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WO1988000191A3 - Derives de guaiazulenes et leurs utilisations - Google Patents

Derives de guaiazulenes et leurs utilisations Download PDF

Info

Publication number
WO1988000191A3
WO1988000191A3 PCT/US1987/001563 US8701563W WO8800191A3 WO 1988000191 A3 WO1988000191 A3 WO 1988000191A3 US 8701563 W US8701563 W US 8701563W WO 8800191 A3 WO8800191 A3 WO 8800191A3
Authority
WO
WIPO (PCT)
Prior art keywords
compositions
guaiazulenes
derivatives
methods
guaiazulene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1987/001563
Other languages
English (en)
Other versions
WO1988000191A2 (fr
Inventor
Tatsuo Higa
Shinichi Sakemi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Harbor Branch Oceanographic Institute Foundation Inc
Original Assignee
Harbor Branch Oceanographic Institution Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harbor Branch Oceanographic Institution Inc filed Critical Harbor Branch Oceanographic Institution Inc
Publication of WO1988000191A2 publication Critical patent/WO1988000191A2/fr
Publication of WO1988000191A3 publication Critical patent/WO1988000191A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/06—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings
    • A01N43/12—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings condensed with a carbocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Plant Pathology (AREA)
  • Environmental Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)

Abstract

De nouvelles compositions de guaïazulène sont utiles comme compositions antitumorales, immunomodulatrices et fongicides; un procédé permet de produire des compositions de guaïazulène et un procédé d'immunomodulation et d'inhibition de tumeurs et de champignons utilise ces compositions de guaïazulène. Ces compositions sont en particulier dérivées des gorgones marines de l'espèce Acalycigorgia.
PCT/US1987/001563 1986-06-26 1987-06-25 Derives de guaiazulenes et leurs utilisations Ceased WO1988000191A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US879,080 1986-06-26
US06/879,080 US4755529A (en) 1986-06-26 1986-06-26 Guaiazulene derivatives and their methods of use

Publications (2)

Publication Number Publication Date
WO1988000191A2 WO1988000191A2 (fr) 1988-01-14
WO1988000191A3 true WO1988000191A3 (fr) 1988-04-07

Family

ID=25373402

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1987/001563 Ceased WO1988000191A2 (fr) 1986-06-26 1987-06-25 Derives de guaiazulenes et leurs utilisations

Country Status (4)

Country Link
US (1) US4755529A (fr)
EP (1) EP0272310A1 (fr)
JP (1) JPH01500516A (fr)
WO (1) WO1988000191A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5235076A (en) * 1991-05-28 1993-08-10 University Of Hawaii Azulenic retinoid compounds, compositions and methods
US5696105A (en) * 1996-03-14 1997-12-09 Hackler; Walter A. Antifungal nail composition
KR100350891B1 (ko) * 2000-03-08 2002-09-05 한국해양연구원 아칼리시제니올리드 ｃ, ｄ, ｅ 및 ｆ
CN104003959B (zh) * 2014-06-11 2016-05-25 四川大学 愈创兰烃薁衍生物及其制备方法和用途
CN109400562B (zh) * 2018-12-19 2022-12-27 渤海大学 一种含愈创兰烃薁结构的曲酸衍生物、制备方法及其应用

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, Volume 67, No. 11, 11 September 1967, (Columbus, Ohio, US), see pages 5079-50808 Abstract 54032p, & JP,B,42 005 537 (Shionogi & Co., LTD) 7 March 1967 *
Experientia, Volume 37, No. 5, 15 May 1981, Birkhauser Verlag, (Basel, CH), S. IMRE et al.: "Linderazulene, a new Naturally Occurring Pigment from the Gorgonian Paramuricea Chamaeleon", pages 442-443 see the whole article cited in the application *
Experientia, Volume 43, No. 6, 15 June 1987, Birkhauser Verlag, (Basel, CH), S. SAKEMI et al.: "2,3-Dihydrolinderazulene, a New Bioactive Azulene Pigment from the Gorgonian Acalycigorgia sp.", pages 624-625 see the whole article *

Also Published As

Publication number Publication date
JPH01500516A (ja) 1989-02-23
US4755529A (en) 1988-07-05
EP0272310A1 (fr) 1988-06-29
WO1988000191A2 (fr) 1988-01-14

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