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UY25348A1 - Procedimiento para preparar una cetoimina - Google Patents

Procedimiento para preparar una cetoimina

Info

Publication number
UY25348A1
UY25348A1 UY25348A UY25348A UY25348A1 UY 25348 A1 UY25348 A1 UY 25348A1 UY 25348 A UY25348 A UY 25348A UY 25348 A UY25348 A UY 25348A UY 25348 A1 UY25348 A1 UY 25348A1
Authority
UY
Uruguay
Prior art keywords
formula
monomethylamine
dichlorophenyl
dihydro
cetoimin
Prior art date
Application number
UY25348A
Other languages
English (en)
Inventor
Carlos Colberg Juan
Michael Pfisterer David
Patricia Taber Geraldine
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22102365&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY25348(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of UY25348A1 publication Critical patent/UY25348A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/02—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

Esta invención se refiere a un procedimiento para preparar N-[4,(3,4-diclorofenil)-3,4-dihidro-1(2H)-naftaleniliden]metanamina de fórmula l que comprende hacer reaccionar 4-(3,4-diclorofenil)-3,4-dihidro-1(2H)-naftalenona de fórmula ll y monometilamina en un alcohol como disolvente, seleccionado de alcanoles primarios, secundarios y terciarios, lineales o ramificados, y otro alcoholes que tengan un punto de ebullición en las condiciones de reacción, mayor que 55ºC y en los que sea soluble la monometilamina. Un procedimiento en el que la cetoimina producto de fórmula ll se hidrogena in situ en el mismo alcohol en el que se ha formado, proporcionando una mezcla de cis sertralina racémica y trans sertralina racémica.
UY25348A 1998-01-16 1999-01-13 Procedimiento para preparar una cetoimina UY25348A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7160098P 1998-01-16 1998-01-16

Publications (1)

Publication Number Publication Date
UY25348A1 true UY25348A1 (es) 1999-09-27

Family

ID=22102365

Family Applications (1)

Application Number Title Priority Date Filing Date
UY25348A UY25348A1 (es) 1998-01-16 1999-01-13 Procedimiento para preparar una cetoimina

Country Status (47)

Country Link
US (1) US6232500B1 (es)
EP (1) EP1047666B1 (es)
JP (1) JP3533179B2 (es)
KR (1) KR100362788B1 (es)
CN (1) CN1121381C (es)
AP (1) AP956A (es)
AR (1) AR016168A1 (es)
AT (1) ATE231121T1 (es)
AU (1) AU747861B2 (es)
BG (2) BG64621B1 (es)
BR (1) BR9814248A (es)
CA (1) CA2315761C (es)
CO (1) CO5040154A1 (es)
CZ (1) CZ20002594A3 (es)
DE (1) DE69810815T2 (es)
DK (1) DK1047666T3 (es)
DZ (1) DZ2705A1 (es)
EA (1) EA004952B1 (es)
EG (1) EG21515A (es)
ES (1) ES2186226T3 (es)
GT (1) GT199800176A (es)
HN (1) HN1998000167A (es)
HR (1) HRP20000473A2 (es)
HU (1) HUP0101253A3 (es)
ID (1) ID24971A (es)
IL (2) IL136888A0 (es)
IN (1) IN191358B (es)
IS (1) IS5538A (es)
MA (1) MA24744A1 (es)
MY (1) MY132956A (es)
NO (1) NO20003625L (es)
NZ (1) NZ505027A (es)
OA (1) OA11439A (es)
PA (1) PA8461901A1 (es)
PE (1) PE20000171A1 (es)
PL (1) PL192489B1 (es)
PT (1) PT1047666E (es)
RS (1) RS49773B (es)
SI (1) SI1047666T1 (es)
SK (1) SK10182000A3 (es)
TN (1) TNSN99004A1 (es)
TR (1) TR200002065T2 (es)
TW (1) TW505624B (es)
UA (1) UA55504C2 (es)
UY (1) UY25348A1 (es)
WO (1) WO1999036394A1 (es)
ZA (1) ZA99278B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU226423B1 (en) * 1998-05-05 2008-12-29 Egis Gyogyszergyar Nyrt Process for producing a 1(2h)-naphtalene-1-ylidene derivative
WO2000026181A1 (de) * 1998-10-30 2000-05-11 Ciba Specialty Chemicals Holding Inc. Verfahren zur herstellung von ketiminen
EP1630156A1 (en) * 1998-11-27 2006-03-01 Teva Pharmaceutical Industries Ltd Sertraline hydrochloride polymorphs
IN185109B (es) * 1999-09-01 2000-11-18 Torrent Pharmaceuticals Ltd
ATE299862T1 (de) * 1999-11-16 2005-08-15 Ciba Sc Holding Ag Verfahren zur herstellung von ketiminen
DE60020153T2 (de) 1999-11-16 2006-01-26 Ciba Speciality Chemicals Holding Inc. Verfahren zur herstellung von ketiminen
IN187170B (es) 2000-01-04 2002-02-23 Sun Pharmaceutical Ind Ltd
KR20070002102A (ko) * 2000-03-14 2007-01-04 테바 파마슈티컬 인더스트리즈 리미티드 (+)-시스-세르트랄린의 신규한 제조 방법
EP1397342A1 (en) * 2001-05-31 2004-03-17 Orion Corporation Fermion Process for preparing sertraline intermediates
US6723878B2 (en) 2001-06-15 2004-04-20 Orion Corporation Fermion Method for preparing sertraline
KR20030061474A (ko) * 2002-01-14 2003-07-22 한미약품 주식회사 서트랄린 제조용 중간체로서 사용되는 시스-라세메이트화합물의 개선된 제조방법
EP1885683A2 (en) 2005-06-03 2008-02-13 Hetero Drugs Limited A highly stereoselective synthesis of sertraline

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4536518A (en) 1979-11-01 1985-08-20 Pfizer Inc. Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine
US4855500A (en) * 1988-05-04 1989-08-08 Pfizer Inc. Process for preparing a ketimine
HU226424B1 (en) 1998-05-05 2008-12-29 Egis Gyogyszergyar Nyrt Process for producing enantiomer mixture for preparation of sertraline

Also Published As

Publication number Publication date
PL192489B1 (pl) 2006-10-31
PL341648A1 (en) 2001-04-23
BG104669A (en) 2001-04-30
WO1999036394A1 (en) 1999-07-22
HRP20000473A2 (en) 2001-04-30
US6232500B1 (en) 2001-05-15
TW505624B (en) 2002-10-11
IS5538A (is) 2000-06-16
PA8461901A1 (es) 2000-05-24
KR20010034117A (ko) 2001-04-25
OA11439A (en) 2004-04-26
NO20003625D0 (no) 2000-07-14
EA200000661A1 (ru) 2000-12-25
IL136888A (en) 2006-12-10
EP1047666A1 (en) 2000-11-02
ID24971A (id) 2000-08-31
CN1285819A (zh) 2001-02-28
MY132956A (en) 2007-10-31
ATE231121T1 (de) 2003-02-15
RS49773B (sr) 2008-06-05
EP1047666B1 (en) 2003-01-15
PT1047666E (pt) 2003-03-31
BG64647B1 (bg) 2005-10-31
MA24744A1 (fr) 1999-10-01
PE20000171A1 (es) 2000-03-09
BR9814248A (pt) 2000-10-10
NZ505027A (en) 2002-08-28
AU9278698A (en) 1999-08-02
GT199800176A (es) 1998-11-09
JP2002509132A (ja) 2002-03-26
SI1047666T1 (en) 2003-04-30
IN191358B (es) 2003-11-29
ES2186226T3 (es) 2003-05-01
DE69810815T2 (de) 2003-08-07
YU44300A (sh) 2002-09-19
CA2315761A1 (en) 1999-07-22
DZ2705A1 (fr) 2003-09-01
CN1121381C (zh) 2003-09-17
HUP0101253A3 (en) 2002-06-28
CZ20002594A3 (cs) 2001-12-12
HK1032039A1 (en) 2001-07-06
CA2315761C (en) 2004-08-31
AU747861B2 (en) 2002-05-23
HN1998000167A (es) 1999-02-09
AR016168A1 (es) 2001-06-20
SK10182000A3 (sk) 2002-06-04
UA55504C2 (uk) 2003-04-15
EA004952B1 (ru) 2004-10-28
JP3533179B2 (ja) 2004-05-31
KR100362788B1 (ko) 2002-11-29
AP9901441A0 (en) 1999-03-31
EG21515A (en) 2001-11-28
TNSN99004A1 (fr) 2005-11-10
BG64621B1 (bg) 2005-09-30
DE69810815D1 (de) 2003-02-20
CO5040154A1 (es) 2001-05-29
ZA99278B (en) 2000-07-17
TR200002065T2 (tr) 2000-11-21
NO20003625L (no) 2000-09-13
HUP0101253A2 (hu) 2002-05-29
IL136888A0 (en) 2001-06-14
AP956A (en) 2001-04-06
DK1047666T3 (da) 2003-02-24

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Legal Events

Date Code Title Description
VENC Patent expired

Effective date: 20190113