UY26547A1 - AMIDE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR INHIBITING PROTEINKINASES, AND THEIR METHOD OF USE - Google Patents
AMIDE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR INHIBITING PROTEINKINASES, AND THEIR METHOD OF USEInfo
- Publication number
- UY26547A1 UY26547A1 UY26547A UY26547A UY26547A1 UY 26547 A1 UY26547 A1 UY 26547A1 UY 26547 A UY26547 A UY 26547A UY 26547 A UY26547 A UY 26547A UY 26547 A1 UY26547 A1 UY 26547A1
- Authority
- UY
- Uruguay
- Prior art keywords
- pharmaceutical compositions
- compounds
- amide compounds
- proteinkinases
- inhibiting
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- -1 AMIDE COMPOUNDS Chemical class 0.000 title abstract 2
- 102000001253 Protein Kinase Human genes 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 108060006633 protein kinase Proteins 0.000 title abstract 2
- 230000002401 inhibitory effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 230000004663 cell proliferation Effects 0.000 abstract 2
- 206010012689 Diabetic retinopathy Diseases 0.000 abstract 1
- 208000010412 Glaucoma Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 206010029113 Neovascularisation Diseases 0.000 abstract 1
- 102000004022 Protein-Tyrosine Kinases Human genes 0.000 abstract 1
- 108090000412 Protein-Tyrosine Kinases Proteins 0.000 abstract 1
- 201000004681 Psoriasis Diseases 0.000 abstract 1
- 230000033115 angiogenesis Effects 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 230000026683 transduction Effects 0.000 abstract 1
- 238000010361 transduction Methods 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Se describen los compuestos de las amidas que modulan y/o inhiben la actividad de ciertas proteínas cinasa. Estos compuestos y las composiciones farmacéuticas que los contienen son capaces de actuar como mediador de la senal de transducción de la tirosina cinasa con el fin de modular y/o inhibir la proliferación celular indeseada. La invención también va dirigida al uso terapéutico o profiláctico de las composiciones farmacéuticas que contienen dichos compuetos, y a los métodos para el tratamiento del cáncer y de otras enfermedades asociadas a la angiogénesis y/o proliferación celular indeseada, tal como lo son la retinopatía diabética, neovascularización del glaucoma, artritis reumatoide, y soriasis, mediante la administración de cantidades eficaces de dichos compuestos.The amide compounds that modulate and / or inhibit the activity of certain protein kinases are described. These compounds and the pharmaceutical compositions containing them are capable of acting as a mediator of the tyrosine kinase transduction signal in order to modulate and / or inhibit unwanted cell proliferation. The invention is also directed to the therapeutic or prophylactic use of pharmaceutical compositions containing said compounds, and to methods for the treatment of cancer and other diseases associated with angiogenesis and / or unwanted cell proliferation, such as diabetic retinopathy, neovascularization of glaucoma, rheumatoid arthritis, and psoriasis, by administering effective amounts of these compounds.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| UY26547A UY26547A1 (en) | 2001-01-19 | 2001-01-19 | AMIDE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR INHIBITING PROTEINKINASES, AND THEIR METHOD OF USE |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| UY26547A UY26547A1 (en) | 2001-01-19 | 2001-01-19 | AMIDE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR INHIBITING PROTEINKINASES, AND THEIR METHOD OF USE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UY26547A1 true UY26547A1 (en) | 2001-09-28 |
Family
ID=38812320
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UY26547A UY26547A1 (en) | 2001-01-19 | 2001-01-19 | AMIDE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR INHIBITING PROTEINKINASES, AND THEIR METHOD OF USE |
Country Status (1)
| Country | Link |
|---|---|
| UY (1) | UY26547A1 (en) |
-
2001
- 2001-01-19 UY UY26547A patent/UY26547A1/en not_active Application Discontinuation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 109 | Application deemed to be withdrawn |
Effective date: 20120814 |