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WO1986003380A1 - Compositions dietetiques - Google Patents

Compositions dietetiques Download PDF

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Publication number
WO1986003380A1
WO1986003380A1 PCT/EP1985/000676 EP8500676W WO8603380A1 WO 1986003380 A1 WO1986003380 A1 WO 1986003380A1 EP 8500676 W EP8500676 W EP 8500676W WO 8603380 A1 WO8603380 A1 WO 8603380A1
Authority
WO
WIPO (PCT)
Prior art keywords
compositions according
dietetic
milk
compositions
hypocaloric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP1985/000676
Other languages
English (en)
Inventor
Ennio Iaccheri
Tiziano Crimella
Giuseppe Ponti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Italia SpA
Original Assignee
Boehringer Biochemia Robin SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Biochemia Robin SpA filed Critical Boehringer Biochemia Robin SpA
Publication of WO1986003380A1 publication Critical patent/WO1986003380A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/18—Milk in dried and compressed or semi-solid form
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/18—Peptides; Protein hydrolysates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/19—Dairy proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/20—Agglomerating; Granulating; Tabletting
    • A23P10/28—Tabletting; Making food bars by compression of a dry powdered mixture

Definitions

  • the present invention relates to dietetic composi ⁇ tions in the form of chewable tablets, prepared by com ⁇ pression or extrusion of the components of said dietetic compositions. It is common dietetic practice to treat over-weight persons with dietetic compositions which allow to supply a limited and controlled caloric contribution and which are able to replace one or more of the usual daily meals.
  • dietetic composi ⁇ tions natural or semisynthetic polymers are also added, e.g. guar gum, sodium carboxymethylcellulose, pectins, mucilages, i.e. substances which are easily swollen when in contact with liquids.
  • the above referred dietetic compositions are gene ⁇ rally presented in the form of powders which are to be swallowed after dispersion into liquids, generally water, milk or other hypocaloric aqueous beverages.
  • liquids generally water, milk or other hypocaloric aqueous beverages.
  • their ingestion does not occur in the solid state but always by swallowing of finely divided aqueous suspensions or in the form of diluted mushes prepared at the time of their use. Accordingly, the user needs to have at his disposal the diluting liquid and suitable containers as glasses or shakers for their preparation.
  • small tablets containing exclusively said swelling polymers are also available: in this case, obviously, no nutritional or caloric contribution is gi ⁇ ven; instead, an attempt is made to induce an anorexing effect by virtue to the surfeit feeling which is caused by the swelling in the inner of the stomach.
  • compositions according to the invention are in form of chewable tablets having a weight from 1 to 30 g, preferably from 5 to 10 g, and comprise, according to the intended use, variable amounts of proteins, aminoacids, protein lysates, carbohydrates, lipids, vitamins, carniti- ne or derivatives, salts, milk ferments, swelling agents and flavouring agents.
  • Special examples of swelling agens comprise sodium carboxymethylcellulose, guar gum, pectin, alginic acid.
  • the new formulations, namely the chewable tablets are also useful to prepare dietetic compositions which are to be employed in nutritional and energetic integration in sport activities and/or to be used as dietetic integrators by subjects which are on special diets.
  • the new dietetic formulations are in agreement with the scopes of the invention since they show a practical and extemporaneous use thus allowing the user to obtain at the same time a psychological, ol ⁇ factory and gustatory satisfaction.
  • the form, the size and the weight of the tablets are in no way critical and should be adapted to allow an easy chewing action.
  • the tablets should preferably contain rapidly resorbable carbohydrates (dextrose, fructose, etc.), aminoacids, proteins, carnitine and optionally salts and vitamins.
  • the tables should contain mainly aminoacids or, as a general rule, the components which are insufficient or lacking in the prescribed diets.
  • aminoacids or other substances of unpleasant taste should be present (leucine, methionine, cysteine), they can be used in microincapsulated form or covered wih suitable membranes which allow to mask the taste during chewing and dissolve when in contact with gastric juices.
  • the said components can be joined with known swelling agents as guar flour, pectin, sodium carboxymethylcellulo- se etc., to produce chewable tablets which can be directly ingested, without resorting to previous dispersion in glasses, shakers or other containers as required for known products.
  • swelling agents as guar flour, pectin, sodium carboxymethylcellulo- se etc.
  • hypocaloric dietetic formulations could compromise the intestinal environment. Accordingly, it is greatly desirable to include in the hypocaloric dietetic formulations special components as milk ferments, e.g. Thermobacterium bulgaricum, Strepto ⁇ coccus thermophylus, Lactobacillus acidophilus which can contribute to the preservation of the intestinal bacterial flora. This is greatly desirable when a reduced intake of normal food is present owing to dietetic reasons. It is preferred to use the active milk ferments in amounts from
  • Optimal conditions are, e.g., the drying in a fluidized bed and/or in a forced air circulation oven at 30-40°C and at a filtered sterilized air flow from 0.5 to 20 m /min.
  • powdered lean milk already containing acti ⁇ ve milk ferments or single liophilized milk ferments are added to the normal granulates already described.
  • the preparation procedure of the tablets according to the invention comprises the compression of a mixture of the different components on a rotary or eccentric appara ⁇ tus or the extrusion through a die in which the mixture is forced under very high pressure by a screw.
  • the percentages of the different components in the chewable tablets are not critical and allow to give a balanced nutritional and energetic contribution which is suited for the intended use, as is easily established by people skilled in the art.
  • the tablets according to the invention can be of such shape and size that they can be easily consumed in a single or multiple administration, their consistency being such that a comfortable chewing action is always secured.
  • cocoa are sieved with a 100 mesh/cm stainless steel sieve. Thereafter they are introduced into a quick stand- ing granulator and mixed for 5 min. at a 100 r.p.m. speed.
  • the mixture When homogeneous, the mixture is moistened with 5.5 1 of purified water; the moistening operation, too, is performed in the standing quick granulator, the mass being stirred by horizontal blades which rotate at 100 r.p.m. and by knives rotating at right angles with respect to the blades at 80 r.p.m.
  • the granulate is dried in a fluidized bed desicca ⁇ tor with air thermostated at 60°C for 20 min.
  • the dried granulate is sieved with an oscillator sieve having stainless steel meshes (net mesh separation 1.2 mm) .
  • the granulate is compressed with an eccentric
  • Example 3 The preparation is similar to that described in Example 1, the granulate being compressed under a 3 2 ton/cm pressure to obtain 4,000 tablets weighing 9.50 g and having 2 x 6 x 0.5 size. Four tablets are collected in an aluminium-polyethylene envelope and an envelope is recommended as integrated hypocaloric meal substitute.
  • EXAMPLE 3 The preparation is similar to that described in Example 1, the granulate being compressed under a 3 2 ton/cm pressure to obtain 4,000 tablets weighing 9.50 g and having 2 x 6 x 0.5 size. Four tablets are collected in an aluminium-polyethylene envelope and an envelope is recommended as integrated hypocaloric meal substitute.
  • Example 1 Vitamins are dispersed in the dried granulate before its compression into tablets. According to the procedure of Example 2, tablets of a 9.5 g weight are obtained. Four tablets are collected in an aluminium-polyethylene foil envelope each envelope, being presented as vitamin integrated meal substitute.
  • the preparation is similar to that described in Example 1.
  • the vanilla flavour is dispersed into the dried granulate before its compression into tablets.
  • Example 1 According to the procedure of Example 1, 4,000 tablets weighing 8.04 g are obtained. Four tablets are collected in an aluminium-polyethylene foil envelope, each envelope being presented as hypocaloric meal substi- tute.
  • Example 1 Saccharose monopalmitate and citric acid are dissolved in the purified water used for the granulation of the powder. Orange flavouring is dispersed in the dried granulate before its compression in tablets. After a com-
  • Example 1 4,000 Tablets weighing 8.3 g are obtained.
  • Preparation method The preparation is similar to that described in Example 1.
  • the microincapsulated or not microincapsulated vitamins are dispersed in the dried granulate before its compression in tablets. The compression is performed by using dies which produce tablets of 62 x 35 x 7.8 mm size, weighing 18.6 g. Two tablets are joined in an aluminium- polyethylene foil envelope. Each package is presented as meal substitute integrated with methionine and vitamins.
  • EXAMPLE 8 Dietetic integrator (for sportsmen) L-Leucine kg 2.000 L-Valine kg 2.000
  • Banana flavour g 160 Preparation method The preparation is similar to that described in Example 1. Saccharose monopalmitate is dissolved in the purified water used for granulating the powders.
  • Banana flavour is dispersed in the dried granulate before its compression in tablets. After the usual com-
  • Powdered lean milk with active ferments, Refit (R) , fructose, guar flour and cocoa are sieved with a 100 me- 2 sh/cm stainless steel sieve. Thereafter they are introdu ⁇ ced into a standing quick granulator and mixed for 5 minu ⁇ tes at 100 r.p.m.
  • cocoa butter which was previously melted on a water bath thermostated at 50°C, is added under stirring.
  • the mixture When homogeneous, the mixture is moistened with 5.5 1 of purified water; the moistening operation, too, is performed in the standing quick granulator, the mass being stirred by horizontal blades which rotate at 100 r.p.m. and by knives rotating at right angles with respect to the blades at 80 r.p.m.
  • the granulate is dried in a fluidized bed desiccator with air thermostated at 35°C for 30 min.
  • the dried granulate is sieved with an oscillating sieve having stainless steel meshes (net mesh separation 1.2 mm) .
  • the granulate is compressed with an eccentric com-
  • Powdered milk and fructose are granulated with 2 1 of purified water according to the production method of
  • Example 1 The liophilized milk ferments and the vanilla flavouring are added to the dried granulate. The granulate is compressed in tablets yielding 4',000 tablets weighing 3 g-

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicinal Preparation (AREA)
  • Confectionery (AREA)

Abstract

Des compositions diététiques sous la forme de comprimés à mâcher formés par compression ou par extrusion comprennent des quantités variables de protéines de divers types, d'acides aminés, d'hydrates de carbone, de lipides, de vitamines, de sels, d'agents gonflants et aromatisants, selon l'utilisation en vue. Ces compositions sont utiles comme repas de remplacement hypocaloriques, de même que comme compléments nutritionnels lors de la pratique de sports.
PCT/EP1985/000676 1984-12-10 1985-12-05 Compositions dietetiques Ceased WO1986003380A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT8423966A IT1213255B (it) 1984-12-10 1984-12-10 Composizioni dietetiche.
IT23966A/84 1984-12-10

Publications (1)

Publication Number Publication Date
WO1986003380A1 true WO1986003380A1 (fr) 1986-06-19

Family

ID=11211194

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1985/000676 Ceased WO1986003380A1 (fr) 1984-12-10 1985-12-05 Compositions dietetiques

Country Status (4)

Country Link
BE (1) BE903829A (fr)
FR (1) FR2574254A1 (fr)
IT (1) IT1213255B (fr)
WO (1) WO1986003380A1 (fr)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0237403A1 (fr) * 1986-02-27 1987-09-16 Sanofi S.A. Compositions pour la fabrication de formes unitaires pour boissons instantanées, et procédé de préparation desdites formes unitaires
FR2605854A1 (fr) * 1986-10-30 1988-05-06 Futur Quotidien Sa Complement dietetique a des fins energetiques
US4900566A (en) * 1986-02-08 1990-02-13 The Howard Foundation Confectionary product and a process for producing the same
GB2223925A (en) * 1988-09-09 1990-04-25 Stiff John Edward Dietary supplements
EP0333858A4 (en) * 1986-10-27 1990-12-27 Terumo Kabushiki Kaisha Food for controlling calorie intake
EP0425423A3 (en) * 1989-10-24 1992-05-27 Hoeie, Lars Henrik A process for the preparation of a low-calorie nutritional preparation
DE4212122A1 (de) * 1992-04-10 1993-10-14 Hesch Rolf Dieter Prof Dr Med Diätetisches kalorienarmes Lebensmittel zur Unterstützung ärztlicher und nichtärztlicher Maßnahmen gegen Osteoporose
US6867193B1 (en) 1999-01-19 2005-03-15 Nipro Corporation Amino acid-containing albumin preparation
US9662344B2 (en) 2003-03-20 2017-05-30 The University Of Nottingham Carnitine retention

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03502047A (ja) * 1988-08-18 1991-05-16 バティスタ，オーランド　エイ 蛋白質ベースの膨張可能な低カロリー組成物
DE4128260C2 (de) * 1991-08-26 1995-09-14 Milupa Ag Verfahren zur Herstellung eines phenylalaninfreien Diätetikums in Dragee- oder Tablettenform
PT1048216E (pt) * 1999-04-28 2005-10-31 Nestle Sa Produto de leite seco e densificado

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3360374A (en) * 1965-07-27 1967-12-26 Courtland Lab Process for making a dietary food product
US4042688A (en) * 1975-11-24 1977-08-16 Control Drug, Inc. Method of providing high-protein nutrition by the oral administration of a predigested protein composition
DE2824977A1 (de) * 1978-06-07 1979-12-13 Biochemische Ges Mbh Verfahren zur herstellung von milcheiweisstabletten
EP0009219A1 (fr) * 1978-09-21 1980-04-02 Werner Georg Munk Tranches sèches de produits alimentaires ou de délicatesses en forme de chips et procédé pour leur fabrication
US4220666A (en) * 1978-02-03 1980-09-02 Desert Merchandising, Inc. Sucrose-invert sugar protein product and method of manufacture
EP0028374A1 (fr) * 1979-11-05 1981-05-13 Biotest-Serum-Institut GmbH Produit diététique approprié pour la réduction du poids du corps et pour la sédimentation du niveau du sérum lipide et procédé pour sa fabrication
EP0059535A1 (fr) * 1981-02-06 1982-09-08 MENLEY & JAMES LABORATORIES, LIMITED Compositions de régime contenant des fibres
EP0120705A2 (fr) * 1983-03-30 1984-10-03 NABISCO BRANDS, Inc. Barre nutritive et procédé pour sa préparation
EP0127287A1 (fr) * 1983-04-29 1984-12-05 NABISCO BRANDS, Inc. Barre alimentaire de gomme de guar

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3360374A (en) * 1965-07-27 1967-12-26 Courtland Lab Process for making a dietary food product
US4042688A (en) * 1975-11-24 1977-08-16 Control Drug, Inc. Method of providing high-protein nutrition by the oral administration of a predigested protein composition
US4220666A (en) * 1978-02-03 1980-09-02 Desert Merchandising, Inc. Sucrose-invert sugar protein product and method of manufacture
DE2824977A1 (de) * 1978-06-07 1979-12-13 Biochemische Ges Mbh Verfahren zur herstellung von milcheiweisstabletten
EP0009219A1 (fr) * 1978-09-21 1980-04-02 Werner Georg Munk Tranches sèches de produits alimentaires ou de délicatesses en forme de chips et procédé pour leur fabrication
EP0028374A1 (fr) * 1979-11-05 1981-05-13 Biotest-Serum-Institut GmbH Produit diététique approprié pour la réduction du poids du corps et pour la sédimentation du niveau du sérum lipide et procédé pour sa fabrication
EP0059535A1 (fr) * 1981-02-06 1982-09-08 MENLEY & JAMES LABORATORIES, LIMITED Compositions de régime contenant des fibres
EP0120705A2 (fr) * 1983-03-30 1984-10-03 NABISCO BRANDS, Inc. Barre nutritive et procédé pour sa préparation
EP0127287A1 (fr) * 1983-04-29 1984-12-05 NABISCO BRANDS, Inc. Barre alimentaire de gomme de guar

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4900566A (en) * 1986-02-08 1990-02-13 The Howard Foundation Confectionary product and a process for producing the same
EP0237403A1 (fr) * 1986-02-27 1987-09-16 Sanofi S.A. Compositions pour la fabrication de formes unitaires pour boissons instantanées, et procédé de préparation desdites formes unitaires
EP0333858A4 (en) * 1986-10-27 1990-12-27 Terumo Kabushiki Kaisha Food for controlling calorie intake
US5122379A (en) * 1986-10-27 1992-06-16 Terumo Kabushiki Kaisha Calorie intake-controlling food
FR2605854A1 (fr) * 1986-10-30 1988-05-06 Futur Quotidien Sa Complement dietetique a des fins energetiques
GB2223925A (en) * 1988-09-09 1990-04-25 Stiff John Edward Dietary supplements
EP0425423A3 (en) * 1989-10-24 1992-05-27 Hoeie, Lars Henrik A process for the preparation of a low-calorie nutritional preparation
DE4212122A1 (de) * 1992-04-10 1993-10-14 Hesch Rolf Dieter Prof Dr Med Diätetisches kalorienarmes Lebensmittel zur Unterstützung ärztlicher und nichtärztlicher Maßnahmen gegen Osteoporose
DE4212122C2 (de) * 1992-04-10 1999-07-29 Hesch Rolf Dieter Prof Dr Med Diätetisches energiearmes Lebensmittel zur Unterstützung ärztlicher und nicht-ärztlicher Maßnahmen gegen Osteoporose
US6867193B1 (en) 1999-01-19 2005-03-15 Nipro Corporation Amino acid-containing albumin preparation
US9662344B2 (en) 2003-03-20 2017-05-30 The University Of Nottingham Carnitine retention

Also Published As

Publication number Publication date
BE903829A (fr) 1986-04-01
IT1213255B (it) 1989-12-14
FR2574254A1 (fr) 1986-06-13
IT8423966A0 (it) 1984-12-10

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