UY33789A - COMBINATION THAT INCLUDES A FAMILY DERIVATIVE OF COMBRETASTATINAS AND CETUXIMAB - Google Patents
COMBINATION THAT INCLUDES A FAMILY DERIVATIVE OF COMBRETASTATINAS AND CETUXIMABInfo
- Publication number
- UY33789A UY33789A UY0001033789A UY33789A UY33789A UY 33789 A UY33789 A UY 33789A UY 0001033789 A UY0001033789 A UY 0001033789A UY 33789 A UY33789 A UY 33789A UY 33789 A UY33789 A UY 33789A
- Authority
- UY
- Uruguay
- Prior art keywords
- cetuximab
- combination
- combretastatinas
- family derivative
- derivative
- Prior art date
Links
- 229960005395 cetuximab Drugs 0.000 title abstract 2
- LGZKGOGODCLQHG-CYBMUJFWSA-N 5-[(2r)-2-hydroxy-2-(3,4,5-trimethoxyphenyl)ethyl]-2-methoxyphenol Chemical compound C1=C(O)C(OC)=CC=C1C[C@@H](O)C1=CC(OC)=C(OC)C(OC)=C1 LGZKGOGODCLQHG-CYBMUJFWSA-N 0.000 abstract 1
- LGZKGOGODCLQHG-UHFFFAOYSA-N combretastatin Natural products C1=C(O)C(OC)=CC=C1CC(O)C1=CC(OC)=C(OC)C(OC)=C1 LGZKGOGODCLQHG-UHFFFAOYSA-N 0.000 abstract 1
- IXWNTLSTOZFSCM-YVACAVLKSA-N ombrabulin Chemical compound C1=C(NC(=O)[C@@H](N)CO)C(OC)=CC=C1\C=C/C1=CC(OC)=C(OC)C(OC)=C1 IXWNTLSTOZFSCM-YVACAVLKSA-N 0.000 abstract 1
- 229950003600 ombrabulin Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Mycology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La invención se refiere a una combinación farmacéutica que comprende un derivado de la familia de las combretastatinas, tal como la ombrabulina, que puede estar en forma de base o en forma de una sal farmacéuticamente aceptable, y cetuximab.The invention relates to a pharmaceutical combination comprising a derivative of the combretastatin family, such as ombrabulin, which may be in the form of a base or in the form of a pharmaceutically acceptable salt, and cetuximab.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1060293A FR2968557A1 (en) | 2010-12-09 | 2010-12-09 | ANTITUMOR COMBINATION COMPRISING A DRIFT OF THE COMBRETASTATIN FAMILY AND THE CETUXIMAB |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UY33789A true UY33789A (en) | 2012-07-31 |
Family
ID=43837735
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UY0001033789A UY33789A (en) | 2010-12-09 | 2011-12-09 | COMBINATION THAT INCLUDES A FAMILY DERIVATIVE OF COMBRETASTATINAS AND CETUXIMAB |
Country Status (5)
| Country | Link |
|---|---|
| AR (1) | AR084169A1 (en) |
| FR (1) | FR2968557A1 (en) |
| TW (1) | TW201306833A (en) |
| UY (1) | UY33789A (en) |
| WO (1) | WO2012076688A1 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016503399A (en) * | 2012-10-25 | 2016-02-04 | ノバルティス アーゲー | combination |
| US20170128592A1 (en) * | 2015-10-01 | 2017-05-11 | Indian Institute Of Technology, Bombay | Targeted polymeric nano-complexes as drug delivery system |
| CN112225673B (en) * | 2020-11-13 | 2022-08-02 | 义乌市华耀医药科技有限公司 | Amino combretastatin derivative and application thereof |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4996237A (en) | 1987-01-06 | 1991-02-26 | Arizona Board Of Regents | Combretastatin A-4 |
| TW325458B (en) | 1993-09-08 | 1998-01-21 | Ajinomoto Kk | Stilbene derivatives and pharmaceutical compositions comprising the same for anti-cancer |
| US5731353A (en) | 1993-09-08 | 1998-03-24 | Ajinomoto Co., Inc. | Stilbene derivatives and pharmaceutical compositions containing them |
| TW334418B (en) | 1995-03-07 | 1998-06-21 | Ajinomoto Kk | Stilbene derivatives and pharmaceutical compositions |
| CA2326761C (en) | 1998-04-03 | 2008-02-19 | Ajinomoto Co., Inc. | Antitumor agent |
| US20020183266A1 (en) | 2001-03-15 | 2002-12-05 | Aventis Pharma, S.A. | Combination comprising combretastatin and anticancer agents |
| ATE489080T1 (en) | 2001-06-25 | 2010-12-15 | Ajinomoto Kk | ANTITUMORAL AGENTS |
| FR2838437B1 (en) | 2002-04-11 | 2004-06-04 | Aventis Pharma Sa | PROCESSES FOR THE PREPARATION OF COMBRETASTATINS |
| GB0410817D0 (en) * | 2004-05-14 | 2004-06-16 | Angiogene Pharm Ltd | Vascular damaging therapy |
| FR2895258B1 (en) | 2005-12-22 | 2008-03-21 | Aventis Pharma Sa | COMBINATION COMPRISING COMBRETASTATIN AND ANTICANCER AGENTS |
| JP2011506455A (en) * | 2007-12-13 | 2011-03-03 | ノバルティス アーゲー | Combination of therapeutic agents for treating cancer |
| US20090209496A1 (en) * | 2008-02-15 | 2009-08-20 | David Chaplin | Methods and compositions for enhancing the efficacy of rtk inhibitors |
| FR2945210B1 (en) * | 2009-05-07 | 2011-07-01 | Sanofi Aventis | ANTITUMOR COMBINATION COMPRISING AVE8062 AND SORAFENIB |
-
2010
- 2010-12-09 FR FR1060293A patent/FR2968557A1/en active Pending
-
2011
- 2011-12-06 AR ARP110104553A patent/AR084169A1/en not_active Application Discontinuation
- 2011-12-09 TW TW100145626A patent/TW201306833A/en unknown
- 2011-12-09 WO PCT/EP2011/072310 patent/WO2012076688A1/en not_active Ceased
- 2011-12-09 UY UY0001033789A patent/UY33789A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TW201306833A (en) | 2013-02-16 |
| WO2012076688A1 (en) | 2012-06-14 |
| FR2968557A1 (en) | 2012-06-15 |
| AR084169A1 (en) | 2013-04-24 |
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