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WO1993022983A1 - Clou pour dispositifs de fixation externe - Google Patents

Clou pour dispositifs de fixation externe Download PDF

Info

Publication number
WO1993022983A1
WO1993022983A1 PCT/EP1993/001159 EP9301159W WO9322983A1 WO 1993022983 A1 WO1993022983 A1 WO 1993022983A1 EP 9301159 W EP9301159 W EP 9301159W WO 9322983 A1 WO9322983 A1 WO 9322983A1
Authority
WO
WIPO (PCT)
Prior art keywords
nail
bone
aiding
hydroxyapatite
bone regeneration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP1993/001159
Other languages
English (en)
Inventor
Antonio Moroni
Victor Luis Caja
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
FLAMETAL SpA
Citieffe SRL
Original Assignee
FLAMETAL SpA
Citieffe SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by FLAMETAL SpA, Citieffe SRL filed Critical FLAMETAL SpA
Publication of WO1993022983A1 publication Critical patent/WO1993022983A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/84—Fasteners therefor or fasteners being internal fixation devices
    • A61B17/86—Pins or screws or threaded wires; nuts therefor
    • A61B17/866—Material or manufacture
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/082—Inorganic materials
    • A61L31/086—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00004—(bio)absorbable, (bio)resorbable or resorptive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Definitions

  • the present invention relates to a nail for external fixation devices.
  • External fixation is a method for treating fractures which is based on the application of an external fixation device, constituted by a central body and by a variable number of metallic nails, without surgically affecting the fracture.
  • the central body of the fixation device ensures stability of the reduction of the fracture and in some cases allows to act on the fracture, appropriately modifying its alignment axes, in order to improve reduction of the axial misalignment of the fracture heads.
  • the central body is connected to the bone segments above and below the fracture by the nails.
  • Said nails are rods with a threaded end which is inserted in the bone through the skin and the various soft tissues and grips said bone; the other end is instead connected to the body of the fixation device by means of clamps.
  • One of the main problems of external fixation is constituted by the progressive decrease of the grip of the nails in the bone.
  • the firmness of the grip of the nails in fact decreases in the course of time, and obviously if the functioning of the nails is altered, the entire treatment of the fracture can be compromised.
  • This decrease in mechanical grip is caused by many factors, such as the initial damage produced in the bone as a consequence of the insertion of the nail, the constant forming of fibrous tissue around the metallic nail, the forming of infections, and the effect of the load.
  • a principal object of the present invention is to solve the above problem by providing a nail which has significantly better grip in the bone than conventional ones.
  • a further object of the present invention is to provide a nail wherein improved performance does not negatively affect its low cost.
  • a nail which is characterized in that at least the portion for engaging in the bone is coated with an applied material which has bone regeneration-aiding properties.
  • figure 1 is a view of a nail according to the invention.
  • the nail comprises a stem 1 which ends with a threaded portion 2 which is meant to engage in the bone.
  • the numeral 3 designates the layer of applied bone regeneration-aiding material which covers the threaded portion 2 and also affects the surface of the stem which remains in contact with the soft tissues after the nail has been fixed.
  • Hydroxyapatite or other materials having similar performance are preferably used as the material having bone regeneration-aiding properties. Examples of these other materials are: — hydroxyapatite bound with halogens such as hydroxyfluoroapatite and related mixtures, including hydroxyapatite;
  • the applied material may also be of the absorbable type, particularly when its absorption occurs in a time considered to be shorter than that necessary to perform the task for which it is intended.
  • the coating of bone regeneration-aiding material can also extend to the surface of the nail which is in contact with soft tissues.
  • the thickness of the applied material may be any, the coating of the nail has a thickness on the order of 30-80 microns.
  • the performance of the coating can be improved by using suitable binding agents between the surface of the nail and the applied material.
  • the applied material may be deposited with any known deposition technology, particularly by plasma spray.
  • the bone regeneration-aiding treatment may also be constituted not by a coating but by an impregnation or diffusion, with known methods, of ions or compound elements that aid bone regeneration in the structure of the nail.
  • Nails treated in the above described manner in fact have a significantly greater grip in bone tissue than uncoated ones; it has furthermore been demonstrated that this advantage persists for a long time after in vivo implanting.
  • the basic reason for this behavior is that the applied material, interposed between the bone and the metal, leads to higher values of the initial extraction force, and that the direct contact which occurs between the surface coating of bone-regeneration aiding material and the bone ensures higher values of extraction force after some time.
  • nails coated with bone-regeneration aiding material provide excellent contact between the bone and the surface of the nail.
  • the cortical bone in fact become denser and expands, growing directly in contact with the bone-regeneration aiding material.
  • another significant advantage of coated nails according to the invention is constituted by a reduction in the frequency of infections.
  • the stem can be metallic or composite and may have any configuration.
  • the device can in fact be used successfully also with cylindrical, conical, frustum-shaped and similar stems.

Landscapes

  • Health & Medical Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Materials For Medical Uses (AREA)
  • Surgical Instruments (AREA)

Abstract

Le clou destiné à des dispositifs de fixation externe comprend une tige (1) dont au moins la partie (2) venant au contact de l'os est recouverte d'un matériau appliqué (3) présentant des propriétés aidant à la régénération osseuse, telle que par exemple l'hydroxyapathite.
PCT/EP1993/001159 1992-05-15 1993-05-11 Clou pour dispositifs de fixation externe Ceased WO1993022983A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITB092U000100 1992-05-15
IT92BO000100U IT227861Y1 (it) 1992-05-15 1992-05-15 Fiche per fissatori esterni

Publications (1)

Publication Number Publication Date
WO1993022983A1 true WO1993022983A1 (fr) 1993-11-25

Family

ID=11338096

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1993/001159 Ceased WO1993022983A1 (fr) 1992-05-15 1993-05-11 Clou pour dispositifs de fixation externe

Country Status (2)

Country Link
IT (1) IT227861Y1 (fr)
WO (1) WO1993022983A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2460909A (en) * 2008-01-28 2009-12-23 Mark B Sommers Bone nail with helical ridges
US9161793B2 (en) 1993-01-21 2015-10-20 Acumed Llc Axial tension screw
US9161782B2 (en) 2009-10-16 2015-10-20 DePuy Synthes Products, Inc. Bone anchor assemblies and methods of manufacturing and use thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986003667A1 (fr) * 1984-12-14 1986-07-03 Klaus Draenert Tampon en materiau chirurgical
WO1986003666A1 (fr) * 1984-12-14 1986-07-03 Klaus Draenert Implant destine a la consolidation osseuse et a l'ancrage de tire-fonds, implants et parties d'implant
WO1988003781A1 (fr) * 1986-11-25 1988-06-02 Synthes Ag Dispositif d'osteosynthese
WO1989001767A1 (fr) * 1987-09-02 1989-03-09 Russell Warren Dispositif de fixation chirurgical

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986003667A1 (fr) * 1984-12-14 1986-07-03 Klaus Draenert Tampon en materiau chirurgical
WO1986003666A1 (fr) * 1984-12-14 1986-07-03 Klaus Draenert Implant destine a la consolidation osseuse et a l'ancrage de tire-fonds, implants et parties d'implant
WO1988003781A1 (fr) * 1986-11-25 1988-06-02 Synthes Ag Dispositif d'osteosynthese
WO1989001767A1 (fr) * 1987-09-02 1989-03-09 Russell Warren Dispositif de fixation chirurgical

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9161793B2 (en) 1993-01-21 2015-10-20 Acumed Llc Axial tension screw
GB2460909A (en) * 2008-01-28 2009-12-23 Mark B Sommers Bone nail with helical ridges
GB2460909B (en) * 2008-01-28 2010-09-08 Mark B Sommers Bone Nail
US8092505B2 (en) 2008-01-28 2012-01-10 Acumed Llc Bone nail
US9161782B2 (en) 2009-10-16 2015-10-20 DePuy Synthes Products, Inc. Bone anchor assemblies and methods of manufacturing and use thereof

Also Published As

Publication number Publication date
ITBO920100V0 (it) 1992-05-15
ITBO920100U1 (it) 1993-11-15
IT227861Y1 (it) 1998-01-21

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