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WO1990006307A3 - Antibacterial quinolone compounds - Google Patents

Antibacterial quinolone compounds

Info

Publication number
WO1990006307A3
WO1990006307A3 PCT/US1989/005213 US8905213W WO9006307A3 WO 1990006307 A3 WO1990006307 A3 WO 1990006307A3 US 8905213 W US8905213 W US 8905213W WO 9006307 A3 WO9006307 A3 WO 9006307A3
Authority
WO
WIPO (PCT)
Prior art keywords
quinolone compounds
antibacterial quinolone
antibacterial
compound
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1989/005213
Other languages
French (fr)
Other versions
WO1990006307A2 (en
Inventor
Ronald B Gammill
Sharon N Bisaha
Joseph M Timko
Thomas M Judge
Michael R Barbachyn
Kyoung S Kim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Priority to KR1019900701694A priority Critical patent/KR910700243A/en
Publication of WO1990006307A2 publication Critical patent/WO1990006307A2/en
Publication of WO1990006307A3 publication Critical patent/WO1990006307A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

A quinolone compound of formula (I) as defined herein having antibacteria properties, pharmaceutical compositions containing the quinoline compound and method for treating bacterial infections in animals including humans.
PCT/US1989/005213 1988-12-06 1989-11-24 Antibacterial quinolone compounds Ceased WO1990006307A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019900701694A KR910700243A (en) 1988-12-06 1989-11-24 Antibacterial Quinolone Compound

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US28060388A 1988-12-06 1988-12-06
US280,603 1988-12-06
US32690789A 1989-03-22 1989-03-22
US326,907 1989-03-22
US33516389A 1989-04-07 1989-04-07
US335,163 1989-04-07
US35501689A 1989-05-22 1989-05-22
US355,016 1989-05-22
US41144989A 1989-09-25 1989-09-25
US411,449 1989-09-25

Publications (2)

Publication Number Publication Date
WO1990006307A2 WO1990006307A2 (en) 1990-06-14
WO1990006307A3 true WO1990006307A3 (en) 1990-07-26

Family

ID=27540650

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1989/005213 Ceased WO1990006307A2 (en) 1988-12-06 1989-11-24 Antibacterial quinolone compounds

Country Status (5)

Country Link
EP (1) EP0447484A1 (en)
JP (1) JPH04502317A (en)
AU (1) AU4743890A (en)
CA (1) CA2004693A1 (en)
WO (1) WO1990006307A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7514451B2 (en) 2003-09-10 2009-04-07 Kyorin Pharmaceutical Co., Ltd. 7-(4-Substituted-3-cyclopropylaminomethyl-1 pyrrolidinyl) quinolonecarboxylic acid derivative

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5137892A (en) * 1990-12-12 1992-08-11 Abbott Laboratories Quinoline, naphthyridine and pyridobenzoxazine derivatives
ES2036136B1 (en) * 1991-10-16 1994-03-01 Inke Sa PROCEDURE FOR THE OBTAINING OF ACID 1- (2,4-DIFLUOROFENIL) -6-FLUORO-7- (3-METHYLPIPERACINIL) -4-OXO-1, 4-DIHIDROQUINOLIN-3-CARBOXILICO AND ITS SALTS.
WO1994025464A1 (en) * 1993-04-24 1994-11-10 Korea Research Institute Of Chemical Technology Novel quinolone carboxylic acid derivatives and process for preparing the same
KR950018003A (en) * 1993-12-09 1995-07-22 스미스클라인 비참 피엘씨 Novel quinolone derivatives and methods for their preparation
EP1313708A1 (en) * 2000-08-29 2003-05-28 Chiron Corporation Quinoline antibacterial compounds and methods of use thereof
US8163769B2 (en) 2002-03-12 2012-04-24 Abbott Laboratories Antibacterial compounds
MXPA05009688A (en) * 2003-03-12 2005-12-05 Abbott Lab Naphthyridine derivatives as antibacterial agents.
EP2970104B1 (en) 2013-03-14 2019-04-24 Zeno Royalties & Milestones, LLC Bicyclic analgesic compounds
CN108947867A (en) 2013-12-12 2018-12-07 卡利拉制药公司 Bicyclic alkyl compound and synthesis
CN113336653A (en) * 2014-03-07 2021-09-03 里科瑞尔姆Ip控股有限责任公司 Propalane derivatives and synthesis
EP3193855B1 (en) 2014-09-17 2021-05-19 Recurium IP Holdings, LLC Bicyclic compounds

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4559342A (en) * 1983-02-25 1985-12-17 Bayer Aktiengesellschaft Quinolone acids and antibacterial agents containing these compounds
US4563448A (en) * 1983-03-12 1986-01-07 Bayer Aktiengesellschaft Bactericidal agents

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4559342A (en) * 1983-02-25 1985-12-17 Bayer Aktiengesellschaft Quinolone acids and antibacterial agents containing these compounds
US4563448A (en) * 1983-03-12 1986-01-07 Bayer Aktiengesellschaft Bactericidal agents

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Chemical Abstracts, Vol. 108, No. 15, 11 April 1988, Columbus, Ohio, US; Narita, Hirokazu et al.: "Preparation of quinolone carboxylic acid derivatives as medical bactericides", abstract 131600s, & JP,A,62 207 258 (11-09-87) *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7514451B2 (en) 2003-09-10 2009-04-07 Kyorin Pharmaceutical Co., Ltd. 7-(4-Substituted-3-cyclopropylaminomethyl-1 pyrrolidinyl) quinolonecarboxylic acid derivative

Also Published As

Publication number Publication date
WO1990006307A2 (en) 1990-06-14
CA2004693A1 (en) 1990-06-06
AU4743890A (en) 1990-06-26
JPH04502317A (en) 1992-04-23
EP0447484A1 (en) 1991-09-25

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