UY32429A - DERIVATIVES OF N - [(6-AZA-BICICLO [3.2.1] OCT-1-IL) -ARIL-METIL] -BENZAMIDA, ITS PREPARATION AND ITS APPLICATION IN THERAPEUTICS - Google Patents
DERIVATIVES OF N - [(6-AZA-BICICLO [3.2.1] OCT-1-IL) -ARIL-METIL] -BENZAMIDA, ITS PREPARATION AND ITS APPLICATION IN THERAPEUTICSInfo
- Publication number
- UY32429A UY32429A UY0001032429A UY32429A UY32429A UY 32429 A UY32429 A UY 32429A UY 0001032429 A UY0001032429 A UY 0001032429A UY 32429 A UY32429 A UY 32429A UY 32429 A UY32429 A UY 32429A
- Authority
- UY
- Uruguay
- Prior art keywords
- aza
- oct
- preparation
- application
- derivatives
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- 102000010726 Glycine Plasma Membrane Transport Proteins Human genes 0.000 abstract 1
- 108010063380 Glycine Plasma Membrane Transport Proteins Proteins 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000006806 disease prevention Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Psychology (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
Abstract
La presente invención se refiere a derivados de N-[6-aza-bicilo[3.2.1]OCT-1-IL)-aril-metil]-benzamida de fórmula general (I); a su preparación y procedimiento de síntesis, y su aplicación en terapeutica, en el tratamiento o la prevención de enfermedades que implican los transportadores de la glicina Glyt1.The present invention relates to N- [6-aza-bicylic [3.2.1] OCT-1-IL) -aryl-methyl] -benzamide derivatives of general formula (I); to its preparation and synthesis procedure, and its application in therapy, in the treatment or prevention of diseases that involve Glyt1 glycine transporters.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0900579A FR2941954B1 (en) | 2009-02-10 | 2009-02-10 | N- (6-AZA-BICYCLO ° 3.2.1! OCT-1-YL) -ARYL-METHYL DERIVATIVES BENZAMIDE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UY32429A true UY32429A (en) | 2010-09-30 |
Family
ID=40935769
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UY0001032429A UY32429A (en) | 2009-02-10 | 2010-02-10 | DERIVATIVES OF N - [(6-AZA-BICICLO [3.2.1] OCT-1-IL) -ARIL-METIL] -BENZAMIDA, ITS PREPARATION AND ITS APPLICATION IN THERAPEUTICS |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP2396335A1 (en) |
| JP (1) | JP2012517412A (en) |
| KR (1) | KR20110118813A (en) |
| CN (1) | CN102388050A (en) |
| AR (1) | AR075380A1 (en) |
| AU (1) | AU2010212703A1 (en) |
| BR (1) | BRPI1008544A2 (en) |
| CA (1) | CA2751866A1 (en) |
| FR (1) | FR2941954B1 (en) |
| IL (1) | IL214487A0 (en) |
| MX (1) | MX2011008459A (en) |
| SG (1) | SG173607A1 (en) |
| TW (1) | TW201034667A (en) |
| UY (1) | UY32429A (en) |
| WO (1) | WO2010092287A1 (en) |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2861076B1 (en) * | 2003-10-17 | 2006-01-06 | Sanofi Synthelabo | N-HETEROCYCLYMETHYLBENZAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE |
| FR2861070B1 (en) * | 2003-10-17 | 2006-01-06 | Sanofi Synthelabo | DERIVATIVES OF N- [PHENYL (PYRROLIDIN-2-YL) METHYL] BENZAMIDE AND N - [(AZEPAN-2-YL) PHENYLMETHYL] BENZAMIDE, THEIR PREPARATION AND THEIR THERAPEUTIC USE |
| WO2005058317A1 (en) * | 2003-12-18 | 2005-06-30 | Glaxo Group Limited | Glycine transporter-1 inhibirors |
| AU2006309050B2 (en) * | 2005-10-28 | 2012-08-16 | Merck Sharp & Dohme Corp. | Piperidine glycine transporter inhibitors |
| TW200829238A (en) * | 2006-11-30 | 2008-07-16 | Cenerx Biopharma Inc | Dialkylamino alkyl esters of pivagabine as medicaments for the treatment of central nervous system disorders |
| TW200911808A (en) * | 2007-07-23 | 2009-03-16 | Astrazeneca Ab | Novel compounds |
-
2009
- 2009-02-10 FR FR0900579A patent/FR2941954B1/en not_active Expired - Fee Related
-
2010
- 2010-02-09 SG SG2011057213A patent/SG173607A1/en unknown
- 2010-02-09 WO PCT/FR2010/050204 patent/WO2010092287A1/en not_active Ceased
- 2010-02-09 TW TW099104006A patent/TW201034667A/en unknown
- 2010-02-09 BR BRPI1008544A patent/BRPI1008544A2/en not_active Application Discontinuation
- 2010-02-09 AR ARP100100345A patent/AR075380A1/en unknown
- 2010-02-09 KR KR1020117021204A patent/KR20110118813A/en not_active Withdrawn
- 2010-02-09 AU AU2010212703A patent/AU2010212703A1/en not_active Abandoned
- 2010-02-09 CN CN2010800156289A patent/CN102388050A/en active Pending
- 2010-02-09 MX MX2011008459A patent/MX2011008459A/en not_active Application Discontinuation
- 2010-02-09 EP EP10708304A patent/EP2396335A1/en not_active Withdrawn
- 2010-02-09 JP JP2011548759A patent/JP2012517412A/en not_active Withdrawn
- 2010-02-09 CA CA2751866A patent/CA2751866A1/en not_active Abandoned
- 2010-02-10 UY UY0001032429A patent/UY32429A/en not_active Application Discontinuation
-
2011
- 2011-08-07 IL IL214487A patent/IL214487A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20110118813A (en) | 2011-11-01 |
| WO2010092287A1 (en) | 2010-08-19 |
| FR2941954B1 (en) | 2011-04-08 |
| EP2396335A1 (en) | 2011-12-21 |
| JP2012517412A (en) | 2012-08-02 |
| SG173607A1 (en) | 2011-09-29 |
| MX2011008459A (en) | 2011-12-16 |
| CN102388050A (en) | 2012-03-21 |
| CA2751866A1 (en) | 2010-08-19 |
| BRPI1008544A2 (en) | 2016-03-15 |
| FR2941954A1 (en) | 2010-08-13 |
| AR075380A1 (en) | 2011-03-30 |
| AU2010212703A1 (en) | 2011-09-01 |
| IL214487A0 (en) | 2011-09-27 |
| TW201034667A (en) | 2010-10-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY1124000T1 (en) | SUBSTITUTED 5-FLUORO-1H-PYRAZOLOPYRIDINES IN CRYSTALLINE FORM | |
| EA201190217A1 (en) | SUBSTITUTED 2-ACETAMIDO-5-ARIL-1,2,4-TRIAZOLONES AND THEIR APPLICATION | |
| MX2011008634A (en) | Aminotetraline derivatives, pharmaceutical compositions containing them, and their use in therapy. | |
| CR20140392A (en) | SUBSTITUTED DIHYDROPIRAZOLONES | |
| BR112013000920A2 (en) | compounds for reducing beta-amyloid production | |
| EA201290183A1 (en) | BENZODIAZEPINUM INHIBITOR BROMODOMENE | |
| ECSP109903A (en) | DERIVATIVES OF PIRAZINONA AND ITS USE IN THE TREATMENT OF PULMONARY DISEASES | |
| UA96785C2 (en) | Substituted oxindole derivatives and use thereof as vasopressin receptor ligands | |
| EA201270225A1 (en) | COMPOUNDS TO REDUCE β-AMYLOID PRODUCTS | |
| EA201390908A1 (en) | DERIVATIVES OF BICYCLO [3.2.1] OCTYLAMIDE AND THEIR APPLICATION | |
| EA201070327A1 (en) | CATECHOLAMINE DERIVATIVES AND THEIR DEVICES | |
| ECSP13012668A (en) | 1-BENCILCICLOALQUILCARBOXÍLICOS ACIDS SUBSTITUTED AND ITS USE | |
| MA32784B1 (en) | Aryl compounds replaced by heterocyclic ring act as inhibitors of induced hypoxia agents | |
| SV2011003802A (en) | USEFUL TRIAZOL DERIVATIVES FOR THE TREATMENT OF DISEASES | |
| CR20110318A (en) | COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS TO BE USED IN THE TREATMENT OF METABOLIC DISORDERS | |
| EA201000098A1 (en) | HINAZOLINAMIDE DERIVATIVES | |
| BRPI0923300A2 (en) | "cilostazol nitrate derivatives for the treatment of vascular and metabolic diseases" | |
| UY31765A (en) | SUBSTITUTED DIHYDROPIRAZOLONAS AND ITS USE | |
| EA200802223A1 (en) | 1,5-DIPHENYLPYRAZOLES II AS HSP90 INHIBITORS | |
| IN2012DN02502A (en) | ||
| BR112012022109A2 (en) | aminoindan derivatives, their preparation and their application in therapeutic products | |
| BR112013018298A2 (en) | compounds for reducing beta-amyloid production | |
| ECSP109961A (en) | DERIVATIVES OF INDOL-2-ONA DISSTITUTED IN 3, ITS PREPARATION AND ITS APPLICATION IN THERAPEUTICS | |
| BRPI0917245A8 (en) | ISOQUINOLINONE DERIVATIVE COMPOUNDS AND THEIR PHARMACEUTICAL COMPOSITION | |
| UY33568A (en) | COMPOUNDS THAT INTERACT WITH GLUCOCINASE REGULATING PROTEIN FOR THE TREATMENT OF DIABETES. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 109 | Application deemed to be withdrawn |
Effective date: 20130313 |