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US20070073160A1 - Light-guided transluminal catheter - Google Patents

Light-guided transluminal catheter Download PDF

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Publication number
US20070073160A1
US20070073160A1 US11/509,203 US50920306A US2007073160A1 US 20070073160 A1 US20070073160 A1 US 20070073160A1 US 50920306 A US50920306 A US 50920306A US 2007073160 A1 US2007073160 A1 US 2007073160A1
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United States
Prior art keywords
catheter
illumination
optic
light
source
Prior art date
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Abandoned
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US11/509,203
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English (en)
Inventor
Farhad Imam
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Boston Childrens Hospital
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Boston Childrens Hospital
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Filing date
Publication date
Application filed by Boston Childrens Hospital filed Critical Boston Childrens Hospital
Priority to US11/509,203 priority Critical patent/US20070073160A1/en
Assigned to CHILDREN'S MEDICAL CENTER CORPORATION reassignment CHILDREN'S MEDICAL CENTER CORPORATION ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: IMAM, FARHAD B.
Priority to EP13190328.8A priority patent/EP2710974A3/fr
Priority to PCT/US2006/034887 priority patent/WO2007032992A1/fr
Priority to CA002622458A priority patent/CA2622458A1/fr
Priority to EP06814290.0A priority patent/EP1931273B1/fr
Priority to AU2006291224A priority patent/AU2006291224A1/en
Publication of US20070073160A1 publication Critical patent/US20070073160A1/en
Priority to US12/053,210 priority patent/US8954134B2/en
Priority to US12/636,975 priority patent/US8078261B2/en
Priority to US13/316,925 priority patent/US20120083689A1/en
Abandoned legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/15003—Source of blood for venous or arterial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/22—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
    • A61B18/24—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor with a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3937—Visible markers
    • A61B2090/3945—Active visible markers, e.g. light emitting diodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150748—Having means for aiding positioning of the piercing device at a location where the body is to be pierced
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/153—Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
    • A61B5/1535—Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes comprising means for indicating vein or arterial entry

Definitions

  • the present invention is directed generally to medical devices and more particularly to a light-guided catheter with inside-out transcutaneous illumination and visualization of placement through the skin including a method to locate non-visible blood vessels for catheterization.
  • the vessel is initially identified via aspiration by a syringe with an attached hollow needle by a technique commonly referred to as the Seldinger technique.
  • Seldinger technique When blood is drawn into the syringe this indicates that the vessel has been found.
  • the syringe is then disengaged from the needle and the needle lumen is occluded to prevent a possible air embolism and/or to prevent excessive bleeding. Thereafter, confirmation of needle placement in the vein or artery can be assured by haemodynamic monitoring or checking for pulsatile blood flow.
  • a thin guide wire is introduced, typically through the syringe needle or other introducer device, into the interior of the blood vessel.
  • the needle/introducer device is then withdrawn leaving the guide wire within the vessel, wherein the guide wire projects outwardly beyond the surface of the skin.
  • a physician for catheter placement.
  • the simplest is to pass the catheter directly into the blood vessel directly over the guide wire.
  • the guide wire is then withdrawn, leaving the catheter in position within the vessel. Correct catheter tip placement may then be verified by x-ray procedures.
  • this technique is only possible in cases where the catheter is of a relatively small diameter and not significantly larger than the guide wire.
  • a dilator device may be first passed over the guide wire to enlarge the insertion hole. The catheter is then introduced over the dialator/guide wire, and the guide wire and dilator are withdrawn.
  • the technique may be rather routine and straightforward in cases where the patient's blood vessel is near the surface of the skin and is directly visible.
  • patients especially the elderly and newborns
  • the initial needle puncture may default to a hunt-and peck routine to find the elusive vessel.
  • the insertion of the catheter is usually a blind procedure with verification of correct catheter tip placement only confirmed after the fact by radiographic methods.
  • the present invention is directed to medical devices and more particularly to a light-guided catheter with inside-out transcutaneous illumination and visualization of placement through the skin for the purpose of allowing real-time visual guidance, including a method to locate non-visible blood vessels for catheterization.
  • One particular embodiment of the invention is directed to a method for transcutaneous viewing and guiding of intracorporeal catheters into a body that comprises inserting a catheter into the body having at least one lumen and internally illuminating the catheter with light capable of propagating through the blood and tissue to an external viewer outside of the body.
  • Another embodiment of the invention is directed to a method for transcutaneous viewing and guiding of intracorporeal catheters into a body that comprises inserting a catheter into the body having at least one lumen and inserting into the lumen a source of illumination capable of propagating through the blood and tissue to an external viewer outside of the body.
  • Another embodiment of the invention is directed to a method for transcutaneous viewing and guiding of intracorporeal/intraarterial catheters wherein the internally illuminated catheter emits light of a first color and further includes the step of inserting into the catheter lumen a second source of illumination of a second color different from the first color, both of the colors being capable of propagating through blood and tissue to an external viewer outside of the body, whereby the location of each illumination source can be discerned from outside the body.
  • Another embodiment of the invention is directed to a method for transcutaneous viewing and guiding of intracorporeal/ catheters wherein the internally illuminated catheter is made of a material opaque to visible light and the light emitting device extends beyond the distal end of the catheter.
  • Another embodiment of the invention is directed to a method of locating non-visible intracorporeal/ blood vessels for catheterization comprising illuminating candidate locations with light capable of inducing fluorescence from blood constituents and detecting fluorescent response from the blood constituents thereby selecting the potential site for catheterization based upon detection of a predetermined fluorescent signal.
  • Another embodiment of the invention is directed to a transcutaneously viewable catheter comprising a tubular member having an insertable end and a first channel along the length of the catheter.
  • the catheter has a removable illumination source in said channel having at least an illuminated end, the source being configured to be extendible through said channel and beyond said end so that when the source is inserted into the channel, the illumination is visible outside the body, and the end thereof can be visually located.
  • Another embodiment of the invention is directed to a transcutaneously viewable catheter wherein the tubular member is substantially opaque to light from the illumination source; so that when the removable source is extended beyond the end of the member, the illumination is visible outside the body.
  • Another embodiment of the invention is directed to a transcutaneously viewable catheter wherein the tubular member is partially transparent to light emitted by the illumination source; so that when the illumination source reaches the end of tubular member, an observer can detect the difference in level or color of light transmission as the illumination source exits the tubular member.
  • Another embodiment of the invention is directed to a transcutaneously viewable catheter wherein the illumination source is leaky and emits light along at least a portion of its length, whether discrete or continuous.
  • Another embodiment of the invention is directed to a transcutaneously viewable catheter wherein the illumination source emits more light at its end than elsewhere therealong, so that it is possible to easily discern its path and end from outside the body.
  • Another embodiment of the invention is directed to an apparatus for locating substantially non-visible intracorporeal/blood vessels for catheterization comprising a tubular member having an insertable end and a channel along the length thereof.
  • the apparatus has a removable illumination source insertable in the channel having an illuminated end configured to be extendible through the channel.
  • the illumination source is capable of emitting light of predetermined optical wavelengths to excite fluorescence from blood constituents including an optical channel to receive fluorescence from blood constituents and an optical detector coupled to the optical channel to measure the fluorescence from the blood constituents.
  • This embodiment could be incorporated into all other embodiments for facilitation of initial vessel identification and placement prior to catheter insertion and final optimization of final tip placement.
  • Another embodiment of the invention is directed to an apparatus for locating substantially non-visible intracorporeal/ blood vessels for catheterization wherein an appropriate illumination source would be used, such as a low-loss fiber optic conductor or light-emitting diode.
  • an appropriate illumination source such as a low-loss fiber optic conductor or light-emitting diode.
  • Another embodiment of the invention is directed to an apparatus for locating substantially non-visible intracorporeal/ blood vessels for catheterization wherein the optical channel simultaneously delivers the illumination energy to excite fluorescence and receives fluorescence from blood constituents.
  • Another embodiment of the invention is directed to an apparatus for locating substantially non-visible intracorporeal/ blood vessels for catheterization wherein the optical components include a separator, such as but not limited to a dichroic mirror, to separate illumination and fluorescence signals prior to the optical detector.
  • a separator such as but not limited to a dichroic mirror
  • Another embodiment of the invention is directed to a transcutaneously viewable catheter comprising a tubular member having an insertable end and a first channel along the length of the catheter, with a first optic having an end and being formed within the tubular member and running substantially the length thereof. At least a portion of the first optic is leaky and an illumination source is connected to the optic to provide illumination at least along a portion of the length of the catheter with an optimized color of light so that the illumination is visible outside the body.
  • Another embodiment of the invention is directed to a transcutaneously viewable catheter comprising a tubular member having an insertable end and a channel along the length of the catheter, with a first optic embedded within the tubular member and running substantially the length thereof and a second optic inserted into the catheter channel and running substantially the length thereof. At least a portion of both optics are leaky and separate illumination sources of distinguishable colors or intensities are connected to each optic so that when both are illuminated the location of the end of the second optic can be distinguished from the first optic.
  • a transcutaneously viewable catheter comprising a tubular member having an insertable end and a channel along the length of the catheter, with a first optic embedded within the tubular member and running substantially the length thereof and a second optic inserted into the catheter channel and running substantially the length thereof. At least a portion of both optics are leaky, the second optic being leaky only near its end, and separate illumination sources of distinguishable colors are connected to each optic so that when both are illuminated the location of the end of the second optic can be distinguished from the first optic.
  • Another embodiment of the invention is directed to a transcutaneously viewable catheter comprising a tubular member having a first and second optic embedded within the tubular member and running along the length of the catheter. At least a portion of both optics are leaky, the second optic being leaky proximate its end, and separate illumination sources of distinguishable colors are connected to each optic so that when both are illuminated the location of the end of the second optic can be distinguished from the first optic.
  • a transcutaneously viewable catheter comprising a tubular member having an insertable end and a first channel along the length of the catheter, with a first optic having an end and being formed within the tubular member and running substantially the length thereof. At least a portion of the first optic is leaky and an illumination source is connected to the optic to provide illumination at least along a portion of the length of the catheter with a predetermined color of light so that the illumination is visible outside the body.
  • the catheter further includes an enlongated radio opaque element having an end and being insertable through the first channel, so that the location of the end of the elongated element can be distinguished from the first optic and detected from outside the body.
  • Another embodiment of the invention is directed to a transcutaneously viewable catheter comprising a tubular member having a first and second optic embedded within the tubular member and running along the length of the catheter. At least a portion of both optics are leaky, the second optic being leaky proximate to its end, and separate illumination sources of distinguishable colors are connected to each optic so that when both are illuminated the location of the end of the second optic can be distinguished from the first optic.
  • the catheter further includes an enlongated radio opaque element having an end and being insertable through the first channel. In this manner, the location of the end of the elongated element can be detected either visually via fluorescence using the light-emitting optic, or by radio detection (X-ray fluoroscopy techniques) if the optic has been removed.
  • FIG. 1 shows a schematic representation of an optically opaque multi-lumen catheter device inserted into a patient's blood vessel with a fiber optic device inserted into a working channel of the catheter providing inside-out transcutaneous illumination near the distal end of the catheter.
  • FIG. 2 shows a schematic representation of an optically transparent multi-lumen catheter device inserted into a patient's blood vessel with a fiber optic device inserted into a working channel of the catheter providing inside-out transcutaneous illumination along the length of the catheter.
  • FIG. 3A shows a side-view of a multi-lumen catheter device with a fiber optic inserted into a working channel of the catheter wherein the catheter device is delivering optical radiation to the patient's blood vessel and receiving a fluorescent signal back from chemistry constituents within the patient's blood.
  • FIG. 3B is an enlargement of the fiber optic device depicted in FIG. 3A , highlighting the counter propagating excitation and fluorescent optical signals traversing the fiber optic device.
  • FIG. 4 is a top view (looking down) of the catheter device shown in FIG. 3A showing the catheter device laterally displaced from the underlying patient's blood vessel.
  • FIG. 5 is a top view (looking down) of the catheter device shown in FIG. 3A showing the catheter device directly centered over the underlying patient's blood vessel.
  • the present invention is directed to medical devices and more particularly to a light-guided catheter for direct visualization of placement through the skin.
  • the catheter may be placed intracorporeal (inside the body) by any of the catheterization techniques known to those skilled in the art, and the invention includes, but is not limited to intravenous, intraarterial, or intraluminal placement of the catheter.
  • FIG. 1 One embodiment of a light-guided transluminal catheter device 100 is depicted schematically in FIG. 1 .
  • a multi-lumen catheter 102 is shown having been inserted through the patient's skin 104 and into the blood vessel lumen 106 over the guidewire 108 via the usual insertion techniques (e.g., the Seldinger technique mentioned earlier).
  • a similar catheter without initial guidewire may also be inserted directly through the lumen of the puncturing needle. This is commonly done in the case of peripherally-inserted central catheters (PICC) inserted in an extremity such as the arm or leg and threaded all the way to the heart.
  • PICC peripherally-inserted central catheters
  • the surgeon may insert a fiber optical device 110 into an available working channel 112 of the multi-lumen catheter 102 .
  • the fiber optic device 110 may be used in lieu of the guidewire following the Seldinger technique described earlier. In this approach, the fiber optic device 110 is inserted through the hypodermic needle and the catheter 102 is introduced into the patient's blood vessel by sliding the catheter over the fiber optic device 110 .
  • the fiber optical device 110 may comprise a plurality of “leaky” optical fibers or other light radiating structures which may extend from the exposed end 114 of the catheter 102 to slightly protruding outward from the distal end 116 of the catheter 102 into the patient's blood vessel lumen 106 .
  • “leaky” optical fibers or other light radiating structures may extend from the exposed end 114 of the catheter 102 to slightly protruding outward from the distal end 116 of the catheter 102 into the patient's blood vessel lumen 106 .
  • leaky we refer to those optical fibers which radiate or scatter light energy radially outward continuously along at least a portion of the length, i.e. the lateral surface of the fiber.
  • light emitted would preferably be in the visible light range so that special detection equipment is not required.
  • Illuminating at least a portion of the length of the catheter is desirable, for example, when inserting the catheter it may be highly advantageous to “see” the lateral surface of the catheter when navigating a bend or curve in the patient's blood vessel, which is not uncommon when inserting an intracardiac or “central” catheter from a peripheral location, as in PICC (peripherally inserted central catheter) placement at a distal extremity and threaded toward the heart.
  • PICC peripheral inserted central catheter
  • the physician may get direct visual confirmation that the catheter is proceeding smoothly “around the bend” without complications. This should be interpreted to mean that a portion of the lateral surface of the catheter, which will be inserted into the body, is capable is emitting illumination.
  • Light emitting devices 113 may be optically coupled to the optical fibers 110 by means well known in the art of optical communications. For example, light output 111 from the light emitting devices 113 may be coupled into the optical fiber 110 via a focusing lens 115 or other light coupling components.
  • the light emitting devices 113 may be chosen from the list of lasers, light emitting diodes, tungsten-halogen lamps or other suitable light sources with appropriate optical wavelength outputs to be visible by the naked eye or an opto-electronic detector.
  • opto-electronic detectors which may be sensitive to non-visible wavelengths (infrared, ultraviolet, etc.) appropriate alternative light sources and optical fibers may be utilized to generate, guide, and ultimately detect non-visible wavelengths emanating from the fibers.
  • the red wavelengths seem to be the most effective ( ⁇ 625-680 nm), but 532 nm (green) also works sufficiently.
  • This general wavelength has the advantage of minimizing the amount of scattering and provides for more precise catheter localization as would the red range at, for example, 5 milliwatts (mw) of power.
  • preferred embodiments might include green (532 nm) and/or red (635 nm) wavelength light sources coupled to the optic, which in preliminary experiments in rabbits and neonatal humans have been able to penetrate >1 cm of tissue and therefore would be visible to the naked eye at depths of up to 1 cm below the skin surface with relatively low light power ( ⁇ 5 mw).
  • visible light is highly advantageous because no special detection equipment is needed other than perhaps dimming of the ambient room light, which is already routinely practiced in the ICU environment with traditional venous transilluminators to identify vessels for venipuncture and/or arterial puncture.
  • the outer surface 118 of the multi-lumen catheter device 102 may be optically opaque so that only optical radiation 119 emanating from that portion of the optical fiber protruding from the distal end of the catheter 116 may propagate outward through the luminal blood 106 /skin 104 regions ultimately to the surgeon's eyes 120 for direct viewing of the in-dwelling location of the catheter tip region 116 (this region being defined as the tip itself and a portion of the catheter extending away from the tip so that a sufficient portion of the catheter can be easily detected.
  • the tip region 116 this region being defined as the tip itself and a portion of the catheter extending away from the tip so that a sufficient portion of the catheter can be easily detected.
  • the light emitting devices 113 may be operated continuously, intermittently, or in pulsatile fashion to facilitate visibility through the luminal blood 106 /skin 104 regions. Given this, the physician may visually track the location of the distal end region of the catheter 116 as the catheter is maneuvered further upstream in the patient's blood vessel lumen 106 towards the ultimate targeted location. Alternatively, the physician may insert the fiber optical device 110 after the catheter 102 is initially inserted into the patient's blood vessel lumen 106 and guide the catheter 102 by viewing the illuminated distal tip 116 as mentioned above.
  • FIG. 2 An alternative embodiment 200 of the present invention is depicted schematically in FIG. 2 .
  • a multi-lumen catheter 202 is shown having been inserted through the patient's skin 204 and into the blood vessel 206 over the guidewire 208 via the usual insertion techniques (e.g., the Seldinger technique mentioned earlier).
  • the fiber optical device 210 may consist of a plurality of “leaky” optical fibers or other light radiating structures which may extend from the exposed end 214 of the catheter 202 to slightly protruding outward from the distal end 216 of the catheter 202 into the patient's blood vessel 206 .
  • Light emitting devices 213 may be optically coupled to the optical fibers 210 by means well known in the art of optical communications. The light emitting devices 213 may be chosen from the list of lasers, light emitting diodes, tungsten-halogen lamps or other suitable light sources with appropriate optical wavelength outputs to be visible by the naked eye.
  • the outer surface 218 of the multi-lumen catheter device 202 may be partially, segmentally, or entirely optically transparent so that optical radiation 219 emanating from the optical fiber may propagate outward along the entire length of the fiber/catheter through the blood 206 /skin 204 regions ultimately to the surgeon's eyes 220 for direct viewing of the in-dwelling location of the catheter 202 .
  • the outer surface 218 may also modify the intensity, scatter, or wavelength of light passing through it such that the observer or detector would be able to discern the portion of the optic fiber extruded past the catheter tip from the potion lying within it.
  • the physician may visually track the location of the entire length of the catheter 202 as the catheter is maneuvered further upstream in the patient's blood vessel 206 towards the ultimate targeted location.
  • the physician may insert the fiber optical device 210 after the catheter 202 is initially inserted into the patient's blood vessel 206 and guide the catheter 202 by viewing the illuminated catheter as mentioned above.
  • the fiber optic device 210 may be inserted into an available working channel 212 of the multi-lumen catheter 202 as before, however, in this case prior to patient insertion the fiber end-face may be withdrawn a sufficient distance back into the distal end 216 of the catheter such that only the lateral surface 218 of the catheter is illuminated.
  • This configuration may eliminate the possibility of the fiber end-face irritating the wall of the patient's blood vessel as the catheter is being inserted, while still illuminating through the lateral surface of a translucent or otherwise non-opaque catheter, the lateral surface 218 of the catheter 202 during insertion and final placement.
  • the physician may utilize two individual optical fibers 210 to achieve this result.
  • one fiber may be either be pre-loaded into the catheter 202 flush with the distal end 216 of the catheter 202 or the fiber may be embedded in the wall of the catheter 202 terminating at the distal end 216 of the catheter 202 .
  • This fiber may be “leaky” along its length and when coupled with a blue LED light source 213 , for example, it may illuminate the entire sidewall of the catheter 202 with a blue tint, seen transcutaneously.
  • a second “non-leaky” optical fiber may be inserted into a working lumen of the catheter 202 and may be coupled to a green LED.
  • the transition from blue to green seen transcutaneously may serve as a marker identifying the location of the distal tip 216 of the catheter 202 .
  • different color light sources than the blue/green pair outlined above may be utilized to achieve similar results, wherein in all cases it is preferred that the light sources generate light visible to the naked eye.
  • An alternative embodiment to locate the distal tip 216 of the catheter 202 incorporates embedding two separate optical fibers in the wall of the catheter 202 .
  • the first optical fiber may be embedded in the wall of the catheter 202 terminating at the distal end 216 of the catheter 202 .
  • the first fiber may be “leaky” along its length and when coupled with a blue LED light source 213 , for example, it may illuminate the entire sidewall of the catheter 202 with a blue tint, seen transcutaneously.
  • a second “non-leaky” (i.e., optical energy only radiating from the distal end) fiber may also be imbedded in the wall of the catheter 202 terminating approximately an inch from the distal end 216 of the catheter 202 and may be coupled to a green LED.
  • the transition from a pure blue transcutaneous tint to a blue/green mixture may identify the location of the distal end region 216 of the intracorporeal catheter 202 .
  • different choices for the light sources may lead to acceptable alternative color combinations for transcutaneous viewing such as blue/white, green/white, yellow/blue and the like.
  • Another embodiment of the present invention comprises the combination of a fiber-illuminated catheter used in tandem with a traditional radio-opaque wire used in X-ray fluoroscopy.
  • a single or multiple lumen catheter may have the illuminating and/or radio-opaque fiber either embedded in the wall of the catheter or inserted in an available catheter lumen as before.
  • the radio-opaque wire may be inserted into a vacant catheter lumen or inserted into the same lumen as the illuminating fiber.
  • the illuminating fiber itself may also be radio-opaque (though another embodiment includes a radio-opaque fiber which will both provide propagation of light when connected to a source of illumination, but also be visulizable on radiographs)
  • the physician may multiplex back and forth between the two approaches as necessary. For example, an initial entry into the radial artery (arm) destined for the cardiac region may proceed as follows. Initial entry and threading in the arm may be guided directly by transcutaneous viewing of the fiber-illuminated catheter as outlined before. Upon entry into the chest cavity region, the physician may choose to switch to standard X-ray fluoroscopy when and if the visibility of the fiber-illumination becomes too faint to discern.
  • Another embodiment of the present invention encompasses a dual-purpose function of the illuminating fiber.
  • the illuminating optical fiber is inserted into an available lumen and illuminates the distal end of the catheter as previously outlined.
  • the fiber may have optically excited chemical sensors attached to the distal end of the fiber.
  • fluorescent dyes sensitive to the dissolved oxygen in blood (sometimes referred to as the partial pressure of oxygen in blood and designated as pO 2 ) are well known and historically have been encapsulated in a polymer membrane attached to the distal end of the sensing fiber.
  • additional fluorescent dyes have been demonstrated to respond to the dissolved carbon dioxide in blood (pCO 2 ) as well as the acidity (pH) of blood.
  • the additional ability to measure one or more of the “blood gases” while simultaneously viewing the illuminated catheter transcutaneously may allow the physician sufficient information to ascertain whether the catheter has been threaded into arterial or mixed venous blood, given that typical blood gas measurements for venous blood is discernibly different than arterial values.
  • PICC lines peripherally-inserted central catheters
  • umbilical artery and vein catheters used in the neonatal intensive care units.
  • PICC lines are commonly introduced into the patient's arm or leg through the lumen of the puncturing needle and threaded all the way to the patient's heart.
  • the PICC lines are subject to being misrouted when inserted and guided (threaded) blindly, and with direct transcutaneous viewing of the catheter while threading, this may be alleviated.
  • the direct transcutaneous viewing of the catheter while threading may be ideal for newborn infants with inherently thin skin, and may also be applicable to a large segment of the adult population, especially the elderly.
  • FIG. 3A shows a catheter 300 configured to function as an artery or vein-finder device to optically locate blood vessels which may not be visible directly by the unaided eye.
  • a side view of a multi-lumen catheter 302 is shown in contact with a patient's skin 304 directly over the patient's blood vessel 306 .
  • An optical fiber 310 has been inserted into an available working channel 312 of the catheter 302 .
  • the optical fiber 310 may be similar to those currently used in optical communications (i.e., “non-leaky” in contrast to the “leaky” fibers depicted in FIGS.
  • Light emitting devices 313 may be optically coupled to the optical fibers 310 by means well known in the art of optical communications.
  • the light emitting devices 313 may be chosen from the list of lasers, light emitting diodes, tungsten-halogen lamps or other suitable light sources with appropriate optical wavelength outputs to excite optical fluorescence from chemistries in the underlying blood vessel.
  • the catheter 302 with inserted optics to excite and receive fluorescent signals from chemistries in the underlying blood vessel may serve as an artery/vein finder to identify the correct location for the initial needle stick (first step in Seldinger technique or in PICC placement) to facilitate the process of eventually placing the catheter in-dwelling.
  • first step in Seldinger technique or in PICC placement to facilitate the process of eventually placing the catheter in-dwelling.
  • Naturally occurring chemistries in human blood are well known to fluoresce when excited (illuminated) at a particular wavelength corresponding to the absorption band of that chemistry.
  • the molecule responds by emitting optical energy at a longer wavelength (i.e., lower energy state) than the exciting/illuminating energy.
  • optical energy i.e., lower energy state
  • blood constituents bilirubin and carotenoid chromophores are known to fluoresce in the spectral region near 450 nanometers when optically excited (illuminated) at 340 nanometers. Fluorescence form these molecules may be used to locate the position of underlying blood vessels as follows.
  • optical radiation 311 may be chosen to emit optical radiation 311 near 340 nanometers (corresponding to the absorption band of bilirubin for example) which may be coupled into optical fiber 310 which guides the optical radiation 311 to the patient's skin surface 304 .
  • the optical radiation 311 may penetrate through the patient's skin 304 , traverse the blood vessel wall, enter the patient's blood stream and eventually interact (be absorbed by) a bilirubin molecule 314 present in the patient's blood stream. Thereafter, the bilirubin molecule 314 may re-radiate a fluorescent optical signal 316 (see the expanded view of the fiber 310 shown in FIG. 3B ), a portion of which may be coupled back into the optical fiber 310 and guided back toward the light source 313 .
  • the returning fluorescent signal 316 may be reflected by partial mirror 318 to optical detector 320 which may have optical filters embedded to only respond to the 340 nanometer signal indicative of bilirubin/blood fluorescence.
  • optical detector 320 would receive the maximum fluorescent signal back from the bilirubin molecule 314 , when the catheter 302 /fiber 310 device is directly placed over the underlying blood vessel 306 .
  • FIG. 4 shows a top view (looking down on the device depicted in FIG. 3 ) of the catheter 402 depicting the fiber 410 inserted in the working channel on the right hand side of the catheter 402 .
  • the catheter is shown displaced vertically, i.e., off-set from directly over the underlying blood vessel 406 , and as such the fluorescent signal 316 (from FIG. 3 ) capture by the optical fiber 410 will be relatively small.
  • the catheter 502 can be manually positioned back-and-forth until a maximum fluorescent signal 316 ( FIG. 3 ) is detected by the optical detector 320 signifying the blood vessel 506 has been located. This process can be repeated at several adjacent points to delineate the course of the vessel subcutaneously and further aid with correct insertion.
  • the present invention is directed generally to medical devices and more particularly to a light-guided catheter with inside-out transcutaneous illumination and visualization of placement through the skin including a method to locate non-visible blood vessels for catheterization.

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US11/509,203 2005-09-13 2006-08-24 Light-guided transluminal catheter Abandoned US20070073160A1 (en)

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US11/509,203 US20070073160A1 (en) 2005-09-13 2006-08-24 Light-guided transluminal catheter
AU2006291224A AU2006291224A1 (en) 2005-09-13 2006-09-07 Light-guided transluminal catheter
EP06814290.0A EP1931273B1 (fr) 2005-09-13 2006-09-07 Cathéter transluminal guidé par la lumière
PCT/US2006/034887 WO2007032992A1 (fr) 2005-09-13 2006-09-07 Catheter transluminal guide par la lumiere
CA002622458A CA2622458A1 (fr) 2005-09-13 2006-09-07 Catheter transluminal guide par la lumiere
EP13190328.8A EP2710974A3 (fr) 2005-09-13 2006-09-07 Cathéter transluminal guidé par la lumière
US12/053,210 US8954134B2 (en) 2005-09-13 2008-03-21 Light-guided transluminal catheter
US12/636,975 US8078261B2 (en) 2005-09-13 2009-12-14 Light-guided transluminal catheter
US13/316,925 US20120083689A1 (en) 2005-09-13 2011-12-12 Light-guided transluminal catheter

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US71645405P 2005-09-13 2005-09-13
US11/509,203 US20070073160A1 (en) 2005-09-13 2006-08-24 Light-guided transluminal catheter

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US12/053,210 Continuation-In-Part US8954134B2 (en) 2005-09-13 2008-03-21 Light-guided transluminal catheter
US12/636,975 Continuation US8078261B2 (en) 2005-09-13 2009-12-14 Light-guided transluminal catheter

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US11/509,203 Abandoned US20070073160A1 (en) 2005-09-13 2006-08-24 Light-guided transluminal catheter
US12/636,975 Expired - Fee Related US8078261B2 (en) 2005-09-13 2009-12-14 Light-guided transluminal catheter
US13/316,925 Abandoned US20120083689A1 (en) 2005-09-13 2011-12-12 Light-guided transluminal catheter

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US13/316,925 Abandoned US20120083689A1 (en) 2005-09-13 2011-12-12 Light-guided transluminal catheter

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Cited By (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050096642A1 (en) * 2003-10-31 2005-05-05 Appling William M. Endovascular treatment apparatus and method
US20060036164A1 (en) * 2001-06-19 2006-02-16 The Trustees Of The University Of Pennsylvania Optically guided system for precise placement of a medical catheter in a patient
US20070276258A1 (en) * 2006-03-28 2007-11-29 Crane Robert L Synchronization of Illumination Source and Sensor for Improved Visualization of Subcutaneous Structures
US20080177174A1 (en) * 2006-10-11 2008-07-24 Crane Robert L Determining Inserted Catheter End Location and Orientation
US20080194973A1 (en) * 2005-09-13 2008-08-14 Imam Farhad B Light-guided transluminal catheter
US20080208180A1 (en) * 2002-07-10 2008-08-28 Cartier William A Endovascular treatment sheath having a heat insulative tip and method for using the same
US20080228066A1 (en) * 2007-03-14 2008-09-18 Waitzman Kathryn A Mckenzie Methods and systems for locating a feeding tube inside of a patient
WO2009021064A1 (fr) * 2007-08-06 2009-02-12 University Of Rochester Dispositifs médicaux incorporant des colorants
JP2009031262A (ja) * 2007-06-22 2009-02-12 Canon Inc 生体情報イメージング装置
US20100063376A1 (en) * 2007-01-23 2010-03-11 Kartush Jack M Nerve monitoring device
US20100145178A1 (en) * 2007-01-23 2010-06-10 Kartush Jack M Nerve monitoring device
US20100262079A1 (en) * 2009-04-13 2010-10-14 Tyco Healthcare Group Lp Bendable veress needle assembly
US20100317956A1 (en) * 2007-01-23 2010-12-16 Kartush Jack M Nerve monitoring device
US20110009737A1 (en) * 2009-06-09 2011-01-13 The General Hospital Corporation Method and apparatus for dermatological treatment and tissue reshaping
US8078261B2 (en) 2005-09-13 2011-12-13 Children's Medical Center Corporation Light-guided transluminal catheter
US20130046172A1 (en) * 2007-03-14 2013-02-21 Kathryn A. McKenzie Waitzman Methods and systems for locating a feeding tube inside of a person
US20130296657A1 (en) * 2012-05-03 2013-11-07 Covidien Lp Methods of using light to repair hernia defects
WO2014029423A1 (fr) 2012-08-21 2014-02-27 Optomeditech Oy Ensemble cathéter intravasculaire
WO2014029421A1 (fr) 2012-08-21 2014-02-27 Optomeditech Oy Ensemble aiguille de prélèvement sanguin comportant une source lumineuse
US20150031987A1 (en) * 2013-07-24 2015-01-29 Cook Medical Technologies Llc Locating device
US20160256646A1 (en) * 2013-10-07 2016-09-08 Endoclear Llc Systems and methods for selectively blocking respiratory air flow
US9504403B2 (en) 2011-09-09 2016-11-29 The Magstim Company Limited Nerve sensing/monitoring device
US20170143236A1 (en) * 2013-09-20 2017-05-25 Children's National Medical Center Systems and methods for optically guided placement and monitoring of medical implants
US9814513B2 (en) 2011-06-30 2017-11-14 Angiodynamics, Inc. Endovascular plasma treatment device and method of use
US9907624B2 (en) 2009-02-06 2018-03-06 Endoclear Llc Body-inserted tube cleaning with suction
US10016575B2 (en) 2014-06-03 2018-07-10 Endoclear Llc Cleaning devices, systems and methods
US10238453B2 (en) 2002-07-10 2019-03-26 Angiodynamics, Inc. Method of making an endovascular laser treatment device for causing closure of a blood vessel
US20190134364A1 (en) * 2009-06-05 2019-05-09 Entellus Medical, Inc. Method and articles for treating the sinus system
US10682203B2 (en) 2009-02-06 2020-06-16 Endoclear Llc Methods of cleaning endotracheal tubes including light treatment
US10722322B2 (en) 2010-03-29 2020-07-28 Endoclear Llc Distal airway cleaning devices
RU2734284C2 (ru) * 2017-10-20 2020-10-14 Общество С Ограниченной Ответственностью "Рубикон" Трансиллюминатор для вен
US10821249B2 (en) 2012-12-04 2020-11-03 Endoclear Llc Closed suction cleaning devices, systems and methods
CN113082454A (zh) * 2016-03-28 2021-07-09 贝克顿·迪金森公司 具有发光光纤的套管
US20220099560A1 (en) * 2016-06-15 2022-03-31 Sorin Group Italia S.R.L. Methods and devices for monitoring blood
JP2022523010A (ja) * 2019-01-18 2022-04-21 ベクトン・ディキンソン・アンド・カンパニー 血管検出のための静脈内治療システム
US11541214B2 (en) 2009-06-05 2023-01-03 Entellus Medical, Inc. Balloon dilation catheter for use in sinus passageways
US11576724B2 (en) 2011-02-24 2023-02-14 Eximo Medical Ltd. Hybrid catheter for vascular intervention
WO2023103780A1 (fr) * 2021-12-10 2023-06-15 周星 Cathéter médical ayant un dispositif de suivi de lumière visible
US11684420B2 (en) 2016-05-05 2023-06-27 Eximo Medical Ltd. Apparatus and methods for resecting and/or ablating an undesired tissue
US12038322B2 (en) 2022-06-21 2024-07-16 Eximo Medical Ltd. Devices and methods for testing ablation systems
US12376904B1 (en) 2020-09-08 2025-08-05 Angiodynamics, Inc. Dynamic laser stabilization and calibration system

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9492175B2 (en) 2009-07-29 2016-11-15 University Of Florida Research Foundation, Inc. Apparatuses and methods for supporting an umbilicus
US9717553B2 (en) * 2010-12-29 2017-08-01 Biosence Webster (Israel) Ltd. Braid with integrated signal conductors
US9247906B2 (en) 2011-06-28 2016-02-02 Christie Digital Systems Usa, Inc. Method and apparatus for detection of catheter location for intravenous access
US8700133B2 (en) 2012-06-18 2014-04-15 Smart Iv Llc Apparatus and method for monitoring catheter insertion
US9597482B2 (en) 2012-06-18 2017-03-21 Smart Iv Llc Apparatus and method for monitoring catheter insertion
WO2015148859A1 (fr) 2014-03-26 2015-10-01 Venclose, Inc. Traitement de maladie veineuse
WO2017123764A1 (fr) * 2016-01-12 2017-07-20 Bloodworks, Llc Dispositif modulaire à sonde de mesure du sang intravasculaire par fibre optique périphérique et procédé associé
US10850046B2 (en) 2016-03-28 2020-12-01 Becton, Dickinson And Company Cannula locator device
US11478150B2 (en) 2016-03-28 2022-10-25 Becton, Dickinson And Company Optical fiber sensor
CN211884909U (zh) 2017-04-07 2020-11-10 巴德阿克塞斯系统股份有限公司 基于光纤的医疗设备跟踪和监测系统
GB201817046D0 (en) * 2018-10-19 2018-12-05 Breatnach Cormac A medical device
CN120203771A (zh) 2019-08-12 2025-06-27 巴德阿克塞斯系统股份有限公司 用于医疗装置的形状感测系统和方法
CN214804697U (zh) 2019-11-25 2021-11-23 巴德阿克塞斯系统股份有限公司 光学尖端追踪系统
CN112826480B (zh) 2019-11-25 2025-04-18 巴德阿克塞斯系统股份有限公司 具有滤波器的形状感测系统及其方法
US12246139B2 (en) 2020-02-28 2025-03-11 Bard Access Systems, Inc. Catheter with optic shape sensing capabilities
US11474310B2 (en) 2020-02-28 2022-10-18 Bard Access Systems, Inc. Optical connection systems and methods thereof
CN215608602U (zh) 2020-03-03 2022-01-25 巴德阿克塞斯系统股份有限公司 医疗设备和医疗设备监视系统
WO2021202589A1 (fr) 2020-03-30 2021-10-07 Bard Access Systems, Inc. Systèmes de diagnostic optique et électrique et procédés associés
CN216319408U (zh) 2020-06-26 2022-04-19 巴德阿克塞斯系统股份有限公司 错位检测系统
EP4171373A1 (fr) 2020-06-29 2023-05-03 Bard Access Systems, Inc. Référence de cadre tridimensionnel automatique pour fibre optique
CN113907705B (zh) 2020-07-10 2025-11-04 巴德阿克塞斯系统股份有限公司 连续光纤功能监测和自诊断报告系统
US12220255B2 (en) 2020-07-30 2025-02-11 Novotec Llc Vessel location assistance device
CN114052658B (zh) 2020-08-03 2025-12-16 巴德阿克塞斯系统股份有限公司 布拉格光栅光纤波动感测与监测系统
US20230355988A1 (en) * 2020-08-17 2023-11-09 Expanse Technology Partners, LLC Transvenous pacing system
EP4216819A1 (fr) 2020-09-25 2023-08-02 Bard Access Systems, Inc. Système d'oxymétrie à fibres optiques pour la détection et la confirmation
WO2022081586A1 (fr) 2020-10-13 2022-04-21 Bard Access Systems, Inc. Couvercles de désinfection pour connecteurs fonctionnels de dispositifs médicaux et procédés associés
CN114518075B (zh) 2020-11-18 2025-11-25 巴德阿克塞斯系统股份有限公司 光纤管心针保持器
CN217041033U (zh) 2020-11-24 2022-07-26 巴德阿克塞斯系统股份有限公司 用于将医疗器械插入患者体内的医疗器械系统
US12232821B2 (en) 2021-01-06 2025-02-25 Bard Access Systems, Inc. Needle guidance using fiber optic shape sensing
WO2022164902A1 (fr) 2021-01-26 2022-08-04 Bard Access Systems, Inc. Système de détection de forme de fibre optique associé à un placement de port
CN217960085U (zh) 2021-05-18 2022-12-06 巴德阿克塞斯系统股份有限公司 用于检测医疗设备在患者身体内的放置的医疗设备系统
CN219354146U (zh) 2021-09-16 2023-07-18 巴德阿克塞斯系统股份有限公司 连接部件
EP4418994A1 (fr) 2021-10-25 2024-08-28 Bard Access Systems, Inc. Plan de référence pour la mise en place de dispositif médical
US12318149B2 (en) 2022-03-08 2025-06-03 Bard Access Systems, Inc. Medical shape sensing devices and systems
US12426956B2 (en) 2022-03-16 2025-09-30 Bard Access Systems, Inc. Medical system and method for monitoring medical device insertion and illumination patterns
US12089815B2 (en) 2022-03-17 2024-09-17 Bard Access Systems, Inc. Fiber optic medical systems and devices with atraumatic tip
US20250195103A1 (en) * 2022-03-22 2025-06-19 Case Western Reserve University Methods, systems and apparatuses for transseptal procedures
US12343117B2 (en) 2022-06-28 2025-07-01 Bard Access Systems, Inc. Fiber optic medical systems and methods for identifying blood vessels
US12349984B2 (en) 2022-06-29 2025-07-08 Bard Access Systems, Inc. System, method, and apparatus for improved confirm of an anatomical position of a medical instrument

Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4567882A (en) * 1982-12-06 1986-02-04 Vanderbilt University Method for locating the illuminated tip of an endotracheal tube
US5217456A (en) * 1992-02-24 1993-06-08 Pdt Cardiovascular, Inc. Device and method for intra-vascular optical radial imaging
US5423321A (en) * 1993-02-11 1995-06-13 Fontenot; Mark G. Detection of anatomic passages using infrared emitting catheter
US5522389A (en) * 1990-09-28 1996-06-04 Hewlett-Packard Company System for measuring a blood parameter and method therefor
US5626134A (en) * 1994-04-21 1997-05-06 Zuckerman; Ralph Method and apparatus for the measurement of analyte concentration levels by the steady-state determination of fluorescence lifetime
US20020013616A1 (en) * 2000-05-05 2002-01-31 Andrew Carter Multilayer stents having enhanced flexibility and hoop strength
US20020127144A1 (en) * 2001-03-08 2002-09-12 Mehta Shailesh P. Device for analyzing particles and method of use
US20040092913A1 (en) * 2002-10-31 2004-05-13 Hennings David R. Endovenous closure of varicose veins with mid infrared laser
US20050070788A1 (en) * 2001-06-19 2005-03-31 Wilson David F Optical guidance system for invasive catheter placement
US6915154B1 (en) * 1999-09-24 2005-07-05 National Research Council Of Canada Method and apparatus for performing intra-operative angiography
US20060036164A1 (en) * 2001-06-19 2006-02-16 The Trustees Of The University Of Pennsylvania Optically guided system for precise placement of a medical catheter in a patient

Family Cites Families (123)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE393537B (sv) 1973-07-20 1977-05-16 Stille Werner Ab Anordning for inforande och styrning av en kateter eller liknande i haligheter eller blodkerl i kroppen pa en patient
US4096862A (en) 1976-05-17 1978-06-27 Deluca Salvatore A Locating of tubes in the human body
US4248214A (en) 1979-05-22 1981-02-03 Robert S. Kish Illuminated urethral catheter
US4875897A (en) 1981-06-12 1989-10-24 Regents Of University Of California Catheter assembly
US4444185A (en) 1981-08-19 1984-04-24 Shugar Martin A Fiberoptic tracheotomy method
US5435805A (en) 1992-08-12 1995-07-25 Vidamed, Inc. Medical probe device with optical viewing capability
US5370675A (en) 1992-08-12 1994-12-06 Vidamed, Inc. Medical probe device and method
US5306244A (en) 1984-05-14 1994-04-26 Surgical Systems & Instruments, Inc. Method of guidewire insertion
JPS61162956A (ja) 1985-01-11 1986-07-23 東レ株式会社 リ−クバル−ンカテ−テル
DE3650071T2 (de) 1985-03-22 1995-06-01 Massachusetts Inst Technology Katheter für Laserangiochirurgie.
US5104392A (en) 1985-03-22 1992-04-14 Massachusetts Institute Of Technology Laser spectro-optic imaging for diagnosis and treatment of diseased tissue
US5125404A (en) 1985-03-22 1992-06-30 Massachusetts Institute Of Technology Apparatus and method for obtaining spectrally resolved spatial images of tissue
US4917084A (en) 1985-07-31 1990-04-17 C. R. Bard, Inc. Infrared laser catheter system
EP0214712B1 (fr) * 1985-07-31 1992-09-02 C.R. Bard, Inc. Dispositif de cathéter à laser infrarouge
US5196004A (en) 1985-07-31 1993-03-23 C. R. Bard, Inc. Infrared laser catheter system
JPS62101261A (ja) 1985-10-28 1987-05-11 テルモ株式会社 医療器具導入用チユ−ブおよびそれを備えた医療器具導入用組立体
US4772093A (en) 1985-12-12 1988-09-20 Microvasive, Inc. Fiber-optic image-carrying device
GB2196100B (en) 1986-10-01 1990-07-04 Mitsubishi Rayon Co Light diffusing device
US4850358A (en) 1986-11-14 1989-07-25 Millar Instruments, Inc. Method and assembly for introducing multiple devices into a biological vessel
US4771782A (en) 1986-11-14 1988-09-20 Millar Instruments, Inc. Method and assembly for introducing multiple catheters into a biological vessel
US4966148A (en) 1986-11-14 1990-10-30 Millar Instruments, Inc. Assembly for positioning diagnostic devices in a biological vessel
JPH07108284B2 (ja) 1986-12-26 1995-11-22 オリンパス光学工業株式会社 体外観察装置
US4782819A (en) 1987-02-25 1988-11-08 Adair Edwin Lloyd Optical catheter
US5178616A (en) * 1988-06-06 1993-01-12 Sumitomo Electric Industries, Ltd. Method and apparatus for intravascular laser surgery
JP2542089B2 (ja) 1989-03-16 1996-10-09 オリンパス光学工業株式会社 内視鏡用光源装置
US4945895A (en) 1989-03-20 1990-08-07 Vance Products Incorporated Remote fiber optic medical procedure and device
US5179961A (en) 1989-04-13 1993-01-19 Littleford Philip O Catheter guiding and positioning method
US5054500A (en) 1989-04-13 1991-10-08 Littleford Philip O Catheter guiding and positioning method
US4934340A (en) 1989-06-08 1990-06-19 Hemo Laser Corporation Device for guiding medical catheters and scopes
US5019040A (en) 1989-08-31 1991-05-28 Koshin Sangyo Kabushiki Kaisha Catheter
US5005180A (en) 1989-09-01 1991-04-02 Schneider (Usa) Inc. Laser catheter system
US5005592A (en) 1989-10-27 1991-04-09 Becton Dickinson And Company Method and apparatus for tracking catheters
US5197470A (en) 1990-07-16 1993-03-30 Eastman Kodak Company Near infrared diagnostic method and instrument
US5005573A (en) 1990-07-20 1991-04-09 Buchanan Dale C Endotracheal tube with oximetry means
US5142155A (en) 1991-03-11 1992-08-25 Hewlett-Packard Company Catheter tip fluorescence-quenching fiber optic pressure sensor
US6134003A (en) 1991-04-29 2000-10-17 Massachusetts Institute Of Technology Method and apparatus for performing optical measurements using a fiber optic imaging guidewire, catheter or endoscope
US5131380A (en) 1991-06-13 1992-07-21 Heller Richard M Softwall medical tube with fiberoptic light conductor therein and method of use
US5263928A (en) 1991-06-14 1993-11-23 Baxter International Inc. Catheter and endoscope assembly and method of use
US7549424B2 (en) 1991-10-18 2009-06-23 Pro Surg, Inc. Method and apparatus for tissue treatment with laser and electromagnetic radiation
US5268570A (en) 1991-12-20 1993-12-07 Litton Systems, Inc. Transmission mode InGaAs photocathode for night vision system
DE4205336C1 (fr) 1992-02-21 1993-05-13 Gsf - Forschungszentrum Fuer Umwelt Und Gesundheit, Gmbh, 8000 Muenchen, De
US6785568B2 (en) 1992-05-18 2004-08-31 Non-Invasive Technology Inc. Transcranial examination of the brain
US5342299A (en) 1992-07-06 1994-08-30 Catheter Imaging Systems Steerable catheter
DE69325692T2 (de) 1992-08-18 2000-01-05 The Spectranetics Corp., Colorado Springs Führungsdraht mit Faseroptik
US5370640A (en) 1993-07-01 1994-12-06 Kolff; Jack Intracorporeal catheter placement apparatus and method
US5456680A (en) 1993-09-14 1995-10-10 Spectranetics Corp Fiber optic catheter with shortened guide wire lumen
US5415654A (en) 1993-10-05 1995-05-16 S.L.T. Japan Co., Ltd. Laser balloon catheter apparatus
US5417688A (en) 1993-12-22 1995-05-23 Elstrom; John A. Optical distal targeting system for an intramedullary nail
US5448582A (en) 1994-03-18 1995-09-05 Brown University Research Foundation Optical sources having a strongly scattering gain medium providing laser-like action
US5551946A (en) 1994-05-17 1996-09-03 Bullard; James R. Multifunctional intubating guide stylet and laryngoscope
US5733277A (en) 1994-06-22 1998-03-31 Pallarito; Allan L. Optical fibre and laser for removal of arterial or vascular obstructions
US6572609B1 (en) 1999-07-14 2003-06-03 Cardiofocus, Inc. Phototherapeutic waveguide apparatus
US5829444A (en) 1994-09-15 1998-11-03 Visualization Technology, Inc. Position tracking and imaging system for use in medical applications
US5517997A (en) 1994-09-15 1996-05-21 Gabriel Medical, Inc. Transillumination of body members for protection during body invasive procedures
US5728079A (en) 1994-09-19 1998-03-17 Cordis Corporation Catheter which is visible under MRI
US5735276A (en) * 1995-03-21 1998-04-07 Lemelson; Jerome Method and apparatus for scanning and evaluating matter
US6230046B1 (en) 1995-05-16 2001-05-08 The United States Of America As Represented By The Secretary Of The Air Force System and method for enhanced visualization of subcutaneous structures
US5672515A (en) 1995-09-12 1997-09-30 Optical Sensors Incorporated Simultaneous dual excitation/single emission fluorescent sensing method for PH and pCO2
US5947958A (en) 1995-09-14 1999-09-07 Conceptus, Inc. Radiation-transmitting sheath and methods for its use
US5803083A (en) 1995-11-09 1998-09-08 Cordis Corporation Guiding catheter with ultrasound imaging capability
US6174424B1 (en) 1995-11-20 2001-01-16 Cirrex Corp. Couplers for optical fibers
IL125757A (en) 1996-02-15 2003-09-17 Biosense Inc Medical procedures and apparatus using intrabody probes
US5728092A (en) 1996-03-07 1998-03-17 Miravant Systems, Inc. Light delivery catheter
US5868703A (en) 1996-04-10 1999-02-09 Endoscopic Technologies, Inc. Multichannel catheter
US6146409A (en) 1996-05-20 2000-11-14 Bergein F. Overholt Therapeutic methods and devices for irradiating columnar environments
US5879306A (en) 1996-06-13 1999-03-09 Stryker Corporation Infrared system for visualizing body members
US5904147A (en) 1996-08-16 1999-05-18 University Of Massachusetts Intravascular catheter and method of controlling hemorrhage during minimally invasive surgery
US5993382A (en) 1996-11-27 1999-11-30 Horizon Medical Products, Inc. Lighted catheter device and method for use and manufacture thereof
NL1005068C2 (nl) 1997-01-23 1998-07-27 Ct Rrn Academisch Ziekenhuis U Cathetersysteem en een daarvan deel uitmakende catheter.
WO1998040007A1 (fr) * 1997-03-13 1998-09-17 Biomax Technologies, Inc. Procede et dispositif de detection du rejet d'un tissu greffe
US6021247A (en) * 1997-05-09 2000-02-01 Helble; Robert Adjustable tap for light-pipe
US6061587A (en) 1997-05-15 2000-05-09 Regents Of The University Of Minnesota Method and apparatus for use with MR imaging
US6048349A (en) 1997-07-09 2000-04-11 Intraluminal Therapeutics, Inc. Systems and methods for guiding a medical instrument through a body
US6013072A (en) 1997-07-09 2000-01-11 Intraluminal Therapeutics, Inc. Systems and methods for steering a catheter through body tissue
FR2767703A1 (fr) 1997-09-04 1999-03-05 Medlight Sa Dispositif pour l'irradiation de cavites interieures de l'organisme
US5964757A (en) 1997-09-05 1999-10-12 Cordis Webster, Inc. Steerable direct myocardial revascularization catheter
US6402719B1 (en) 1997-09-05 2002-06-11 Cordis Webster, Inc. Steerable DMR catheter with infusion tube
US5902247A (en) 1997-09-09 1999-05-11 Bioenterics Corporation Transilluminating catheter
US5951482A (en) 1997-10-03 1999-09-14 Intraluminal Therapeutics, Inc. Assemblies and methods for advancing a guide wire through body tissue
US6659957B1 (en) 1998-03-05 2003-12-09 Gil M. Vardi Optical-acoustic imaging device
US6113588A (en) 1998-03-13 2000-09-05 Corvascular, Inc. Transillumination catheter and method
US6721582B2 (en) * 1999-04-06 2004-04-13 Argose, Inc. Non-invasive tissue glucose level monitoring
US5995208A (en) 1998-05-28 1999-11-30 Abbott Laboratories Intravascular oximetry catheter
US6081741A (en) 1998-06-05 2000-06-27 Vector Medical, Inc. Infrared surgical site locating device and method
US6095990A (en) 1998-08-31 2000-08-01 Parodi; Juan Carlos Guiding device and method for inserting and advancing catheters and guidewires into a vessel of a patient in endovascular treatments
US6701176B1 (en) 1998-11-04 2004-03-02 Johns Hopkins University School Of Medicine Magnetic-resonance-guided imaging, electrophysiology, and ablation
US6475226B1 (en) 1999-02-03 2002-11-05 Scimed Life Systems, Inc. Percutaneous bypass apparatus and method
US6167297A (en) 1999-05-05 2000-12-26 Benaron; David A. Detecting, localizing, and targeting internal sites in vivo using optical contrast agents
US6758830B1 (en) 1999-05-11 2004-07-06 Atrionix, Inc. Catheter positioning system
US6306097B1 (en) 1999-06-17 2001-10-23 Acuson Corporation Ultrasound imaging catheter guiding assembly with catheter working port
US6685666B1 (en) * 1999-11-12 2004-02-03 Mark G. Fontenot Catheters for breast surgery
US7137395B2 (en) * 2000-02-29 2006-11-21 The Johns Hopkins University Circumferential pulmonary vein ablation using a laser and fiberoptic balloon catheter
US6887229B1 (en) 2000-11-07 2005-05-03 Pressure Products Medical Supplies Inc. Method and apparatus for insertion of elongate instruments within a body cavity
US6519485B2 (en) 2000-12-13 2003-02-11 The General Hospital Corporation Minimally invasive system for assessment of organ function
US20020115922A1 (en) 2001-02-12 2002-08-22 Milton Waner Infrared assisted monitoring of a catheter
US8068898B2 (en) * 2001-03-01 2011-11-29 Trustees Of Dartmouth College Fluorescence lifetime spectrometer (FLS) and methods of detecting diseased tissues
DE60206742T2 (de) 2001-03-01 2006-04-27 Scimed Life Systems, Inc., Maple Grove Katheter mit fluoreszenztemperatursensoren
US6911017B2 (en) 2001-09-19 2005-06-28 Advanced Cardiovascular Systems, Inc. MRI visible catheter balloon
US20030092995A1 (en) 2001-11-13 2003-05-15 Medtronic, Inc. System and method of positioning implantable medical devices
US20030114732A1 (en) 2001-12-18 2003-06-19 Advanced Cardiovascular Systems, Inc. Sheath for guiding imaging instruments
EP1478295A2 (fr) 2002-02-05 2004-11-24 Pharmacyclics, Inc. Dispositif de transmission de lumiere faisant intervenir un systeme de diffusion conique et son procede de fabrication
US20040073120A1 (en) 2002-04-05 2004-04-15 Massachusetts Institute Of Technology Systems and methods for spectroscopy of biological tissue
US6704590B2 (en) 2002-04-05 2004-03-09 Cardiac Pacemakers, Inc. Doppler guiding catheter using sensed blood turbulence levels
US7647092B2 (en) 2002-04-05 2010-01-12 Massachusetts Institute Of Technology Systems and methods for spectroscopy of biological tissue
US6711426B2 (en) 2002-04-09 2004-03-23 Spectros Corporation Spectroscopy illuminator with improved delivery efficiency for high optical density and reduced thermal load
US6852109B2 (en) 2002-06-11 2005-02-08 Intraluminal Therapeutics, Inc. Radio frequency guide wire assembly with optical coherence reflectometry guidance
US7458967B2 (en) * 2003-10-31 2008-12-02 Angiodynamics, Inc. Endovascular treatment apparatus and method
CA2495562A1 (fr) 2002-08-05 2004-02-12 Steven J. Rychnovsky Catheter d'apport de lumiere
US20040068178A1 (en) 2002-09-17 2004-04-08 Assaf Govari High-gradient recursive locating system
US7535935B2 (en) 2002-09-27 2009-05-19 Infraredx, Inc. Spectroscopic catheter system with widely tunable source and method of operation
DE10245416B4 (de) 2002-09-28 2006-03-16 Pulsion Medical Systems Ag Kathetersystem mit besonderen Befestigungsmitteln
US20070248307A1 (en) 2002-10-04 2007-10-25 Page David J Transparent light emitting members and method of manufacture
US7964390B2 (en) * 2002-10-11 2011-06-21 Case Western Reserve University Sensor system
US10376711B2 (en) 2003-03-14 2019-08-13 Light Sciences Oncology Inc. Light generating guide wire for intravascular use
US20040236231A1 (en) 2003-05-23 2004-11-25 Embro Corporation Light catheter for illuminating tissue structures
WO2005057244A2 (fr) * 2003-08-19 2005-06-23 Cornell Research Foundation, Inc. Systeme de delivrance et de collecte de fibres optiques destine a des applications biologiques telles que le processus multiphotonique, spectroscopie et endoscopie
US7744604B2 (en) 2003-11-13 2010-06-29 Lawrence Livermore National Security, Llc Shape memory polymer medical device
US7654997B2 (en) 2004-04-21 2010-02-02 Acclarent, Inc. Devices, systems and methods for diagnosing and treating sinusitus and other disorders of the ears, nose and/or throat
US20060004317A1 (en) 2004-06-30 2006-01-05 Christophe Mauge Hydrocephalus shunt
US7225005B2 (en) * 2004-12-14 2007-05-29 Intelligent Medical Devices, Inc. Optical determination of in vivo properties
US7186011B2 (en) 2005-03-11 2007-03-06 Jean-Hway Lee Multiple point decorative light strip
US20070073160A1 (en) 2005-09-13 2007-03-29 Children's Medical Center Corporation Light-guided transluminal catheter
US8954134B2 (en) * 2005-09-13 2015-02-10 Children's Medical Center Corporation Light-guided transluminal catheter

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4567882A (en) * 1982-12-06 1986-02-04 Vanderbilt University Method for locating the illuminated tip of an endotracheal tube
US5522389A (en) * 1990-09-28 1996-06-04 Hewlett-Packard Company System for measuring a blood parameter and method therefor
US5217456A (en) * 1992-02-24 1993-06-08 Pdt Cardiovascular, Inc. Device and method for intra-vascular optical radial imaging
US5423321A (en) * 1993-02-11 1995-06-13 Fontenot; Mark G. Detection of anatomic passages using infrared emitting catheter
US5626134A (en) * 1994-04-21 1997-05-06 Zuckerman; Ralph Method and apparatus for the measurement of analyte concentration levels by the steady-state determination of fluorescence lifetime
US6915154B1 (en) * 1999-09-24 2005-07-05 National Research Council Of Canada Method and apparatus for performing intra-operative angiography
US20020013616A1 (en) * 2000-05-05 2002-01-31 Andrew Carter Multilayer stents having enhanced flexibility and hoop strength
US20020127144A1 (en) * 2001-03-08 2002-09-12 Mehta Shailesh P. Device for analyzing particles and method of use
US20050070788A1 (en) * 2001-06-19 2005-03-31 Wilson David F Optical guidance system for invasive catheter placement
US20060036164A1 (en) * 2001-06-19 2006-02-16 The Trustees Of The University Of Pennsylvania Optically guided system for precise placement of a medical catheter in a patient
US20040092913A1 (en) * 2002-10-31 2004-05-13 Hennings David R. Endovenous closure of varicose veins with mid infrared laser

Cited By (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060036164A1 (en) * 2001-06-19 2006-02-16 The Trustees Of The University Of Pennsylvania Optically guided system for precise placement of a medical catheter in a patient
US7992573B2 (en) * 2001-06-19 2011-08-09 The Trustees Of The University Of Pennsylvania Optically guided system for precise placement of a medical catheter in a patient
US10238453B2 (en) 2002-07-10 2019-03-26 Angiodynamics, Inc. Method of making an endovascular laser treatment device for causing closure of a blood vessel
US20080208180A1 (en) * 2002-07-10 2008-08-28 Cartier William A Endovascular treatment sheath having a heat insulative tip and method for using the same
US20050096642A1 (en) * 2003-10-31 2005-05-05 Appling William M. Endovascular treatment apparatus and method
US7458967B2 (en) * 2003-10-31 2008-12-02 Angiodynamics, Inc. Endovascular treatment apparatus and method
US8954134B2 (en) 2005-09-13 2015-02-10 Children's Medical Center Corporation Light-guided transluminal catheter
US20080194973A1 (en) * 2005-09-13 2008-08-14 Imam Farhad B Light-guided transluminal catheter
US8078261B2 (en) 2005-09-13 2011-12-13 Children's Medical Center Corporation Light-guided transluminal catheter
US8649848B2 (en) * 2006-03-28 2014-02-11 The United States Of America, As Represented By The Secretary Of The Air Force Synchronization of illumination source and sensor for improved visualization of subcutaneous structures
US20070276258A1 (en) * 2006-03-28 2007-11-29 Crane Robert L Synchronization of Illumination Source and Sensor for Improved Visualization of Subcutaneous Structures
US20080177174A1 (en) * 2006-10-11 2008-07-24 Crane Robert L Determining Inserted Catheter End Location and Orientation
US7917193B2 (en) * 2006-10-11 2011-03-29 The United States Of America As Represented By The Secretary Of The Air Force Determining inserted catheter end location and orientation
US8548572B2 (en) * 2006-10-11 2013-10-01 The United States Of America, As Represented By The Secretary Of The Air Force Determining inserted catheter end location and orientation
US20110270080A1 (en) * 2006-10-11 2011-11-03 Crane Robert L Determining inserted catheter end location and orientation
US20100063376A1 (en) * 2007-01-23 2010-03-11 Kartush Jack M Nerve monitoring device
US20100145178A1 (en) * 2007-01-23 2010-06-10 Kartush Jack M Nerve monitoring device
US8886280B2 (en) 2007-01-23 2014-11-11 The Magstim Company Limited Nerve monitoring device
US20100317956A1 (en) * 2007-01-23 2010-12-16 Kartush Jack M Nerve monitoring device
US20080228066A1 (en) * 2007-03-14 2008-09-18 Waitzman Kathryn A Mckenzie Methods and systems for locating a feeding tube inside of a patient
US20130046172A1 (en) * 2007-03-14 2013-02-21 Kathryn A. McKenzie Waitzman Methods and systems for locating a feeding tube inside of a person
US20100174197A1 (en) * 2007-06-22 2010-07-08 Canon Kabushiki Kaisha Biological information imaging apparatus
JP2009031262A (ja) * 2007-06-22 2009-02-12 Canon Inc 生体情報イメージング装置
WO2009021064A1 (fr) * 2007-08-06 2009-02-12 University Of Rochester Dispositifs médicaux incorporant des colorants
US20110017217A1 (en) * 2007-08-06 2011-01-27 University Of Rochester Medical apparatuses incorporating dyes
WO2009117727A1 (fr) * 2008-03-21 2009-09-24 Children's Medical Center Corporation Cathéter transluminal à guide lumineux
EP2268196A4 (fr) * 2008-03-21 2015-03-11 Childrens Medical Center Cathéter transluminal à guide lumineux
US10441380B2 (en) 2009-02-06 2019-10-15 Endoclear Llc Body-inserted tube cleaning
US10682203B2 (en) 2009-02-06 2020-06-16 Endoclear Llc Methods of cleaning endotracheal tubes including light treatment
US9962233B2 (en) 2009-02-06 2018-05-08 Endoclear Llc Body-inserted tube cleaning
US9907624B2 (en) 2009-02-06 2018-03-06 Endoclear Llc Body-inserted tube cleaning with suction
US20100262079A1 (en) * 2009-04-13 2010-10-14 Tyco Healthcare Group Lp Bendable veress needle assembly
US10561829B2 (en) * 2009-06-05 2020-02-18 Entellus Medical, Inc. Method and articles for treating the sinus system
US12064580B2 (en) 2009-06-05 2024-08-20 Entellus Medical, Inc. Method and articles for treating the sinus system
US11541214B2 (en) 2009-06-05 2023-01-03 Entellus Medical, Inc. Balloon dilation catheter for use in sinus passageways
US20190134364A1 (en) * 2009-06-05 2019-05-09 Entellus Medical, Inc. Method and articles for treating the sinus system
US11090472B2 (en) 2009-06-05 2021-08-17 Entellus Medical, Inc. Method and articles for treating the sinus system
US11083878B2 (en) 2009-06-05 2021-08-10 Entellus Medical, Inc. Method and articles for treating the sinus system
US12274847B2 (en) 2009-06-05 2025-04-15 Stryker Corporation Method and articles for treating the sinus system
US20110009737A1 (en) * 2009-06-09 2011-01-13 The General Hospital Corporation Method and apparatus for dermatological treatment and tissue reshaping
US10722322B2 (en) 2010-03-29 2020-07-28 Endoclear Llc Distal airway cleaning devices
US12042223B2 (en) 2011-02-24 2024-07-23 Eximo Medical Ltd. Hybrid catheter for vascular intervention
US11576724B2 (en) 2011-02-24 2023-02-14 Eximo Medical Ltd. Hybrid catheter for vascular intervention
US9814513B2 (en) 2011-06-30 2017-11-14 Angiodynamics, Inc. Endovascular plasma treatment device and method of use
US9504403B2 (en) 2011-09-09 2016-11-29 The Magstim Company Limited Nerve sensing/monitoring device
US20130296657A1 (en) * 2012-05-03 2013-11-07 Covidien Lp Methods of using light to repair hernia defects
US9186053B2 (en) * 2012-05-03 2015-11-17 Covidien Lp Methods of using light to repair hernia defects
US20150314105A1 (en) * 2012-08-21 2015-11-05 Optomeditech Oy Intravascular Catheter Assembly
US9700697B2 (en) * 2012-08-21 2017-07-11 Optomeditech Oy Intravascular catheter assembly
US20150201877A1 (en) * 2012-08-21 2015-07-23 Optomeditech Oy Blood collection needle assembly having a light source
US20170319825A1 (en) * 2012-08-21 2017-11-09 Optomeditech Oy Intravascular catheter assembly
WO2014029423A1 (fr) 2012-08-21 2014-02-27 Optomeditech Oy Ensemble cathéter intravasculaire
WO2014029421A1 (fr) 2012-08-21 2014-02-27 Optomeditech Oy Ensemble aiguille de prélèvement sanguin comportant une source lumineuse
US11173266B2 (en) 2012-12-04 2021-11-16 Endoclear Llc Closed suction cleaning devices, systems and methods
US10821249B2 (en) 2012-12-04 2020-11-03 Endoclear Llc Closed suction cleaning devices, systems and methods
US10602960B2 (en) * 2013-07-24 2020-03-31 Cook Medical Technologies Llc Locating device
US20150031987A1 (en) * 2013-07-24 2015-01-29 Cook Medical Technologies Llc Locating device
US20170143236A1 (en) * 2013-09-20 2017-05-25 Children's National Medical Center Systems and methods for optically guided placement and monitoring of medical implants
US20160256646A1 (en) * 2013-10-07 2016-09-08 Endoclear Llc Systems and methods for selectively blocking respiratory air flow
US10850062B2 (en) 2014-06-03 2020-12-01 Endoclear Llc Cleaning devices, systems and methods
US10016575B2 (en) 2014-06-03 2018-07-10 Endoclear Llc Cleaning devices, systems and methods
CN113082454A (zh) * 2016-03-28 2021-07-09 贝克顿·迪金森公司 具有发光光纤的套管
US11684420B2 (en) 2016-05-05 2023-06-27 Eximo Medical Ltd. Apparatus and methods for resecting and/or ablating an undesired tissue
US11994460B2 (en) * 2016-06-15 2024-05-28 Sorin Group Italia S.R.L. Methods and devices for monitoring blood
US20220099560A1 (en) * 2016-06-15 2022-03-31 Sorin Group Italia S.R.L. Methods and devices for monitoring blood
RU2734284C2 (ru) * 2017-10-20 2020-10-14 Общество С Ограниченной Ответственностью "Рубикон" Трансиллюминатор для вен
JP2022523010A (ja) * 2019-01-18 2022-04-21 ベクトン・ディキンソン・アンド・カンパニー 血管検出のための静脈内治療システム
US12376904B1 (en) 2020-09-08 2025-08-05 Angiodynamics, Inc. Dynamic laser stabilization and calibration system
WO2023103780A1 (fr) * 2021-12-10 2023-06-15 周星 Cathéter médical ayant un dispositif de suivi de lumière visible
US12038322B2 (en) 2022-06-21 2024-07-16 Eximo Medical Ltd. Devices and methods for testing ablation systems

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EP2710974A2 (fr) 2014-03-26
US20120083689A1 (en) 2012-04-05
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CA2622458A1 (fr) 2007-03-22
US8078261B2 (en) 2011-12-13
AU2006291224A1 (en) 2007-03-22

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