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UY25677A1 - NEW BACTERIAL AGENTS OF ISOXAZOLINONE - Google Patents

NEW BACTERIAL AGENTS OF ISOXAZOLINONE

Info

Publication number
UY25677A1
UY25677A1 UY25677A UY25677A UY25677A1 UY 25677 A1 UY25677 A1 UY 25677A1 UY 25677 A UY25677 A UY 25677A UY 25677 A UY25677 A UY 25677A UY 25677 A1 UY25677 A1 UY 25677A1
Authority
UY
Uruguay
Prior art keywords
isoxazolinone
bacterial agents
new bacterial
new
isoxazolinones
Prior art date
Application number
UY25677A
Other languages
Spanish (es)
Inventor
Lawrence B Snyder Y Zhiz Zheng
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of UY25677A1 publication Critical patent/UY25677A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/12—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Esta invención describe derivados de isoxazolina que poseen actividad antibacteriana y son útiles en el tratamiento de enfermedades bacterianas. En forma más particular, se proporcionan nuevas isoxazolinonas (fórmula general ver en solicitud).This invention describes isoxazoline derivatives that possess antibacterial activity and are useful in the treatment of bacterial diseases. More particularly, new isoxazolinones are provided (general formula see on request).

UY25677A 1998-08-24 1999-08-24 NEW BACTERIAL AGENTS OF ISOXAZOLINONE UY25677A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9757498P 1998-08-24 1998-08-24

Publications (1)

Publication Number Publication Date
UY25677A1 true UY25677A1 (en) 2001-08-27

Family

ID=22264103

Family Applications (1)

Application Number Title Priority Date Filing Date
UY25677A UY25677A1 (en) 1998-08-24 1999-08-24 NEW BACTERIAL AGENTS OF ISOXAZOLINONE

Country Status (22)

Country Link
EP (1) EP1107756A4 (en)
JP (1) JP2002523369A (en)
KR (1) KR20010072945A (en)
CN (1) CN1314813A (en)
AR (1) AR020250A1 (en)
AU (1) AU748750B2 (en)
BR (1) BR9913225A (en)
CA (1) CA2341271A1 (en)
CO (1) CO5160266A1 (en)
CZ (1) CZ2001669A3 (en)
HU (1) HUP0103433A3 (en)
ID (1) ID27690A (en)
IL (1) IL141542A0 (en)
NO (1) NO20010916L (en)
NZ (1) NZ509867A (en)
PE (1) PE20001063A1 (en)
PL (1) PL346267A1 (en)
TR (1) TR200100672T2 (en)
TW (1) TW572757B (en)
UY (1) UY25677A1 (en)
WO (1) WO2000010566A1 (en)
ZA (1) ZA200101505B (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
GB0009803D0 (en) 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
US6465456B2 (en) 2000-06-29 2002-10-15 Bristol-Myers Squibb Company Isoxazolinone antibacterial agents
JP2002020366A (en) * 2000-07-05 2002-01-23 Sumitomo Seika Chem Co Ltd Method for producing alkylthiophenylacetic acid
PE20030044A1 (en) 2000-11-17 2003-02-09 Upjohn Co BICYCLE ISOXAZOLINONES OF FORMULA I
PE20020689A1 (en) 2000-11-17 2002-08-03 Upjohn Co OXAZOLIDINONES WITH A HETEROCYCLE OF 6 OR 7 MEMBERS UNITED WITH ANNULAR LINK TO BENZENE
US6861433B2 (en) 2000-12-15 2005-03-01 Pharmacia & Upjohn Company Oxazolidinone photoaffinity probes
EP1349853B1 (en) 2000-12-21 2006-03-08 Pharmacia & Upjohn Company LLC Antimicrobial quinolone derivatives and use of the same to treat bacterial infections
ES2180456B1 (en) * 2001-07-20 2004-05-01 Laboratorios S.A.L.V.A.T., S.A. SUBSTITUTED ISOXAZOLS AND ITS USE AS ANTIBIOTICS.
WO2003031443A1 (en) 2001-10-04 2003-04-17 Morphochem Aktiengesellschaft für kombinatorische Chemie Dual actions antibiotics comprising a oxazoldinone and a quinolone or naphthyridinone moiety
US7022705B2 (en) 2001-10-25 2006-04-04 Astrazeneca Ab Isoxazoline derivatives useful as antimicrobials
US6875784B2 (en) 2002-10-09 2005-04-05 Pharmacia & Upjohn Company Antimibicrobial [3.1.0.] bicyclic oxazolidinone derivatives
AU2003265090A1 (en) 2002-10-10 2004-05-04 Pharmacia & Upjohn Comapny LLC Antimicrobial 1-aryl dihydropyridone compounds
WO2004069832A2 (en) * 2003-02-07 2004-08-19 Warner-Lambert Company Llc Antibacterial agents
EP1620098B1 (en) 2003-04-30 2008-06-11 Morphochem Aktiengesellschaft Für Kombinatorische Chemie Use of oxazolidinone-quinoline hybrid antibiotics for the treatment of anthrax and other infections
US8324398B2 (en) 2003-06-03 2012-12-04 Rib-X Pharmaceuticals, Inc. Process for the synthesis of biaryl oxazolidinones
EP1646617A2 (en) * 2003-06-03 2006-04-19 Rib-X Pharmaceuticals, Inc. Sulfonamide compounds and methods of making and using the same
MXPA05013132A (en) 2003-06-03 2006-05-25 Rib X Pharmaceuticals Inc Biaryl heterocyclic compounds and methods of making and using the same.
EP1664001A2 (en) * 2003-07-29 2006-06-07 Rib-X Pharmaceuticals, Inc. Biaryl heterocyclic amines, amides, and sulfur-containing compounds and methods of making and using the same
DE10340485B4 (en) * 2003-09-03 2015-05-13 Morphochem AG Aktiengesellschaft für kombinatorische Chemie Process for the preparation of oxazolidinone-quinolone hybrids
US7304050B2 (en) * 2003-09-16 2007-12-04 Pfizer Inc. Antibacterial agents
US7129259B2 (en) 2003-12-17 2006-10-31 Rib-X Pharmaceuticals, Inc. Halogenated biaryl heterocyclic compounds and methods of making and using the same
US8158797B2 (en) 2003-12-18 2012-04-17 Morphochem Aktiengesellschaft Fur Kombinatorische Chemie Oxazolidinone-quinolone hybrid antibiotics
AU2004299278C9 (en) 2003-12-18 2013-10-24 Morphochem Aktiengesellschaft Fuer Kombinatorische Chemie Oxazolidinone-quinolone hybrid antibiotics
WO2005082900A2 (en) * 2004-01-28 2005-09-09 Pharmacia & Upjohn Company Llc Oxazolidinone amidoximes as antibacterial agents
US8399660B2 (en) 2005-06-08 2013-03-19 Rib-X Pharmaceuticals, Inc. Process for the synthesis of triazoles
AT503354B1 (en) * 2006-02-22 2008-07-15 Dsm Fine Chem Austria Gmbh METHOD FOR THE PRODUCTION OF 3,4-DISUBSTITUTED PHENYL ACETIC ACIDS, AND NEW INTERMEDIATE COMPOUNDS
JP4518066B2 (en) * 2006-10-25 2010-08-04 宇部興産株式会社 Dialkoxynitrile derivative and process for producing the same
CN110423610B (en) * 2019-08-29 2023-05-12 浙江理工大学 A fluorescent probe for detecting two-photon mercury ions and its preparation method and use method

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2045049A1 (en) * 1970-09-11 1972-03-23 Dr Karl Thomae GmbH, 7950 Biberach New Nitrofurandenvate and processes for their production
US4000155A (en) * 1975-12-11 1976-12-28 Eli Lilly And Company Herbicidal 2-methyl-4-phenyl-5-pyrazolinones[and isoxazolinones]
NZ257031A (en) * 1992-12-08 1996-07-26 Upjohn Co Tropone substituted phenyloxazolidinone derivatives and anti-bacterial medicaments thereof
JPH11511467A (en) * 1995-09-15 1999-10-05 ファルマシア・アンド・アップジョン・カンパニー 5-amidomethyl α, β-saturated and unsaturated 3-arylbutyrolactone antibacterial agents
GB9521508D0 (en) * 1995-10-20 1995-12-20 Zeneca Ltd Chemical compounds
ES2186916T3 (en) * 1996-08-21 2003-05-16 Upjohn Co ISOXAZOLINE DERIVATIVES AS ANTIMICROBIAL AGENTS.

Also Published As

Publication number Publication date
JP2002523369A (en) 2002-07-30
WO2000010566A1 (en) 2000-03-02
BR9913225A (en) 2001-05-22
HUP0103433A3 (en) 2002-08-28
AU5783399A (en) 2000-03-14
EP1107756A1 (en) 2001-06-20
PE20001063A1 (en) 2000-12-24
TR200100672T2 (en) 2001-07-23
TW572757B (en) 2004-01-21
IL141542A0 (en) 2002-03-10
NO20010916L (en) 2001-04-10
CO5160266A1 (en) 2002-05-30
PL346267A1 (en) 2002-01-28
NZ509867A (en) 2003-08-29
EP1107756A4 (en) 2003-02-26
CN1314813A (en) 2001-09-26
CZ2001669A3 (en) 2001-08-15
AR020250A1 (en) 2002-05-02
KR20010072945A (en) 2001-07-31
ID27690A (en) 2001-04-19
CA2341271A1 (en) 2000-03-02
AU748750B2 (en) 2002-06-13
ZA200101505B (en) 2002-02-22
NO20010916D0 (en) 2001-02-23
HUP0103433A2 (en) 2002-01-28

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Legal Events

Date Code Title Description
ABAN Application deemed to be withdrawn (no publication fee paid)

Effective date: 20090609