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US20150013476A1 - Electronic Pipette - Google Patents

Electronic Pipette Download PDF

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Publication number
US20150013476A1
US20150013476A1 US14/376,670 US201314376670A US2015013476A1 US 20150013476 A1 US20150013476 A1 US 20150013476A1 US 201314376670 A US201314376670 A US 201314376670A US 2015013476 A1 US2015013476 A1 US 2015013476A1
Authority
US
United States
Prior art keywords
pipette
touch screen
electronic
operations
user interface
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US14/376,670
Other languages
English (en)
Inventor
Juha Telimaa
Mikael Lind
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Thermo Fisher Scientific Oy
Original Assignee
Thermo Fisher Scientific Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47757640&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=US20150013476(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Thermo Fisher Scientific Oy filed Critical Thermo Fisher Scientific Oy
Assigned to THERMO FISHER SCIENTIFIC OY reassignment THERMO FISHER SCIENTIFIC OY ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: TELIMAA, JUHA, LIND, MIKAEL
Publication of US20150013476A1 publication Critical patent/US20150013476A1/en
Abandoned legal-status Critical Current

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/021Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B01L3/0237Details of electronic control, e.g. relating to user interface
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/021Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/021Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B01L3/0227Details of motor drive means
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/0286Ergonomic aspects, e.g. form or arrangement of controls
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/02Devices for withdrawing samples
    • G01N1/10Devices for withdrawing samples in the liquid or fluent state
    • G01N1/14Suction devices, e.g. pumps; Ejector devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/08Ergonomic or safety aspects of handling devices
    • B01L2200/087Ergonomic aspects
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14Process control and prevention of errors
    • B01L2200/143Quality control, feedback systems
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/02Identification, exchange or storage of information
    • B01L2300/024Storing results with means integrated into the container
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/02Identification, exchange or storage of information
    • B01L2300/025Displaying results or values with integrated means
    • B01L2300/027Digital display, e.g. LCD, LED

Definitions

  • the present invention relates to a pipette intended for use in the dosage of liquids and comprising an electronically operating control system with a user interface comprising an electronic display.
  • Pipettes used for liquid dosage in laboratories comprise a piston movable in a cylinder for aspiration of liquid into a tip container connected with the cylinder.
  • the volume is usually adjustable.
  • electronic pipettes whose piston is actuated by means of an electric motor and a control system associated with it.
  • electronic pipettes whose pistons are actuated by manual force and which comprise an electronic display only.
  • Electronic pipettes have a user interface for selection of the desired pipette function (e.g., direct or reverse pipetting), setting of the volume and for giving commands for performing operations.
  • the user interface has the necessary switches for input of the necessary settings and performance of the functions.
  • the user interface is connected to a display, by means of which the volume and other necessary data can be displayed.
  • the display can also show menus allowing data input in the control system.
  • U.S. Pat. No. 8,033,188 discloses an electronic pipette, which comprises menu driven software for controlling the information displayed on the user interface display, for inputting information to program the pipettor and for controlling the operation of the pipettor.
  • the user interface also comprises a circular touch pad for navigating the user interface display and for operating the pipette.
  • An electronic controllable pipette in accordance with the present invention is equipped with one or more touch screens by which the pipetting operations of the pipette are operated.
  • touch screen within context of this description means an electronic visual display that displays information and that can detect the presence and location of a touch within the display area.
  • the touch screens may be used as modifiable function keys or buttons by which the pipetting operations of pipette are controlled.
  • the touch screens may be equipped with pre-programmed icons for different operations of the pipette, whereby the icons define the active pressing areas of the touch screen for activating the related functions of the pipette. These icons may be moved to different places on the touch screen and/or on different touch screens of the pipette.
  • the size of the icons, or the active area of the touch screen for receiving a touch to activate selected operation may also be adjustable. Some areas of the touch screen or whole touch screen may also be adjusted to be inactive, so they may be used as support surfaces when operating the pipette.
  • Examples for pipetting operations to be covered with pre-programmable icons include ejecting the tip of the pipette, filling of the tip container, dispensing the tip container, and mixing action of the pipette, for example.
  • the touch screens may also be equipped with sliding functions, whereby, for example, the pipetting motion can be carried out by moving finger along the surface of the touch screen, which corresponds to a similar type of motion in manual pipettes.
  • this sliding function the piston of the pipette follows the movement of the finger in real time.
  • this sliding function can be used to activate pipette's mixing function, for example.
  • the touch screens of the electronic pipette in accordance with one embodiment of the present invention may also be curved, so that they may follow the curved surfaces of the pipette.
  • an electronic pipette in accordance with one embodiment of the present invention, it is possible to change locations of areas registering pressing or touching for operating the pipette to be suitable for different users and for different hands, thereby minimizing the stress caused to the hand when operating the pipette.
  • the present invention also makes it possible to easily switch the locations of the pressing or touching areas, for example, for different fingers, during the use of the pipette, which makes it possible to minimize further the stresses caused by pipetting.
  • the electronic pipette in accordance with one embodiment of the present invention, may also be equipped with a programmable feature for monitoring the physical stresses caused by the use of the pipette, and based on the monitoring, for suggesting modifications or changes to the placements of pressing or touching areas in order to lower the physical stresses.
  • This programmable feature is advantageously part of the control software of the electronic pipette.
  • the present invention also allows a method for operating an electronic pipette, wherein the pipetting operations of the pipette are carried out by touching or pressing a touch screen, which touch screen is part of the user interface of the pipette.
  • the present invention also allows a use of a touch screen as a part of a user interface of an electronic pipette for operating pipetting operations of the pipette.
  • FIG. 1 shows an electronic pipette in accordance with one embodiment of the present invention
  • FIG. 2 shows the main touch screen areas of the pipette of FIG. 1 ,
  • FIG. 3 shows a functional diagram of an electronic pipette in accordance with one embodiment of the present invention
  • FIGS. 4A-4F show an example of operating an electronic pipette in accordance with one embodiment of the present invention
  • FIGS. 5A-5E show an example of changing positions of operations in setting mode of an electronic pipette in accordance with one embodiment of the present invention.
  • FIG. 6 shows examples of programmable icons for an electronic pipette in accordance with one embodiment of the present invention.
  • FIG. 1 shows an example of an electronic pipette 1 in accordance with one embodiment of the present invention.
  • a tip container (not shown) is attached to the lower end 2 on the pipette.
  • a piston movable in a cylinder Inside the pipette 1 is located a piston movable in a cylinder in order to aspire liquid into the tip container.
  • the piston of the pipette 1 is actuated by electric motor located within the pipette.
  • the pipette 1 is operated with a control system that have a user interface comprising, in this example, three touch screens 3 , 4 and 5 .
  • the pipette is gripped with hand from handle portion 6 , which handle portion also comprises at its upper end a finger support 7 .
  • the touch screens 4 can be operated with the index finger of the gripping hand and the touch screens 3 and 5 can be operated with the thumb of the gripping hand. Alternatively, the touch screens 3 , 4 and 5 can be operated with the fingers of the other hand.
  • the touch screen 3 on the pipette 1 is divided to several areas 8 - 12 each of which can be set to either purely present information, register pressing or touching and carry out certain action, or combination of these two. Further, each of the areas 8 - 12 , as well as the touch screens 4 and 5 or parts or these touch screens, can also be set to be inactive, for example, to be used as support surfaces.
  • Touch screens 3 , 4 and 5 or parts of them can also be set to register sliding functions, whereby, for example, the pipetting motion can be carried out by moving finger along the surface of the touch screen.
  • this sliding function the piston of the pipette follows the movement of the finger in real time.
  • this sliding function can be used to activate pipette's mixing function, for example.
  • Touch screens 3 , 4 and 5 also comprise pre-programmed icons for different pipetting operations, such as ejecting the tip of the pipette, filling of the tip container, dispensing the tip container, and mixing action of the pipette, for example. These icons advantageously identify the operation of the pressing or touching area as well as the active area related to this action.
  • FIG. 3 shows an example of a functional diagram of an electronic pipette, like the pipette 1 of FIG. 1 .
  • the operations of the pipette are controlled with a central processing unit (CPU), which is equipped with memory for storing pre-programmed operations and functions.
  • the user gives commands to the CPU through touch screens A-D of which in this example there are four.
  • the CPU is supplied with operating power by a battery and a voltage regulator, which can be recharged with a changer through charging connections when the pipette is placed in its stand.
  • the CPU of the pipette can also be connected to external databases through data interface.
  • the CPU receives information from and controls the pipette's piston reference position detector.
  • the CPU controls the motor of the pipette through a motor driver.
  • the dashed line on FIG. 3 presents boundary surface between the pipette itself and the stand of the pipette in which the pipette is placed when not in use.
  • FIGS. 4A-4F shows an example of operating an electronic pipette in accordance with one embodiment of the present invention.
  • the touch screens of the pipette are used to change the pipetting volume.
  • the user first touches the area of touch screen A showing the present pipetting volume, as shown in FIG. 4A .
  • This action activates the touch screen A to change its view to a numeric touchpad, where the present pipetting volume (235 ⁇ l) is shown near the upper edge of the touch screen A over the numeric touchpad, and below the numeric touchpad is an area for a new pipetting volume.
  • the user inputs the new pipetting volume, as is shown in FIG. 4B .
  • the user accepts the new pipetting volume by touching the area showing the newly input pipetting volume, as shown in FIG. 4C .
  • the touch screen A After the new pipetting volume is accepted, the touch screen A returns to the previous view where the pipetting volume has now changed to the new pipetting volume (73 ⁇ l) as shown in FIG. 4D .
  • the touch pad A identified with word “FILL” By touching or pressing the area of the touch pad A identified with word “FILL”, as shown in FIG. 4D , the user fills the tip of the pipette with set pipetting volume of 73 ⁇ l. Since the tip of the pipette now contains liquid, the area of the touch screen A, previously identified with word “FILL,” is changed to be identified with word “Dispense” by the control system of the pipette automatically and the operation activated by touching or pressing that area is changed correspondingly. Now, when the area with word “Dispense” is touched or pressed by the user, as is shown in FIG.
  • the user touches or presses a separate touch screen B, as shown in FIG. 4F , which touch screen B is set to activate the tip ejecting operation. The user is informed of this operation with the word “EJECT” located in the touch screen B.
  • FIGS. 5A-5E shows an example of changing positions of operations in setting mode of an electronic pipette in accordance with one embodiment of the present invention.
  • the selected “EJECT” tab in touch screen B can be moved by activating it with a touch, as is shown in FIG. 5A . After activating the selected tab, it can then be moved out of the area of the touch screen B by moving finger along the touch screen B to the edge of the touch screen, as is shown in FIG. 5B . After the selected “EJECT” tab is moved out of the touch screen B, a touch screen where the tab is to be moved, in this case touch screen A, is activated by touching or pressing the touch screen, as is shown in FIG. 5C . Then the selected “EJECT” tab can be dragged to a selected location within touch screen A, as is shown in FIG. 5D . By releasing the tab, a new position for it within the touch screen B is set, as shown in FIG. 5E .
  • FIG. 6 shows examples with pre-programmable icons for operations of an electronic pipette in accordance with one embodiment of the present invention. As can be seen from the figure, these icons advantageously also contain clarifying words relating to the operations activated by touching the icon in question in the touch screen of the pipette.

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Human Computer Interaction (AREA)
  • Physics & Mathematics (AREA)
  • Hydrology & Water Resources (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
  • User Interface Of Digital Computer (AREA)
  • Position Input By Displaying (AREA)
US14/376,670 2012-02-13 2013-02-08 Electronic Pipette Abandoned US20150013476A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FI20125149 2012-02-13
FI20125149 2012-02-13
PCT/FI2013/050142 WO2013121097A1 (fr) 2012-02-13 2013-02-08 Pipette électronique

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
PCT/FI2013/050142 A-371-Of-International WO2013121097A1 (fr) 2012-02-13 2013-02-08 Pipette électronique

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US17/526,095 Continuation US20220072531A1 (en) 2012-02-13 2021-11-15 Electronic pipette

Publications (1)

Publication Number Publication Date
US20150013476A1 true US20150013476A1 (en) 2015-01-15

Family

ID=47757640

Family Applications (5)

Application Number Title Priority Date Filing Date
US14/376,670 Abandoned US20150013476A1 (en) 2012-02-13 2013-02-08 Electronic Pipette
US14/377,308 Active 2033-08-16 US9522395B2 (en) 2012-02-13 2013-02-13 Pipette with a tracking system
US15/383,178 Active US10105698B2 (en) 2012-02-13 2016-12-19 Pipette with a tracking system
US16/164,152 Abandoned US20190046970A1 (en) 2012-02-13 2018-10-18 Pipette With A Tracking System
US17/526,095 Abandoned US20220072531A1 (en) 2012-02-13 2021-11-15 Electronic pipette

Family Applications After (4)

Application Number Title Priority Date Filing Date
US14/377,308 Active 2033-08-16 US9522395B2 (en) 2012-02-13 2013-02-13 Pipette with a tracking system
US15/383,178 Active US10105698B2 (en) 2012-02-13 2016-12-19 Pipette with a tracking system
US16/164,152 Abandoned US20190046970A1 (en) 2012-02-13 2018-10-18 Pipette With A Tracking System
US17/526,095 Abandoned US20220072531A1 (en) 2012-02-13 2021-11-15 Electronic pipette

Country Status (5)

Country Link
US (5) US20150013476A1 (fr)
EP (2) EP2814612B1 (fr)
CN (3) CN104254397A (fr)
ES (1) ES2713392T3 (fr)
WO (2) WO2013121097A1 (fr)

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JP2018164866A (ja) * 2017-03-28 2018-10-25 株式会社アイカムス・ラボ 携帯端末装置及びプログラム
WO2020176079A1 (fr) * 2019-02-26 2020-09-03 Cellink Ab Systèmes et procédés pour évaluations optoélectroniques en temps réel de volume de fluide dans des systèmes de distribution de fluide
USD926224S1 (en) * 2018-10-11 2021-07-27 Brand Gmbh + Co Kg Laboratory device display screen with graphical user interface
US11186736B2 (en) 2018-10-10 2021-11-30 Cellink Ab Double network bioinks
US11826951B2 (en) 2019-09-06 2023-11-28 Cellink Ab Temperature-controlled multi-material overprinting
US11931966B2 (en) 2018-01-26 2024-03-19 Cellink Bioprinting Ab Systems and methods for optical assessments of bioink printability

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US10918112B2 (en) 2013-05-23 2021-02-16 Duke Manufacturing Co. Dough preparation apparatus and methods
WO2014190274A1 (fr) 2013-05-23 2014-11-27 Duke Manufacturing Co. Appareil et procédés de préparation d'aliment
JP6842242B2 (ja) * 2016-03-22 2021-03-17 株式会社アイカムス・ラボ 分注システム
PL3335795T3 (pl) * 2016-12-16 2019-09-30 Eppendorf Ag Sposób dozowania cieczy za pomocą pipety i strzykawki oraz pipeta do uruchamiania strzykawki do dozowania cieczy
CN111408421A (zh) * 2019-01-07 2020-07-14 苏州赛尼特格尔实验室科技有限公司 一种电子移液器的显示方法
CN111408418A (zh) * 2019-01-07 2020-07-14 苏州赛尼特格尔实验室科技有限公司 一种电子移液器及其精度控制方法
WO2021108112A1 (fr) 2019-11-27 2021-06-03 Corning Incorporated Écosystème connecté destiné à un environnement de laboratoire
WO2021211080A1 (fr) 2020-04-14 2021-10-21 Oezargun Mehmet Ali Micropipette multicanal fonctionnelle (plage de volume élevée)
US20240075469A1 (en) * 2021-01-25 2024-03-07 Eppendorf Se Hand-held pipetting device
JP7747759B2 (ja) * 2021-01-25 2025-10-01 エッペンドルフ・ソシエタス・エウロパエア 手持ち式ピペット装置

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CN104254397A (zh) 2014-12-31
US20150000429A1 (en) 2015-01-01
US10105698B2 (en) 2018-10-23
EP2814614A1 (fr) 2014-12-24
CN108031501B (zh) 2021-04-23
US20170100712A1 (en) 2017-04-13
CN104114281B (zh) 2017-03-22
EP2814612A1 (fr) 2014-12-24
CN104114281A (zh) 2014-10-22
ES2713392T3 (es) 2019-05-21
WO2013121109A1 (fr) 2013-08-22
CN108031501A (zh) 2018-05-15
US20190046970A1 (en) 2019-02-14
US9522395B2 (en) 2016-12-20
US20220072531A1 (en) 2022-03-10
WO2013121097A1 (fr) 2013-08-22

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