[go: up one dir, main page]

UY26574A1 - " procedimiento para la separación enzimática de racematos de derivados de aminometil-aril-ciclohexanol". - Google Patents

" procedimiento para la separación enzimática de racematos de derivados de aminometil-aril-ciclohexanol".

Info

Publication number
UY26574A1
UY26574A1 UY26574A UY26574A UY26574A1 UY 26574 A1 UY26574 A1 UY 26574A1 UY 26574 A UY26574 A UY 26574A UY 26574 A UY26574 A UY 26574A UY 26574 A1 UY26574 A1 UY 26574A1
Authority
UY
Uruguay
Prior art keywords
racemates
aryl
procedure
aminometil
enzymatic separation
Prior art date
Application number
UY26574A
Other languages
English (en)
Inventor
Helmut Buschmann
Dagmar Kaulartz
Carsten Griebel
Hans-Joachim Gais
Original Assignee
Gruenenthal Chemie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7629816&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY26574(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gruenenthal Chemie filed Critical Gruenenthal Chemie
Publication of UY26574A1 publication Critical patent/UY26574A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/001—Amines; Imines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Un procedimiento para la separación enzimática de racematos de derivados de aminometil-aril-ciclohexanol.
UY26574A 2000-02-04 2001-02-02 " procedimiento para la separación enzimática de racematos de derivados de aminometil-aril-ciclohexanol". UY26574A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10004926A DE10004926A1 (de) 2000-02-04 2000-02-04 Verfahren zur enzymatischen Racematspaltung von Aminomethyl-Aryl-Cyclohexanol-Derivaten

Publications (1)

Publication Number Publication Date
UY26574A1 true UY26574A1 (es) 2001-04-30

Family

ID=7629816

Family Applications (1)

Application Number Title Priority Date Filing Date
UY26574A UY26574A1 (es) 2000-02-04 2001-02-02 " procedimiento para la separación enzimática de racematos de derivados de aminometil-aril-ciclohexanol".

Country Status (20)

Country Link
US (1) US7168937B2 (es)
EP (1) EP1252327B1 (es)
JP (1) JP2003528049A (es)
AR (1) AR027327A1 (es)
AT (1) ATE274599T1 (es)
AU (2) AU2001230192B2 (es)
CA (1) CA2399819C (es)
CO (1) CO5271656A1 (es)
DE (2) DE10004926A1 (es)
DK (1) DK1252327T3 (es)
ES (1) ES2227118T3 (es)
HU (1) HUP0204430A3 (es)
MX (1) MXPA02007594A (es)
NZ (1) NZ521087A (es)
PE (1) PE20011075A1 (es)
PT (1) PT1252327E (es)
SI (1) SI1252327T1 (es)
TR (1) TR200402470T4 (es)
UY (1) UY26574A1 (es)
WO (1) WO2001057232A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10049481A1 (de) * 2000-09-29 2002-05-02 Gruenenthal Gmbh Substituierte C-Cyclohexylmethylamin-Derivate
DE10059413A1 (de) * 2000-11-30 2002-06-20 Gruenenthal Gmbh Verwendung von substituierten 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbindungen zur Therapie der Harninkontinenz
DE10059411A1 (de) * 2000-11-30 2002-06-13 Gruenenthal Gmbh Verwendung von 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbindungen zur Therapie der Harninkontinenz
PT1562567T (pt) 2002-11-22 2017-08-24 Gruenenthal Gmbh Combinação de analgésicos selecionados e inibidores da cox-ii
US7094795B2 (en) 2003-02-27 2006-08-22 Sanofi-Aventis Deutschland Gmbh Process for preparing the enantiomeric forms of cis-configured 1,3-cyclohexanediol derivatives
DE10308350B4 (de) * 2003-02-27 2006-06-01 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung der enantiomeren Formen von cis-konfigurierten 1,3-Cyclohexandiol-Derivaten
DE102004038403B4 (de) * 2004-08-07 2006-08-31 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung der enantiomeren Formen von cis-konfigurierten 3-Hydroxycyclohexancarbonsäure-Derivaten
US20060211887A1 (en) * 2005-02-25 2006-09-21 Gruenenthal Gmbh Phosphate salts of 6-dimethylaminomethyl-1-(3-methoxyphenyl)-1,3-dihydroxy-cyclohexane compounds
DE102007022790A1 (de) * 2007-05-11 2008-11-20 Grünenthal GmbH Axomadol zur Schmerzbehandlung bei Arthrose

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN162851B (es) * 1980-09-19 1988-07-16 Pfizer
JP3049403B2 (ja) 1991-11-01 2000-06-05 チッソ株式会社 光学活性トランス−２−アリール−１−シクロヘキサノール誘導体およびその製造法
CA2068038A1 (en) * 1991-05-08 1992-11-09 Christopher Yee Enzymatic resolution of .alpha.-tertiary carboxylic acid esters
ES2230790T3 (es) * 1992-01-15 2005-05-01 E.R. SQUIBB & SONS, INC. Procedimientos enzimaticos para la resolucion de mezclas enantiomericas de compuestos utiles como intermedios en la preparacion de taxanos.
DE4217506A1 (de) 1992-05-27 1993-12-02 Boehringer Mannheim Gmbh Mikrobielle Esterase zur enantioselektiven Spaltung von 1-Arylalkylestern
ES2046950B1 (es) 1992-06-08 1994-10-01 Menarini Lab Proceso para la produccion de acido s-(+)-2-(3-benzoilfenil)propionico por hidrolisis enantioselectiva catalizada enzimaticamente.
JPH07101921A (ja) 1993-10-01 1995-04-18 Chisso Corp 光学活性トリフルオロメチルベンジルアルコール誘導体およびその製造法
DE4414273A1 (de) 1994-04-23 1995-10-26 Chemie Linz Deutschland Enzymatische Racematspaltung asymmetrischer Alkohole mittels Vinylestern mehrbasiger Carbonsäuren
US5696299A (en) 1994-10-26 1997-12-09 The Nisshin Oil Mills, Ltd. Optical resolution for producing optically active alcohol
US5770438A (en) * 1994-11-01 1998-06-23 Takeda Chemical Industries, Ltd. Process for enantioselective hydrolysis of α-(2-amino)-phenyl-benzenemethanol ester type compounds using bacillus, pseudomonas or streptomyces
JPH08322590A (ja) 1995-06-05 1996-12-10 Chisso Corp 光学活性２ー（１−ナフチル）シクロヘキサン−１−オール誘導体及びその製造方法
DE19525137C2 (de) * 1995-07-11 2003-02-27 Gruenenthal Gmbh 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbin -dungen als Zwischenprodukte zur Herstellung pharmazeutischer Wirkstoffe
JPH09121564A (ja) 1995-10-27 1997-05-06 Kasei Optonix Co Ltd 静電アクチュエータ
DE19547766A1 (de) 1995-12-20 1997-06-26 Gruenenthal Gmbh 1-Phenyl-2-dimethylaminomethyl-cyclohexan-1-ol-verbindungen als pharmazeutische Wirkstoffe
ATE275394T1 (de) 1997-03-11 2004-09-15 Arakis Ltd R- und s- enantiomere getrennteteile enthaltende dosierungsformen

Also Published As

Publication number Publication date
US7168937B2 (en) 2007-01-30
MXPA02007594A (es) 2002-12-13
PT1252327E (pt) 2004-12-31
TR200402470T4 (tr) 2004-12-21
ES2227118T3 (es) 2005-04-01
HUP0204430A3 (en) 2005-05-30
NZ521087A (en) 2005-11-25
ATE274599T1 (de) 2004-09-15
DE50103394D1 (de) 2004-09-30
AU3019201A (en) 2001-08-14
DK1252327T3 (da) 2004-11-01
HK1051558A1 (en) 2003-08-08
HUP0204430A2 (en) 2003-05-28
CA2399819A1 (en) 2001-08-09
WO2001057232B1 (de) 2002-01-10
AR027327A1 (es) 2003-03-26
SI1252327T1 (en) 2004-12-31
EP1252327B1 (de) 2004-08-25
CA2399819C (en) 2011-04-12
JP2003528049A (ja) 2003-09-24
EP1252327A1 (de) 2002-10-30
CO5271656A1 (es) 2003-04-30
AU2001230192B2 (en) 2006-07-13
WO2001057232A1 (de) 2001-08-09
PE20011075A1 (es) 2001-12-29
DE10004926A1 (de) 2001-08-09
US20030186396A1 (en) 2003-10-02

Similar Documents

Publication Publication Date Title
BR9906888A (pt) "travessa"
ES2180899T3 (es) Dihidrato d de olanzapina.
EA200000381A1 (ru) Препарат 2-метил-тиено-бензодиазепина
EA199900373A2 (ru) Фармацевтические композиции
MXPA02009706A (es) Metodo para sintesis de perindopril y sus sales farmaceuticamente aceptables.
BRPI0112375B8 (pt) aplidinas como derivados antitumorais
GB0031527D0 (en) New use
DK0700380T3 (da) N-Alkylthiopolyaminderivater som radioprotektive midler
IT1307928B1 (it) Metodo di sintesi di nitrossimetilfenil esteri di derivatidell'aspirina.
BR0114903A (pt) 7-azaindóis, sua aplicação como inibidores da fosfodiesterase 4 e processos para a sua preparação
DK1468689T3 (da) 2-methyl-thieno-benzodiazepine formulation
SV1999000060A (es) Procedimiento para la preparacion de (s,s)-bencil-2,8-diazabiciclo 4.3.0 nonano ref. 32965-sv
BR9813905A (pt) Instalação para influenciar uma instalação de iluminação
UY26574A1 (es) " procedimiento para la separación enzimática de racematos de derivados de aminometil-aril-ciclohexanol".
ES2177877T3 (es) Procedimiento para la fabricacion de 1,4-bis(aminometil)ciclohexano.
IS2273B (is) Aðferð fyrir nýsmíðina á HIV próteasa lötum
PT915988E (pt) Processo para a producao fermentativa de cefalosporinas desaciladas
ES2174150T3 (es) Procedimiento para la obtencion de 4-hidroxianilinas.
AR027349A1 (es) Derivados de amidas heterociclicas
AR027751A1 (es) Proceso para la n-formilacion selectiva de n-hidroxilaminas
EP1351680B8 (fr) Utilisation de l'anethole-dithiolethione dans la prevention et le traitement de la tenotoxicite induite par un medicament
ES2188222T3 (es) Sintesis enantioselectiva.
GT199900057A (es) Procedimiento para la preparaciòn de ( s , s ) - bencil - 2,8 - diazabiciclo 4.3.0. nonano.
TR199801514A3 (tr) N-Piruvil-L-Prolin üretimi için yöntem.
ECSP972052A (es) Quinoxalinadionas

Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20121115