US2100081A - Process for the production of preparations containing the active constituents of vegetable products - Google Patents

Description

Patented Nov. 23, 1937 rRocEss FORv THE PRODUCTION or PREPARATIONS CONTAINING THE AC- TIvE cONsTITUENTs or VEGETABLE PRODUCTS Gerhard Madaus, Dresden, Germany, assignor to the firm Dr. Madaus & 00., Itadebeul, Saxonia, Germany No Drawing.

Application May 23, 1935, Serial No. 23,072.: In Germany'February 4, 1935 r 2 Claims.

My invention relates to a process for the production 10f preparations containing the active constituents of vegetable products.

I The application Serial No. 3391, filed January 5 25, 1935 is a broad disclosure of a process for the production of vegetable products with the aid of sugar, which process consists in triturating the plants containing the active substances with noncrystallizable sugar or mixtures 1 0i sugar followed by drying in any well-known manner.

' Now, I have discovered that honey can be employed with particular advantage for the extrac- ,tion and fixation of the said active constituents.

It is already known it is true, to employ honey I as a basis for medicinal preparations, fennel honey having-beenproduced by the mixing of fennel syrup, refined honey and fennel-oil sugar. Rose honey, a decoction of an alcoholic extract of rose petals with honey and glycerine' is also known. Another method of producing preparations of honey leads to the oxym'els, whichare obtained by mixtures of'refined honey being concentrated with acetic vegetable extracts.

The process according to the present invention, however, has nothing in common with those methods, since the procedure, in v the older methods, always consists in first producing a vegetable extract infusion or syrup of any kind,

which is then, in turn, mixed with honey in a 30 second'workin'g stage.

In contradistinction thereto, the present process consists in trituratingthe fresh plants or portions thereof, containing the valuable active substances, together with honey. In this case the honey acts as in manifold ways, being first a medium for extracting the active volatile substances from the plants, and then a'medium for the fixation of these substances in the preparation.

The preparations obtained by the present (01. 167-82) i process can "afterwards he worked up for the desired purposes in any convenient manner. Thus it is directly feasible to dry the extracts, or fill them into starch capsules for use.

. Eim'mple] 5 kg. of Salvia oflicinalis are mechanically mixed with 5 kg. of refined honey and reduced together therewith in a disintegrator. The resulting product is divided into doses, and packed 10 in starch capsules, which, if desired, may be I wrapped'in tin-foil and, if necessary also may contain' preservatives.

Example II 2.5 kg. of fresh peppermint plants are disintegrated togetherwith 2.5 kg. of bee'hon'ey, in the manner set forth in Example 1, 30 g. of formic acid being added, whereupon the mixture isdried in a current of dry air at room tempera- 20 ture and divided into doses.

'- I claim:-

1. The process of producing preparations containing the active constituents of vegetable substances, which comprises triturating he fresh plants in the presence of honey, thereb preserving the volatile constituents of the fresh plants in the'finished product.

2. The process of producing preparations con- -taining the. active constituents of vegetable substances, which comprises triturating the fresh plants in the pres enceof honey thereby dispersing the honey in the plant substances, and then drying the resulting mixture in a. current of dry air at substantially room temperature thereby preserving the active volatile plant constituents. in the finished product.

. GERHARD MADAUS.