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UY30536A1 - SYSTEM OF CONTROLLED PHARMACEUTICAL RELEASE, PARTICULARLY ORAL ADMINISTRATION OF ACTIVE SUBSTANCES WITH SOLUBILITIES OF PH, PREPARATION AND APPLICATION. - Google Patents

SYSTEM OF CONTROLLED PHARMACEUTICAL RELEASE, PARTICULARLY ORAL ADMINISTRATION OF ACTIVE SUBSTANCES WITH SOLUBILITIES OF PH, PREPARATION AND APPLICATION.

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Publication number
UY30536A1
UY30536A1 UY30536A UY30536A UY30536A1 UY 30536 A1 UY30536 A1 UY 30536A1 UY 30536 A UY30536 A UY 30536A UY 30536 A UY30536 A UY 30536A UY 30536 A1 UY30536 A1 UY 30536A1
Authority
UY
Uruguay
Prior art keywords
solubilities
active substances
preparation
application
oral administration
Prior art date
Application number
UY30536A
Other languages
Spanish (es)
Inventor
Florian Sommer
Farl G Wagner
Thomas Friedl
Nantharat Pearnchob
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Priority to UY30536A priority Critical patent/UY30536A1/en
Publication of UY30536A1 publication Critical patent/UY30536A1/en

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  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Sistema de liberacion farmacéutica controlada (independiente del pH) para administracion, particularmente oral, de sustancias activas con solubilidades dependientes del pH, comprendiendo material de nucleo conteniendo o consistiendo en uno o más modificadores del pH farmacéuticamente aceptables y las siguientes capas: a) opcionalmente una aislante, c) una primera comprendiendo uno o más polímeros insolubles en agua farmacéuticamente aceptables; d) una segunda comprendiendo por lo menos una sustancia activa con una solubilidad dependiente del pH; e) una tercera comprendiendo uno o más polímeros farmacéuticamente aceptables conteniendo grupos anionicos o no ionicos; y f) opcionalmente una cuarta, preferiblemente en forma de recubrimiento externo.Pharmaceutical controlled release system (independent of pH) for administration, particularly oral, of active substances with pH-dependent solubilities, comprising core material containing or consisting of one or more pharmaceutically acceptable pH modifiers and the following layers: a) optionally a insulator, c) a first comprising one or more pharmaceutically acceptable water insoluble polymers; d) a second one comprising at least one active substance with a pH dependent solubility; e) a third comprising one or more pharmaceutically acceptable polymers containing anionic or non-ionic groups; and f) optionally a fourth, preferably in the form of an external coating.

UY30536A 2007-08-13 2007-08-13 SYSTEM OF CONTROLLED PHARMACEUTICAL RELEASE, PARTICULARLY ORAL ADMINISTRATION OF ACTIVE SUBSTANCES WITH SOLUBILITIES OF PH, PREPARATION AND APPLICATION. UY30536A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
UY30536A UY30536A1 (en) 2007-08-13 2007-08-13 SYSTEM OF CONTROLLED PHARMACEUTICAL RELEASE, PARTICULARLY ORAL ADMINISTRATION OF ACTIVE SUBSTANCES WITH SOLUBILITIES OF PH, PREPARATION AND APPLICATION.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
UY30536A UY30536A1 (en) 2007-08-13 2007-08-13 SYSTEM OF CONTROLLED PHARMACEUTICAL RELEASE, PARTICULARLY ORAL ADMINISTRATION OF ACTIVE SUBSTANCES WITH SOLUBILITIES OF PH, PREPARATION AND APPLICATION.

Publications (1)

Publication Number Publication Date
UY30536A1 true UY30536A1 (en) 2008-03-31

Family

ID=39247293

Family Applications (1)

Application Number Title Priority Date Filing Date
UY30536A UY30536A1 (en) 2007-08-13 2007-08-13 SYSTEM OF CONTROLLED PHARMACEUTICAL RELEASE, PARTICULARLY ORAL ADMINISTRATION OF ACTIVE SUBSTANCES WITH SOLUBILITIES OF PH, PREPARATION AND APPLICATION.

Country Status (1)

Country Link
UY (1) UY30536A1 (en)

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20170725