[go: up one dir, main page]

WO1993014735A1 - Procede de fabrication pour poches medicales - Google Patents

Procede de fabrication pour poches medicales Download PDF

Info

Publication number
WO1993014735A1
WO1993014735A1 PCT/KR1992/000046 KR9200046W WO9314735A1 WO 1993014735 A1 WO1993014735 A1 WO 1993014735A1 KR 9200046 W KR9200046 W KR 9200046W WO 9314735 A1 WO9314735 A1 WO 9314735A1
Authority
WO
WIPO (PCT)
Prior art keywords
interior
layer
temperature
gelling
exterior
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/KR1992/000046
Other languages
English (en)
Inventor
Won Ho Jin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of WO1993014735A1 publication Critical patent/WO1993014735A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/10—Bag-type containers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C48/00—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
    • B29C48/03—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor characterised by the shape of the extruded material at extrusion
    • B29C48/09—Articles with cross-sections having partially or fully enclosed cavities, e.g. pipes or channels
    • B29C48/10—Articles with cross-sections having partially or fully enclosed cavities, e.g. pipes or channels flexible, e.g. blown foils
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2023/00—Tubular articles
    • B29L2023/005—Hoses, i.e. flexible
    • B29L2023/007—Medical tubes other than catheters

Definitions

  • This invention refers to manufacturing method for medical plastic bag used for drawing, or storing, blood or for preserving physiological saline solutions.
  • Plastic sheeting used in the manufacture of this medical bag can be of the type manufactured by the calender method, or by Ti-Die or cylindrical die: however, sheeting manufactured by means of the calender method of the Ti-Die process require the use fo large facilities, making dust control difficult leading to the creation of many pinholes, in addition to the disadvantage of requiring reforming into bag medical bag is, therefore, generally manufactured by means of cylindrical die.
  • bag is manufactured using a cylindrical die, investment can be reduced and, since the bag is preduced in cylindrical shape, no separate manufacturing process is required to make cylindrical.
  • the inner side of the bag is not exposed, preventing the ingress of any foreign substance, like dust.
  • the bag is rendered somewhat flat due to cohesiveness of the inner part, creating difficulties in the manufacturing process, in that one end of the bag should be closed, and other end connected to a hose.
  • other potential medical problems may arise e.g.bag contents may leak through pinholes created : may be infected by a virus, or liquid contents may evaporate due to bag breathability, causing content properties to change.
  • bag is made of more than two layers, to close pinholes and eliminate cohesiveness of the inner layer, or the inner surface is coated with silicone, or vertical patterns are formed on the inner surface, to prevent the inner walls from sticking together and prevent the plasticizer migreate.
  • This invention therefore, reters to method by which double-layered cylindrical sheeting, measuring 0.3 ⁇ 0.4mm in thickness and 24 ⁇ 60cm in circumference are manufactured for use as medical containers, using a cylindrical die for double-layer molding which has closed pinholes and reduced breathability to suppress evaporation of bag contents.
  • the inner layer of the cylindrical sheeting mads in two layers is formed through high-temperature gelling and non-migreate P.V.C compound in which if both the interior and exterior layers are formed through extrusion molding based no the temperature conditions affecting the exterior layer extrusion molding, the interior layer will have a higher extrusion molding temperature, resulting in al lesser degree of gelling.
  • This is trun, causes somewhat imperfect molding, creating a fine embossing on the interior surface. Cylindrical sheeting with embossing and non-migreated plasticizer thus created prevents the interior surfaceds from sticking together, eliminating other difficulties caused by adhesion of the interior surfaces.
  • the exterior layer can be made using a general type of resin composite which a slightly less smount of plasticizer than that used in the exterior layer is mixed in the interior layer to increase the processing temperature marginally above that of the general resin composite : or the degree of polymerization can be increased in the making of urethene rubber which is non-migreate plasticizer mixed : or, conversely, an amount of process accelerator may be mixed in the exterior part, making the gelling temperature of the exterior layer lower than that of the interior layer.
  • DOP plasticizer was added to 100 parts (weight ratio to be the same thereafter)
  • PVC 6 parts epoxy soybean oil 2 parts CA-ZA stabilizer and 0.3 parts wax : all having in common
  • the polymerization degree 2000 which 60 parts and 58 parts were added to the exterior layer and interior layer respectively and extrusion effected under the condition of gelled extrusion molding (tempe reture of extruding machine: 170°C, and temperature of die : 185°C), after reducing by 2 parts the amount of plasticzer mixed in the interior layer.
  • urethane rubber which is a non-migreate high-polymer plasticizer, or a plasticizer of the ester group, is recommended for the interior resin layer, while the nytril rubber may be replaced by a urethane rubber or a plasticizer of the ester group (p-200 name of product manufactured by Asai Denga industrial Co., Ltd., 2 Jung Mok, Marino Woo-Chi, Nihon Bashi, Juo-ku, Tokyo, Japan).
  • medical bag to be manufactured according to the method of this invention has a thickness of 0.3-0.4mm and width of 12-30mm as a result of extruding the interior part with a mixture of malterials having a little higher gelling temperature, the interior part is marginally insufficiently molded, creating a fine embossing on the interior surfaces. Because of this embossing, and the non-migreating characteristics, there is no sticking phenomenon exhibited in the interior surfaces.

Landscapes

  • Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Extrusion Moulding Of Plastics Or The Like (AREA)
  • Materials For Medical Uses (AREA)

Abstract

L'invention concerne un procédé de fabrication pour poche médicale dans lequel les parois intérieures ne sont pas collées ensemble. Jusqu'à maintenant le silicone a été appliqué, ou des motifs verticaux ont été formés sur la surface intérieure de la poche médicale pour empêcher les parois intérieures de coller ensemble: cependant ces procédés de revêtement silicone ou de formation de motifs verticaux sur les parois intérieures sont peu pratiques, incapables d'éliminer les trous d'aiguille ou de réduire les problèmes de respiration. Cette invention est caractérisée par le fait qu'elle élimine les trous d'aiguille et réduit les problèmes de respiration, grâce à la formation de la poche avec une double couche de feuilles: la couche intérieure est formée avec un gel haute température qui est coagulé à une température plus haute que la température de coagulation du composé de la couche extérieure. Le sac est extrudé et formé à la température d'extrusion de la couche extérieure, résultant en une coagulation moindre du gel haute température de la couche intérieure et en un phénomène de moulage presque incomplet qui, à son tour, crée un gaufrage fin sur les surfaces intérieures, empêchant les parois intérieures de coller ensemble.
PCT/KR1992/000046 1992-01-28 1992-10-07 Procede de fabrication pour poches medicales Ceased WO1993014735A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1019920001154A KR950006000B1 (ko) 1992-01-28 1992-01-28 의료용 튜브의 제조방법
KR1992-1154 1992-01-28

Publications (1)

Publication Number Publication Date
WO1993014735A1 true WO1993014735A1 (fr) 1993-08-05

Family

ID=19328340

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR1992/000046 Ceased WO1993014735A1 (fr) 1992-01-28 1992-10-07 Procede de fabrication pour poches medicales

Country Status (3)

Country Link
KR (1) KR950006000B1 (fr)
DE (1) DE4294717T1 (fr)
WO (1) WO1993014735A1 (fr)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2171669C2 (ru) * 1999-06-29 2001-08-10 Бийский технологический институт Алтайского государственного технического университета им. И.И. Ползунова Способ герметизации пластиковых контейнеров для хранения и переработки крови
RU2283993C1 (ru) * 2005-01-27 2006-09-20 ЗАО "Удел" Способ охлаждения партии полимерных контейнеров с донорской кровью и аппаратура для его осуществления
DE102006058498A1 (de) * 2006-12-12 2008-06-19 Raumedic Ag Verfahren zur Herstellung eines medizinischen Flüssigkeitsbehälters aus flexiblem Kunststoffmaterial, Folienschlauch als Zwischenprodukt für einen derartigen medizinischen Behälter sowie medizinischer Behälter, hergestellt nach einem derartigen Verfahren
US20160243738A1 (en) * 2015-02-19 2016-08-25 Charles Wasyl Katrycz Method and system for integrating branched structures in materials
RU2776569C1 (ru) * 2022-02-17 2022-07-22 Общество с ограниченной ответственностью "Центр ультразвуковых технологий" Устройство ультразвуковой герметизации и сегментации трансфузионных систем

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101505241B1 (ko) * 2012-03-16 2015-03-23 (주)엘지하우시스 Ｐｖｃ 무독 창호용 합성수지 조성물 및 ｐｖｃ 무독 창호

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4212299A (en) * 1977-06-07 1980-07-15 Toppan Printing Co., Ltd. Container bag
GB2070514A (en) * 1980-02-29 1981-09-09 Smith Bros Whitehaven Ltd Method of making packaging
WO1983002226A1 (fr) * 1981-12-22 1983-07-07 Hardy, Peter, Derek Poches en forme de sacs pour contenir des liquides
EP0095526A2 (fr) * 1982-05-28 1983-12-07 TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION Récipients médicaux
EP0216509A2 (fr) * 1985-08-23 1987-04-01 Showa Denko Kabushiki Kaisha Sac médical
EP0302357A2 (fr) * 1987-08-06 1989-02-08 Fresenius AG Unités d'emballage à usage médical

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60259264A (ja) * 1984-06-07 1985-12-21 テルモ株式会社 医療用具

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4212299A (en) * 1977-06-07 1980-07-15 Toppan Printing Co., Ltd. Container bag
GB2070514A (en) * 1980-02-29 1981-09-09 Smith Bros Whitehaven Ltd Method of making packaging
WO1983002226A1 (fr) * 1981-12-22 1983-07-07 Hardy, Peter, Derek Poches en forme de sacs pour contenir des liquides
EP0095526A2 (fr) * 1982-05-28 1983-12-07 TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION Récipients médicaux
EP0216509A2 (fr) * 1985-08-23 1987-04-01 Showa Denko Kabushiki Kaisha Sac médical
EP0302357A2 (fr) * 1987-08-06 1989-02-08 Fresenius AG Unités d'emballage à usage médical

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2171669C2 (ru) * 1999-06-29 2001-08-10 Бийский технологический институт Алтайского государственного технического университета им. И.И. Ползунова Способ герметизации пластиковых контейнеров для хранения и переработки крови
RU2283993C1 (ru) * 2005-01-27 2006-09-20 ЗАО "Удел" Способ охлаждения партии полимерных контейнеров с донорской кровью и аппаратура для его осуществления
DE102006058498A1 (de) * 2006-12-12 2008-06-19 Raumedic Ag Verfahren zur Herstellung eines medizinischen Flüssigkeitsbehälters aus flexiblem Kunststoffmaterial, Folienschlauch als Zwischenprodukt für einen derartigen medizinischen Behälter sowie medizinischer Behälter, hergestellt nach einem derartigen Verfahren
US8679601B2 (en) 2006-12-12 2014-03-25 Raumedic Ag Method of producing a medical fluid container from flexible plastic material, film tubing as intermediate product for a fluid container of this type and medical container produced according to a method of this type
US20160243738A1 (en) * 2015-02-19 2016-08-25 Charles Wasyl Katrycz Method and system for integrating branched structures in materials
US10245762B2 (en) * 2015-02-19 2019-04-02 Charles Wasyl Katrycz Method and system for integrating branched structures in materials
RU2776569C1 (ru) * 2022-02-17 2022-07-22 Общество с ограниченной ответственностью "Центр ультразвуковых технологий" Устройство ультразвуковой герметизации и сегментации трансфузионных систем

Also Published As

Publication number Publication date
DE4294717T1 (de) 1994-01-13
KR930016232A (ko) 1993-08-26
KR950006000B1 (ko) 1995-06-07

Similar Documents

Publication Publication Date Title
US4731266A (en) Water-resistant polyvinyl alcohol film and its application to the preparation of gas-impermeable composite articles
US5733617A (en) Packaging made of composite plastic exhibiting a soft feel effect
US4948643A (en) Flexible medical solution tubing
US5139878A (en) Multilayer film constructions
SE458859B (sv) Syntetisk hartskomposition innehaallande en hydrerad blocksampolymer och anvaending daerav foer livsmedelsfoerpackningar eller medicinska anordningar
US4243724A (en) Thermoplastic multi-layer film
KR960033796A (ko) 공기 주입 타이어 및 이의 제조방법
CN106240102B (zh) 一种五层共挤吹塑薄膜及其制备工艺与应用
JPH021506B2 (fr)
WO1993014735A1 (fr) Procede de fabrication pour poches medicales
US3449479A (en) Method for coating the interior surface of a polyolefin article with an impermeable polymer
JP2590033B2 (ja) 多層ブロー成形容器
US3017670A (en) Process for producing plastic articles
US4613531A (en) Layered thermoplastic articles and method for forming
EP0210108A2 (fr) Procédé pour la production de feuilles cylindriques en matière thermoplastique ayant une surface interne rugueuse et dispositif
CA1300839C (fr) Pellicules a fortes proprietes de barriere
JPH0473142A (ja) 積層成形体およびその製造方法
JPH033460Y2 (fr)
JPH04259545A (ja) 燃料系ホースとその製造方法
JP3466720B2 (ja) 生分解性シート及びその熱成形物
JPH0465855B2 (fr)
AU631974B2 (en) Method of and apparatus for manufacturing tubular thermoplastic resin film having a rough inner surface
US5248472A (en) Method of and apparatus for manufacturing tubular thermoplastic resin film having a rough inner surface
JP3755937B2 (ja) 柔軟性プラスチックによる薬品包装体
JPS5810210B2 (ja) 多層中空成形容器の製造方法

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): DE RU US

ENP Entry into the national phase

Ref document number: 1993 119187

Country of ref document: US

Date of ref document: 19930927

Kind code of ref document: A

RET De translation (de og part 6b)

Ref document number: 4294717

Country of ref document: DE

Date of ref document: 19940113

WWE Wipo information: entry into national phase

Ref document number: 4294717

Country of ref document: DE