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UY31676A1 - "derivados de 3-metil-imidiazo-[1,2-b]-piridazina" - Google Patents

"derivados de 3-metil-imidiazo-[1,2-b]-piridazina"

Info

Publication number
UY31676A1
UY31676A1 UY031676A UY31676A UY31676A1 UY 31676 A1 UY31676 A1 UY 31676A1 UY 031676 A UY031676 A UY 031676A UY 31676 A UY31676 A UY 31676A UY 31676 A1 UY31676 A1 UY 31676A1
Authority
UY
Uruguay
Prior art keywords
compound
imidiazo
piridazina
derivatives
methyl
Prior art date
Application number
UY031676A
Other languages
English (en)
Inventor
Frederic Stauffer
Melanie Stang
Carsten Spanka
Joseph Schoepfer
Clive Mccarthy
Pascal Furet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39672115&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY31676(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of UY31676A1 publication Critical patent/UY31676A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Compuestos de la fórmula (I) y sales de los mismos: en donde los sustituyentes son como se definen en la memoria descriptiva; aplicación de dicho compuesto en un proceso para el tratamiento del cuerpo humano o animal, en particular con respecto una enfermedad mediada por la cinasa de tirosina c-Met; uso de dicho compuesto para la fabricación de un medicamento para tratamiento de dichas enfermedades; composiciones farmacéuticas comprendiendo dicho compuesto , opcionalmente en la presencia de un componente de combinación; procesos para la preparación de un compuesto de la fórmula (I).
UY031676A 2008-02-28 2009-02-26 "derivados de 3-metil-imidiazo-[1,2-b]-piridazina" UY31676A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP08152068 2008-02-28

Publications (1)

Publication Number Publication Date
UY31676A1 true UY31676A1 (es) 2009-09-30

Family

ID=39672115

Family Applications (1)

Application Number Title Priority Date Filing Date
UY031676A UY31676A1 (es) 2008-02-28 2009-02-26 "derivados de 3-metil-imidiazo-[1,2-b]-piridazina"

Country Status (25)

Country Link
US (1) US8822468B2 (es)
EP (1) EP2265614A1 (es)
JP (1) JP5576802B2 (es)
KR (1) KR20100128305A (es)
CN (1) CN102015716B (es)
AR (1) AR070487A1 (es)
AU (1) AU2009218459A1 (es)
BR (1) BRPI0908504A2 (es)
CA (1) CA2717034A1 (es)
CL (1) CL2009000443A1 (es)
CO (1) CO6300957A2 (es)
CR (1) CR11620A (es)
DO (1) DOP2010000263A (es)
EA (1) EA201001365A1 (es)
EC (1) ECSP10010427A (es)
IL (1) IL207434A0 (es)
MA (1) MA32167B1 (es)
MX (1) MX2010009414A (es)
NI (1) NI201000145A (es)
PE (1) PE20091468A1 (es)
SM (1) SMAP201000112A (es)
TW (1) TW200940545A (es)
UY (1) UY31676A1 (es)
WO (1) WO2009106577A1 (es)
ZA (1) ZA201005602B (es)

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US20110195066A1 (en) * 2010-02-05 2011-08-11 Auspex Pharmaceuticals, Inc. Quinoline inhibitors of tyrosine kinase
US20130315895A1 (en) * 2010-07-01 2013-11-28 Takeda Pharmaceutical Company Limited COMBINATION OF A cMET INHIBITOR AND AN ANTIBODY TO HGF AND/OR cMET
AR085183A1 (es) 2010-07-30 2013-09-18 Lilly Co Eli Compuesto 6-(1-metil-1h-pirazol-4-il)-3-(2-metil-2h-indazol-5-iltio)-[1,2,4]triazol[4,3-b]piridazina, composicion farmaceutica que lo comprende y uso para preparar un medicamento util para tratar cancer
US8637516B2 (en) * 2010-09-09 2014-01-28 Irm Llc Compounds and compositions as TRK inhibitors
ES2610366T3 (es) * 2011-06-22 2017-04-27 Bayer Intellectual Property Gmbh Heterociclil-aminoimidazopiridazinas
CN103958509B (zh) * 2011-09-15 2015-12-23 诺华股份有限公司 作为酪氨酸激酶抑制剂的6-取代的3-(喹啉-6-基硫代)-[1,2,4]三唑并[4,3-a]吡啶化合物
WO2013038362A1 (en) 2011-09-15 2013-03-21 Novartis Ag 6 - substituted 3 - (quinolin- 6 - ylthio) - [1,2,4] triazolo [4, 3 -a] pyradines as tyrosine kinase
CN103122000B (zh) * 2012-09-03 2013-12-25 中美冠科生物技术（太仓）有限公司 用作抗肿瘤药物的高选择性的c-Met激酶抑制剂
TWI600654B (zh) 2012-11-19 2017-10-01 艾姆公司 用於治療寄生蟲疾病之化合物及組合物
CN105431148A (zh) 2013-03-07 2016-03-23 加利菲亚生物公司 混合谱系激酶抑制剂及治疗方法
AR097543A1 (es) * 2013-09-06 2016-03-23 Lexicon Pharmaceuticals Inc COMPUESTOS BASADOS EN IMIDAZO[1,2-b]PIRIDAZINA, COMPOSICIONES QUE LOS COMPRENDEN Y SUS MÉTODOS DE USO
CN105326793A (zh) * 2014-08-06 2016-02-17 中美冠科生物技术（太仓）有限公司 一种包含c-Met激酶抑制剂的固体分散体及其制备方法和用途
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SI3233839T1 (sl) * 2014-12-19 2019-12-31 Janssen Pharmaceutica Nv Heterociklil vezani derivati imidazopiridazina kot inhibitorji PI3Kbeta
JP7117293B2 (ja) * 2016-09-16 2022-08-12 ヘルムホルツ ツェントゥルム ミュンヘン ドイチェス フォルシュングスツェントゥルム フューア ゲズントハイト ウント ウムヴェルト （ゲーエムベーハー） Ｔｒａｆ６阻害剤
US11185548B2 (en) * 2016-12-23 2021-11-30 Helmholtz Zentrum Munchen—Deutsches Forschungszentrum Für Gesundheit Und Umwelt (Gmbh) Inhibitors of cytochrome P450 family 7 subfamily B member 1 (CYP7B1) for use in treating diseases
WO2018138050A1 (de) 2017-01-26 2018-08-02 Bayer Aktiengesellschaft Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel
WO2018237349A1 (en) * 2017-06-23 2018-12-27 University Of Washington Inhibitors of typed 1 methionyl-trna synthetase and methods of using them
JP7296992B2 (ja) * 2018-05-28 2023-06-23 エフ． ホフマン－ラ ロシュ アーゲー 細菌感染症の処置および予防のための新規オキソキノリジン化合物
JP7712932B2 (ja) * 2019-12-18 2025-07-24 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア Ｌｉｎ２８の阻害剤及びその使用方法
CN119081395B (zh) * 2024-09-07 2025-03-18 广东环塑众创实业有限公司 一种耐高温尼龙工程塑料及其制备方法

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Also Published As

Publication number Publication date
AR070487A1 (es) 2010-04-07
NI201000145A (es) 2011-03-02
ZA201005602B (en) 2011-04-28
CR11620A (es) 2010-10-08
MA32167B1 (fr) 2011-03-01
CN102015716A (zh) 2011-04-13
TW200940545A (en) 2009-10-01
MX2010009414A (es) 2010-09-24
EA201001365A1 (ru) 2011-04-29
DOP2010000263A (es) 2010-09-30
IL207434A0 (en) 2010-12-30
AU2009218459A1 (en) 2009-09-03
CO6300957A2 (es) 2011-07-21
ECSP10010427A (es) 2010-09-30
US8822468B2 (en) 2014-09-02
JP2011513279A (ja) 2011-04-28
JP5576802B2 (ja) 2014-08-20
CN102015716B (zh) 2014-09-17
CL2009000443A1 (es) 2010-09-10
EP2265614A1 (en) 2010-12-29
KR20100128305A (ko) 2010-12-07
US20090264406A1 (en) 2009-10-22
WO2009106577A1 (en) 2009-09-03
BRPI0908504A2 (pt) 2015-08-11
PE20091468A1 (es) 2009-10-22
SMAP201000112A (it) 2010-11-12
CA2717034A1 (en) 2009-09-03

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Effective date: 20180831