-02-25 1988-09-07 Michael Neushul Method for the treatment of aids virus and other retroviruses

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 89, no. 3, 17 July 1978, Columbus, Ohio, US; abstract no. 22078w, R.G.P. PUGH-HUMPHREYS ET AL: "The effect of the macrophage cytotoxic agent iota-carrageenan on the growth of two transplantable murine ascites tumors." *
CHEMICAL ABSTRACTS, vol. 95, no. 9, 31 August 1981, Columbus, Ohio, US; abstract no. 73721g, E. OHTSUKA: "Activation of cytotoxic macrophages by carrageenan with special reference to iota- carrageenan." *
D.R. COOMBE ET AL.: "Analysis of the inhibition of tumour metastasis by sulphated polysaccharides.", INT. J. CANCER, vol. 39, no. 1, 1987, pages 82 - 88 *
H. NODA ET AL: "Antitumor activity of marine algae.", HYDROBIOLOGIA, vol. 204/205, 1990, pages 577 - 584 *
KEITH, MCBRIDE, STUART, EDS., PROC. EURES SYMP. MACROPHAGE CANCER, 1977, pages 142 - 154 *
NICHIDAI IGAKU ZASSHI, vol. 40, no. 6, 1981, pages 521 - 528 *
R. ISHAI-MICHAELI ET AL: "heparanase activity expressed by platelets, neutrophils and lymphoma cells releases active fibroblast growth factor from extracellular matrix.", CELL REGUL., vol. 1, no. 11, 1990, pages 833 - 842 *
T. MATSUMOTO ET AL.: "Growth inhibition of leukemia L-1210 ascites tumor by combination of carrageenan and mitomycin C in vivo.", J. PHARMACO-BIODYN., vol. 7, no. 7, 1984, pages 465 - 471 *

Also Published As

Publication number Publication date
WO1994005267A2 (en) 1994-03-17
AU4972693A (en) 1994-03-29
GB9218510D0 (en) 1992-10-14

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WO1994005267A3 (en) Use of carrageenans as growth factor antagonists

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