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WO1989006360A1 - Eprouvette pour le traitement automatique de matieres fecales - Google Patents

Eprouvette pour le traitement automatique de matieres fecales Download PDF

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Publication number
WO1989006360A1
WO1989006360A1 PCT/JP1989/000018 JP8900018W WO8906360A1 WO 1989006360 A1 WO1989006360 A1 WO 1989006360A1 JP 8900018 W JP8900018 W JP 8900018W WO 8906360 A1 WO8906360 A1 WO 8906360A1
Authority
WO
WIPO (PCT)
Prior art keywords
container
stool
rod
sample
tip
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP1989/000018
Other languages
English (en)
Japanese (ja)
Inventor
Kazuo Shiraiwa
Kunio Tada
Fumio Yamagata
Tokiharu Noda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Elmex Ltd
Original Assignee
Elmex Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP1988001832U external-priority patent/JPH0633417Y2/ja
Priority claimed from JP1988137567U external-priority patent/JPH0648413Y2/ja
Application filed by Elmex Ltd filed Critical Elmex Ltd
Publication of WO1989006360A1 publication Critical patent/WO1989006360A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/0038—Devices for taking faeces samples; Faecal examination devices

Definitions

  • the present invention generally relates to a sampling device for collecting, transporting, and smearing a culture medium with a desired amount of a sample from an object to be inspected for a microorganism test, and particularly to a stool collection tube for stool inspection.
  • Background technology :
  • a stool collection tube having a stool that collects a samble from a test object for stool inspection, a test tube-like container that stores the stool, and a cab that seals the opening of the container is known.
  • a cotton swab in which the base end of a spoon-shaped member is fixed to a cap and the tip of a rod-shaped member is covered with cotton is typical.
  • sample collection For stool tests for microbial testing, it is important to collect samples from the surface of the test object. It is also desirable to collect an appropriate amount of sample. If it takes time between the sample collection and the microbial test, and if there is a geographical separation between the collection site and the laboratory, enclose a glycerin storage solution or a carrier medium in a test tube, and transfer the sample. It must be immersed or immersed in a storage solution or medium to prevent drying and hardening of the sample, and the growth and death of microorganisms in the sample.
  • the sample is usually applied to the surface of the culture medium in a petri dish using a stool. Smearing of samples may result in isolated colonies on the medium, It is necessary to apply it thinly and dilutely. Shika must not be coated twice and must not damage the medium surface.
  • the worker when applying, the worker removes excess sample from the stool and then applies the shampoo.However, even in such a case, the medium where the stool was first in contact with the surface of the medium was concentrated. The concentration of the smear becomes thinner as the stool moves. In order to promote this tendency, it is common practice to gradually increase the coating speed. Its coating speed must be quite fast. If the smear is inappropriate, isolated colonies will not be obtained and proper testing will not be possible. Therefore, the painting work requires ripening.
  • a spoon-shaped one is often used as a stool, and if the sample is collected by a non-specialist, the sample is collected correctly from the surface of the inspection object.
  • the sample is collected correctly from the surface of the inspection object.
  • the test object was liquid, the sample was washed off from the spoon with the preservation solution or the carrier medium, and an appropriate amount of the sample could not be held on the spoon surface.
  • the sample is extremely hard, the sample will not be sufficiently buried in the culture medium, so that the sample will not only have problems such as drying, hardening, microbial growth and death, but also on the surface of the stool body. An appropriate amount of sample could not be deposited.
  • the spread operation is performed on the convex (rear) surface of the spoon. If the spoon is set up too much to apply a fine spread, the medium surface will be damaged and proper inspection will be impossible.
  • test object Even when using a cotton swab as a stool, it is often the case that the test object is not correctly collected from the surface of the test object, and if the test object is extremely hard, an appropriate amount of sample is used. It was difficult to collect the swabs, and if they were forced to do so, the swabs were damaged and widened. In addition, the cotton swab had high water retention and was soft, so it was difficult to apply it thinly and dilutely. The excess sample had to be wiped off as described above.
  • the stool tube may vibrate, lie down, or turn upside down during transport of the stool tube, causing condensed water or leachate from the stock solution or medium containing the sample. It adheres to the inside of the stool and cab of the stool and stains the inspector's hand when applying or removing the cap of the stool tube at the inspection organization, or on the culture medium. It was dripping.
  • This problem is solved with the attention and attention of a skilled expert. It is difficult for a machine to make a situation judgment equivalent to the consideration of a skilled expert. Also, it is desirable to apply the paint easily without any special consideration when applying the paint by the application method.
  • the stool collection body is an elongated solid rod, an elongated hollow rod, or a combination of these and a sheath, and a region close to the tip thereof.
  • the surface is taken as a rough surface.
  • the stool is made of only a solid rod-shaped body, and the surface of the region near the front end is roughened.
  • the stool is composed of an elongated sheath and an elongated rod movably accommodated in the longitudinal direction of the sheath, and the distal end of the sheath An opening is provided in the portion, and the opening is pressed to open so that the rod-shaped body can protrude.
  • the surface of the region close to the tip of the above-mentioned sheath and the rod or the rod-shaped body is roughened.
  • the toilet body includes a hollow elongated rod-shaped or bag-shaped body, and the surface of the distal end region of the hollow rod-shaped or bag-shaped body is roughened.
  • Means is provided for stretching, so that when the rough surface is stretched, the sample captured in the concave portion of the rough surface is exposed on the surface of the stretched rod or bag.
  • Methods for roughening the surface of the tip of a round bar include forming one or more uneven strips on the surface, forming mesh-like unevenness, and forming a matte (grind glass surface).
  • a matte grinding glass surface
  • the stool is composed of a sheath and an elongated rod movably provided in the longitudinal direction, when the sheath or the rod is protruded, the excess amount attached to the surface of the rod Pururu helps the sample captured by the sheath to adhere to the rod in an appropriate amount.
  • the stool When the stool is made of a hollow rod-shaped or bag-like body made of hollow fiber and provided with a means for extending the rough surface, the specimen captured by the concave portion of the rough surface is It is exposed on the smoothed surface, so that an appropriate amount of coating is possible.
  • a simple method such as applying a fluid pressure into the hollow shell or stretching with a push rod is simple, but other methods are also acceptable.
  • the hollow rod-shaped body or the bag-shaped body may have at least a degree of rigidity at least with respect to the external force extending in the longitudinal axis direction, and the rough surface may be stretched.
  • the upper end of the container is cut obliquely with respect to the longitudinal axis.
  • the area of the opening portion of the container increases, and when the toilet body is inserted into the container, the sample is less likely to adhere to the opening portion of the container by mistake, and the size of the feces collection tube is reduced.
  • for inspection laboratories by holding the stool collection tube in an upright position for a while, the liquid adhering to the handle and cap of the stool is inclined and opened. It can flow down along the part and be collected in a container. Desirably, the above-described effect can be further enhanced by chamfering the inner surface of the container of the opening part obliquely from above to below.
  • the outer peripheral edge of the obliquely cut upper end of the container bulges outward in a headband shape that closely adheres to the inner surface of the cab. . According to this, the above-mentioned collection chrysanthemum is large.
  • a toilet body is fixed to a central portion of the inner surface of the top plate of the cap, and an opening portion of the container is provided in a region close to the fixing portion. And / or an elastic member is hermetically pressed against the inner surface. Accordingly, it is possible to prevent the liquid containing the sample from adhering to the outer surface of the container and the inner surface of the cap.
  • the stool is fixed to the central portion of the inner surface of the top of the cap or is formed integrally, and the area close to the fixing portion is provided.
  • a sealing member made of an elastic material which is hermetically pressed against the opening portion of the container and the Z or the inner surface, but in this embodiment, the upper end of the container is opposed to the longitudinal axis of the container. I was cut diagonally.
  • the lower surface of the sealing member in the embodiment just described is an inclined surface projecting downward about the longitudinal axis of the toilet body. Accordingly, the sample-containing liquid attached to the sealing member easily flows down along a part of the toilet body. This feature is particularly useful for mechanized smearing operations. This is because as many samples are retained in the stool and flow down.
  • FIG. 1 is a cross-sectional view schematically illustrating the structure of a stool tube of the present invention
  • FIGS. 2a-d are partial cross-sectional views showing some embodiments of the present invention with a feces body consisting of an elongated solid
  • FIGS. 3a to 3e are partial cross-sectional views showing some embodiments of the present invention with a stool made of a rod and a sheath.
  • FIG. 4 is a schematic side view illustrating a case where a wiping membrane is provided on the machine side instead of providing the sheath body on the toilet body,
  • FIG. 5 is a cross-sectional view showing an example of a structure for moving the rod-shaped body and the sheath body relatively in the longitudinal direction
  • FIGS. 6a to 6c are partial cross-sectional views showing some embodiments of the present invention, which have an elongated rod-shaped body, a bag-shaped body or a Z-shaped body and a push rod or a cylinder-shaped stool, which are hollow and hollow.
  • FIG. 7 is a cross-sectional view showing an embodiment of the present invention having a desired structure of a container and a cab of a stool collection tube,
  • FIG. 8 is a partial sectional view showing a modification of the container
  • FIG. 9 is a partial cross-sectional view showing an embodiment of a fecal collection tube having a sealing member
  • FIG. 10 is a partial sectional view showing a modification of the embodiment of FIG. 9,
  • FIG. 11 is a partial cross-sectional view showing a modification of the embodiment of FIG. BEST MODE FOR CARRYING OUT THE INVENTION
  • FIG. 1 is a cross-sectional view schematically illustrating the configuration of the feces collection tube of the present invention.
  • the container 10 and the cap 20 are shown as being screwed together to seal the opening of the container.
  • the detachable structure of the container 10 and the cap 20 can be attached and detached by mechanization and manually, and if it can seal the container, it can be made of a large-sized structure.
  • a click-stop structure with complementary concave and convex parts is provided at the press-fit portion between the container and the cap.
  • a screw-in cab that is similar to a bayonet mount.
  • Various types of such engaging structures and sealing structures are known, and these structures can be applied as long as they conform to the present invention.
  • the toilet body 30 and the cap 20 may be formed integrally, or after being formed separately, the base end 31 c of the toilet body and the cap 20 are fixed to each other. Good to combine.
  • the surface of the region near the distal end of the toilet body 30 is roughened.
  • the surface part used for the smear of the stool should not necessarily be rough, but should be as small as possible, and should be a small curved surface that is as thin and dilute as possible. Is desirable.
  • FIGS. 2a to 2d show some examples in which the stool body 30 is composed of only an elongated and solid rod 31.
  • FIG. 2 the base end portion of the rod-shaped pair 31 is omitted, and the tip end portion and the culture medium C in the petri dish S are shown.
  • the rod 31 is a tapered round bar, and the entire surface of the tip 31a and the area 31b close to the tip is a matte rough surface.
  • the sticking operation can be performed by inclining the rod-shaped body in a direction perpendicular or perpendicular to the surface of the culture medium C.
  • the portion 3 1b of the rod 31 in the vicinity of the tip 31a is swollen, forming a mesh-like rough surface and increasing the surface area. .
  • the minimum required sample can be collected, and the rods 31 are roughened when immersed in the preservative solution, the carrier culture medium, buried, and withdrawn from them. It is possible to increase the amount of samble held on the surface. It also has the effect of reducing the speed at which the sample moves on the surface of the stool during smearing.
  • the tip 31 a of the rod 31 is tapered, and the surface of the tip 31 a is shown as being smooth.
  • This embodiment has substantially the same advantages as the embodiment of FIG. 2b, and also applies a sample to the culture medium C while the rod 31 is inclined with respect to the surface of the culture medium C in the illustrated direction. Suitable for splashing.
  • FIG. 2d different types (for example, as shown in FIG. 2) of the surface of one side 3 1 b ′ of the region close to the tip 31 a of the rod 31 and the other side 3 1 b ′ are used.
  • the rough surface on one side shall be a rough surface suitable for collecting the hardness test object, and the rough surface on the other side shall be liquid or soft (a rough surface suitable for collecting the test object). It has been formed.
  • a means for indicating the side on which the sample is attached can be provided on the cab 20.
  • Such a display means can be provided in various ways, such as putting an asymmetrical identification cab on the cab with respect to the longitudinal axis, attaching a coloring mark for identification, attaching a magnetic mark, and the like.
  • the rod-shaped body 31 may be formed integrally with the cap 20, they may be formed as separate parts, and the base end 31 c of the rod-shaped body may be retrofitted to the cab 20. .
  • the body 30 When the body 30 is formed symmetrically with respect to the longitudinal axis (for example, in FIGS. 2a and 2b), the body 30 is fixed to the center of the cap 20, and When the body is handled by the machine, the direction of the stool is lost and there is no danger of damaging the culture medium when smeared.
  • the stool body 30 When the stool body 30 is formed non-axisymmetrically with respect to the longitudinal axis (for example, Fig. 2c), select the direction in which the part to be brought into contact with the culture medium C contacts the culture medium surface correctly. It is necessary to make the machine hold the toilet body 30. For the selection of the gripping direction, the method described with reference to FIG. 2d and various other methods known in mechanical technology can be used.
  • the rough surface formed on the surface of the region 3 1 b close to the tip 31 a of the rod 31 has one or more uneven stripes, mesh-like unevenness, orientation, length and shape. ⁇ ⁇ ⁇ It can be formed to a desired depth along wrinkles or satin finish. More specifically, the uneven stripes are one or more uneven stripes oriented parallel to the longitudinal axis of the rod 31, one or more uneven stripes oriented in a direction perpendicular to the longitudinal axis of the round bar 30, In other words, i or more ring-shaped uneven strips provided parallel to the surface 31b of the end 31a and / or the area near the end 31a of the sacrifice 31 and the longitudinal axis of the rod 31 It is also acceptable to use one or more uneven stripes or the like oriented in the direction inclined to the surface.
  • the ridges and grooves have an appropriate pitch angle and pitch with respect to the longitudinal axis of the rod 31.
  • One or more ridges formed in a spiral shape with intervals may be used, or a plurality of intermittent ridges orientated in a direction inclined with respect to the longitudinal axis of the rod 31. Very good.
  • rods 31 are made of, for example, synthetic resin, synthetic rubber, glass, and ceramic.
  • the spur is preferably made of a material such as a metal, and more preferably
  • 3 1 is made of colorless and transparent, colored and transparent, and blue is made of a slightly light-colored white material, and the transparency or lightness is determined by optical detection means. It is good to be able to judge automatically. If the sample itself does not have a color, a colorant can be mixed into the preservation solution or the medium to facilitate determination of the amount or concentration of the sample on the stool by the optical detection means.
  • the contact pressure between the rod 31 and the surface of the culture medium C may be at least a part of the rod 31 or the joint between the cab 20 and the rod 31. Since it is made of a flexible material, it is not necessary to adjust it strictly.
  • the contact pressure between the rod 31 and the surface of the culture medium C may utilize the weight of the toilet body 30 and a part of the machine, and an elastic biasing means using a pneumatic spring or the like may be used. It can be adjusted by various means, such as using it.
  • the feces body 30 includes a sheath 32 and an elongated rod-shaped body 31 housed movably in the longitudinal direction of the sheath 32.
  • FIGS. 3a to 3e show cross-sectional views of some embodiments having such a structure.
  • the sheath body 32 accommodates a rod 31 similar to the embodiment shown in FIG. 2A so as to be movable in the longitudinal direction. It is assumed that the surface 2a and the region 32b adjacent thereto have a rough surface. Tip 3 1a of rod 3I and Alternatively, a rough surface may be formed in the region 31b adjacent thereto, and it is not necessary that the surface be formed. In this example, when the sample was collected, the rough surface formed on the tip of the sheath 32a and the area 32b adjacent to the tip of the sheath 32a The sample is captured as well as the rough surface formed in the part 31a and the area 31b adjacent thereto.
  • the sheath 32 gradually becomes thinner as it approaches the distal end 32a, and the distal end 32a has an opening 32d that allows the rod 31 to protrude.
  • the sheath 32 is formed of a rubber-like elastic material, and the opening 32 d of the tip 32 a is almost in close contact with and tightly closed.
  • a means (described later) for projecting the rod 31 from the tip 3 2 a of the sheath 32 is provided.
  • the sheath 3 2 The sample adhering to the rough surface moves to the tip of the rod 31 and the surface of the region close to the tip.
  • the material forming the sheath 32 is not limited to the rubber-like elastic material, and may be formed of any material as long as the rod 31 can protrude from the opening 32 d.
  • the sheath body 32 is the same as the embodiment of FIG. 3a except that the region 32b adjacent to the distal end 32a is thickened and swells. Same as. The rough surface of the swollen region 32b has the same effect as described with reference to FIG. 2b.
  • a rod 31 similar to the embodiment of FIG. 2b is housed in a sheath 32 so as to be movable in the longitudinal direction.
  • a rough surface is formed on the surface of the tip 32 a of the sheath 32 and the region 32 b adjacent thereto.
  • the region 3 1b adjacent to the tip 3 1a of the rod 31 has a satin-like rough surface.
  • the rod 3 3 When 1 is protruded, the speed at which the sample is transferred from the rough surface of the sheath 32 to the tip 31 a of the rod 31 decreases.
  • the other points are the same as those of the embodiment in FIGS. 3a and 3b.
  • the sheath 32 has been described as being formed of an elastic material in the examples of FIGS. 3a to 3c, the sheath 32 has a tip 3 2a and a region 3 2b adjacent to the tip 3a.
  • the sheath 32 may be flexible, for example, by giving a radial crack or splitting it radially with a small mosquito in advance. It can be formed of a conductive material. In this case, the transfer of the sample from the sheath 32 to the rod 31 may be uneven. This can be solved, for example, by rotating the rod 31 and the sheath 32 relatively with respect to the longitudinal axis.
  • a rough surface is provided on the surface of the rod 31, and at the time of stool, the rod 31 is protruded from the opening of the sheath 32 and collected.
  • the rod 31 is immersed or buried in a storage solution or a carrier medium as it is, and the rod 31 is stored in the sheath 32 prior to coating, and then the rod 31 is opened again. You can make it d. In this case, it is not always necessary to form a rough surface on the surface of the sheath 32.
  • the sheath 32 and the rod 31 are the same as in the embodiment of FIG. 3a, and the tip 31a of the rod 31 A slight gap G is provided between the tip of the sheath 32 and the inner surface of the 2a, and the tip 3 of the sheath 32 is formed.
  • a plurality of openings 32e are provided in a region 32b close to 2a. At the time of collection, rub the opening 32 e against the surface of the object to be inspected, and actively collect the sample in the gap G ⁇ . At this time, the edge at the opening 32 e is advantageous for removing the sample.
  • the storage solution or the liquid component of the carrier medium is introduced into the gap G from the opening 32e.
  • Rod 3 1 is a sheath
  • the sample in the gap G is a rod when protruding
  • the excess sample is attached to the surface of the tip 31 a of the body 31 and the area 31 b adjacent thereto, and excess sample is wiped off by opening 32 d.
  • the rod 31 is protruded from the opening 32 d of the sheath 32, there is a possibility that excess sample is discharged from the opening 32e. Therefore, it is only necessary to protrude the rod 31 from the sheath 32 on an appropriate filth reservoir on the outside of the chamber S to collect the excess samble into the trash. It is also recommended that the reservoir be disinfected and washed at least periodically.
  • the opening 32d at the tip of the sheath 32 becomes a relatively large opening
  • the tip 31a of the rod 31 becomes the opening 32d.
  • Slightly projecting from A rough surface is formed on the surface of the distal end portion 32 a of the sheath 32 and the region 32 b adjacent thereto.
  • the protruding tip 31a of the rod 31 has a smooth surface.
  • the sample is collected by rubbing the rough surface of the tip 32a of the sheath 32 and the area 32b adjacent thereto on the surface of the inspection object. At this time, the sample also adheres to the tip 31a of the rod 31.
  • the tip 31a of the rod 31 is considered as a smooth surface.
  • the tip 31a of the rod 31 protruding from the tip 3 2a of the sheath 32 is the same as the tip 3 2a of the sheath 32. It is also good to cut the rod on a flat surface and make the tip of the rod like a truncated cone.
  • the rod-shaped body 31 is housed in the sheath 32 and is wiped with the opening of the container 10.
  • an excess sample is shaken off by applying an impact to the stool 30, and after that, an appropriate concentration is applied by performing a spreading operation.
  • the spray is applied on the arc portion where the top surface of the truncated cone of the rod 31 and the slope meet, the surface in contact with the culture medium surface becomes small.
  • the opening 32d at the tip of the sheath 32 need not be closed, and may be an opening having a small cross-sectional area. In this case, there is an advantage that the sample can be captured in the opening 32d; however, on the other hand, the sample may be excessively attached to the tip of the rod-shaped body 31, so that the To remove excess sample. Excessive sambre removal, for example, can impact the stool 30 on a basin and can be shaken off.
  • the stool tube of the present invention is taken out, and the membrane M of the elastic material shown in FIG. 4 is fixed below the rod 31 on the machine side.
  • a small opening M 1 may be provided at a position slightly deviated from the portion where the rod 31 abuts on the film M.
  • the tip 31 a of the rod 31 first contacts the elastic membrane M to wipe off the excess sample at the tip, and when the rod 31 moves downward, the tip 31 a opens.
  • the excess sample can be wiped from the surface of the region 31 b adjacent to the tip of the rod 31.
  • the membrane M is replaced every time. It is also good to move the rod 31 downward while rotating it around its longitudinal axis.
  • FIG. 5 shows an example of a cross section of a key structure for relatively moving the rod 31 and the sheath 32 in cross section.
  • the relationship between the cap 20 and the test tube 10 is shown as a screw connection between a male screw formed on the outer surface of the open part of the test tube 10 and a female screw formed on the inner surface of the cap 20.
  • the base end 31 c of the rod 31 is firmly fixed along the mounting structure 21 formed on the cap 20.
  • a ring-shaped ridge 32 f protruding inward is formed on the side of the rod 31 a single ring-shaped recess 3 is formed. 1d are formed and they mate with each other.
  • a ring-shaped flange member 32 g protruding in the radial direction is formed on the trunk of the sheath body 32.
  • the sample is attached to the rough surface of the tip of the sheath 32 from the surface of the inspection object.
  • the rod 31 and the sheath 32 are left as they are, and the tip of the sheath 32a and the area close to it in the preservation solution or test solution in the test tube 10 or the carrier culture medium. 3 2b is immersed or buried.
  • the cap 20 is removed from the test tube 10 by hand or machine, and the cap body 20 and the cab 20 are relatively moved in a direction to approach each other. By moving it, the tip 31a of the rod is protruded from the opening 32d of the sheath. It is clear that the extrusion structure shown in FIG. 4 can be applied to any of the embodiments shown in FIGS.
  • Means for relatively moving the sheath body 32 and the rod body 31 in the longitudinal direction are known as various structures in mechanical technology, as long as all of them are compatible with the present invention. Available.
  • the stool body 30 is a hollow elongate rod-shaped body 31 or bag-shaped body 33 or Z and a sacrifice 34 or cylindrical body 35. You.
  • the hollow The rod-shaped body 31 or the bag-shaped body 33 is drawn with a thick solid line with its thickness reduced.
  • the rod 31 is made of a deformable forest material when the fluid pressure in the interior 31 h increases in the hollow structure.
  • the tip 31 a and the region 31 b adjacent to the tip are rough surfaces.
  • the hollow rod-shaped body 31 When fluid pressure is applied to the inside of the cavity 31 h of the rod 31, the rough surface formed on the surface of the tip 31 a of the rod 31 and the area 31 adjacent thereto (uneven stripes, meshes) (Wrinkles, wrinkles, etc.) are stretched, and the sample trapped in those recesses is exposed on the stretched surface of the rod.
  • the hollow rod-shaped body 31 normally needs to have a self-shape retaining force to the extent necessary for the sampling operation. In some cases, deformation (stretching) can be facilitated by introducing heated pressurized fluid into the cavity.
  • the hollow bag 33 is formed of an elastic material such as rubber.
  • the surface of the tip 33a or the region 33b adjacent to the tip of the bag 33 is rough.
  • a flange 33 g protruding in the radial direction is formed on the body of the bag 33.
  • a push rod 34 is inserted into the cavity of the bag 3.3, so that the base end (upper part in the figure) of the push rod 34 and the flange 33g of the bag are alternated. When moving in a direction approaching the surface, the rough surface is stretched and the sample captured by the concave portion of the rough surface is exposed.
  • a pressurized fluid is introduced between the push rod 34 and the bag 33 instead of relatively moving the push rod 34 and the bag 33 to make the rough surface May be stretched.
  • a groove or a pipe for guiding the pressurized fluid can be formed in the push rod 34.
  • the toilet body 30 is shown as comprising a bag-like body 33 and a cylindrical support 35.
  • the tip 3 3 a of the bag 3 3 and the area 3 3 b adjacent to it have a rough surface, and a part of the tip of the bag 3 3 is inverted to form the cylindrical support 35. It is housed in the opening at the tip 35 a.
  • the bag-like body 33 is actually in close contact with the side surface of the cylindrical support 35, but is drawn with a space between them for convenience of explanation.
  • the sample is caught in the tip of the bag 33 inverted and stored in the opening 35a, and the tip of the bag 33 is pushed out by fluid pressure or a push rod (not shown).
  • the excess sample is removed and an appropriate amount of the sample is exposed on the stretched surface of the bladder.
  • the pressurized fluid may be air, water, or the like, and the fluid may be a hollow rod 31 or a bag-like body 33 with a cavity 31 h or 33 h sealed and a cavity.
  • the internal pressure may be increased by sandwiching the base end manually or with a machine, and the base end of the rod 31 or the bag 33 may be opened, and the released end may be inserted into the machine. It is good to connect to the fluid supply line and introduce the pressurized fluid into the cavity 31 h or 33 h.
  • Such a structure itself is known in mechanical technology, and will not be described in detail.
  • the cab opening does not necessarily need to be sealed, but if sealing is desired.
  • the opening of the cap can be fitted with a suitable hermetic stopper, for example a push fit.
  • the shapes of the tips 31 a and 33 a of the hollow rod-shaped body or the bag-shaped body are drawn in a hemispherical shape.
  • Fig. 2 can be drawn in a simple shape as shown in Figs.
  • the wedge of the opening 32e may be made to protrude from the outer surface of the sheath 32 to facilitate the collection of the inspection object.
  • a taper is applied to the tip of the tubular support 35, and the taper is opened at the tip of the tubular support. B can be cut at an angle with respect to the longitudinal axis to make it easier to collect the sumble at the time of collection.
  • the cylindrical support 35 and the bag-shaped body 33 may be relatively moved in the same manner as in the embodiment of FIG. 6b, and the rough surface of the bag-shaped body 33 may be stretched.
  • FIG. 7 is a cross-sectional view showing a container 10, a cap, 20 and a stool 30 according to the most basic embodiment of the stool collection tube of the present invention.
  • the cap 20 is provided with a ring-shaped protruding ridge 22 protruding inward at the lower end portion or the opening portion 21, and the corresponding portion on the outer surface of the container 10 has a corresponding concave portion. 13 is formed. It is shown that a cylindrical projection 23 is provided on the inner surface of the top wall of the cap.
  • the toilet body 30 has a coupling end 36 fitted into the cylindrical projection 23 of the cap at the upper end, a flange 37 contacting the lower surface of the cylindrical projection 23, and a flange. It has a handle portion 38 extending downward from the portion, and a sampling portion 39 having a waterdrop-like side shape at its lower end. The surface of the sampling part 39 is roughened, and the sampling is facilitated.
  • the upper end or the opening 11 of the container 10 is cut obliquely with respect to the longitudinal axis of the container 10.
  • the area of the opening portion is increased, and the sample is less likely to be attached to the opening portion of the container by mistake when the stool is introduced into the container.
  • the collection tube vertically for a while, The liquid adhering to the opening and the cap flows down along the inclined surface of the opening and can be collected in the container.
  • a chamfered portion 12 on the inner surface adjacent to the opening 11 of the container aids in the recovery of the liquid containing the sample.
  • the plurality of ridges 17 formed in a headband shape in the middle of the container 10 are used to prevent slippage when the cap 20 is pulled out of the container 10.
  • FIG. 8 is a sectional view of a stool collection tube according to another embodiment of the present invention.
  • the outer peripheral edge of the obliquely cut upper end 11 of the container 10 bulges outward in the shape of a headband that closely adheres to the inner surface of the side wall of the cab 20.
  • the swelling portion 14 prevents the sample from entering between the outer surface of the container 10 and the inner surface 24 of the side wall of the cap.
  • the inner side surface of the container 10 adjacent to the opening is beveled obliquely from above to below. In other respects, it is the same as the embodiment of FIG. 7, and the same parts are indicated by the same reference numerals.
  • FIG. 9 is a sectional view of a stool collection tube according to still another embodiment.
  • the toilet body 30 is coupled to the center of the inner surface of the top of the cap 20, and the inner surface of the container 10 is located in a region close to the coupling portion.
  • a sealing member 40 made of a resilient material that is hermetically pressed against 15 is provided.
  • the upper end 11 of the container 10 is cut obliquely with respect to the longitudinal axis.
  • the pressure contact between the inner surface 15 of the container 10 and the sealing member 40 prevents the liquid containing the sample from adhering to the outer surface 16 of the side wall of the container 10 and the inner surface 24 of the side wall of the cap 20. can do.
  • the lower surface of the sealing member 40 is an inclined surface 41 projecting downward about the longitudinal axis of the toilet body.
  • a sealing member 40 When a sealing member 40 is provided, it is necessary to cut the opening 11 of the container 10 obliquely to the longitudinal axis of the container in order to allow the sample to flow down into the container 10. I don't need it. However, if the sealing member is incomplete, the upper end of the container should be taken into account in consideration of the emergency, and in addition to the common use of the feces collection tube for the application method and the mechanization method. It is desirable to cut diagonally.
  • FIG. 10 is a sectional view of a stool collection tube according to still another embodiment of the present invention.
  • the toilet body 30 is fixed to the center of the side surface of the top plate of the cap 20.
  • Sealing member 4 made of an elastic material that is air-tightly press-fitted (not fitted) to the peripheral edge of the obliquely cut opening 11 of the container 10 in the area close to the fixed end 36.
  • the lower surface of 0 is an inclined surface 41 projecting downward around the longitudinal axis of the toilet body.
  • the upper part of the sealing member 40 is extended upward in a cylindrical shape 42.
  • the side surface of the flange 37 is reduced in diameter from the top to the bottom and inclined so that the angle between the inclined surface and the upper surface of the flange 37 is smaller.
  • the projection 43 protrudes outside the cylindrical projection 23.
  • the cylindrical portion 42 extending above the sealing member 40 is covered over the flange 37 and the cylindrical projection 23.
  • FIG. 11 is a sectional view of a stool collection tube according to still another embodiment of the present invention.
  • the toilet body 30 is shown as being formed integrally with the cap 20.
  • the upper part of the sealing member 40 extends upward in a cylindrical shape. Also in this embodiment, a sharp projecting portion 43 projecting outward is formed on the side surface of the fixed portion of the toilet body 30.
  • the sealing member 40 is inserted from the side of the collection part 39 at the lower end of the toilet body 30. In this case, if the elasticity of the sealing member 40 is large, the sealing member 40 can be brought into close contact with the handle portion of the toilet body according to the restoration force. If the elasticity of the sealing member 40 is small, a gap 44 is formed between the handle portion 38 of the stool and the sealing member 40 as shown in the figure. This can be effectively used as a means for holding the filter sample on the stool 30.
  • the opening of the container when the opening of the container is cut diagonally, if the cross-sectional shape perpendicular to the longitudinal axis of the container is a perfect circle, However, the open surface has an elliptical shape, and the short axis of the ellipse is not enlarged at all.
  • the cross-sectional shape perpendicular to the longitudinal axis of the container is ⁇ ⁇ elongated ⁇ oval, ⁇ ⁇ flattened
  • the upper end of the container is cut diagonally on a plane that includes the long axis or the longest long side of the cross-section and that intersects the long axis of the container. They can be expanded together.
  • the present invention enables the downsizing of the stool tube by improving the structure of the stool and the structure of the container and the cap of the stool tube, and enables the collection of an appropriate amount of sample from the test object. It makes it possible to collect samples from a large number of test objects and apply them to a large amount of culture medium, because it makes it easier to work, makes it possible to mechanize the painting work, improves work efficiency and improves the working environment for laboratories. It is particularly suitable for use in various testing laboratories.

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

Une éprouvette pour matières fécales ayant une structure nouvelle comprend un réservoir de solution ou de milieu de conservation, un bouchon de fermeture du réservoir et un élément échantillonneur de matières fécales fixé sur le bouchon. L'élément échantillonneur de matières fécales a une forme allongée similaire à une tige ou à un sac. La surface de la zone proche de son extrémité est rugueuse et peut être frottée contre un objet à des fins d'échantillonnage. Etant donné que l'extrémité de l'élément d'échantillonnage de matières fécales est conique, on peut appliquer une couche mince et étroite de l'échantillon sur le milieu. Lorsque cette couche est automatiquement appliquée par rotation de l'élément échantillonneur autour de son axe longitudinal, elle peut s'obtenir sans interruptions. On peut optimiser la quantité d'échantillon et la concentration de la couche appliquée sur le milieu en attachant un manchon à l'élément similaire à une tige ou à un sac, et on peut en outre optimiser la quantité déposée d'échantillon au moyen d'un élément qui rend plus lisse la surface rugueuse de l'élément échantillonneur. Si l'ouverture du réservoir est chanfreinée par rapport à l'axe longitudinal du réservoir sa superficie est accrue et on peut insérer plus facilement dans le réservoir l'échantillon de matières fécales. En même temps, on peut récupérer dans le réservoir l'échantillon collé au bouchon et réduire les dimensions de l'éprouvette. Une partie élargie est agencée sur la surface latérale extérieure de l'ouverture du réservoir, ou un organe d'étanchéité en matériau souple est agencé à l'intérieur du bouchon, l'organe d'étanchéité ayant une surface conique saillante vers le bas dont le centre est l'axe longitudinal de l'élément échantillonneur.
PCT/JP1989/000018 1988-01-11 1989-01-10 Eprouvette pour le traitement automatique de matieres fecales Ceased WO1989006360A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP1988001832U JPH0633417Y2 (ja) 1988-01-11 1988-01-11 機械化処理に適した採便管
JP63/1832U 1988-01-11
JP1988137567U JPH0648413Y2 (ja) 1988-10-21 1988-10-21 採便管の構造
JP63/137567U 1988-10-21

Publications (1)

Publication Number Publication Date
WO1989006360A1 true WO1989006360A1 (fr) 1989-07-13

Family

ID=26335118

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP1989/000018 Ceased WO1989006360A1 (fr) 1988-01-11 1989-01-10 Eprouvette pour le traitement automatique de matieres fecales

Country Status (1)

Country Link
WO (1) WO1989006360A1 (fr)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0638803A4 (fr) * 1992-12-18 1996-05-15 Eiken Chemical Recipient transportable pour prelevement de selles.
CN104122113A (zh) * 2014-07-17 2014-10-29 河南科技大学第一附属医院 一种普通标本留取容器
EP3622894A1 (fr) * 2013-12-12 2020-03-18 Case Western Reserve University Dispositif de collecte d'un échantillon biologique
US20200390425A1 (en) * 2017-11-28 2020-12-17 V-Veil-Up Pharma Ltd. Self sampling universal kit, methods and use
US12262879B2 (en) 2020-06-16 2025-04-01 Case Western Reserve University Device for biological cell collection and method of use

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS485791U (fr) * 1971-03-02 1973-01-23
JPS5653445A (en) * 1979-07-09 1981-05-13 Levine Robert A Feces sampler
US4273741A (en) * 1979-07-09 1981-06-16 Levine Robert A Device for obtaining stool samples

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS485791U (fr) * 1971-03-02 1973-01-23
JPS5653445A (en) * 1979-07-09 1981-05-13 Levine Robert A Feces sampler
US4273741A (en) * 1979-07-09 1981-06-16 Levine Robert A Device for obtaining stool samples

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0638803A4 (fr) * 1992-12-18 1996-05-15 Eiken Chemical Recipient transportable pour prelevement de selles.
EP3622894A1 (fr) * 2013-12-12 2020-03-18 Case Western Reserve University Dispositif de collecte d'un échantillon biologique
US10660621B2 (en) 2013-12-12 2020-05-26 Case Western Reserve University Device for collecting a biological sample
US12376837B2 (en) 2013-12-12 2025-08-05 Case Western Reserve University Device for collecting a biological sample
CN104122113A (zh) * 2014-07-17 2014-10-29 河南科技大学第一附属医院 一种普通标本留取容器
US20200390425A1 (en) * 2017-11-28 2020-12-17 V-Veil-Up Pharma Ltd. Self sampling universal kit, methods and use
US12262879B2 (en) 2020-06-16 2025-04-01 Case Western Reserve University Device for biological cell collection and method of use

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