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UY35733A - MACROCYCLIC INHIBITORS OF PROTEIN / PROTEIN INTERACTIONS PD-1 / PD-L1 AND CD80 (B7-1) / PD-L1 I.P.C. - Google Patents

MACROCYCLIC INHIBITORS OF PROTEIN / PROTEIN INTERACTIONS PD-1 / PD-L1 AND CD80 (B7-1) / PD-L1 I.P.C.

Info

Publication number
UY35733A
UY35733A UY0001035733A UY35733A UY35733A UY 35733 A UY35733 A UY 35733A UY 0001035733 A UY0001035733 A UY 0001035733A UY 35733 A UY35733 A UY 35733A UY 35733 A UY35733 A UY 35733A
Authority
UY
Uruguay
Prior art keywords
protein
interactions
macrocyclic inhibitors
protein interactions
macrocyclic
Prior art date
Application number
UY0001035733A
Other languages
Spanish (es)
Inventor
Michael Matthew Miller
Mapelli Claudio
Martin Patrick Allen
Michael S Bowsher
Eric P Gillis
David R Langley
Mull Eric
Maude A Poirier
Sanghvi Nishith
Li-Qiang Sun
Daniel J Tenney
Kap-Sun Yeung
Zhu Juliang
Kevin W Gillman
Zhao Qiang
Katharine A Grant-Young
Paul Michael Scola
Original Assignee
Bristol Myers Squibb Company Una Corporación Del Estado De Delaware
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Company Una Corporación Del Estado De Delaware filed Critical Bristol Myers Squibb Company Una Corporación Del Estado De Delaware
Priority to UY0001035733A priority Critical patent/UY35733A/en
Publication of UY35733A publication Critical patent/UY35733A/en

Links

Landscapes

  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente descripción proporciona péptidos macrocíclicos novedosos que inhiben las interacciones proteína/proteína PPD-1/PD-L1 y PD-L1/CD80, y por ende, son útiles para la mejora de varias enfermedades, que incluyen el cáncer y las enfermedades infecciosas.The present description provides novel macrocyclic peptides that inhibit the protein / protein interactions PPD-1 / PD-L1 and PD-L1 / CD80, and hence, are useful for the improvement of various diseases, including cancer and infectious diseases.

UY0001035733A 2014-09-12 2014-09-12 MACROCYCLIC INHIBITORS OF PROTEIN / PROTEIN INTERACTIONS PD-1 / PD-L1 AND CD80 (B7-1) / PD-L1 I.P.C. UY35733A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
UY0001035733A UY35733A (en) 2014-09-12 2014-09-12 MACROCYCLIC INHIBITORS OF PROTEIN / PROTEIN INTERACTIONS PD-1 / PD-L1 AND CD80 (B7-1) / PD-L1 I.P.C.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
UY0001035733A UY35733A (en) 2014-09-12 2014-09-12 MACROCYCLIC INHIBITORS OF PROTEIN / PROTEIN INTERACTIONS PD-1 / PD-L1 AND CD80 (B7-1) / PD-L1 I.P.C.

Publications (1)

Publication Number Publication Date
UY35733A true UY35733A (en) 2016-04-01

Family

ID=55747670

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001035733A UY35733A (en) 2014-09-12 2014-09-12 MACROCYCLIC INHIBITORS OF PROTEIN / PROTEIN INTERACTIONS PD-1 / PD-L1 AND CD80 (B7-1) / PD-L1 I.P.C.

Country Status (1)

Country Link
UY (1) UY35733A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10710986B2 (en) 2018-02-13 2020-07-14 Gilead Sciences, Inc. PD-1/PD-L1 inhibitors
US10774071B2 (en) 2018-07-13 2020-09-15 Gilead Sciences, Inc. PD-1/PD-L1 inhibitors
US10899735B2 (en) 2018-04-19 2021-01-26 Gilead Sciences, Inc. PD-1/PD-L1 inhibitors
US11236085B2 (en) 2018-10-24 2022-02-01 Gilead Sciences, Inc. PD-1/PD-L1 inhibitors

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10710986B2 (en) 2018-02-13 2020-07-14 Gilead Sciences, Inc. PD-1/PD-L1 inhibitors
US11555029B2 (en) 2018-02-13 2023-01-17 Gilead Sciences, Inc. PD-1/PD-L1 inhibitors
US10899735B2 (en) 2018-04-19 2021-01-26 Gilead Sciences, Inc. PD-1/PD-L1 inhibitors
US10774071B2 (en) 2018-07-13 2020-09-15 Gilead Sciences, Inc. PD-1/PD-L1 inhibitors
US12269812B2 (en) 2018-07-13 2025-04-08 Gilead Sciences, Inc. PD-1/PD-L1 inhibitors
US11236085B2 (en) 2018-10-24 2022-02-01 Gilead Sciences, Inc. PD-1/PD-L1 inhibitors

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