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UY31720A1 - Procedimiento y aparato para separar particulas en un fluido - Google Patents

Procedimiento y aparato para separar particulas en un fluido

Info

Publication number
UY31720A1
UY31720A1 UY031720A UY31720A UY31720A1 UY 31720 A1 UY31720 A1 UY 31720A1 UY 031720 A UY031720 A UY 031720A UY 31720 A UY31720 A UY 31720A UY 31720 A1 UY31720 A1 UY 31720A1
Authority
UY
Uruguay
Prior art keywords
fluid
channel
flow
separating particles
constriction
Prior art date
Application number
UY031720A
Other languages
English (en)
Inventor
Martin Arundell
Villarreal Angeles Ivon Rodriguez
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of UY31720A1 publication Critical patent/UY31720A1/es

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • G01N33/491Blood by separating the blood components
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D21/00Separation of suspended solid particles from liquids by sedimentation
    • B01D21/0039Settling tanks provided with contact surfaces, e.g. baffles, particles
    • B01D21/0051Plurality of tube like channels
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D21/00Separation of suspended solid particles from liquids by sedimentation
    • B01D21/0087Settling tanks provided with means for ensuring a special flow pattern, e.g. even inflow or outflow
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502753Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D2221/00Applications of separation devices
    • B01D2221/10Separation devices for use in medical, pharmaceutical or laboratory applications, e.g. separating amalgam from dental treatment residues
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0647Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0652Sorting or classification of particles or molecules
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0816Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/08Regulating or influencing the flow resistance
    • B01L2400/084Passive control of flow resistance
    • B01L2400/086Passive control of flow resistance using baffles or other fixed flow obstructions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Ecology (AREA)
  • General Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Separation Of Solids By Using Liquids Or Pneumatic Power (AREA)
  • Filtering Of Dispersed Particles In Gases (AREA)

Abstract

Aparato y procedimiento para separar partículas dispersadas en un fluido. El aparato incluye, en serie, un canal de entrada, un canal de constricción y un canal de salida, estando configurados los canales para recibir una dispersión de fluido y crear en la unión del canal de constricción y de salida un flujo y una segunda zona de flujo, en el que la segunda zona de flujo presenta una concentración de partículas inferior que la primera zona de flujo. Se dispone un canal de recogida en la unión del canal de constricción y de salida para recoger fluido de la segunda zona de flujo.
UY031720A 2008-03-19 2009-03-19 Procedimiento y aparato para separar particulas en un fluido UY31720A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3780508P 2008-03-19 2008-03-19

Publications (1)

Publication Number Publication Date
UY31720A1 true UY31720A1 (es) 2009-09-30

Family

ID=40600233

Family Applications (1)

Application Number Title Priority Date Filing Date
UY031720A UY31720A1 (es) 2008-03-19 2009-03-19 Procedimiento y aparato para separar particulas en un fluido

Country Status (6)

Country Link
US (1) US20110084033A1 (es)
EP (1) EP2276549A1 (es)
CL (1) CL2009000671A1 (es)
TW (1) TW200951061A (es)
UY (1) UY31720A1 (es)
WO (1) WO2009115575A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101844413B1 (ko) 2010-06-10 2018-04-04 삼성전자주식회사 Moff 채널을 이용한 표적 입자 분리 장치 및 분리 방법
US8590710B2 (en) * 2010-06-10 2013-11-26 Samsung Electronics Co., Ltd. Target particles-separating device and method using multi-orifice flow fractionation channel
US8980106B2 (en) 2010-12-15 2015-03-17 Abbott Laboratories Apparatus and method for separation of whole blood into plasma or serum and cells
DE102012206371A1 (de) * 2012-04-18 2013-10-24 Siemens Ag Durchflusssystem mit einer Rückhaltestruktur für Partikel und dessen Verwendung
US8934700B2 (en) * 2013-03-04 2015-01-13 Caliper Life Sciences, Inc. High-throughput single-cell imaging, sorting, and isolation
JP6003772B2 (ja) * 2013-03-29 2016-10-05 ソニー株式会社 マイクロチップ及びマイクロチップの製造方法
US20140309553A1 (en) * 2013-04-11 2014-10-16 Rarecyte, Inc. Kits and methods for separating a target analyte from a suspension
WO2017104812A1 (ja) * 2015-12-17 2017-06-22 マイクロ化学技研株式会社 粒子浮遊液からの媒体の分離方法及び装置
JP6518016B2 (ja) 2015-12-24 2019-05-22 コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. 細胞懸濁液の決定のための方法及びシステム
US12383389B2 (en) * 2018-04-04 2025-08-12 The General Hospital Corporation Microfluidic systems and methods to denude mammalian oocytes
GB201820944D0 (en) * 2018-12-21 2019-02-06 Ufraction8 Ltd Microfluid device

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3725271A (en) * 1964-01-29 1973-04-03 Giannotti Ass Apparatus and method for separating particles from a flow of fluid
US5549721A (en) * 1994-12-02 1996-08-27 Shchipachev; Viktor Cell for gas cleaning
US6175752B1 (en) * 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
AU773950B2 (en) * 1999-07-16 2004-06-10 Applera Corporation High density electrophoresis device and method
DE10150549A1 (de) * 2001-10-12 2003-04-17 Roche Diagnostics Gmbh Verfahren und Trennmodul zum Abtrennen von Partikeln aus einer Dispersion, insbesondere von Blutkörperchen aus Blut
US7517453B2 (en) * 2003-03-01 2009-04-14 The Trustees Of Boston University Microvascular network device
WO2006056219A1 (en) * 2004-11-24 2006-06-01 Preventor Utbc Gmbh Process for separation of dispersions and an apparatus
US20060204403A1 (en) * 2005-02-28 2006-09-14 Careside Medical, Llc Micro-fluidic fluid separation device and method
WO2009051734A1 (en) * 2007-10-17 2009-04-23 The General Hospital Corporation Microchip-based devices for capturing circulating tumor cells and methods of their use

Also Published As

Publication number Publication date
US20110084033A1 (en) 2011-04-14
EP2276549A1 (en) 2011-01-26
WO2009115575A1 (en) 2009-09-24
TW200951061A (en) 2009-12-16
CL2009000671A1 (es) 2011-02-18

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