|
US6096318A
(en)
|
1973-05-07 |
2000-08-01 |
The Ohio State University |
Antigenically modified HCG polypeptides
|
|
US4902506A
(en)
|
1983-07-05 |
1990-02-20 |
The University Of Rochester |
Immunogenic conjugates
|
|
GB8308235D0
(en)
|
1983-03-25 |
1983-05-05 |
Celltech Ltd |
Polypeptides
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US5158769A
(en)
|
1984-03-07 |
1992-10-27 |
New York Blood Center, Inc. |
Pre-S gene coded peptide hepatitis B immunogens, vaccines, diagnostics, and synthetic lipid vesicle carriers
|
|
US5417986A
(en)
|
1984-03-16 |
1995-05-23 |
The United States Of America As Represented By The Secretary Of The Army |
Vaccines against diseases caused by enteropathogenic organisms using antigens encapsulated within biodegradable-biocompatible microspheres
|
|
US5208036A
(en)
|
1985-01-07 |
1993-05-04 |
Syntex (U.S.A.) Inc. |
N-(ω, (ω-1)-dialkyloxy)- and N-(ω, (ω-1)-dialkenyloxy)-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor
|
|
US4666829A
(en)
|
1985-05-15 |
1987-05-19 |
University Of California |
Polypeptide marker for Alzheimer's disease and its use for diagnosis
|
|
US5618920A
(en)
|
1985-11-01 |
1997-04-08 |
Xoma Corporation |
Modular assembly of antibody genes, antibodies prepared thereby and use
|
|
EP0247091B1
(en)
|
1985-11-01 |
1993-09-29 |
Xoma Corporation |
Modular assembly of antibody genes, antibodies prepared thereby and use
|
|
US4713366A
(en)
|
1985-12-04 |
1987-12-15 |
The Ohio State University Research Foundation |
Antigenic modification of polypeptides
|
|
US5096706A
(en)
|
1986-03-25 |
1992-03-17 |
National Research Development Corporation |
Antigen-based treatment for adiposity
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
US6548640B1
(en)
|
1986-03-27 |
2003-04-15 |
Btg International Limited |
Altered antibodies
|
|
JPS62267297A
(ja)
|
1986-05-15 |
1987-11-19 |
Tokyo Met Gov Seishin Igaku Sogo Kenkyusho |
老人斑反応性モノクロ−ナル抗体、それを産生する細胞株及び該モノクロ−ナル抗体の製造方法
|
|
US5278049A
(en)
|
1986-06-03 |
1994-01-11 |
Incyte Pharmaceuticals, Inc. |
Recombinant molecule encoding human protease nexin
|
|
US5231170A
(en)
|
1986-08-27 |
1993-07-27 |
Paul Averback |
Antibodies to dense microspheres
|
|
US5223482A
(en)
|
1986-11-17 |
1993-06-29 |
Scios Nova Inc. |
Recombinant Alzheimer's protease inhibitory amyloid protein and method of use
|
|
US5220013A
(en)
|
1986-11-17 |
1993-06-15 |
Scios Nova Inc. |
DNA sequence useful for the detection of Alzheimer's disease
|
|
US5187153A
(en)
|
1986-11-17 |
1993-02-16 |
Scios Nova Inc. |
Methods of treatment using Alzheimer's amyloid polypeptide derivatives
|
|
US4879213A
(en)
|
1986-12-05 |
1989-11-07 |
Scripps Clinic And Research Foundation |
Synthetic polypeptides and antibodies related to Epstein-Barr virus early antigen-diffuse
|
|
DE3702789A1
(de)
|
1987-01-30 |
1988-08-18 |
Bayer Ag |
Vorlaeuferprotein des apc-polypeptids, dafuer codierende dna und diagnostische verwendung der dna und des proteins
|
|
US4912206A
(en)
|
1987-02-26 |
1990-03-27 |
The United States Of America As Represented By The Department Of Health And Human Services |
CDNA clone encoding brain amyloid of alzheimer's disease
|
|
AU600575B2
(en)
|
1987-03-18 |
1990-08-16 |
Sb2, Inc. |
Altered antibodies
|
|
JPS63245689A
(ja)
|
1987-03-31 |
1988-10-12 |
Suntory Ltd |
ヒトアミロイド関連蛋白モノクロ−ナル抗体
|
|
US4883666A
(en)
|
1987-04-29 |
1989-11-28 |
Massachusetts Institute Of Technology |
Controlled drug delivery system for treatment of neural disorders
|
|
US5258498A
(en)
|
1987-05-21 |
1993-11-02 |
Creative Biomolecules, Inc. |
Polypeptide linkers for production of biosynthetic proteins
|
|
US5057540A
(en)
|
1987-05-29 |
1991-10-15 |
Cambridge Biotech Corporation |
Saponin adjuvant
|
|
US5245015A
(en)
|
1991-04-26 |
1993-09-14 |
Tanox Biosystems, Inc. |
Monoclonal antibodies which neutralize HIV-1 through reaction with a conformational epitope in vitro
|
|
US5583112A
(en)
|
1987-05-29 |
1996-12-10 |
Cambridge Biotech Corporation |
Saponin-antigen conjugates and the use thereof
|
|
US5645820A
(en)
|
1987-06-24 |
1997-07-08 |
Autoimmune, Inc. |
Treatment of autoimmune diseases by aerosol administration of autoantigens
|
|
US5571499A
(en)
|
1987-06-24 |
1996-11-05 |
Autoimmune, Inc. |
Treatment of autoimmune diseases by aerosol administration of autoantigens
|
|
US5869054A
(en)
|
1987-06-24 |
1999-02-09 |
Autoimmune Inc. |
Treatment of multiple sclerosis by oral administration of autoantigens
|
|
US5641474A
(en)
|
1987-06-24 |
1997-06-24 |
Autoimmune, Inc. |
Prevention of autoimmune diseases by aerosol administration of autoantigens
|
|
US5571500A
(en)
|
1987-06-24 |
1996-11-05 |
Autoimmune, Inc. |
Treatment of autoimmune diseases through administration by inhalation of autoantigens
|
|
EP0666080B1
(en)
|
1987-06-24 |
2004-01-21 |
Brigham & Women's Hospital |
Treatment of autoimmune diseases by oral administration of autoantigens
|
|
US5849298A
(en)
|
1987-06-24 |
1998-12-15 |
Autoimmune Inc. |
Treatment of multiple sclerosis by oral administration of bovine myelin
|
|
US5004697A
(en)
|
1987-08-17 |
1991-04-02 |
Univ. Of Ca |
Cationized antibodies for delivery through the blood-brain barrier
|
|
US4966753A
(en)
|
1987-08-18 |
1990-10-30 |
Molecular Rx, Inc. |
Immunotherapeutic methods and compositions employing antigens characteristic of malignant neoplasms
|
|
US5677425A
(en)
|
1987-09-04 |
1997-10-14 |
Celltech Therapeutics Limited |
Recombinant antibody
|
|
US5231000A
(en)
|
1987-10-08 |
1993-07-27 |
The Mclean Hospital |
Antibodies to A4 amyloid peptide
|
|
CA1339014C
(en)
|
1987-10-08 |
1997-03-25 |
Ronald E. Majocha |
Antibodies to a4 amyloid peptide
|
|
WO1989003687A1
(en)
|
1987-10-23 |
1989-05-05 |
Genetics Institute, Inc. |
Composition and method for treating cancers characterized by over-expression of the c-fms proto-oncogene
|
|
US5089603A
(en)
|
1989-06-21 |
1992-02-18 |
Tanox Biosystems, Inc. |
Antigenic epitopes present on membrane-bound but not secreted iga
|
|
AU3056289A
(en)
|
1988-01-13 |
1989-08-11 |
Mclean Hospital Corporation, The |
Genetic constructs containing the alzheimer brain amyloid gene
|
|
US4912094B1
(en)
|
1988-06-29 |
1994-02-15 |
Ribi Immunochem Research Inc. |
Modified lipopolysaccharides and process of preparation
|
|
US5576184A
(en)
|
1988-09-06 |
1996-11-19 |
Xoma Corporation |
Production of chimeric mouse-human antibodies with specificity to human tumor antigens
|
|
WO1990005142A1
(en)
|
1988-11-10 |
1990-05-17 |
Imperial Cancer Research Technology Ltd. |
Polypeptides
|
|
IL162181A
(en)
|
1988-12-28 |
2006-04-10 |
Pdl Biopharma Inc |
A method of producing humanized immunoglubulin, and polynucleotides encoding the same
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5227159A
(en)
|
1989-01-31 |
1993-07-13 |
Miller Richard A |
Anti-idiotype antibodies reactive with shared idiotopes expressed by B cell lymphomas and autoantibodies
|
|
US5262332A
(en)
|
1989-04-05 |
1993-11-16 |
Brigham And Women's Hospital |
Diagnostic method for Alzheimer's disease: examination of non-neural tissue
|
|
AU5525090A
(en)
|
1989-04-14 |
1990-11-16 |
Research Foundation For Mental Hygiene, Inc. |
Monoclonal antibody to amyloid peptide
|
|
WO1990012871A1
(en)
|
1989-04-14 |
1990-11-01 |
Research Foundation For Mental Hygiene, Inc. |
Cerebrovascular amyloid protein-specific monoclonal antibody sv17-6e10
|
|
WO1990014837A1
(en)
|
1989-05-25 |
1990-12-13 |
Chiron Corporation |
Adjuvant formulation comprising a submicron oil droplet emulsion
|
|
ATE190496T1
(de)
|
1989-12-20 |
2000-04-15 |
Autoimmune Inc |
Behandlung von autoimmunkrankheiten durch verabreichung von autoantigenen in form von aerosol
|
|
GB8928874D0
(en)
|
1989-12-21 |
1990-02-28 |
Celltech Ltd |
Humanised antibodies
|
|
US5859205A
(en)
|
1989-12-21 |
1999-01-12 |
Celltech Limited |
Humanised antibodies
|
|
EP1690935A3
(en)
|
1990-01-12 |
2008-07-30 |
Abgenix, Inc. |
Generation of xenogeneic antibodies
|
|
ES2107459T3
(es)
|
1990-03-02 |
1997-12-01 |
Autoimmune Inc |
Mejora de la regulacion represora de enfermedades autoinmunes por administracion oral o enteral de autoantigenos.
|
|
EP0451700A1
(en)
|
1990-04-10 |
1991-10-16 |
Miles Inc. |
Recombinant APP minigenes for expression in transgenic mice as models for Alzheimers's disease
|
|
JPH05506990A
(ja)
|
1990-04-24 |
1993-10-14 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
プロテアーゼ ネキシン―２の精製、検出、及び使用方法
|
|
US5753624A
(en)
|
1990-04-27 |
1998-05-19 |
Milkhaus Laboratory, Inc. |
Materials and methods for treatment of plaquing disease
|
|
GB9009548D0
(en)
|
1990-04-27 |
1990-06-20 |
Celltech Ltd |
Chimeric antibody and method
|
|
JP2980677B2
(ja)
|
1990-04-27 |
1999-11-22 |
マクマイケル，ジョン |
不正常なアミロイドβタンパク質と関連する中枢神経系疾患状態の治療のための方法および組成物
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
US5387742A
(en)
|
1990-06-15 |
1995-02-07 |
Scios Nova Inc. |
Transgenic mice displaying the amyloid-forming pathology of alzheimer's disease
|
|
EP0537247A4
(en)
|
1990-06-19 |
1993-09-08 |
Immuvax |
Nonpathogenic variant virus
|
|
GB9014932D0
(en)
|
1990-07-05 |
1990-08-22 |
Celltech Ltd |
Recombinant dna product and method
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
US5780587A
(en)
|
1990-08-24 |
1998-07-14 |
President And Fellows Of Harvard College |
Compounds and methods for inhibiting β-protein filament formation and neurotoxicity
|
|
WO1993012227A1
(en)
|
1991-12-17 |
1993-06-24 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
NZ239643A
(en)
|
1990-09-17 |
1996-05-28 |
North American Vaccine Inc |
Vaccine containing bacterial polysaccharide protein conjugate and adjuvant (c-nd-che-a-co-b-r) with a long chain alkyl group.
|
|
US5702906A
(en)
|
1990-09-25 |
1997-12-30 |
Genentech, Inc. |
Antibodies to neurotrophic factor-4 (NT-4)
|
|
JPH06502071A
(ja)
|
1990-09-28 |
1994-03-10 |
ジ・アップジョン・カンパニー |
アルツハイマーのアミロイド前駆遺伝子を有するトランスジェニック動物
|
|
EP0553244B8
(en)
|
1990-10-05 |
2005-06-08 |
Celldex Therapeutics, Inc. |
Targeted immunostimulation with bispecific reagents
|
|
AU9023791A
(en)
|
1990-10-15 |
1992-05-20 |
Brigham And Women's Hospital |
Treatment of autoimmune diseases by oral administration of autoantigens
|
|
GB9023352D0
(en)
|
1990-10-26 |
1990-12-05 |
Lynxvale Ltd |
Vaccinia vectors,vaccinia genes and expression products thereof
|
|
US5877015A
(en)
|
1991-01-21 |
1999-03-02 |
Imperial College Of Science, Technology Of Medicine |
APP770 mutant in alzheimer's disease
|
|
EP0501882B1
(fr)
|
1991-03-01 |
2000-07-12 |
Merial |
Procédé d'immunoneutralisation anti-LHRM des animaux domestiques mâles non castrés et peptide pour cela
|
|
US5192753A
(en)
|
1991-04-23 |
1993-03-09 |
Mcgeer Patrick L |
Anti-rheumatoid arthritic drugs in the treatment of dementia
|
|
EP0538437B1
(en)
|
1991-05-08 |
1999-08-04 |
SCHWEIZ. SERUM- & IMPFINSTITUT BERN |
Immunostimulating and immunopotentiating reconstituted influenza virosomes and vaccines containing them
|
|
WO1994004679A1
(en)
|
1991-06-14 |
1994-03-03 |
Genentech, Inc. |
Method for making humanized antibodies
|
|
WO1992022653A1
(en)
|
1991-06-14 |
1992-12-23 |
Genentech, Inc. |
Method for making humanized antibodies
|
|
US5672805A
(en)
|
1991-07-18 |
1997-09-30 |
The Regents Of The University Of California |
Transgenic mice expressing the neurotoxic C-terminus of β-amyloid precursor protein
|
|
JP2966592B2
(ja)
|
1991-07-20 |
1999-10-25 |
萩原 義秀 |
安定化されたヒトモノクローナル抗体製剤
|
|
US5434050A
(en)
|
1991-08-13 |
1995-07-18 |
Regents Of The University Of Minnesota |
Labelled β-amyloid peptide and methods of screening for Alzheimer's disease
|
|
US5837268A
(en)
|
1991-10-16 |
1998-11-17 |
University Of Saskatchewan |
GnRH-leukotoxin chimeras
|
|
WO1993014200A1
(en)
|
1992-01-07 |
1993-07-22 |
Tsi Corporation |
Transgenic animal models for alzheimer's disease
|
|
US5679348A
(en)
|
1992-02-03 |
1997-10-21 |
Cedars-Sinai Medical Center |
Immunotherapy for recurrent HSV infections
|
|
EP1958646A1
(en)
|
1992-02-11 |
2008-08-20 |
Henry M. Jackson Foundation For The Advancement Of Military Medicine |
Dual carrier immunogenic construct
|
|
DE69332518T2
(de)
|
1992-02-28 |
2003-09-04 |
Autoimmune Inc |
Unterdrückung von autoimmunkrankheiten durch antigene in wartestellung
|
|
US5714350A
(en)
|
1992-03-09 |
1998-02-03 |
Protein Design Labs, Inc. |
Increasing antibody affinity by altering glycosylation in the immunoglobulin variable region
|
|
EP0561087B1
(en)
|
1992-03-20 |
1999-08-04 |
N.V. Innogenetics S.A. |
Mutated form of the beta-amyloid precursor protein gene
|
|
US5441870A
(en)
|
1992-04-15 |
1995-08-15 |
Athena Neurosciences, Inc. |
Methods for monitoring cellular processing of β-amyloid precursor protein
|
|
US5604102A
(en)
|
1992-04-15 |
1997-02-18 |
Athena Neurosciences, Inc. |
Methods of screening for β-amyloid peptide production inhibitors
|
|
US5851787A
(en)
|
1992-04-20 |
1998-12-22 |
The General Hospital Corporation |
Nucleic acid encoding amyloid precursor-like protein and uses thereof
|
|
AU4116793A
(en)
|
1992-04-24 |
1993-11-29 |
Board Of Regents, The University Of Texas System |
Recombinant production of immunoglobulin-like domains in prokaryotic cells
|
|
GB9209118D0
(en)
|
1992-04-28 |
1992-06-10 |
Sb 120 Amsterdam Bv |
Vaccine compositions
|
|
ES2142346T3
(es)
|
1992-06-18 |
2000-04-16 |
Harvard College |
Adn, polipeptido, celula, composicion y vacunas contra la toxina de la difteria.
|
|
SG90042A1
(en)
|
1992-06-25 |
2002-07-23 |
Smithkline Beecham Biolog |
Vaccine composition containing adjuvants
|
|
US5766846A
(en)
|
1992-07-10 |
1998-06-16 |
Athena Neurosciences |
Methods of screening for compounds which inhibit soluble β-amyloid peptide production
|
|
US6610493B1
(en)
|
1993-06-17 |
2003-08-26 |
Brigham And Women's Hospital |
Screening compounds for the ability to alter the production of amyloid-β peptide
|
|
US5837672A
(en)
|
1992-07-10 |
1998-11-17 |
Athena Neurosciences, Inc. |
Methods and compositions for the detection of soluble β-amyloid peptide
|
|
WO1994001772A1
(en)
|
1992-07-13 |
1994-01-20 |
The Children's Medical Center Corporation |
SCREEN FOR ALZHEIMER'S DISEASE THERAPEUTICS BASED ON β-AMYLOID PRODUCTION
|
|
IL102687A
(en)
|
1992-07-30 |
1997-06-10 |
Yeda Res & Dev |
Conjugates of poorly immunogenic antigens and synthetic pepide carriers and vaccines comprising them
|
|
AU4719393A
(en)
|
1992-07-31 |
1994-03-03 |
Medeva Holdings B.V. |
Expression of recombinant fusion proteins in attenuated bacteria
|
|
WO1994005311A1
(en)
|
1992-08-27 |
1994-03-17 |
Deakin Research Limited |
Retro-, inverso-, and retro-inverso synthetic peptide analogues
|
|
US5958883A
(en)
|
1992-09-23 |
1999-09-28 |
Board Of Regents Of The University Of Washington Office Of Technology |
Animal models of human amyloidoses
|
|
AU5358494A
(en)
|
1992-10-13 |
1994-05-09 |
Duke University |
Method of inhibiting binding of amyloid precursor protein to beta-amyloid protein
|
|
US5605811A
(en)
|
1992-10-26 |
1997-02-25 |
Athena Neurosciences, Inc. |
Methods and compositions for monitoring cellular processing of beta-amyloid precursor protein
|
|
DE667959T1
(de)
|
1992-10-26 |
2000-04-20 |
Dale B Schenk |
VERFAHREN UND ZUSAMMENSETZUNGEN FÜR DEN NACHWEIS VON LÖSLICHEM-g(b)-AMYLOIDPEPTID.
|
|
US5972336A
(en)
|
1992-11-03 |
1999-10-26 |
Oravax Merieux Co. |
Urease-based vaccine against helicobacter infection
|
|
US6210671B1
(en)
|
1992-12-01 |
2001-04-03 |
Protein Design Labs, Inc. |
Humanized antibodies reactive with L-selectin
|
|
ATE372783T1
(de)
|
1993-01-22 |
2007-09-15 |
Sloan Kettering Inst Cancer |
Gangliosid-klh-konjugatimpfstoffe mit qs-21 zur verzögerung des wiederauftretens eines melanoms
|
|
US5955317A
(en)
|
1993-01-25 |
1999-09-21 |
Takeda Chemical Industries, Ltd. |
Antibodies to β-amyloids or their derivatives and use thereof
|
|
WO1994017197A1
(fr)
|
1993-01-25 |
1994-08-04 |
Takeda Chemical Industries, Ltd. |
ANTICORPS DIRIGE CONTRE LE β-AMYLOIDE OU UN DERIVE DE CE DERNIER ET SON UTILISATION
|
|
US5358708A
(en)
|
1993-01-29 |
1994-10-25 |
Schering Corporation |
Stabilization of protein formulations
|
|
US5472693A
(en)
|
1993-02-16 |
1995-12-05 |
The Dow Chemical Company |
Family of anti-carcinoembryonic antigen chimeric antibodies
|
|
DE614989T1
(de)
|
1993-02-17 |
1995-09-28 |
Morphosys Proteinoptimierung |
Verfahren für in vivo Selektion von Ligandenbindende Proteine.
|
|
CA2115900A1
(en)
|
1993-02-22 |
1994-08-23 |
Gerald W. Becker |
Pharmaceutical screens and antibodies
|
|
CA2158455C
(en)
|
1993-03-17 |
2003-05-27 |
Nicholas P. Restifo |
Immunogenic chimeras comprising nucleic acid sequences encoding endoplasmic reticulum signal sequence peptides and at least one other peptide and their uses in vaccines and disease treatments
|
|
ATE270111T1
(de)
|
1993-03-18 |
2004-07-15 |
Cytimmune Sciences Inc |
Zusammensetzung und methode zur reduktion der toxizität von biologisch-aktiven faktoren
|
|
ATE204762T1
(de)
|
1993-03-23 |
2001-09-15 |
Smithkline Beecham Biolog |
3-0-deazylierte monophosphoryl lipid a enthaltende impfstoff-zusammensetzungen
|
|
CA2119090A1
(en)
|
1993-03-26 |
1994-09-27 |
Wayne R. Gombotz |
Compositions for controlled release of biologically active tgf-.beta.
|
|
IT1270939B
(it)
|
1993-05-11 |
1997-05-26 |
Angeletti P Ist Richerche Bio |
Procedimento per la preparazione di immunogeni e reagenti diagnostici,e immunogeni e reagenti diagnostici cosi' ottenibili.
|
|
CA2163550A1
(en)
|
1993-05-25 |
1994-12-08 |
Gerald E. Hancock |
Adjuvants for vaccines against respiratory syncytial virus
|
|
WO1994028412A1
(en)
|
1993-05-28 |
1994-12-08 |
The Miriam Hospital |
Composition and method for in vivo imaging of amyloid deposits
|
|
EP1221488A1
(en)
|
1993-06-04 |
2002-07-10 |
Whitehead Institute For Biomedical Research |
Stress proteins and uses therefor
|
|
US5464823A
(en)
|
1993-07-20 |
1995-11-07 |
The Regents Of The University Of California |
Mammalian antibiotic peptides
|
|
CA2168459C
(en)
|
1993-07-30 |
2002-10-01 |
Mohammed Anjam Khan |
Fusion proteins containing the c-terminal of tetanus toxin linked to a heterologous protein
|
|
WO1995005393A2
(en)
|
1993-08-18 |
1995-02-23 |
Morphosys Gesellschaft Für Proteinoptimierung Mbh |
Lipopolysaccharide-binding and neutralizing peptides
|
|
AU707083B2
(en)
|
1993-08-26 |
1999-07-01 |
Bavarian Nordic Inc. |
Inducing antibody response against self-proteins with the aid of foreign T-cell epitopes
|
|
WO1995005853A1
(en)
|
1993-08-26 |
1995-03-02 |
The Regents Of The University Of California |
Method, compositions and devices for administration of naked polynucleotides which encode biologically active peptides
|
|
DK96493D0
(da)
|
1993-08-26 |
1993-08-26 |
Mouritsen Og Elsner Aps |
Fremgangsmaade til at inducere antistofresponser mod selvproteiner og autovaccine fremstillet ved fremgangsmaaden
|
|
WO1995006407A1
(en)
|
1993-08-30 |
1995-03-09 |
The Regents Of The University Of California |
Novel component of amyloid in alzheimer's disease and methods for use of same
|
|
WO1995007301A1
(en)
|
1993-09-07 |
1995-03-16 |
Smithkline Beecham Corporation |
Recombinant il4 antibodies useful in treatment of il4 mediated disorders
|
|
US5652334A
(en)
|
1993-09-08 |
1997-07-29 |
City Of Hope |
Method for design of substances that enhance memory and improve the quality of life
|
|
US5385887A
(en)
|
1993-09-10 |
1995-01-31 |
Genetics Institute, Inc. |
Formulations for delivery of osteogenic proteins
|
|
WO1995007707A1
(en)
|
1993-09-14 |
1995-03-23 |
Cytel Corporation |
Alteration of immune response using pan dr-binding peptides
|
|
US5470951A
(en)
|
1993-09-29 |
1995-11-28 |
City Of Hope |
Peptides for antagonizing the effects of amyloid βprotein
|
|
US5858981A
(en)
|
1993-09-30 |
1999-01-12 |
University Of Pennsylvania |
Method of inhibiting phagocytosis
|
|
JPH09506170A
(ja)
|
1993-10-20 |
1997-06-17 |
デューク・ユニヴァーシティ |
β‐アミロイドペプチドに物質を結合する方法
|
|
JP3504963B2
(ja)
|
1993-10-22 |
2004-03-08 |
智靖 羅 |
抗ヒト高親和性ＩｇＥ受容体モノクローナル抗体に係るアミノ酸配列をコードするＤＮＡ断片
|
|
ATE223702T1
(de)
|
1993-10-22 |
2002-09-15 |
Genentech Inc |
Verfahren und zusammensetzungen zur mikrokapselung von adjuvantien
|
|
US5744368A
(en)
|
1993-11-04 |
1998-04-28 |
Research Foundation Of State University Of New York |
Methods for the detection of soluble amyloid β-protein (βAP) or soluble transthyretin (TTR)
|
|
JPH07132033A
(ja)
|
1993-11-12 |
1995-05-23 |
Hoechst Japan Ltd |
アルツハイマー病モデルトランスジェニック動物
|
|
US5827690A
(en)
|
1993-12-20 |
1998-10-27 |
Genzyme Transgenics Corporatiion |
Transgenic production of antibodies in milk
|
|
GB9326253D0
(en)
|
1993-12-23 |
1994-02-23 |
Smithkline Beecham Biolog |
Vaccines
|
|
US5434170A
(en)
|
1993-12-23 |
1995-07-18 |
Andrulis Pharmaceuticals Corp. |
Method for treating neurocognitive disorders
|
|
US5877399A
(en)
|
1994-01-27 |
1999-03-02 |
Johns Hopkins University |
Transgenic mice expressing APP-Swedish mutation develop progressive neurologic disease
|
|
ATE278023T1
(de)
|
1994-01-27 |
2004-10-15 |
Univ Minnesota |
Nicht humane, transgenische säugetiere mit sich entwickelnder neurologischer krankheit
|
|
WO1995020979A1
(en)
|
1994-02-03 |
1995-08-10 |
The Picower Institute For Medical Research |
Compositions and methods for advanced glycosylation endproduct-mediated modulation of amyloidosis
|
|
AUPM411994A0
(en)
|
1994-02-25 |
1994-03-24 |
Deakin Research Limited |
Epitopes
|
|
US5795954A
(en)
|
1994-03-04 |
1998-08-18 |
Genentech, Inc. |
Factor VIIa inhibitors from Kunitz domain proteins
|
|
US6270757B1
(en)
|
1994-04-21 |
2001-08-07 |
Genetics Institute, Inc. |
Formulations for IL-11
|
|
US6372716B1
(en)
|
1994-04-26 |
2002-04-16 |
Genetics Institute, Inc. |
Formulations for factor IX
|
|
JP3064013B2
(ja)
|
1994-05-25 |
2000-07-12 |
ジョン マクマイケル， |
斑形成疾患の治療のための方法及び材料
|
|
US5622701A
(en)
|
1994-06-14 |
1997-04-22 |
Protein Design Labs, Inc. |
Cross-reacting monoclonal antibodies specific for E- and P-selectin
|
|
US5798100A
(en)
|
1994-07-06 |
1998-08-25 |
Immunomedics, Inc. |
Multi-stage cascade boosting vaccine
|
|
US6417178B1
(en)
|
1994-07-19 |
2002-07-09 |
University Of Pittsburgh |
Amyloid binding nitrogen-linked compounds for the antemortem diagnosis of alzheimer's disease, in vivo imaging and prevention of amyloid deposits
|
|
JPH10506004A
(ja)
|
1994-07-27 |
1998-06-16 |
ザ カウンシル オブ ザ クィーンズランド インスティテュート オブ メディカル リサーチ |
ポリエピトープワクチン
|
|
US5872005A
(en)
|
1994-11-03 |
1999-02-16 |
Cell Genesys Inc. |
Packaging cell lines for adeno-associated viral vectors
|
|
US6114133A
(en)
|
1994-11-14 |
2000-09-05 |
Elan Pharmaceuticals, Inc. |
Methods for aiding in the diagnosis of Alzheimer's disease by measuring amyloid-β peptide (x-≧41)
|
|
US5589154A
(en)
|
1994-11-22 |
1996-12-31 |
Rutgers, The State University Of New Jersey |
Methods for the prevention or treatment of vascular hemorrhaging and Alzheimer's disease
|
|
US5688651A
(en)
|
1994-12-16 |
1997-11-18 |
Ramot University Authority For Applied Research And Development Ltd. |
Prevention of protein aggregation
|
|
ATE216590T1
(de)
|
1995-02-06 |
2002-05-15 |
Genetics Inst |
Arzneimittelformulierungen für il-12
|
|
US5786180A
(en)
|
1995-02-14 |
1998-07-28 |
Bayer Corporation |
Monoclonal antibody 369.2B specific for β A4 peptide
|
|
US5624937A
(en)
|
1995-03-02 |
1997-04-29 |
Eli Lilly And Company |
Chemical compounds as inhibitors of amyloid beta protein production
|
|
US5854215A
(en)
|
1995-03-14 |
1998-12-29 |
Praecis Pharmaceuticals Incorporated |
Modulators of β-amyloid peptide aggregation
|
|
US5817626A
(en)
|
1995-03-14 |
1998-10-06 |
Praecis Pharmaceuticals Incorporated |
Modulators of beta-amyloid peptide aggregation
|
|
ATE218583T1
(de)
|
1995-03-14 |
2002-06-15 |
Praecis Pharm Inc |
Verbindungen mit aggregations-modulierenden wirkung auf das amyloid protein
|
|
US6303567B1
(en)
|
1995-03-14 |
2001-10-16 |
Praecis Pharmaceuticals, Inc . |
Modulators of β-amyloid peptide aggregation comprising D-amino acids
|
|
JPH11502222A
(ja)
|
1995-03-23 |
1999-02-23 |
キャンタブ ファーマシューティカルズ リサーチ リミティド |
遺伝子供給用ベクター
|
|
US6121022A
(en)
|
1995-04-14 |
2000-09-19 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
|
US5869046A
(en)
|
1995-04-14 |
1999-02-09 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
|
UA56132C2
(uk)
|
1995-04-25 |
2003-05-15 |
Смітклайн Бічем Байолоджікалс С.А. |
Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини
|
|
JPH11508126A
(ja)
|
1995-05-23 |
1999-07-21 |
モルフォシス ゲゼルシャフト ファー プロテインオプティマイルング エムベーハー |
多量体タンパク質
|
|
WO1996039176A1
(en)
|
1995-06-05 |
1996-12-12 |
Brigham & Women's Hospital |
USE OF ORAL TOLERANCE TO SUPPRESS BOTH Th1 AND Th2 IMMUNE RESPONSES AND TO SUPPRESS ANTIBODY PRODUCTION
|
|
AU6264996A
(en)
|
1995-06-07 |
1996-12-30 |
Athena Neurosciences, Inc. |
Method for identifying alzheimer's disease therapeutics usin g transgenic animal models
|
|
US5948763A
(en)
|
1995-06-07 |
1999-09-07 |
New York University |
Peptides and pharmaceutical compositions thereof for treatment of disorders or diseases associated with abnormal protein folding into amyloid or amyloid-like deposits
|
|
US5910427A
(en)
|
1995-06-22 |
1999-06-08 |
La Jolla Institute For Allergy And Immunology |
Antigen non-specific glycosylation inhibiting factor derivatives
|
|
DK0750907T3
(da)
|
1995-06-30 |
2002-07-08 |
American Cyanamid Co |
Stabile vaccinepræparater til parenteral administrering, en fremgangsmåde til deres anvendelse og en fremgangsmåde til deres fremstilling
|
|
ATE305039T1
(de)
|
1995-07-07 |
2005-10-15 |
Darwin Molecular Corp |
Auf chromosom 1 lokalisiertes gen dessen genprodukt mit der alzheimerschen krankheit assoziiert ist.
|
|
US6685940B2
(en)
|
1995-07-27 |
2004-02-03 |
Genentech, Inc. |
Protein formulation
|
|
AUPN443995A0
(en)
|
1995-07-27 |
1995-08-17 |
Csl Limited |
Papillomavirus polyprotein
|
|
US6267958B1
(en)
|
1995-07-27 |
2001-07-31 |
Genentech, Inc. |
Protein formulation
|
|
JP4436457B2
(ja)
|
1995-08-18 |
2010-03-24 |
モルフォシス アイピー ゲーエムベーハー |
蛋白質／（ポリ）ペプチドライブラリー
|
|
US5824322A
(en)
|
1995-08-21 |
1998-10-20 |
Cytrx Corporation |
Compositions and methods for growth promotion
|
|
BR9610580A
(pt)
|
1995-09-14 |
2000-10-24 |
Univ California |
Anticorpos especìficos para prpse nativos
|
|
US5731284A
(en)
|
1995-09-28 |
1998-03-24 |
Amgen Inc. |
Method for treating Alzheimer's disease using glial line-derived neurotrophic factor (GDNF) protein product
|
|
AU3804995A
(en)
|
1995-10-10 |
1997-04-30 |
Novartis Ag |
Melanoma-associated protein
|
|
US5985242A
(en)
|
1995-10-27 |
1999-11-16 |
Praecis Pharmaceuticals, Inc. |
Modulators of β-amyloid peptide aggregation comprising D-amino acids
|
|
US5750361A
(en)
|
1995-11-02 |
1998-05-12 |
The Regents Of The University Of California |
Formation and use of prion protein (PRP) complexes
|
|
EP1281718A3
(en)
|
1995-11-10 |
2005-01-19 |
ELAN CORPORATION, Plc |
Peptides which enhance transport across tissues
|
|
WO1997018855A1
(en)
|
1995-11-21 |
1997-05-29 |
Eduard Naumovich Lerner |
Device for enhanced delivery of biologically active substances and compounds in an organism
|
|
WO1997021728A1
(en)
|
1995-12-12 |
1997-06-19 |
Karolinska Innovations Ab |
PEPTIDE BINDING THE KLVFF-SEQUENCE OF AMYLOID $g(b)
|
|
JPH09178743A
(ja)
|
1995-12-27 |
1997-07-11 |
Oriental Yeast Co Ltd |
可溶性ａｐｐの定量法
|
|
US6015662A
(en)
|
1996-01-23 |
2000-01-18 |
Abbott Laboratories |
Reagents for use as calibrators and controls
|
|
ZA97452B
(en)
|
1996-01-25 |
1997-08-15 |
Trinity College Dublin |
Streptococcus equi vaccine.
|
|
US5770700A
(en)
|
1996-01-25 |
1998-06-23 |
Genetics Institute, Inc. |
Liquid factor IX formulations
|
|
WO1997026913A1
(en)
|
1996-01-26 |
1997-07-31 |
The Trustees Of Columbia University In The City Of New York |
A POLYPEPTIDE FROM LUNG EXTRACT WHICH BINDS AMYLOID-β PEPTIDE
|
|
JPH09208485A
(ja)
|
1996-01-31 |
1997-08-12 |
Teijin Ltd |
ペプチド・蛋白質性薬物の水難溶性組成物
|
|
US6096313A
(en)
|
1996-02-09 |
2000-08-01 |
Ludwig Institute For Cancer Research |
Compositions containing immunogenic molecules and granulocyte-macrophage colony stimulating factor, as an adjuvant
|
|
EP0883686A1
(en)
|
1996-02-26 |
1998-12-16 |
Morphosys Gesellschaft für Proteinoptimierung mbH |
Novel method for the identification of nucleic acid sequences encoding two or more interacting (poly)peptides
|
|
US6150091A
(en)
|
1996-03-06 |
2000-11-21 |
Baylor College Of Medicine |
Direct molecular diagnosis of Friedreich ataxia
|
|
JP4229341B2
(ja)
|
1996-03-23 |
2009-02-25 |
財団法人阪大微生物病研究会 |
破傷風毒素の機能的フラグメント抗原及び破傷風ワクチン
|
|
CA2250041A1
(en)
|
1996-03-29 |
1997-10-09 |
University Of Otago |
Parapoxvirus vectors
|
|
AU713067B2
(en)
|
1996-04-03 |
1999-11-25 |
Anergen, Inc. |
Cyclic peptide vaccines for treatment and prevention of diabetes
|
|
US6838237B2
(en)
|
1996-04-19 |
2005-01-04 |
The United States Of America As Represented By The Department Of Health And Human Services |
Antigenically reactive regions of the hepatitis a virus polyprotein
|
|
US6284533B1
(en)
|
1996-05-01 |
2001-09-04 |
Avant Immunotherapeutics, Inc. |
Plasmid-based vaccine for treating atherosclerosis
|
|
JP2000516452A
(ja)
|
1996-07-16 |
2000-12-12 |
プリュックテュン，アンドレアス |
可溶性が増大した免疫グロブリンスーパーファミリードメインおよびフラグメント
|
|
EP0960204A4
(en)
|
1996-07-26 |
2002-01-23 |
Sloan Kettering Inst Cancer |
METHODS AND REAGENTS FOR GENETIC IMMUNIZATION
|
|
US7147851B1
(en)
|
1996-08-15 |
2006-12-12 |
Millennium Pharmaceuticals, Inc. |
Humanized immunoglobulin reactive with α4β7 integrin
|
|
CA2183901A1
(en)
|
1996-08-22 |
1998-02-23 |
Johanna E. Bergmann |
Targets for therapy and diagnosis of alzheimer's disease and down syndrome in humans
|
|
AU741199B2
(en)
|
1996-08-27 |
2001-11-22 |
Praecis Pharmaceuticals Incorporated |
Modulators of beta-amyloid peptide aggregation comprising D-amino acids
|
|
US6057367A
(en)
|
1996-08-30 |
2000-05-02 |
Duke University |
Manipulating nitrosative stress to kill pathologic microbes, pathologic helminths and pathologically proliferating cells or to upregulate nitrosative stress defenses
|
|
US6797495B2
(en)
|
1996-11-05 |
2004-09-28 |
The Regents Of The University Of California |
Somatic cells with ablated PrP gene and methods of use
|
|
US6022859A
(en)
|
1996-11-15 |
2000-02-08 |
Wisconsin Alumni Research Foundation |
Inhibitors of β-amyloid toxicity
|
|
AU5508798A
(en)
|
1996-11-19 |
1998-06-10 |
Trustees Of The University Of Pennsylvania, The |
Diagnostic and therapeutic reagents for alzheimer's disease
|
|
US6962984B2
(en)
|
1996-12-05 |
2005-11-08 |
Nihon University |
IgA nephropathy-related DNA
|
|
US20030068316A1
(en)
|
1997-02-05 |
2003-04-10 |
Klein William L. |
Anti-ADDL antibodies and uses thereof
|
|
US6218506B1
(en)
|
1997-02-05 |
2001-04-17 |
Northwestern University |
Amyloid β protein (globular assembly and uses thereof)
|
|
US6277375B1
(en)
|
1997-03-03 |
2001-08-21 |
Board Of Regents, The University Of Texas System |
Immunoglobulin-like domains with increased half-lives
|
|
CA2278547A1
(en)
|
1997-03-03 |
1998-09-11 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Small molecules useful in the treatment of inflammatory disease
|
|
US5798102A
(en)
|
1997-03-04 |
1998-08-25 |
Milkhaus Laboratory, Inc. |
Treatment of cardiomyopathy
|
|
US6057098A
(en)
|
1997-04-04 |
2000-05-02 |
Biosite Diagnostics, Inc. |
Polyvalent display libraries
|
|
US8173127B2
(en)
|
1997-04-09 |
2012-05-08 |
Intellect Neurosciences, Inc. |
Specific antibodies to amyloid beta peptide, pharmaceutical compositions and methods of use thereof
|
|
EP2305709A1
(en)
|
1997-04-09 |
2011-04-06 |
Intellect Neurosciences, Inc. |
Recombinant antibodies specific for beta-amyloid ends, DNA encoding and methods for use thereof
|
|
US20020086847A1
(en)
|
1997-04-09 |
2002-07-04 |
Mindset Biopharmaceuticals (Usa) |
Recombinant antibodies specific for beta-amyloid ends, DNA encoding and methods of use thereof
|
|
CA2289476A1
(en)
|
1997-04-15 |
1998-10-22 |
Farmaceutisk Laboratorium Ferring A/S |
Modified tnf.alpha. molecules, dna encoding such modified tnf.alpha. molecules and vaccines comprising such modified tnf.alpha. molecules and dna
|
|
US6787319B2
(en)
|
1997-04-16 |
2004-09-07 |
American Home Products Corp. |
β-amyloid peptide-binding proteins and polynucleotides encoding the same
|
|
WO1998052581A1
(en)
|
1997-05-20 |
1998-11-26 |
Ottawa Civic Hospital Loeb Research Institute |
Vectors and methods for immunization or therapeutic protocols
|
|
EP0999853B1
(en)
|
1997-06-13 |
2003-01-02 |
Genentech, Inc. |
Stabilized antibody formulation
|
|
AU8269898A
(en)
|
1997-06-27 |
1999-01-19 |
Regents Of The University Of California, The |
Drug targeting of a peptide radiopharmaceutical through the primate blood-brain barrier in vivo with a monoclonal antibody to the human insulin receptor
|
|
IT1293511B1
(it)
|
1997-07-30 |
1999-03-01 |
Gentili Ist Spa |
Anticorpi monoclonali catalitici ad attivita' proteasica per la lisi selettiva della componente proteica di placche e aggregati correlati
|
|
CA2297070A1
(en)
|
1997-08-01 |
1999-02-11 |
Morphosys Ag |
Novel method and phage for the identification of nucleic acid sequences encoding members of a multimeric (poly)peptide complex
|
|
EP1001987B1
(en)
|
1997-08-01 |
2010-12-15 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Composition and method for the detection of diseases associated with amyloid-like fibril or protein aggregate formation
|
|
US6645495B1
(en)
|
1997-08-29 |
2003-11-11 |
Antigenics, Inc. |
Compositions of saponin adjuvants and excipients
|
|
US6175057B1
(en)
|
1997-10-08 |
2001-01-16 |
The Regents Of The University Of California |
Transgenic mouse model of alzheimer's disease and cerebral amyloid angiopathy
|
|
EP0921189B1
(en)
|
1997-11-14 |
2005-01-12 |
Sankyo Company Limited |
Transgenic animal allergy models and methods for their use
|
|
US6710226B1
(en)
|
1997-12-02 |
2004-03-23 |
Neuralab Limited |
Transgenic mouse assay to determine the effect of Aβ antibodies and Aβ Fragments on alzheimer's disease characteristics
|
|
US6761888B1
(en)
|
2000-05-26 |
2004-07-13 |
Neuralab Limited |
Passive immunization treatment of Alzheimer's disease
|
|
US6905686B1
(en)
|
1997-12-02 |
2005-06-14 |
Neuralab Limited |
Active immunization for treatment of alzheimer's disease
|
|
US6750324B1
(en)
|
1997-12-02 |
2004-06-15 |
Neuralab Limited |
Humanized and chimeric N-terminal amyloid beta-antibodies
|
|
US7179892B2
(en)
|
2000-12-06 |
2007-02-20 |
Neuralab Limited |
Humanized antibodies that recognize beta amyloid peptide
|
|
US7790856B2
(en)
|
1998-04-07 |
2010-09-07 |
Janssen Alzheimer Immunotherapy |
Humanized antibodies that recognize beta amyloid peptide
|
|
US20080050367A1
(en)
|
1998-04-07 |
2008-02-28 |
Guriq Basi |
Humanized antibodies that recognize beta amyloid peptide
|
|
US6923964B1
(en)
|
1997-12-02 |
2005-08-02 |
Neuralab Limited |
Active immunization of AScr for prion disorders
|
|
US6787523B1
(en)
|
1997-12-02 |
2004-09-07 |
Neuralab Limited |
Prevention and treatment of amyloidogenic disease
|
|
US6913745B1
(en)
|
1997-12-02 |
2005-07-05 |
Neuralab Limited |
Passive immunization of Alzheimer's disease
|
|
US7964192B1
(en)
|
1997-12-02 |
2011-06-21 |
Janssen Alzheimer Immunotherapy |
Prevention and treatment of amyloidgenic disease
|
|
TWI239847B
(en)
|
1997-12-02 |
2005-09-21 |
Elan Pharm Inc |
N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease
|
|
HUP0004821A2
(hu)
|
1997-12-03 |
2001-06-28 |
Fujisawa Pharmaceutical Co., Ltd. |
Lágy pellet alakjában lévő gyógyszerkészítmény és előállítása
|
|
DE1033998T1
(de)
|
1997-12-03 |
2001-05-23 |
Brigham And Women's Hospital, Boston |
Methode zur unterdrückung von beta-amyloid-verwandten veränderungen in alzheimer
|
|
FR2777015B3
(fr)
|
1998-02-23 |
2000-09-15 |
Financ De Biotechnologie |
Procede et moyens pour l'obtention de modeles cellulaires et animaux de maladies neurodegeneratives
|
|
US6194551B1
(en)
|
1998-04-02 |
2001-02-27 |
Genentech, Inc. |
Polypeptide variants
|
|
US6528624B1
(en)
|
1998-04-02 |
2003-03-04 |
Genentech, Inc. |
Polypeptide variants
|
|
US20050059591A1
(en)
|
1998-04-07 |
2005-03-17 |
Neuralab Limited |
Prevention and treatment of amyloidogenic disease
|
|
US20050059802A1
(en)
|
1998-04-07 |
2005-03-17 |
Neuralab Ltd |
Prevention and treatment of amyloidogenic disease
|
|
DE69920897T2
(de)
|
1998-04-28 |
2005-10-13 |
Smithkline Beecham Corp. |
Monoklonale antikörper mit verringerter immunisierungsfähigkeit
|
|
NO314086B1
(no)
|
1998-05-08 |
2003-01-27 |
Gemvax As |
Peptider og farmasöytiske sammensetninger inneholdende disse, nukleinsyresekvenser som koder for slike peptider, plasmider og virusvektoreromfattende slike DNA-sekvenser samt anvendelse av disse for fremstilling avfarmasöytiske preparater til
|
|
CA2328612A1
(en)
|
1998-05-19 |
1999-11-25 |
Yeda Research And Development Co., Ltd. |
Activated t cells, nervous system-specific antigens and their uses
|
|
US20030147882A1
(en)
|
1998-05-21 |
2003-08-07 |
Alan Solomon |
Methods for amyloid removal using anti-amyloid antibodies
|
|
IL139095A0
(en)
|
1998-05-21 |
2001-11-25 |
Univ Tennessee Res Corp |
Methods for amyloid removal using anti-amyloid antibodies
|
|
US6432710B1
(en)
|
1998-05-22 |
2002-08-13 |
Isolagen Technologies, Inc. |
Compositions for regenerating tissue that has deteriorated, and methods for using such compositions
|
|
US6727349B1
(en)
|
1998-07-23 |
2004-04-27 |
Millennium Pharmaceuticals, Inc. |
Recombinant anti-CCR2 antibodies and methods of use therefor
|
|
JP2002526419A
(ja)
|
1998-10-05 |
2002-08-20 |
ファーメクサ エイ／エス |
治療上のワクチン注射のための新規な方法
|
|
WO2000023082A1
(en)
|
1998-10-19 |
2000-04-27 |
Yeda Research And Development Co. Ltd. |
Treatment of systemic lupus erythematosus by down-regulating the autoimmune response to autoantigens
|
|
US7112661B1
(en)
|
1998-10-30 |
2006-09-26 |
The Research Foundation Of State University Of New York |
Variable heavy chain and variable light chain regions of antibodies to human platelet glycoprotein Ib alpha
|
|
GB2348203B
(en)
|
1998-11-04 |
2002-06-19 |
Imp College Innovations Ltd |
Solube beta-forms of prion proteins, methods of preparation and use
|
|
EP1148891B1
(en)
|
1999-01-19 |
2004-03-17 |
PHARMACIA & UPJOHN COMPANY |
Method of packaging an oxidation sensitive medicinal substance
|
|
CA2361124A1
(en)
|
1999-01-22 |
2000-07-27 |
Matthew John During |
Vaccine-mediated treatment of neurological disorders
|
|
US7629311B2
(en)
|
1999-02-24 |
2009-12-08 |
Edward Lewis Tobinick |
Methods to facilitate transmission of large molecules across the blood-brain, blood-eye, and blood-nerve barriers
|
|
US7282570B2
(en)
|
1999-04-20 |
2007-10-16 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
|
JP2003503312A
(ja)
|
1999-05-05 |
2003-01-28 |
ニューロシェム インコーポレイテッド |
立体選択的抗原線維形成ペプチドおよびそのペプチド模倣体
|
|
US6787637B1
(en)
|
1999-05-28 |
2004-09-07 |
Neuralab Limited |
N-Terminal amyloid-β antibodies
|
|
AR024558A1
(es)
|
1999-06-01 |
2002-10-16 |
Neuralab Ltd |
Composiciones del peptido a-beta y procesos para producir las mismas
|
|
UA81216C2
(en)
|
1999-06-01 |
2007-12-25 |
|
Prevention and treatment of amyloid disease
|
|
AU780474B2
(en)
|
1999-06-16 |
2005-03-24 |
Boston Biomedical Research Institute Incorporated |
Immunological control of beta-amyloid levels in vivo
|
|
DE19927554C2
(de)
*
|
1999-06-16 |
2002-12-19 |
Inst Mikrotechnik Mainz Gmbh |
Mikromischer
|
|
US6596474B1
(en)
|
1999-07-01 |
2003-07-22 |
Scios Inc. |
Prevention and treatment of amyloid-associated disorders
|
|
JP2003522735A
(ja)
|
1999-07-15 |
2003-07-29 |
ジェネティクス インスティチュート，エルエルシー |
Ｉｌ−１１に関する組成物
|
|
HK1047944A1
(zh)
|
1999-08-04 |
2003-03-14 |
The University Of Southern California |
淀粉体乙等蛋白之球形组合及其使用
|
|
JP2003509020A
(ja)
|
1999-09-03 |
2003-03-11 |
ラモット・ユニバーシティ・オーソリティ・フォー・アプライド・リサーチ・アンド・インダストリアル・ディベロップメント・リミテッド |
プラーク形成疾患の診断、治療、予防に有用な薬剤、組成物、その使用法
|
|
US6294171B2
(en)
|
1999-09-14 |
2001-09-25 |
Milkhaus Laboratory, Inc. |
Methods for treating disease states comprising administration of low levels of antibodies
|
|
US6824780B1
(en)
|
1999-10-29 |
2004-11-30 |
Genentech, Inc. |
Anti-tumor antibody compositions and methods of use
|
|
US20020094335A1
(en)
|
1999-11-29 |
2002-07-18 |
Robert Chalifour |
Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases
|
|
WO2001039796A2
(en)
|
1999-11-29 |
2001-06-07 |
Neurochem Inc. |
Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases
|
|
AU784925B2
(en)
|
1999-12-08 |
2006-07-27 |
Intellect Neurosciences, Inc. |
Chimeric peptides (short B-cell epitope joined to a T-cell epitope) and their use for immunization
|
|
US6399314B1
(en)
|
1999-12-29 |
2002-06-04 |
American Cyanamid Company |
Methods of detection of amyloidogenic proteins
|
|
KR20080017471A
(ko)
|
2000-02-21 |
2008-02-26 |
파멕사 에이/에스 |
아밀로이드의 하향-조절을 위한 신규한 방법
|
|
ES2248283T3
(es)
|
2000-02-21 |
2006-03-16 |
Pharmexa A/S |
Nuevo procedimiento para reducir los niveles de amiloide.
|
|
CN104341500A
(zh)
|
2000-02-24 |
2015-02-11 |
华盛顿大学 |
螯合淀粉样蛋白β肽的人源化抗体
|
|
AU2001253158A1
(en)
|
2000-04-05 |
2001-10-23 |
University Of Tennessee Research Corporation |
Methods of investigating, diagnosing, and treating amyloidosis
|
|
EP1385541B1
(en)
|
2000-04-13 |
2008-06-18 |
Corixa Corporation |
Immunostimulant compositions comprising an aminoalkyl glucosaminide phosphate and qs-21
|
|
JP2003534351A
(ja)
|
2000-05-22 |
2003-11-18 |
ニュー・ヨーク・ユニヴァーシティー |
アミロイドβ及びアミロイド沈着物に対する免疫応答誘導のための、アミロイドβと相同的な、合成の、免疫原性だが非アミロイド原性ペプチド
|
|
EP2082749A3
(en)
|
2000-07-07 |
2010-06-30 |
Bioarctic Neuroscience AB |
Prevention and treatment of Alzheimer's disease
|
|
EP1172378A1
(en)
|
2000-07-12 |
2002-01-16 |
Richard Dr. Dodel |
Human beta-amyloid antibody and use thereof for treatment of alzheimer's disease
|
|
US20020009445A1
(en)
|
2000-07-12 |
2002-01-24 |
Yansheng Du |
Human beta-amyloid antibody and use thereof for treatment of alzheimer's disease
|
|
US20030092145A1
(en)
|
2000-08-24 |
2003-05-15 |
Vic Jira |
Viral vaccine composition, process, and methods of use
|
|
AU9063801A
(en)
|
2000-09-06 |
2002-03-22 |
Aventis Pharma Sa |
Methods and compositions for diseases associated with amyloidosis
|
|
IT1319277B1
(it)
|
2000-10-24 |
2003-09-26 |
Chiesi Farma Spa |
Proteine di fusione utili per il trattamento di immunizzazione dellamalattia di alzheimer.
|
|
IL139308A0
(en)
|
2000-10-26 |
2001-11-25 |
Marikovsky Moshe |
Peptides from amyloid precursor protein which inhibit tumor growth and metastasis
|
|
AU2002251682A1
(en)
|
2000-11-02 |
2002-08-28 |
Cornell Research Foundation, Inc. |
In vivo multiphoton diagnostic detection and imaging of a neurodegenerative disease
|
|
DK1346041T3
(da)
|
2000-11-27 |
2007-07-02 |
Praecis Pharm Inc |
Terapeutiske midler og fremgangsmåder til anvendelse deraf til behandling af en amyloidogen sygdom
|
|
PE20020574A1
(es)
|
2000-12-06 |
2002-07-02 |
Wyeth Corp |
Anticuerpos humanizados que reconocen el peptido amiloideo beta
|
|
US7700751B2
(en)
|
2000-12-06 |
2010-04-20 |
Janssen Alzheimer Immunotherapy |
Humanized antibodies that recognize β-amyloid peptide
|
|
WO2002060920A2
(en)
|
2000-12-27 |
2002-08-08 |
Board Of Regents, University Of Texas System |
Prion isomers, methods of making, methods of using, and compositions and products comprising prion isomers
|
|
US20020160394A1
(en)
|
2001-01-24 |
2002-10-31 |
Bayer Corporation |
Regulation of transthyretin to treat obesity
|
|
DE60121729T2
(de)
|
2001-04-19 |
2007-11-29 |
Dr. Hermann Schätzl |
Prion Proteindimere für Impfungen
|
|
ES2437875T3
(es)
|
2001-04-30 |
2014-01-14 |
Eli Lilly And Company |
Anticuerpos humanizados que reconocen el péptido beta-amiloide
|
|
ES2312569T3
(es)
|
2001-04-30 |
2009-03-01 |
Eli Lilly And Company |
Anticuerpos humanizados.
|
|
US6906169B2
(en)
|
2001-05-25 |
2005-06-14 |
United Biomedical, Inc. |
Immunogenic peptide composition comprising measles virus Fprotein Thelper cell epitope (MUFThl-16) and N-terminus of β-amyloid peptide
|
|
GB0113179D0
(en)
|
2001-05-31 |
2001-07-25 |
Novartis Ag |
Organic compounds
|
|
US20020197258A1
(en)
|
2001-06-22 |
2002-12-26 |
Ghanbari Hossein A. |
Compositions and methods for preventing protein aggregation in neurodegenerative diseases
|
|
WO2003009817A2
(en)
|
2001-07-25 |
2003-02-06 |
Protein Design Labs, Inc. |
Stable lyophilized pharmaceutical formulation of igg antibodies
|
|
US20030135035A1
(en)
|
2001-08-09 |
2003-07-17 |
Mark Shannon |
Human ZZAP1 protein
|
|
AU2002324468A1
(en)
|
2001-08-17 |
2003-03-03 |
Eli Lilly And Company |
Rapid improvement of cognition in conditions related to abeta
|
|
CA2451998A1
(en)
|
2001-08-17 |
2003-02-27 |
Eli Lilly And Company |
Anti-a.beta. antibodies
|
|
CA2452104A1
(en)
|
2001-08-17 |
2003-02-27 |
Eli Lilly And Company |
Use of antibodies having high affinity for soluble ass to treat conditions and diseases related to ass
|
|
US20030082191A1
(en)
|
2001-08-29 |
2003-05-01 |
Poduslo Joseph F. |
Treatment for central nervous system disorders
|
|
DE60237459D1
(de)
|
2001-09-10 |
2010-10-07 |
Anticancer Inc |
Verbesserte beobachtungsgenauigkeit bei der absiedelung von tumoren
|
|
US6907297B2
(en)
|
2001-09-28 |
2005-06-14 |
Ethicon, Inc. |
Expandable intracardiac return electrode and method of use
|
|
US7781413B2
(en)
|
2001-10-31 |
2010-08-24 |
Board Of Regents, The University Of Texas System |
SEMA3B inhibits tumor growth and induces apoptosis in cancer cells
|
|
IL161677A0
(en)
|
2001-11-08 |
2004-09-27 |
Protein Design Labs |
Stable liquid pharmaceutical formulation of igg antibodies
|
|
CA2466841A1
(en)
|
2001-11-21 |
2003-06-05 |
New York University |
Synthetic immunogenic but non-deposit-forming polypeptides and peptides homologous to amyloid .beta., prion protein, amylin, .alpha.-synuclein, or polyglutamine repeats for induction of an immune response thereto
|
|
US20050227941A1
(en)
|
2001-12-17 |
2005-10-13 |
Karen Duff |
Sequestration of ass in the periphery in the absence of immunomodulating agent as a therapeutic approach for the treatment or prevention of beta-amyloid related diseases
|
|
AR038568A1
(es)
|
2002-02-20 |
2005-01-19 |
Hoffmann La Roche |
Anticuerpos anti-a beta y su uso
|
|
KR20040094705A
(ko)
|
2002-02-21 |
2004-11-10 |
듀크 유니버시티 |
자가면역질환에 대한 시약 및 치료 방법
|
|
MY139983A
(en)
|
2002-03-12 |
2009-11-30 |
Janssen Alzheimer Immunotherap |
Humanized antibodies that recognize beta amyloid peptide
|
|
US7132100B2
(en)
|
2002-06-14 |
2006-11-07 |
Medimmune, Inc. |
Stabilized liquid anti-RSV antibody formulations
|
|
DE60336902D1
(de)
|
2002-07-19 |
2011-06-09 |
Cytos Biotechnology Ag |
Impfstoffzusammensetzungen enthaltende amyloid beta 1-6 antigenarrays
|
|
JP2006513259A
(ja)
|
2002-07-24 |
2006-04-20 |
イノジェネティックス・ナムローゼ・フェンノートシャップ |
ベータ−アミロイド生成および／または凝集に関連した疾病の防止、処置および診断
|
|
CA2501091A1
(en)
|
2002-10-01 |
2004-04-15 |
Northwestern University |
Amyloid beta-derived diffusible ligands (addls), addl-surrogates, addl-binding molecules, and uses thereof
|
|
FR2846667B1
(fr)
|
2002-11-06 |
2004-12-31 |
Pasteur Institut |
Fragments variables d'anticorps de camelides a chaine unique diriges contre le peptide beta-amyloide 1-42 et leurs applications pour le diagnostic et le traitement des maladies neuroagregatives
|
|
AU2003293543A1
(en)
|
2002-12-13 |
2004-07-09 |
Abgenix, Inc. |
System and method for stabilizing antibodies with histidine
|
|
US6787129B1
(en)
|
2003-01-13 |
2004-09-07 |
Zenitech Llc |
Castor polyester as gloss agents in anionic systems
|
|
RU2390350C2
(ru)
|
2003-02-01 |
2010-05-27 |
Ньюралаб Лимитед |
Активная иммунизация для создания антител к растворимому а-бета
|
|
WO2004071408A2
(en)
|
2003-02-10 |
2004-08-26 |
Applied Molecular Evolution, Inc. |
Aβ BINDING MOLECULES
|
|
PT2335725T
(pt)
|
2003-04-04 |
2017-01-06 |
Novartis Ag |
Formulações de elevada concentração de anticorpos e proteínas
|
|
EP1480041A1
(en)
|
2003-05-22 |
2004-11-24 |
Innogenetics N.V. |
Method for the prediction, diagnosis and differential diagnosis of Alzheimer's disease
|
|
PE20050627A1
(es)
|
2003-05-30 |
2005-08-10 |
Wyeth Corp |
Anticuerpos humanizados que reconocen el peptido beta amiloideo
|
|
US20060182321A1
(en)
|
2003-07-07 |
2006-08-17 |
Agency For Science, Technology And Research |
Method and apparatus for extracting third ventricle information
|
|
WO2005014041A2
(en)
|
2003-07-24 |
2005-02-17 |
Novartis Ag |
Use of an amyloid beta dna vaccine for the treatment and/or prevention of amyloid diseases
|
|
US20060233788A1
(en)
|
2003-09-05 |
2006-10-19 |
Heiman Mark L |
Anti-ghrelin antibodies
|
|
CA2445743A1
(en)
|
2003-10-08 |
2005-04-08 |
The University Of British Columbia |
Methods for modulating neuronal responses
|
|
WO2005035753A1
(ja)
|
2003-10-10 |
2005-04-21 |
Chugai Seiyaku Kabushiki Kaisha |
機能蛋白質を代替する二重特異性抗体
|
|
EA010060B1
(ru)
|
2003-12-17 |
2008-06-30 |
Вайет |
Конъюгаты иммуногенных пептидных носителей и способы их получения
|
|
US8227403B2
(en)
|
2003-12-17 |
2012-07-24 |
Wyeth Llc |
A-β immunogenic peptide carrier conjugates and methods of producing same
|
|
US20050214222A1
(en)
|
2004-02-13 |
2005-09-29 |
Mckinnon Stuart J |
In vivo imaging of amyloid plaques in glaucoma using intravenous injectable dyes
|
|
ES2367576T3
(es)
|
2004-03-15 |
2011-11-04 |
Janssen Pharmaceutica Nv |
Nuevos compuestos como moduladores de receptores opioides.
|
|
CN102973954A
(zh)
|
2004-07-02 |
2013-03-20 |
匹兹堡大学高等教育联邦体系 |
淀粉样蛋白成像作为抗淀粉样蛋白疗法的功效的替代标记物
|
|
EP2298807A3
(en)
|
2004-07-30 |
2011-05-18 |
Rinat Neuroscience Corp. |
Antibodies directed against amyloid-beta peptide and methods using same
|
|
GT200500255A
(es)
|
2004-09-10 |
2006-04-10 |
|
Anticuerpos anti-5ta humanizados y conjugados anticuerpo anti-5ta/calicheamicina
|
|
MX2007003906A
(es)
|
2004-10-05 |
2007-05-21 |
Wyeth Corp |
Metodos y composiciones para mejorar la produccion de proteinas recombinantes.
|
|
US20060160161A1
(en)
|
2004-10-26 |
2006-07-20 |
Elan Pharmaceuticals, Inc. |
Methods for assessing antibodies to neurodegenerative disease-associated antigens
|
|
US20060240486A1
(en)
|
2004-12-15 |
2006-10-26 |
Johnson-Wood Kelly L |
Immunoprecipitation-based assay for predicting in vivo efficacy of beta-amyloid antibodies
|
|
TW200636066A
(en)
|
2004-12-15 |
2006-10-16 |
Elan Pharm Inc |
Humanized antibodies that recognize beta amyloid peptide
|
|
JP2008523815A
(ja)
|
2004-12-15 |
2008-07-10 |
エラン ファーマ インターナショナル リミテッド |
認知の改善における使用のためのヒト化アミロイドβ抗体
|
|
WO2006066118A2
(en)
|
2004-12-15 |
2006-06-22 |
Neuralab Limited |
Contextual fear test for predicting efficacy of alzheimer immunotherapeutic treatment
|
|
AR051800A1
(es)
|
2004-12-15 |
2007-02-07 |
Wyeth Corp |
Anticuerpos a beta usados en mejorar la cognicion
|
|
DOP2006000022A
(es)
|
2005-01-28 |
2006-08-15 |
Wyeth Corp |
Formulaciones líquidas estabilizadas de polipetidos
|
|
GT200600031A
(es)
|
2005-01-28 |
2006-08-29 |
|
Formulacion anticuerpo anti a beta
|
|
AU2006246382A1
(en)
|
2005-05-05 |
2006-11-16 |
Merck Sharp & Dohme Corp. |
Peptide conjugate compositions and methods for the prevention and treatment of Alzheimer's disease
|
|
EA015148B1
(ru)
|
2005-06-17 |
2011-06-30 |
Элан Фарма Интернэшнл Лимитед |
СПОСОБЫ ОЧИСТКИ Aβ-СВЯЗЫВАЮЩЕГО БЕЛКА, СОДЕРЖАЩЕГО ОБЛАСТЬ FC
|
|
ATE550338T1
(de)
|
2005-07-18 |
2012-04-15 |
Merck Sharp & Dohme |
Spiropiperidininhibitoren von beta-secretase zur behandlung von alzheimer-krankheit
|
|
EP3211946B1
(en)
|
2005-10-04 |
2018-09-19 |
Huawei Technologies Co., Ltd. |
A method and system for determining the group number used by mobile terminals having a same frequency band position for receiving signals in idle mode
|
|
EP1951750A4
(en)
|
2005-11-10 |
2009-12-09 |
Roskamp Res Llc |
MODULATION OF THE ANGIOGENESIS BY A-BETA PEPTIDE FRAGMENTS
|
|
US8227576B2
(en)
|
2006-03-30 |
2012-07-24 |
Glaxo Group Limited |
Antibodies against amyloid-β peptide
|
|
US8784810B2
(en)
|
2006-04-18 |
2014-07-22 |
Janssen Alzheimer Immunotherapy |
Treatment of amyloidogenic diseases
|
|
WO2010044803A1
(en)
|
2008-10-17 |
2010-04-22 |
Elan Pharma International Limited |
Treatment of amyloidogenic diseases
|
|
EP2046833B9
(en)
|
2006-07-14 |
2014-02-19 |
AC Immune S.A. |
Humanized antibody against amyloid beta
|
|
EP2120717A1
(en)
|
2007-03-12 |
2009-11-25 |
National Institute of Radiological Sciences |
Pet visualization of amyloid-associated neuroinflammation in the brain
|
|
US20080292625A1
(en)
|
2007-04-18 |
2008-11-27 |
Sally Schroeter |
Prevention and treatment of cerebral amyloid angiopathy
|
|
US8003097B2
(en)
|
2007-04-18 |
2011-08-23 |
Janssen Alzheimer Immunotherapy |
Treatment of cerebral amyloid angiopathy
|
|
SI2182983T1
(sl)
|
2007-07-27 |
2014-09-30 |
Janssen Alzheimer Immunotherapy |
Zdravljenje amiloidogenih bolezni s humaniziranimi protitelesi proti abeta
|
|
WO2011133919A1
(en)
|
2010-04-22 |
2011-10-27 |
Janssen Alzheimer Immunotherapy |
Use of tau to monitor immunotherapy
|
|
JO3076B1
(ar)
|
2007-10-17 |
2017-03-15 |
Janssen Alzheimer Immunotherap |
نظم العلاج المناعي المعتمد على حالة apoe
|
|
WO2009086539A2
(en)
|
2007-12-28 |
2009-07-09 |
Elan Pharmaceuticals, Inc. |
Treatment and prophylaxis of amyloidosis
|
|
KR20160135843A
(ko)
|
2008-09-18 |
2016-11-28 |
세다르스-신나이 메디칼 센터 |
알츠하이머병의 검출을 위한 광학적 방법
|
|
WO2011106732A1
(en)
|
2010-02-25 |
2011-09-01 |
Wyeth Llc |
Pet monitoring of ab-directed immunotherapy
|