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WO1991001001A1 - Detecteur permettant de controler des composes de faible poids moleculaire - Google Patents

Detecteur permettant de controler des composes de faible poids moleculaire Download PDF

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Publication number
WO1991001001A1
WO1991001001A1 PCT/GB1990/001029 GB9001029W WO9101001A1 WO 1991001001 A1 WO1991001001 A1 WO 1991001001A1 GB 9001029 W GB9001029 W GB 9001029W WO 9101001 A1 WO9101001 A1 WO 9101001A1
Authority
WO
WIPO (PCT)
Prior art keywords
molecular weight
detector
low molecular
reagent
adsorber
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB1990/001029
Other languages
English (en)
Inventor
Stephen Clifford Woods
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UK Secretary of State for Defence
Original Assignee
UK Secretary of State for Defence
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898915495A external-priority patent/GB8915495D0/en
Priority claimed from GB898916570A external-priority patent/GB8916570D0/en
Priority claimed from GB909005217A external-priority patent/GB9005217D0/en
Application filed by UK Secretary of State for Defence filed Critical UK Secretary of State for Defence
Publication of WO1991001001A1 publication Critical patent/WO1991001001A1/fr
Priority to GB9127168A priority Critical patent/GB2251070B/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/405—Concentrating samples by adsorption or absorption
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N31/00—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
    • G01N31/22—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using chemical indicators
    • G01N31/223—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using chemical indicators for investigating presence of specific gases or aerosols
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/98—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving alcohol, e.g. ethanol in breath
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/22—Devices for withdrawing samples in the gaseous state
    • G01N1/2202—Devices for withdrawing samples in the gaseous state involving separation of sample components during sampling
    • G01N1/2214—Devices for withdrawing samples in the gaseous state involving separation of sample components during sampling by sorption

Definitions

  • the invention relates to the detection of low molecular weight compoundsr especially ethanol andmethanol/ in the presence of highermolecularweight compounds and is particularly but not exclusively related to a methanol detector for atmosphere monitoring in closed environments.
  • Methanol (CH30H) is a toxicsubstanceandwhenpresentinclosedenvironments thereisaneedtoroutinelymonitortheair. Amoni ormustbeableto signal that the ambient level of methanol is less than a maximum permissible concentration.
  • a commercially availableDraeger detector tube Methanol 50/a
  • Methanol 50/a can be used tomonitor methanol in the range 50 to 3000 ppm.
  • Other tubes are available for themonitoringof other compounds.
  • the detector itself consists of a narrow bore tube containing a precleansing layer of drying agent followed by crystals impregnated with an orange Chromium (Cr(VI)) compound.
  • Cr(VI) Chromium
  • a sample of air of standard volume is drawn through the detector tube by means of a bellows pump.
  • the presence of methanol in that sample causes a colour change in the tube fromorange to black.
  • Thelength of theblack stain thendetermines the amount of methanol present in the sample for the given volume of air.
  • the detection process is illustrated by:
  • An object of the present invention is to provide a means to detect low molecular weight compounds when present in a sample with higher molecular weightcontaminants.
  • Afurtherobjectofthepresentinventionisto provide ameanstomonitormethanol inthepresenceofnoctane.
  • Ayetfurtherobject is to provide a means to detect ethanol in the presence of other organic species.
  • the invention provides a detector for monitoring low molecular weight compounds in the presence of higher molecular weight species comprising: a porous adsorber having relatively low retention for the low molecular weight co ⁇ pounds and relatively high retention for highermolecularweight species; and a reagent which undergoes a colour change on reaction with low molecular weight compounds; the arrangement being such that the adsorber and reagent are contained such that a sampleofair canbepassedthroughtheadsorberbeforepassingthrough the reagent, th amount of low molecular weight compound being calculable from the amount of reagent which changes colour.
  • lowmolecularweightcompound canbe referingtoeitherorganicor inorganic compounds.
  • the low molecular weight compounds are organic Compounds.
  • theorganiccompounds areeithermethanol or ethanol.
  • the lowmolecularweightcompound isanorganiccompound itpreferably contains between1 and5 carbonatomsandmaybe straightchainoroptionally branched.
  • the compounds may also be substituted. Typical groups of compounds would be Cj to C5 alkanes, alkenes, amines, alcohols, aldehydes, ketones organo-halides, such as vinyl chloride, etc.
  • SUBSTITUTE SHEET molecular weight compound is inorganic it will preferably comprise 2 to 4 atoms and typical examples could includeNCfc, S02, C02, NO, CO etc.
  • Higher molecularweight compounds referstocompoundscontainingmore than5 atoms. Thesevalues are thosewhichare generally applicable to theporous adsorber Tenax andwhere other adsorbers are used thetypesofcompoundsand retention on the adsorber on the basis ofmolecularweightmayvary.
  • the reagent isas specificaspossibletothecompoundsorclasses of compounds which require detection.
  • the reagent is a Chromium (VI) compound which changes colour from orange to black on reaction with methanol or ethanol.
  • the Chromium (VT) compound is impregnated on crystalscontainedwithinatubewithwiregauzesbeingprovidedtoretainthe crystals.
  • a drying agent may also be included in the tube to removewater from the air sample before passing over the reagent.
  • the adsorber is a porous powdered polymer, poly 2,6 diphe ⁇ l-p-phe ⁇ ylene oxide which may be retained by glass wool plugs.
  • the adsorber may be contained withinthesametubeasthereagentorinasecondtubewhichisconnectableto thereagenttube. Inapreferredarrangementthereagentandadsorbermaybe sealed before air sairpling and a pumpmeans is provided to draw a standard volume of air sample through the detector.
  • the reagent tube 10 available from Draeger, is a narrow-bore tube partly filled with orange Chromium (VI) compound 12, retained by plugs 13 ofwire.
  • VI Chromium
  • SUBSTITUTE SHEET show that Tenax selectively removes the n octane, thereby removing amajor cross sensitivity problem when detecting methanol.

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)

Abstract

Un détecteur permettant de contrôler des composés de faible poids moléculaire et tout particulièrement les alcools éthanol et méthanol dans des milieux où des contaminants de poids moléculaire supérieur peuvent également être présents. L'on fait passer des échantillons de gaz à travers un absorbant poreux qui présente une rétention relativement faible pour des composés tels que le méthanol et éthanol et une rétention relativement élevée pour des espèces de poids moléculaire plus élevé. L'on fait passer la partie de l'échantillon qui n'est pas retenue par l'absorbant à travers un réactif qui subit une variation de couleur due aux composés de faible poids moléculaire, le degré de variation de couleur étant caractéristique de la quantité de composé de faible poids moléculaire présente. L'invention s'applique en particulier au contrôle de la concentration d'alcools organiques de faible poids moléculaire tel que le méthanol et éthanol.
PCT/GB1990/001029 1989-07-06 1990-07-04 Detecteur permettant de controler des composes de faible poids moleculaire Ceased WO1991001001A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB9127168A GB2251070B (en) 1989-07-06 1991-12-20 A detector for monitoring low molecular weight compounds

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB8915495.9 1989-07-06
GB898915495A GB8915495D0 (en) 1989-07-06 1989-07-06 Methanol monitor
GB8916570.8 1989-07-20
GB898916570A GB8916570D0 (en) 1989-07-20 1989-07-20 Methanol monitor
GB9005217.6 1990-03-08
GB909005217A GB9005217D0 (en) 1990-03-08 1990-03-08 Compound detector

Publications (1)

Publication Number Publication Date
WO1991001001A1 true WO1991001001A1 (fr) 1991-01-24

Family

ID=27264566

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1990/001029 Ceased WO1991001001A1 (fr) 1989-07-06 1990-07-04 Detecteur permettant de controler des composes de faible poids moleculaire

Country Status (2)

Country Link
EP (1) EP0485410A1 (fr)
WO (1) WO1991001001A1 (fr)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994001753A1 (fr) * 1992-07-13 1994-01-20 The Broken Hill Proprietary Company Limited Dispositif d'echantillonnage pour emissions de matieres particulaires ou de vapeurs en suspension dans l'air
US5354749A (en) * 1992-05-12 1994-10-11 Bayer Aktiengesellschaft Sulfonylbenzyl-substituted benzo- and pyridopyridones
ES2065268A1 (es) * 1993-05-04 1995-02-01 Univ Madrid Complutense Sensor optico luminiscente.
US5407942A (en) * 1992-05-12 1995-04-18 Bayer Aktiengesellschaft Biphenylmethyl-substituted pyridones
US5596006A (en) * 1992-10-23 1997-01-21 Bayer Aktiengesellschaft Trisubstituted biphenyls
EP0971225A3 (fr) * 1998-07-09 2000-04-05 HTE GmbH, The high throughput experimentation company Dispositif de détection d'un produit dans l'écoulement d'échappement d'une matière catalytique d'une pluralité de matières catalytiques
US12196727B2 (en) 2019-01-11 2025-01-14 Eth Zurich Device and method for detecting an analyte

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0042683A1 (fr) * 1980-06-24 1981-12-30 National Research Development Corporation Procédé de fabrication de tubes de test à adsorption de gaz
WO1987001204A1 (fr) * 1985-08-15 1987-02-26 Global Geochemistry Corporation Analyse chimique par modulation controlee de l'echantillon et correlation de la detection
EP0213278A2 (fr) * 1985-09-05 1987-03-11 Drägerwerk Aktiengesellschaft Dispositif de prélèvement d'échantillons de gaz à diffusion

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0042683A1 (fr) * 1980-06-24 1981-12-30 National Research Development Corporation Procédé de fabrication de tubes de test à adsorption de gaz
WO1987001204A1 (fr) * 1985-08-15 1987-02-26 Global Geochemistry Corporation Analyse chimique par modulation controlee de l'echantillon et correlation de la detection
EP0213278A2 (fr) * 1985-09-05 1987-03-11 Drägerwerk Aktiengesellschaft Dispositif de prélèvement d'échantillons de gaz à diffusion

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5354749A (en) * 1992-05-12 1994-10-11 Bayer Aktiengesellschaft Sulfonylbenzyl-substituted benzo- and pyridopyridones
US5407942A (en) * 1992-05-12 1995-04-18 Bayer Aktiengesellschaft Biphenylmethyl-substituted pyridones
WO1994001753A1 (fr) * 1992-07-13 1994-01-20 The Broken Hill Proprietary Company Limited Dispositif d'echantillonnage pour emissions de matieres particulaires ou de vapeurs en suspension dans l'air
GB2283816A (en) * 1992-07-13 1995-05-17 Broken Hill Pty Co Ltd Sampling device for airborne particulate or vapour emissions
GB2283816B (en) * 1992-07-13 1996-05-29 Broken Hill Pty Co Ltd Sampling device for airborne particulate and vapour emissions
US5596006A (en) * 1992-10-23 1997-01-21 Bayer Aktiengesellschaft Trisubstituted biphenyls
US5863930A (en) * 1992-10-23 1999-01-26 Bayer Aktiengesellschaft Trisubstituted biphenyls
ES2065268A1 (es) * 1993-05-04 1995-02-01 Univ Madrid Complutense Sensor optico luminiscente.
EP0971225A3 (fr) * 1998-07-09 2000-04-05 HTE GmbH, The high throughput experimentation company Dispositif de détection d'un produit dans l'écoulement d'échappement d'une matière catalytique d'une pluralité de matières catalytiques
US6537500B1 (en) 1998-07-09 2003-03-25 Hte Aktiengesellschaft Process for the detection of a product in the discharge of a catalytic material of a plurality of catalytic materials
US12196727B2 (en) 2019-01-11 2025-01-14 Eth Zurich Device and method for detecting an analyte

Also Published As

Publication number Publication date
EP0485410A1 (fr) 1992-05-20

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