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UY33097A - DERIVATIVES OF (1h-PIRAZOL-5-IL) UREIDOARILO 1,3-DISUSTITUIDOS AND ITS THERAPEUTIC USES - Google Patents

DERIVATIVES OF (1h-PIRAZOL-5-IL) UREIDOARILO 1,3-DISUSTITUIDOS AND ITS THERAPEUTIC USES

Info

Publication number
UY33097A
UY33097A UY0001033097A UY33097A UY33097A UY 33097 A UY33097 A UY 33097A UY 0001033097 A UY0001033097 A UY 0001033097A UY 33097 A UY33097 A UY 33097A UY 33097 A UY33097 A UY 33097A
Authority
UY
Uruguay
Prior art keywords
ureidoarilo
disustituidos
pirazol
derivatives
therapeutic uses
Prior art date
Application number
UY0001033097A
Other languages
Spanish (es)
Inventor
King-Underwood John
Ito Kasuhiro
Strong Peter
Rapeport William Garth
Catherine Charron
Murray Peter John
Williams Jonathan Gareth
Onions Stuart Thomas
Robert Fenton
Original Assignee
Respivert Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Respivert Ltd filed Critical Respivert Ltd
Publication of UY33097A publication Critical patent/UY33097A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Compuestos de fórmula (I): donde R1, R2, R3, Ar, L, X yQ son tal como se han definido aquí y son útiles para el tratamiento o profiláxis de infecciones virales, especialmente infecciones por el virus de la gripe.Compounds of formula (I): where R1, R2, R3, Ar, L, X and Q are as defined herein and are useful for the treatment or prophylaxis of viral infections, especially influenza virus infections.

UY0001033097A 2009-12-11 2010-12-10 DERIVATIVES OF (1h-PIRAZOL-5-IL) UREIDOARILO 1,3-DISUSTITUIDOS AND ITS THERAPEUTIC USES UY33097A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0921731.6A GB0921731D0 (en) 2009-12-11 2009-12-11 Theraputic uses

Publications (1)

Publication Number Publication Date
UY33097A true UY33097A (en) 2011-06-30

Family

ID=41666983

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001033097A UY33097A (en) 2009-12-11 2010-12-10 DERIVATIVES OF (1h-PIRAZOL-5-IL) UREIDOARILO 1,3-DISUSTITUIDOS AND ITS THERAPEUTIC USES

Country Status (4)

Country Link
GB (1) GB0921731D0 (en)
TW (1) TW201130813A (en)
UY (1) UY33097A (en)
WO (1) WO2011070368A1 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0821227A2 (en) 2007-12-19 2015-06-16 Cancer Rec Tech Ltd Compound, pharmaceutical composition, method for preparing same, use of a compound, method for treating a disease or disorder, for inhibiting raf function and for inhibiting cell proliferation, inhibiting cell cycle progression, promoting apoptosis, or a combination of one or more more of them
GB0905955D0 (en) 2009-04-06 2009-05-20 Respivert Ltd Novel compounds
EP2531502B1 (en) 2010-02-01 2014-04-02 Cancer Research Technology Limited 1-(5-tert-butyl-2-phenyl-2h-pyrazol-3-yl)-3-[2-fluoro-4-(1-methyl-2-oxo-2,3-dihydro-1h-imidazo[4,5-b]pyridin-7-yloxy)-phenyl]-urea and related compounds and their use in therapy
EP2582700B1 (en) 2010-06-17 2016-11-02 Respivert Limited Respiratory formulations containing p38 mapk inhibitors
GB201010196D0 (en) * 2010-06-17 2010-07-21 Respivert Ltd Methods
GB201010193D0 (en) * 2010-06-17 2010-07-21 Respivert Ltd Medicinal use
PL2763984T3 (en) 2011-10-03 2016-10-31 1-pyrazolyl-3-(4-((2-anilinopyrimidin-4-yl)oxy)napththalen-1-yl)ureas as p38 map kinase inhibitors
EP2578582A1 (en) 2011-10-03 2013-04-10 Respivert Limited 1-Pyrazolyl-3-(4-((2-anilinopyrimidin-4-yl)oxy)napththalen-1-yl)ureas as p38 MAP kinase inhibitors
PE20141370A1 (en) 2011-12-09 2014-10-17 Chiesi Farma Spa KINASE INHIBITORS
CA2860479A1 (en) 2011-12-09 2013-06-13 Chiesi Farmaceutici S.P.A. Kinase inhibitors
GB201214750D0 (en) 2012-08-17 2012-10-03 Respivert Ltd Compounds
GB201215357D0 (en) 2012-08-29 2012-10-10 Respivert Ltd Compounds
WO2014033449A1 (en) 2012-08-29 2014-03-06 Respivert Limited Kinase inhibitors
US20150225373A1 (en) 2012-08-29 2015-08-13 Respivert Limited Kinase inhibitors
EP2890460B1 (en) 2012-08-29 2017-02-22 Respivert Limited Kinase inhibitors
EP2925742B1 (en) 2012-11-16 2016-10-26 Respivert Limited Kinase inhibitors
WO2014140582A1 (en) 2013-03-14 2014-09-18 Respivert Limited Kinase inhibitors
EP2981535B8 (en) 2013-04-02 2021-03-10 Oxular Acquisitions Limited Urea derivatives useful as kinase inhibitors
WO2014162121A1 (en) 2013-04-02 2014-10-09 Topivert Pharma Limited Kinase inhibitors based upon n-alkyl pyrazoles
GB201320729D0 (en) 2013-11-25 2014-01-08 Cancer Rec Tech Ltd Therapeutic compounds and their use
GB201320732D0 (en) 2013-11-25 2014-01-08 Cancer Rec Tech Ltd Methods of chemical synthesis
EP3083604A1 (en) 2013-12-20 2016-10-26 Respivert Limited Urea derivatives useful as kinase inhibitors
JP6586098B2 (en) 2014-02-14 2019-10-02 レスピバート・リミテツド Pyrazolyl urea as a kinase inhibitor
MA40774A (en) 2014-10-01 2017-08-08 Respivert Ltd DIARYLEUREA DERIVATIVES AS KINASE P38 INHIBITORS
BR112018067552A2 (en) 2016-04-06 2019-01-08 Topivert Pharma Ltd kinase inhibitors

Family Cites Families (7)

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UA73492C2 (en) 1999-01-19 2005-08-15 Aromatic heterocyclic compounds as antiinflammatory agents
WO2003072569A1 (en) * 2002-02-25 2003-09-04 Boehringer Ingelheim Pharmaceuticals, Inc. 1,4-disubstituted benzofused cycloalkyl urea compounds useful in treating cytokine mediated diseases
MX2007016311A (en) 2005-06-20 2008-03-07 Tibotec Pharm Ltd Heterocyclylaminoalkyl substituted benzimidazoles.
ATE539748T1 (en) 2006-01-27 2012-01-15 Array Biopharma Inc GLUCOKINASE ACTIVATORS
AU2007208156A1 (en) 2006-01-30 2007-08-02 Irm Llc Spiro imidazole derivatives as PPAR modulators
WO2007096764A2 (en) 2006-02-27 2007-08-30 Glenmark Pharmaceuticals S.A. Bicyclic heteroaryl derivatives as cannabinoid receptor modulators
EP2370428B1 (en) * 2008-12-11 2016-08-10 Respivert Limited P38 map kinase inhibitors

Also Published As

Publication number Publication date
GB0921731D0 (en) 2010-01-27
TW201130813A (en) 2011-09-16
WO2011070368A1 (en) 2011-06-16

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