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UY33442A - PROCEDURE FOR THE PREPARATION OF DIADCIDE 3,6,9-TRIAZA-3,6,9-TRIS (CARBOXIMETHYL) -4- (4-ETOXIBENCIL) -CONDECANOICO CRISTALINO AND THE USE FOR THE PREPARATION OF PRIMOVISTO - Google Patents

PROCEDURE FOR THE PREPARATION OF DIADCIDE 3,6,9-TRIAZA-3,6,9-TRIS (CARBOXIMETHYL) -4- (4-ETOXIBENCIL) -CONDECANOICO CRISTALINO AND THE USE FOR THE PREPARATION OF PRIMOVISTO

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Publication number
UY33442A
UY33442A UY33442A UY33442A UY33442A UY 33442 A UY33442 A UY 33442A UY 33442 A UY33442 A UY 33442A UY 33442 A UY33442 A UY 33442A UY 33442 A UY33442 A UY 33442A
Authority
UY
Uruguay
Prior art keywords
preparation
triaza
tris
primovisto
etoxibencil
Prior art date
Application number
UY33442A
Other languages
Spanish (es)
Inventor
Dr Johannes Platzek
Dr Wilhelm Trentmann
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE201010023890 external-priority patent/DE102010023890A1/en
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Publication of UY33442A publication Critical patent/UY33442A/en

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La invención se refiere a un procedimiento para la preparación de diácido 3,6,9-triaza-3,6,9-tris(carboximetil)-4-(4-etoxibencil)-undecanoico cristalino de la fórmula I por saponificación de éster di-ter-butílico del diácido 3.6.9-triaza-3,6,9-tris(ter-butoxicarbonilmetil)-4-(4-etoxibencil)-undecanoico de la fórmula II en una soluciónacuosa de hidróxido de metal alcalino y al uso de diácido 3,6,9-triaza-3,6,9-tris(carboximetil)-4-(4-etoxibencil)-undecanoico de la fórmula I para la preparación del complejo de gadolinio de diácido 3.6.9-triaza-3,6,9-tris(carboximetil)-4-(4-etoxibencil)-undecanoicoThe invention relates to a process for the preparation of crystalline crystalline 3,6,9-triaza-3,6,9-tris (carboxymethyl) -4- (4-ethoxybenzyl) -undecanoic acid of formula I by saponification of di ester -3,6,9-triaza-3,6,9-tris (tert-butoxycarbonylmethyl) -4- (4-ethoxybenzyl) -undecanoic diacid-butyl ester of the formula II in an aqueous solution of alkali metal hydroxide and the use of 3,6,9-triaza-3,6,9-tris (carboxymethyl) -4- (4-ethoxybenzyl) -undecanoic diacid of the formula I for the preparation of the gadolinium complex of diacid 3.6.9-triaza-3, 6,9-tris (carboxymethyl) -4- (4-ethoxybenzyl) -undecanoic

UY33442A 2010-06-11 2011-06-09 PROCEDURE FOR THE PREPARATION OF DIADCIDE 3,6,9-TRIAZA-3,6,9-TRIS (CARBOXIMETHYL) -4- (4-ETOXIBENCIL) -CONDECANOICO CRISTALINO AND THE USE FOR THE PREPARATION OF PRIMOVISTO UY33442A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE201010023890 DE102010023890A1 (en) 2010-06-11 2010-06-11 Preparing crystalline 3,6,9-triaza-3,6,9-tris(carboxymethyl)-4-(ethoxybenzyl)-undecanedioic acid comprises hydrolyzing 3,6,9-triaza-3,6,9-tris(tert-butoxy-carbonylmethyl)-4-(ethoxybenzyl)-undecanedioic acid-ditert-butylester and acidifying
BRPI2002466 2010-07-19

Publications (1)

Publication Number Publication Date
UY33442A true UY33442A (en) 2012-01-31

Family

ID=45510457

Family Applications (1)

Application Number Title Priority Date Filing Date
UY33442A UY33442A (en) 2010-06-11 2011-06-09 PROCEDURE FOR THE PREPARATION OF DIADCIDE 3,6,9-TRIAZA-3,6,9-TRIS (CARBOXIMETHYL) -4- (4-ETOXIBENCIL) -CONDECANOICO CRISTALINO AND THE USE FOR THE PREPARATION OF PRIMOVISTO

Country Status (1)

Country Link
UY (1) UY33442A (en)

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Effective date: 20200807