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UY27241A1 - INDOLINONES REPLACED IN POSITIONS 6, ITS PREPARATION AND USE AS MEDICATIONS - Google Patents

INDOLINONES REPLACED IN POSITIONS 6, ITS PREPARATION AND USE AS MEDICATIONS

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Publication number
UY27241A1
UY27241A1 UY27241A UY27241A UY27241A1 UY 27241 A1 UY27241 A1 UY 27241A1 UY 27241 A UY27241 A UY 27241A UY 27241 A UY27241 A UY 27241A UY 27241 A1 UY27241 A1 UY 27241A1
Authority
UY
Uruguay
Prior art keywords
preparation
indolinones
medications
replaced
positions
Prior art date
Application number
UY27241A
Other languages
Spanish (es)
Inventor
Dr Jacobus Van Meel
Dr Frank Hilberg
Dr Thorsten Lehmann-Lintz
Dr Gerald Jurgen Roth
Dr Armin Heckel
Dr Jnrg Kley
Original Assignee
Boehringer Ingelheim Pharma
Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma, Co Kg filed Critical Boehringer Ingelheim Pharma
Priority to UY27241A priority Critical patent/UY27241A1/en
Publication of UY27241A1 publication Critical patent/UY27241A1/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

El presente invento se refiere a indolinonas sustituidas en posición 6 de la fórmula general (I) en la que R1 hasta R5 y X están definidos como en la reivindicación 1, sus isómeros y sus sales, en particular sus sales fisiológicamente compatibles, que presentan valiosas propiedades farmacológicas, en particular un efecto inhibidor sobre diferentes tirosina-cinasas de receptores y complejos de ciclinas y CDK, así como sobre la proliferación de células endoteliales diferentes células tumorales, medicamentos que contienen estos compuestos, su utilización y procedimientos para su preparación.The present invention relates to indolinones substituted in position 6 of the general formula (I) in which R1 to R5 and X are defined as in claim 1, their isomers and their salts, in particular their physiologically compatible salts, which have valuable Pharmacological properties, in particular an inhibitory effect on different receptor tyrosine kinases and cyclin and CDK complexes, as well as on the proliferation of different tumor cell endothelial cells, medications containing these compounds, their use and procedures for their preparation.

UY27241A 2002-04-04 2002-04-04 INDOLINONES REPLACED IN POSITIONS 6, ITS PREPARATION AND USE AS MEDICATIONS UY27241A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
UY27241A UY27241A1 (en) 2002-04-04 2002-04-04 INDOLINONES REPLACED IN POSITIONS 6, ITS PREPARATION AND USE AS MEDICATIONS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
UY27241A UY27241A1 (en) 2002-04-04 2002-04-04 INDOLINONES REPLACED IN POSITIONS 6, ITS PREPARATION AND USE AS MEDICATIONS

Publications (1)

Publication Number Publication Date
UY27241A1 true UY27241A1 (en) 2002-12-31

Family

ID=38812616

Family Applications (1)

Application Number Title Priority Date Filing Date
UY27241A UY27241A1 (en) 2002-04-04 2002-04-04 INDOLINONES REPLACED IN POSITIONS 6, ITS PREPARATION AND USE AS MEDICATIONS

Country Status (1)

Country Link
UY (1) UY27241A1 (en)

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20141119