[go: up one dir, main page]

WO1994000016A1 - Inactivation biochimique de virus a arn - Google Patents

Inactivation biochimique de virus a arn Download PDF

Info

Publication number
WO1994000016A1
WO1994000016A1 PCT/CH1992/000249 CH9200249W WO9400016A1 WO 1994000016 A1 WO1994000016 A1 WO 1994000016A1 CH 9200249 W CH9200249 W CH 9200249W WO 9400016 A1 WO9400016 A1 WO 9400016A1
Authority
WO
WIPO (PCT)
Prior art keywords
rna viruses
rnases
agents
rna
detergents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CH1992/000249
Other languages
German (de)
English (en)
Inventor
Urs V. Wirth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to AU32526/93A priority Critical patent/AU3252693A/en
Publication of WO1994000016A1 publication Critical patent/WO1994000016A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38636—Preparations containing enzymes, e.g. protease or amylase containing enzymes other than protease, amylase, lipase, cellulase, oxidase or reductase
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/50—Isolated enzymes; Isolated proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005—Antimicrobial preparations
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions

Definitions

  • RNases Ribonucleases
  • alRVh anti-infectives against RNA viruses
  • Agents with RNases can be combined with a wide variety of conventional substances (theoretically in all conceivable physical states and mixture types) for cleaning, disinfection or personal care or used as new optimized reagents in various combinations with new formulations.
  • Agents with RNases are suitable for disinfecting objects, such as equipment and clothing, from contaminating RNA viruses.
  • Agents with RNases applied to objects and especially to the skin surfaces, including mucous membranes, are suitable for protecting humans and / or animals from pathogenic RNA viruses.
  • Agents with RNases can also be used to control RNA viruses in crop protection.
  • RNA viruses The use of agents with RNases, combined with other substance mixtures as needed, therefore serves to prevent (prevent) diseases caused by RNA viruses.
  • This role can be described as anti-infectives against RNA viruses (aiRVi). This is independent of disease-treating (therapeutic) measures that are only used after infestation by pathogens.
  • Poliomyelitis viruses e.g. poliomyelitis
  • Coxsackieviruses e.g. meningitis
  • Rhinoviruses e.g. Colds and Colds - Encephalomyocarditis Virus:
  • - Arboviruses e.g. Encephalitis or encephalomyelitis
  • Ortho-M . e.g. Influe ⁇ zaviruses - Para-M .: e.g. Parainflue ⁇ za, Mumps, ...
  • Myxo-like viruses e.g. measles, rubella, distemper, rinderpest, swine fever, ...
  • Retroviruses RNA tumor viruses, ...
  • RSV e.g. Chicken sarcoma, poultry leukosis, MMLV: mouse leukemia, MMTV: mouse
  • Lentiviruses e.g. Visna (animals); HTLV (people); ...
  • RNA viruses also trigger undesirable damage in plants: (Source: F. Schönbeck, plant diseases, Teubner, 1979)
  • RNA viruses with RNases and detergents, possibly with additives for stabilizing and / or enhancing their activity / stability and possibly in combination with conventional substance mixtures.
  • RNA viruses anti-infectious gene RNA viruses
  • Agents with RNases can be combined with a wide variety of conventional substances for cleaning, disinfection or personal care or used as new optimized reagents in various combinations with new formulations:
  • At least one RNase e.g. RNaseA
  • a detergent e.g. Sodium Lauryl Sulfate
  • agents with RNases in all personal care products are suitable, such as: washing lotions, creams, hair shampoos, shower gels, powders, mouthwash, eye drops, intimate care products, ... etc.
  • these agents have a short-term inactivating effect on RNA viruses (disinfectant) or impart a longer-lasting inactivation ability against RNA viruses (long-lasting protective layer).
  • RNA viruses infectious agents
  • long-lasting protective layer the use of agents that leave a relatively resistant film (“protective film”) on the treated surfaces (devices, clothes, etc.) is recommended.
  • Such agents, based on gels, oils or waxes have already been patented in some cases and are used in practice.
  • aiRVi anti-infectives against JRNA viruses based on RNase (s) and suitable detergents
  • RNA-degrading enzymes ribonucleases (RNA-degrading enzymes)
  • RNase A EC 3.1.27.5 .: isolated from bovine pancreas; with the properties described above, available from Sigma (No L5125)
  • RNase T1 EC 3.1.27.3: isolated from Aspergillus oryzam
  • SLS Sodium lauryl sulphate

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Environmental Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dentistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Agronomy & Crop Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Detergent Compositions (AREA)
  • Cosmetics (AREA)

Abstract

Les ribonucléases (RNases) sont des enzymes très actives, d'utilisation aisée et extrêmement stables. En coopération avec des détergents déterminés, les Rnases inactivent et détruisent de manière irréversible les virus à ARN. Des agents contenant des Rnases et des détergents sont par conséquent utiles pour désinfecter des appareils, des vêtements et des surfaces, éliminant les virus à ARN qui les contaminent. Des formes spéciales d'application pour enduire la surface de la peau d'êtres humains, d'animaux ou de plantes réduisent le risque d'infection avec des virus ARN. On pourrait qualifier des agents contenant des Rnases et des détergents, éventuellement associés à d'autres substances, d''agents anti-infectieux protégeant contre des virus à ARN' (ou aiRVI).
PCT/CH1992/000249 1992-06-23 1992-12-31 Inactivation biochimique de virus a arn Ceased WO1994000016A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU32526/93A AU3252693A (en) 1992-06-23 1992-12-31 Biochemical deactivation of RNA viruses

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1957/92-3 1992-06-23
CH1957/92A CH682541A5 (de) 1992-06-23 1992-06-23 Biochemische Inaktivierung von RNA-Viren.

Publications (1)

Publication Number Publication Date
WO1994000016A1 true WO1994000016A1 (fr) 1994-01-06

Family

ID=4222554

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CH1992/000249 Ceased WO1994000016A1 (fr) 1992-06-23 1992-12-31 Inactivation biochimique de virus a arn

Country Status (4)

Country Link
AU (1) AU3252693A (fr)
CA (1) CA2116661A1 (fr)
CH (1) CH682541A5 (fr)
WO (1) WO1994000016A1 (fr)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6017046A (en) * 1998-01-21 2000-01-25 Markovic; Vladimir Wheelchair apparatus
KR100454594B1 (ko) * 2002-07-22 2004-11-03 배흥규 라이스 커틀릿 및 그 제조방법
US9969885B2 (en) 2014-07-31 2018-05-15 Kimberly-Clark Worldwide, Inc. Anti-adherent composition
US10028899B2 (en) 2014-07-31 2018-07-24 Kimberly-Clark Worldwide, Inc. Anti-adherent alcohol-based composition
US10238107B2 (en) 2014-07-31 2019-03-26 Kimberly-Clark Worldwide, Inc. Anti-adherent composition
WO2020070014A1 (fr) * 2018-10-02 2020-04-09 Novozymes A/S Composition de nettoyage comprenant un tensioactif anionique et un polypeptide ayant une activité rnase
US11168287B2 (en) 2016-05-26 2021-11-09 Kimberly-Clark Worldwide, Inc. Anti-adherent compositions and methods of inhibiting the adherence of microbes to a surface
US11737458B2 (en) 2015-04-01 2023-08-29 Kimberly-Clark Worldwide, Inc. Fibrous substrate for capture of gram negative bacteria
US12037497B2 (en) 2016-01-28 2024-07-16 Kimberly-Clark Worldwide, Inc. Anti-adherent composition against DNA viruses and method of inhibiting the adherence of DNA viruses to a surface

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004001590B4 (de) * 2004-01-09 2012-12-06 Gerhard Knapp Verwendung eines Wirkstoffes und einer Kombination aus Wirkstoffen zur Inhibierung von Milbenkot und/oder Schimmelpilzsporen und/oder Pflanzenpollen und -sporen und/oder zur Denaturierung des Keratins von Tierhaaren

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3849254A (en) * 1973-05-31 1974-11-19 Univ Virginia Process for effecting enzymatic reactions in aerosols
DE1667891B2 (de) * 1967-03-16 1980-05-22 Choay S.A., Paris Verwendung von Ribonuclease bei der Schmerzbekämpfung
EP0229866A1 (fr) * 1985-05-10 1987-07-29 Benzon Pharma A/S Enzymes bactériens et leur méthode de production
WO1989011294A1 (fr) * 1988-05-26 1989-11-30 Nika Health Care, Inc. Compose antiviral ou antibacterien et procede d'utilisation
EP0430270A1 (fr) * 1989-12-01 1991-06-05 BEHRINGWERKE Aktiengesellschaft Procédé pour l'inactivation biologique des acides nucléiques
DE4016483A1 (de) * 1990-05-22 1991-11-28 Klinger & Co Dr Verfahren zur bekaempfung von phytopathogenen viren
DE4024530A1 (de) * 1990-08-02 1992-02-06 Klinger & Co Dr Verfahren zur bekaempfung von viren

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1667891B2 (de) * 1967-03-16 1980-05-22 Choay S.A., Paris Verwendung von Ribonuclease bei der Schmerzbekämpfung
US3849254A (en) * 1973-05-31 1974-11-19 Univ Virginia Process for effecting enzymatic reactions in aerosols
EP0229866A1 (fr) * 1985-05-10 1987-07-29 Benzon Pharma A/S Enzymes bactériens et leur méthode de production
WO1989011294A1 (fr) * 1988-05-26 1989-11-30 Nika Health Care, Inc. Compose antiviral ou antibacterien et procede d'utilisation
EP0430270A1 (fr) * 1989-12-01 1991-06-05 BEHRINGWERKE Aktiengesellschaft Procédé pour l'inactivation biologique des acides nucléiques
DE4016483A1 (de) * 1990-05-22 1991-11-28 Klinger & Co Dr Verfahren zur bekaempfung von phytopathogenen viren
DE4024530A1 (de) * 1990-08-02 1992-02-06 Klinger & Co Dr Verfahren zur bekaempfung von viren

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6017046A (en) * 1998-01-21 2000-01-25 Markovic; Vladimir Wheelchair apparatus
KR100454594B1 (ko) * 2002-07-22 2004-11-03 배흥규 라이스 커틀릿 및 그 제조방법
US9969885B2 (en) 2014-07-31 2018-05-15 Kimberly-Clark Worldwide, Inc. Anti-adherent composition
US10028899B2 (en) 2014-07-31 2018-07-24 Kimberly-Clark Worldwide, Inc. Anti-adherent alcohol-based composition
US10238107B2 (en) 2014-07-31 2019-03-26 Kimberly-Clark Worldwide, Inc. Anti-adherent composition
US10292916B2 (en) 2014-07-31 2019-05-21 Kimberly-Clark Worldwide, Inc. Anti-adherent alcohol-based composition
US11737458B2 (en) 2015-04-01 2023-08-29 Kimberly-Clark Worldwide, Inc. Fibrous substrate for capture of gram negative bacteria
US12037497B2 (en) 2016-01-28 2024-07-16 Kimberly-Clark Worldwide, Inc. Anti-adherent composition against DNA viruses and method of inhibiting the adherence of DNA viruses to a surface
US11168287B2 (en) 2016-05-26 2021-11-09 Kimberly-Clark Worldwide, Inc. Anti-adherent compositions and methods of inhibiting the adherence of microbes to a surface
WO2020070014A1 (fr) * 2018-10-02 2020-04-09 Novozymes A/S Composition de nettoyage comprenant un tensioactif anionique et un polypeptide ayant une activité rnase

Also Published As

Publication number Publication date
CA2116661A1 (fr) 1994-01-06
CH682541A5 (de) 1993-10-15
AU3252693A (en) 1994-01-24

Similar Documents

Publication Publication Date Title
CN1041989C (zh) 协同杀菌组合物
US6582683B2 (en) Dermal barrier composition
US7192601B2 (en) Antimicrobial and sporicidal composition
AU7993800A (en) Bioadhesive nanoparticulate compositions having cationic surface stabilizers
EP1530485A1 (fr) Desinfectant a large spectre
CN102488705A (zh) 用于杀灭病毒的皮肤粘膜消毒剂
WO1994000016A1 (fr) Inactivation biochimique de virus a arn
EP1038874A4 (fr) Derives d'oxime et produits chimiques agricoles les contenant
US20040253287A1 (en) Environmentally safe insecticides
US5145663A (en) Biodegradable disinfectant containing anhydrous alcohol and propylene glycol
DK566781A (da) Slibevirksomme midler og deres anvendelse
EP0612216B1 (fr) Compositions phospholipides antimicrobiennes
US8147877B2 (en) Essential oils based disinfecting compositions having tuberculocidal and fungicidal efficacies
US20190351059A1 (en) Antimicrobial insect repellent composition
JP2011246473A (ja) 殺生物剤：殺菌剤、防腐剤、消毒剤及び駆虫剤としてのジアルキルケトンペルオキシドの使用
DE60213361T2 (de) Flüssige antimikrobielle zusammensetzungen
ATE196976T1 (de) Verfahren zur herstellung von wirkstoffhaltigen granulaten
JPS60146827A (ja) 約１より小さいｐｈ値を有する殺菌剤
DE69614398T2 (de) Sterilisierende oder desinfizierende zusammensetzung
CA2022848A1 (fr) Procede de desinfection des tissus musculo-squelettiques et tissus ainsi prepares
BR8901159A (pt) Substancia f-0368 ou um seu sal;processos para produzi-los;composicao;agente preventivo para doencas de plantas;processo para evitar doencas de plantas;desinfetante e materiais para uso em agricultura;processo para cultivar plantas,e microorganismo
JP7121400B2 (ja) 化粧品洗浄剤製品およびその使用
CN113521042A (zh) 一种儿童专用无醇免洗病毒灭活消毒剂及其制备方法
EP0998912B1 (fr) Utilisation de peracides pour la désinfection ou la décontamination des mains
US11225632B1 (en) Cleaning composition for facilitating cleaning surfaces of an object using femtotechnology

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AU BB BG BR CA CS FI HU JP KP KR LK MG MN NO NZ PL RO RU UA US

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE

WWE Wipo information: entry into national phase

Ref document number: 2116661

Country of ref document: CA

121 Ep: the epo has been informed by wipo that ep was designated in this application
122 Ep: pct application non-entry in european phase