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WO1986002639A3 - Application of diethyldithiocarbamate (dtc) to the preparation of a drug and preparation process thereof - Google Patents

Application of diethyldithiocarbamate (dtc) to the preparation of a drug and preparation process thereof

Info

Publication number
WO1986002639A3
WO1986002639A3 PCT/FR1985/000302 FR8500302W WO8602639A3 WO 1986002639 A3 WO1986002639 A3 WO 1986002639A3 FR 8500302 W FR8500302 W FR 8500302W WO 8602639 A3 WO8602639 A3 WO 8602639A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
diethyldithiocarbamate
drug
dtc
application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/FR1985/000302
Other languages
French (fr)
Other versions
WO1986002639A2 (en
Inventor
De La Bastide Rene Ma Bouzinac
Claude Jean Charbonnier
Mircea Musset
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Merieux SA
Original Assignee
Institut Merieux SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut Merieux SA filed Critical Institut Merieux SA
Priority to AT85905222T priority Critical patent/ATE44731T1/en
Priority to DE8585905222T priority patent/DE3571609D1/en
Publication of WO1986002639A2 publication Critical patent/WO1986002639A2/en
Publication of WO1986002639A3 publication Critical patent/WO1986002639A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The drug comprises a preparation of sodium diethyldithiocarbamate purified by dissolution in water.
PCT/FR1985/000302 1984-10-26 1985-10-24 Application of diethyldithiocarbamate (dtc) to the preparation of a drug and preparation process thereof Ceased WO1986002639A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AT85905222T ATE44731T1 (en) 1984-10-26 1985-10-24 USE OF DIAETHYLDITHIOCARBAMATES (DTC) IN THE MANUFACTURE OF A MEDICINAL PRODUCT AND METHOD.
DE8585905222T DE3571609D1 (en) 1984-10-26 1985-10-24 Application of diethyldithiocarbamate (dtc) to the preparation of a drug and preparation process thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR84/16393 1984-10-26
FR8416393A FR2572284B1 (en) 1984-10-26 1984-10-26 NOVEL MODULATOR OF IMMUNITY BASED ON DIETHYLDITHIOCARBAMATE AND PREPARATION METHOD THEREOF

Publications (2)

Publication Number Publication Date
WO1986002639A2 WO1986002639A2 (en) 1986-05-09
WO1986002639A3 true WO1986002639A3 (en) 1986-07-17

Family

ID=9309026

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR1985/000302 Ceased WO1986002639A2 (en) 1984-10-26 1985-10-24 Application of diethyldithiocarbamate (dtc) to the preparation of a drug and preparation process thereof

Country Status (6)

Country Link
EP (2) EP0179694A3 (en)
JP (2) JPS61103827A (en)
CA (2) CA1266058A (en)
DE (1) DE3571609D1 (en)
FR (1) FR2572284B1 (en)
WO (1) WO1986002639A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2620701B1 (en) * 1987-09-18 1990-01-26 Nguyen Dat Xuong NEW CHOLINE COMPOUND, PREPARATION METHOD AND NEW MEDICINES CONTAINING THE SAME
FR2638457B1 (en) * 1988-11-02 1994-05-06 Merieux Institut PROCESS FOR THE SPECIFIC SYNTHESIS OF DITHIOCARBAMIC ACID ESTERS BY SUBSTITUTION OF HYDROXYL SITES ON MONO- OR POLYHYDROXYLATED MOLECULES, PRODUCTS OBTAINED BY THIS PROCESS AND THEIR APPLICATIONS
JP2631039B2 (en) * 1991-01-18 1997-07-16 奈良炭化工業株式会社 desiccant
CA2183547C (en) * 1994-02-18 2002-05-14 Tamara Vasilievna Vorobieva Compositions for treating defective cell functions
WO2021257880A1 (en) * 2020-06-18 2021-12-23 Spring Discovery, Inc. Use of aldh modulators or gasdermin d inhibitors for prevention and treatment of aging and aging-related disorders and for boosting an immune system

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1963223A1 (en) * 1968-12-23 1970-07-16 Haessle Ab Preparations for treating viral infections
DE2445679A1 (en) * 1973-09-25 1975-03-27 Merieux Inst NEW IMMUNITY STIMULATING DRUGS
GB2081094A (en) * 1980-08-08 1982-02-17 Univ Minnesota The use of dithiocarbamic compounds in cancer therapy

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1963223A1 (en) * 1968-12-23 1970-07-16 Haessle Ab Preparations for treating viral infections
DE2445679A1 (en) * 1973-09-25 1975-03-27 Merieux Inst NEW IMMUNITY STIMULATING DRUGS
GB2081094A (en) * 1980-08-08 1982-02-17 Univ Minnesota The use of dithiocarbamic compounds in cancer therapy

Non-Patent Citations (11)

* Cited by examiner, † Cited by third party
Title
Biological Response Modifiers in Human Oncology and Immunology, THOMAS KLEIN et al. (Plenum Publishing Corporation), 1983, G. RENOUX et al.: "Sodium Diethyldithiocarbamate (Imuthiol) and Cancer", pages 223-239, see page 224, lines 1-35; page 225; page 226, lines 1-17; page 228; pages 230-231; page 232, paragraph 1; page 237, lines 5; 12 (cited in the application) *
Cancer Research (Suppl.), Vol. 45, September 1985, A. POMPIDOU et al.: "Isoprinosine and Imuthiol, two Potentially Active Compounds in Patients with AIDS-Related Complex Symptoms", pages 4671s-4673s, see the whole document; note 1 on page 4671s *
Clin. Immunology and Immunopathology, Vol. 15, No. 1, 1980, G. RENOUX el al.: "The Effects of Sodium Diethyldithiocarbamate, Azathioprine, Cyclophosphamide, or Hydrocortisone Acetate Administered alone or in Association for 4 Weeks on the Immune Responses of BALB/c Mice", pages 23-32, see the Abstract; page 24, lines 5-8, 16-17 *
Fluka Katalog 11, 1978, Fluka AG (CH), page 441, see No. 71480 *
Immunomodulatory Drugs and Modifiers of the Biological Response (Elsevier Biomedical Press, 1982), Chapter 9, G. RENOUX et al.: "Immunopharmacology of DTC in Mice and Men", pages 113-132, see the Abstract; page 116, paragraph 9.2.3, lines 1-3; page 117, paragraph 9.2.4, lines 1-3; page 128-130 (cited in the application) *
Int. J. Immunopharmac., Vol. 4, No. 4, 1982, M. ROUMAINTZEFF et al.: "DTC, an Immunopotentiator Specific for T Cells", page 286, see the whole document *
Journal de Pharmacologie (Paris), Vol. 13, Suppl. I, G. RENOUX: "Immunopharmacologie et Pharmacologie du Diethyldithiocarbamate (DTC)", pages 95-134, see page 104, lines 14-39; page 111, lines 4-8, table X; pages 112 and 113; pages 112-125 (cited in the application) *
Journal de Pharmacologie (Paris), Vol. 15, No. 4, 1984, G. RENOUX: "Pharmacological Properties of Imuthiol", pages 486-487, see the whole document *
Journal of Immunopharmacology, Vol. 2, No. 1, 1980, G. RENOUX et al.: "Induction of Differentiation of Human Null Cells into T Lymphocytes under the Influence of Serum of Mice Treated with Sodium Diethyldithiocarbamate", pages 49-59, see the Abstract; page 50, last line; page 51, line 1; page 57, lines 21-23 *
Medicine et Chirurgie Digestives, Vol. 12, No. 7, 1983, G. CHAMPAULT et al.: "L'Immuno-Stimulation en Chirurgie Viscerale essai Therapeutique controle par Diethyl-Dithio-Carbamate de Sodium (124 Patients)", pages 537-543, see page 537, right-hand column, last two lines; Abstract *
Thymus, Vol. 2, No. 3, 1980, G. RENOUX et al.: "Administration of DTC gives Evidence of a role of the Thymus in the Control and Regulation of Factors Inducing Thymocyte Differentiation in the Mouse", pages 139-146, see page 140, paragraph 3; pages 144, 145, discussion *

Also Published As

Publication number Publication date
JPS62501069A (en) 1987-04-30
CA1266058A (en) 1990-02-20
EP0179694A2 (en) 1986-04-30
EP0198878B1 (en) 1989-07-19
EP0198878A1 (en) 1986-10-29
FR2572284B1 (en) 1987-01-09
FR2572284A1 (en) 1986-05-02
JPS61103827A (en) 1986-05-22
CA1277240C (en) 1990-12-04
EP0179694A3 (en) 1986-11-26
DE3571609D1 (en) 1989-08-24
WO1986002639A2 (en) 1986-05-09

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