[go: up one dir, main page]

WO1991017777A3 - Injectable bioactive glass compositions and methods for tissue reconstruction - Google Patents

Injectable bioactive glass compositions and methods for tissue reconstruction Download PDF

Info

Publication number
WO1991017777A3
WO1991017777A3 PCT/US1991/003596 US9103596W WO9117777A3 WO 1991017777 A3 WO1991017777 A3 WO 1991017777A3 US 9103596 W US9103596 W US 9103596W WO 9117777 A3 WO9117777 A3 WO 9117777A3
Authority
WO
WIPO (PCT)
Prior art keywords
bioactive glass
methods
glass compositions
tissue reconstruction
injectable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1991/003596
Other languages
French (fr)
Other versions
WO1991017777A2 (en
Inventor
Dixon R Walker
June Wilson Hench
Marc Ramer
Larry L Hench
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Florida
Original Assignee
University of Florida
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Florida filed Critical University of Florida
Publication of WO1991017777A2 publication Critical patent/WO1991017777A2/en
Publication of WO1991017777A3 publication Critical patent/WO1991017777A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C4/00—Compositions for glass with special properties
    • C03C4/0007—Compositions for glass with special properties for biologically-compatible glass
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0047—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L24/0073—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix
    • A61L24/0084—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix containing fillers of phosphorus-containing inorganic compounds, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Materials Engineering (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Surgery (AREA)
  • Composite Materials (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Geochemistry & Mineralogy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials For Medical Uses (AREA)
  • Glass Compositions (AREA)

Abstract

An injectable hyaluronic acid particulate bioactive glass composition useful for the repair, reconstruction, replacement, augmentation or reconfiguration of hard bone or soft tissue anatomic structure, the composition of the glass falling within Region E of the compositional boundary diagram of Fig. 4.
PCT/US1991/003596 1990-05-22 1991-05-22 Injectable bioactive glass compositions and methods for tissue reconstruction Ceased WO1991017777A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52663890A 1990-05-22 1990-05-22
US526,638 1990-05-22

Publications (2)

Publication Number Publication Date
WO1991017777A2 WO1991017777A2 (en) 1991-11-28
WO1991017777A3 true WO1991017777A3 (en) 1992-01-09

Family

ID=24098137

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1991/003596 Ceased WO1991017777A2 (en) 1990-05-22 1991-05-22 Injectable bioactive glass compositions and methods for tissue reconstruction

Country Status (1)

Country Link
WO (1) WO1991017777A2 (en)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6984623B2 (en) 1993-12-07 2006-01-10 Genetics, Institute Institute, LLC. Tendon-inducing compositions
US7091007B2 (en) 1993-09-17 2006-08-15 Genetics Institute, Llc DNA molecules encoding BMP receptor proteins
US7189392B1 (en) 1999-10-15 2007-03-13 Genetics Institute, Llc Injectable carrier formulations of hyaluronic acid derivatives for delivery of osteogenic proteins
US7217691B2 (en) 1986-07-01 2007-05-15 Genetics Institute, Llc Methods of treatment of periodontal disease
US7226587B2 (en) 2001-06-01 2007-06-05 Wyeth Compositions and methods for systemic administration of sequences encoding bone morphogenetic proteins
US7323445B2 (en) 1999-02-01 2008-01-29 Genetics Institute, Llc Methods and compositions for healing and repair of articular cartilage
US7413753B2 (en) 2001-06-08 2008-08-19 Wyeth Calcium phosphate delivery vehicles for osteoinductive proteins
US9352046B2 (en) 2006-02-06 2016-05-31 Merz North America, Inc. Implantation compositions for use in tissue augmentation
US11464740B2 (en) 2019-04-29 2022-10-11 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Method and devices for delivering therapeutics by oral, respiratory, mucosal, transdermal routes

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6537574B1 (en) 1992-02-11 2003-03-25 Bioform, Inc. Soft tissue augmentation material
US7060287B1 (en) 1992-02-11 2006-06-13 Bioform Inc. Tissue augmentation material and method
US7968110B2 (en) 1992-02-11 2011-06-28 Merz Aesthetics, Inc. Tissue augmentation material and method
IT1259090B (en) * 1992-04-17 1996-03-11 Fidia Spa BIOMATERIALS FOR BONE PROSTHESIS
US5591453A (en) * 1994-07-27 1997-01-07 The Trustees Of The University Of Pennsylvania Incorporation of biologically active molecules into bioactive glasses
FI104881B (en) * 1994-10-06 2000-04-28 Bioxid Oy Process for preparing new compositions containing silicon-containing glass
US5591724A (en) * 1995-02-14 1997-01-07 Bioniche Inc. Method for treating the urinary bladder and associated structures using hyaluronic acid
US5830480A (en) * 1996-05-09 1998-11-03 The Trustees Of The University Of Pennsylvania Stabilization of sol-gel derived silica-based glass
ATE307620T1 (en) * 1997-04-05 2005-11-15 Tyco Healthcare IMPLANT MATERIAL WITH GLASS PARTICLES
US5977204A (en) * 1997-04-11 1999-11-02 Osteobiologics, Inc. Biodegradable implant material comprising bioactive ceramic
US7524335B2 (en) 1997-05-30 2009-04-28 Smith & Nephew, Inc. Fiber-reinforced, porous, biodegradable implant device
JP2002524203A (en) * 1998-09-10 2002-08-06 ユーエスバイオマテリアルズ コーポレイション Anti-inflammatory and antibacterial uses of bioactive glass compositions
WO2000066086A1 (en) * 1999-04-29 2000-11-09 Usbiomaterials Corporation Anti-inflammatory bioactive glass particulates
CA2380932A1 (en) * 1999-08-13 2001-02-22 Bioform Inc. Tissue augmentation material and methods
US6479565B1 (en) 1999-08-16 2002-11-12 Harold R. Stanley Bioactive ceramic cement
EP1454640A3 (en) * 1999-10-15 2004-09-22 Genetics Institute, LLC Formulations of hyaluronic acid for delivery of osteogenic proteins
CN1665525A (en) 2002-05-17 2005-09-07 惠氏公司 Injectable solid hyaluronic acid carriers for delivery of osteogenic proteins
CA2496449C (en) 2002-07-31 2011-11-15 Dentsply International Inc. Bone repair putty comprising porous particulate and carrier gel
US8876532B2 (en) 2002-07-31 2014-11-04 Dentsply International Inc. Bone repair putty
FR2850282B1 (en) * 2003-01-27 2007-04-06 Jerome Asius INJECTABLE IMPLANT BASED ON CERAMIC FOR THE FILLING OF WRINKLES, CUTANEOUS DEPRESSIONS AND SCARS, AND ITS PREPARATION
JP5298010B2 (en) 2006-05-26 2013-09-25 バクスター・インターナショナル・インコーポレイテッド Fibrin composition for injection for bone formation
WO2008031194A1 (en) * 2006-09-13 2008-03-20 Enhance Skin Products, Inc. Cosmetic composition for the treatment of skin and methods thereof
GB0618215D0 (en) * 2006-09-15 2006-10-25 Novathera Ltd Composite material
EP1903012B1 (en) 2006-09-20 2009-12-23 Inion Oy Bioactive glass compositions
BRPI0811035B8 (en) 2007-04-23 2021-05-25 Baxter Healthcare Sa fibrin compositions containing strontium compounds
CA2725253A1 (en) * 2008-05-27 2009-12-03 Imperial Innovations Limited Process for producing porous scaffolds from sinterable glass
GB0911365D0 (en) 2009-06-30 2009-08-12 Bioceramic Therapeutics Ltd Multicomponent glasses for use as coatings and in personal care products
CN113413484B (en) * 2021-06-21 2023-02-10 浙江苏嘉医疗器械股份有限公司 Implant material for human soft tissue filling
CN116942905A (en) * 2023-06-12 2023-10-27 上海诺帮生物科技有限公司 Facial plastic injection filling material and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0251695A2 (en) * 1986-06-25 1988-01-07 Collagen Corporation Injectable implant composition having improved intrudability
EP0291177A2 (en) * 1987-05-06 1988-11-17 Biomatrix, Inc. Novel compositions for percutaneous embolization

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0251695A2 (en) * 1986-06-25 1988-01-07 Collagen Corporation Injectable implant composition having improved intrudability
EP0291177A2 (en) * 1987-05-06 1988-11-17 Biomatrix, Inc. Novel compositions for percutaneous embolization

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7217691B2 (en) 1986-07-01 2007-05-15 Genetics Institute, Llc Methods of treatment of periodontal disease
US7300772B2 (en) 1986-07-01 2007-11-27 Genetics Institute, Llc BMP products
US7091007B2 (en) 1993-09-17 2006-08-15 Genetics Institute, Llc DNA molecules encoding BMP receptor proteins
US6984623B2 (en) 1993-12-07 2006-01-10 Genetics, Institute Institute, LLC. Tendon-inducing compositions
US7365052B2 (en) 1993-12-07 2008-04-29 Genetics Institute, Llc. Tendon-inducing methods
US7323445B2 (en) 1999-02-01 2008-01-29 Genetics Institute, Llc Methods and compositions for healing and repair of articular cartilage
US7189392B1 (en) 1999-10-15 2007-03-13 Genetics Institute, Llc Injectable carrier formulations of hyaluronic acid derivatives for delivery of osteogenic proteins
US7226587B2 (en) 2001-06-01 2007-06-05 Wyeth Compositions and methods for systemic administration of sequences encoding bone morphogenetic proteins
US7413753B2 (en) 2001-06-08 2008-08-19 Wyeth Calcium phosphate delivery vehicles for osteoinductive proteins
US9352046B2 (en) 2006-02-06 2016-05-31 Merz North America, Inc. Implantation compositions for use in tissue augmentation
US11464740B2 (en) 2019-04-29 2022-10-11 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Method and devices for delivering therapeutics by oral, respiratory, mucosal, transdermal routes

Also Published As

Publication number Publication date
WO1991017777A2 (en) 1991-11-28

Similar Documents

Publication Publication Date Title
WO1991017777A3 (en) Injectable bioactive glass compositions and methods for tissue reconstruction
FI885235L (en) IMPLANTS SOM ERSAETTER EN LED ELLER EN DEL AV BENVAEVNAD MED KONSTGJORT MATERIAL.
EP0361896A3 (en) Method for improving implant fixation
AU7724696A (en) Bioactive composite material for repair of hard and soft tissues
EP1142581A3 (en) Tissue sealant and growth factor containing compositions that promote accelerated wound healing
CA2284098A1 (en) Osteogenic devices and methods of use thereof for repair of bone
ATE70710T1 (en) METALLIC INTERVERTEBRAL PROSTHESIS.
DE69113746D1 (en) Partially cemented femoral prosthesis.
DE59102631D1 (en) Bone tissue implant.
AU5841090A (en) Sulphated polysaccharides, anticoagulant agent and anticomplementary agent obtained from brown algae fucuses and method of obtaining same
WO1995016035A3 (en) Bmp-12, bmp-13 and tendon-inducing compositions thereof
AU6008890A (en) Bipolar femoral implant
IT1227847B (en) EQUIPMENT FOR THE CORRECT FEMORAL RESECTION AND FOR THE APPLICATION OF REPLACEMENT PROSTHESES OF THE KNEE ARTICULATION.
ATE357193T1 (en) BIOACTIVE LOAD-BEARING COMPOSITIONS FOR BONE COMPOUNDS
AU583443B2 (en) Porous hydroxyl apatite derived from lime-encrusting algae
EP1230930A3 (en) Bmp-9 compositions
CA2041394A1 (en) Osteogenic composition and implant containing same
ATE121633T1 (en) BONE REPLACEMENT PART MADE OF GLASS IONOMER CEMENT.
EP1690874A3 (en) BMP-12, BMP-13 and tendon-inducing compositions thereof
EP0747067A3 (en) Moldable collagen compositions for hard tissue repair and augmentation
DE68913991D1 (en) IMPLANT FOR USE IN BONE SURGERY.
DE3690341D2 (en) Bone cement
PT1148897E (en) METHODS AND COMPOSITIONS FOR HEALING AND REPAIR OF JOINT CARTILAGE
ITMI922913A0 (en) PROSTHETIC CUTE STRUCTURE, FOR THE RECONSTRUCTION OF THE ACETABULUS IN TOTAL HIP PROSTHESIS.
Heimke Bioinert and bioactive ceramics in orthopaedic surgery

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): CA JP

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): AT BE CH DE DK ES FR GB GR IT LU NL SE

AK Designated states

Kind code of ref document: A3

Designated state(s): CA JP

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): AT BE CH DE DK ES FR GB GR IT LU NL SE

NENP Non-entry into the national phase

Ref country code: CA

122 Ep: pct application non-entry in european phase