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WO1990012788A3 - ACETALICALLY PROTECTED, ENANTIOMER-PURE α-ARYLALKANE CARBOXYLIC ACIDS, THEIR PRODUCTION AND USE - Google Patents

ACETALICALLY PROTECTED, ENANTIOMER-PURE α-ARYLALKANE CARBOXYLIC ACIDS, THEIR PRODUCTION AND USE Download PDF

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Publication number
WO1990012788A3
WO1990012788A3 PCT/AT1990/000038 AT9000038W WO9012788A3 WO 1990012788 A3 WO1990012788 A3 WO 1990012788A3 AT 9000038 W AT9000038 W AT 9000038W WO 9012788 A3 WO9012788 A3 WO 9012788A3
Authority
WO
WIPO (PCT)
Prior art keywords
acetalically
enantiomer
pure
protected
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/AT1990/000038
Other languages
German (de)
French (fr)
Other versions
WO1990012788A2 (en
Inventor
Christian R Noe
Max Knollmueller
Marion Letschnig
Armin Holzner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of WO1990012788A2 publication Critical patent/WO1990012788A2/en
Publication of WO1990012788A3 publication Critical patent/WO1990012788A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C219/04—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C219/14—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the hydroxy groups esterified by a carboxylic acid having the esterifying carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/08—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Acetalically protected, enantiomer-pure α-arylalkane carboxylic acids of general formula (I), in which A, B, C, and D denote hydrogen or a methyl group in any combination, m and n denote the numbers 0, 1 or 2, where the sum of m and n must be 1 or 2, and in which Ar denotes substituted or unsubstituted aryl or substituted or unsubstituted heteroaryl in any combination and in which R1 denotes branched or unbranched alkyl, preferably low molecular weight alkyl, their production and use.
PCT/AT1990/000038 1989-04-24 1990-04-24 ACETALICALLY PROTECTED, ENANTIOMER-PURE α-ARYLALKANE CARBOXYLIC ACIDS, THEIR PRODUCTION AND USE Ceased WO1990012788A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT96989 1989-04-24
ATA969/89 1989-04-24

Publications (2)

Publication Number Publication Date
WO1990012788A2 WO1990012788A2 (en) 1990-11-01
WO1990012788A3 true WO1990012788A3 (en) 1990-12-13

Family

ID=3503968

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/AT1990/000038 Ceased WO1990012788A2 (en) 1989-04-24 1990-04-24 ACETALICALLY PROTECTED, ENANTIOMER-PURE α-ARYLALKANE CARBOXYLIC ACIDS, THEIR PRODUCTION AND USE

Country Status (2)

Country Link
AU (1) AU5527190A (en)
WO (1) WO1990012788A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT396686B (en) * 1992-04-13 1993-11-25 Christian Dr Noe RAZEMAT SEPARATION REAGENT, METHOD FOR THEIR PRODUCTION AND USE

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH291375A (en) * 1950-12-13 1953-06-15 Hommels S Haematogen Ag Process for the preparation of a-phenylbutyric acid diethylaminoethyl ester.
US3349114A (en) * 1963-05-17 1967-10-24 Hommel Ag Diethylaminoethoxyethyl ester of alpha-phenylbutyric acid and salts thereof
EP0083335A1 (en) * 1981-12-18 1983-07-06 Christian Dipl.-Ing. Dr. Noe Optically active chiral compounds, process for their preparation and use of these compounds in the protection of functional -OH, -SH, -NH- groups, in the separation of racemates, in the preparation of optically active imidoester hydrochlorides and of optically active esters, in the preparation of optically enriched alcohols and in the preparation of optically active compounds by asymmetric induction

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH291375A (en) * 1950-12-13 1953-06-15 Hommels S Haematogen Ag Process for the preparation of a-phenylbutyric acid diethylaminoethyl ester.
US3349114A (en) * 1963-05-17 1967-10-24 Hommel Ag Diethylaminoethoxyethyl ester of alpha-phenylbutyric acid and salts thereof
EP0083335A1 (en) * 1981-12-18 1983-07-06 Christian Dipl.-Ing. Dr. Noe Optically active chiral compounds, process for their preparation and use of these compounds in the protection of functional -OH, -SH, -NH- groups, in the separation of racemates, in the preparation of optically active imidoester hydrochlorides and of optically active esters, in the preparation of optically enriched alcohols and in the preparation of optically active compounds by asymmetric induction

Also Published As

Publication number Publication date
AU5527190A (en) 1990-11-16
WO1990012788A2 (en) 1990-11-01

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