WO1992006188A3 - Polymerase d'adn thermostable - Google Patents
Polymerase d'adn thermostable Download PDFInfo
- Publication number
- WO1992006188A3 WO1992006188A3 PCT/US1991/007084 US9107084W WO9206188A3 WO 1992006188 A3 WO1992006188 A3 WO 1992006188A3 US 9107084 W US9107084 W US 9107084W WO 9206188 A3 WO9206188 A3 WO 9206188A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- dna polymerase
- thermostable dna
- taq dna
- lacks
- encodes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
- C12N9/1252—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
- Y10S530/825—Bacteria
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE91920050T DE553264T1 (de) | 1990-10-05 | 1991-09-27 | Thermostabile dna polymerase. |
| JP3518348A JPH06502303A (ja) | 1990-10-05 | 1991-09-27 | 熱安定性dnaポリメラーゼ |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US59463790A | 1990-10-05 | 1990-10-05 | |
| US594,637 | 1990-10-05 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO1992006188A2 WO1992006188A2 (fr) | 1992-04-16 |
| WO1992006188A3 true WO1992006188A3 (fr) | 1992-10-29 |
Family
ID=24379740
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/US1991/007084 WO1992006188A2 (fr) | 1990-10-05 | 1991-09-27 | Polymerase d'adn thermostable |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5616494A (fr) |
| EP (1) | EP0553264A4 (fr) |
| JP (1) | JPH06502303A (fr) |
| AU (1) | AU8906091A (fr) |
| DE (1) | DE553264T1 (fr) |
| WO (1) | WO1992006188A2 (fr) |
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| US8945884B2 (en) | 2000-12-11 | 2015-02-03 | Life Technologies Corporation | Methods and compositions for synthesis of nucleic acid molecules using multiplerecognition sites |
| US9358300B2 (en) | 1998-11-12 | 2016-06-07 | Life Technologies Corporation | Transfection reagents |
| US9376709B2 (en) | 2010-07-26 | 2016-06-28 | Biomatrica, Inc. | Compositions for stabilizing DNA and RNA in blood and other biological samples during shipping and storage at ambient temperatures |
| US9725703B2 (en) | 2012-12-20 | 2017-08-08 | Biomatrica, Inc. | Formulations and methods for stabilizing PCR reagents |
| US10064404B2 (en) | 2014-06-10 | 2018-09-04 | Biomatrica, Inc. | Stabilization of thrombocytes at ambient temperatures |
| US10568317B2 (en) | 2015-12-08 | 2020-02-25 | Biomatrica, Inc. | Reduction of erythrocyte sedimentation rate |
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| US5795762A (en) * | 1986-08-22 | 1998-08-18 | Roche Molecular Systems, Inc. | 5' to 3' exonuclease mutations of thermostable DNA polymerases |
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| DK0550687T3 (da) * | 1990-09-28 | 1999-12-13 | Hoffmann La Roche | 5' til 3'-exonukleasemutationer af termostabile DNA-polymeraser |
| US5436149A (en) * | 1993-02-19 | 1995-07-25 | Barnes; Wayne M. | Thermostable DNA polymerase with enhanced thermostability and enhanced length and efficiency of primer extension |
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| US6100078A (en) * | 1994-04-01 | 2000-08-08 | Gen-Probe Incorporated | Purified DNA polymerase from bacillus stearothermophilus ATCC 12980 |
| US5885813A (en) * | 1995-05-31 | 1999-03-23 | Amersham Life Science, Inc. | Thermostable DNA polymerases |
| US6077664A (en) * | 1995-06-07 | 2000-06-20 | Promega Corporation | Thermophilic DNA polymerases from Thermotoga neapolitana |
| US6001645A (en) * | 1995-06-07 | 1999-12-14 | Promega Corporation | Thermophilic DNA polymerases from thermotoga neapolitana |
| EP2264045B1 (fr) | 1996-08-14 | 2015-10-21 | Life Technologies Corporation | Composition pour l'amplification et pour la séquenciation de l'ADN |
| US6291164B1 (en) | 1996-11-22 | 2001-09-18 | Invitrogen Corporation | Methods for preventing inhibition of nucleic acid synthesis by pyrophosphate |
| WO1998042860A1 (fr) | 1997-03-21 | 1998-10-01 | Stratagene | Extraits de facteur stimulant la polymerase (pef), complexes de proteines pef, proteine pef isolee, et procedes de purification et d'identification |
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| US6130045A (en) * | 1998-06-11 | 2000-10-10 | Clontech Laboratories, Inc. | Thermostable polymerase |
| AU5008900A (en) * | 1999-05-12 | 2000-11-21 | Invitrogen Corporation | Compositions and methods for enhanced sensitivity and specificity of nucleic acid synthesis |
| NZ515673A (en) | 1999-05-21 | 2004-03-26 | Invitrogen Corp | Compositions and methods for labeling of nucleic acid molecules |
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| DK1250453T3 (da) | 1999-12-10 | 2008-08-11 | Invitrogen Corp | Anvendelse af multiple rekombinations-sites med unik specificitet i rekombinationskloning |
| US6632645B1 (en) | 2000-03-02 | 2003-10-14 | Promega Corporation | Thermophilic DNA polymerases from Thermoactinomyces vulgaris |
| US6436677B1 (en) | 2000-03-02 | 2002-08-20 | Promega Corporation | Method of reverse transcription |
| NZ522500A (en) | 2000-05-26 | 2004-10-29 | Invitrogen Corp | Thermostable reverse transcriptases and uses thereof |
| US6214557B1 (en) | 2000-06-06 | 2001-04-10 | Washington University | Cold sensitive mutant DNA polymerases |
| WO2002046372A1 (fr) | 2000-12-08 | 2002-06-13 | Invitrogen Corporation | Methodes et compositions destinees a la synthese de molecules d'acide nucleique a l'aide de sites de reconnaissance multiples |
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| US20050042629A1 (en) | 2002-09-13 | 2005-02-24 | Applera Corporation | Thermus scotoductus nucleic acid polymerases |
| US20030165859A1 (en) | 2001-10-23 | 2003-09-04 | Invitrogen Corporation | Primers and methods for the detection and discrimination of nucleic acids |
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| WO2003048308A2 (fr) | 2001-11-30 | 2003-06-12 | Applera Corporation | Polymérases d'acide nucléique du thermus brockanius |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1989006691A2 (fr) * | 1988-01-12 | 1989-07-27 | Cetus Corporation | Enzyme thermostable purifiee |
| WO1991002090A1 (fr) * | 1989-08-03 | 1991-02-21 | Promega Corporation | Polymerase d'adn de taq modifie |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5079352A (en) * | 1986-08-22 | 1992-01-07 | Cetus Corporation | Purified thermostable enzyme |
| US4889818A (en) * | 1986-08-22 | 1989-12-26 | Cetus Corporation | Purified thermostable enzyme |
| DE69030386T2 (de) * | 1989-12-22 | 1997-10-09 | F. Hoffmann-La Roche Ag, Basel | Bei hoher temperatur aktive reverse transkriptasen |
| DK0550687T3 (da) * | 1990-09-28 | 1999-12-13 | Hoffmann La Roche | 5' til 3'-exonukleasemutationer af termostabile DNA-polymeraser |
-
1991
- 1991-09-27 DE DE91920050T patent/DE553264T1/de active Pending
- 1991-09-27 AU AU89060/91A patent/AU8906091A/en not_active Abandoned
- 1991-09-27 JP JP3518348A patent/JPH06502303A/ja active Pending
- 1991-09-27 WO PCT/US1991/007084 patent/WO1992006188A2/fr not_active Application Discontinuation
- 1991-09-27 EP EP19910920050 patent/EP0553264A4/en not_active Withdrawn
-
1994
- 1994-07-11 US US08/274,205 patent/US5616494A/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1989006691A2 (fr) * | 1988-01-12 | 1989-07-27 | Cetus Corporation | Enzyme thermostable purifiee |
| WO1991002090A1 (fr) * | 1989-08-03 | 1991-02-21 | Promega Corporation | Polymerase d'adn de taq modifie |
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| See also references of EP0553264A4 * |
| T. MANIATIS et al., "Molecular Cloning, a Laboratory Manual", published 1982 by McGraw-Hill (N.Y.), see pages 108-114. * |
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Also Published As
| Publication number | Publication date |
|---|---|
| AU8906091A (en) | 1992-04-28 |
| EP0553264A4 (en) | 1994-07-13 |
| DE553264T1 (de) | 1994-04-28 |
| JPH06502303A (ja) | 1994-03-17 |
| WO1992006188A2 (fr) | 1992-04-16 |
| EP0553264A1 (fr) | 1993-08-04 |
| US5616494A (en) | 1997-04-01 |
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