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UY28131A1 - BICYCLE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELLULAR GROWTH - Google Patents

BICYCLE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELLULAR GROWTH

Info

Publication number
UY28131A1
UY28131A1 UY28131A UY28131A UY28131A1 UY 28131 A1 UY28131 A1 UY 28131A1 UY 28131 A UY28131 A UY 28131A UY 28131 A UY28131 A UY 28131A UY 28131 A1 UY28131 A1 UY 28131A1
Authority
UY
Uruguay
Prior art keywords
formula
compounds
treatment
cellular growth
abnormal cellular
Prior art date
Application number
UY28131A
Other languages
Spanish (es)
Inventor
John Charles Kath
Zhengyu Liu
Maria Steflik Brown
Steven Mark Winter
Susan Jane Truesdell
Ruby Anthea Szewc
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Priority to UY28131A priority Critical patent/UY28131A1/en
Publication of UY28131A1 publication Critical patent/UY28131A1/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La invención se refiere a compuestos de fórmula 1 y a sales, pro fármacos y solvatos farmacéuticamente aceptables de los mismos, en la que R1, R2, R3 y R5 son como se definen en la presente memoria, y en la que el compuesto de fórmula 1 comprende opcionalmente además un sustituyente hidroxi o un ácido O-glucurónico. La invención se refiere también a procedimientos de tratamiento del crecimiento celular anormal en mamíferos mediante la administración de los compuesto de fórmula 1 y a composiciones farmacéuticas para tratar dichos trastornos que contienen los compuestos de fórmula 1. La invención se refiere también a procedimientos de preparación de los compuestos de fórmula 1.The invention relates to compounds of formula 1 and pharmaceutically acceptable salts, pro drugs and solvates thereof, wherein R1, R2, R3 and R5 are as defined herein, and in which the compound of formula 1 optionally further comprises a hydroxy substituent or an O-glucuronic acid. The invention also relates to methods of treating abnormal cell growth in mammals by administering the compounds of formula 1 and pharmaceutical compositions for treating such disorders containing the compounds of formula 1. The invention also relates to methods of preparing the compounds of formula 1.

UY28131A 2003-12-17 2003-12-17 BICYCLE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELLULAR GROWTH UY28131A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
UY28131A UY28131A1 (en) 2003-12-17 2003-12-17 BICYCLE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELLULAR GROWTH

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
UY28131A UY28131A1 (en) 2003-12-17 2003-12-17 BICYCLE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELLULAR GROWTH

Publications (1)

Publication Number Publication Date
UY28131A1 true UY28131A1 (en) 2004-07-30

Family

ID=38812860

Family Applications (1)

Application Number Title Priority Date Filing Date
UY28131A UY28131A1 (en) 2003-12-17 2003-12-17 BICYCLE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELLULAR GROWTH

Country Status (1)

Country Link
UY (1) UY28131A1 (en)

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20160120