US1599023A - Method of and composition for producing local anesthesia in teeth - Google Patents
Method of and composition for producing local anesthesia in teeth Download PDFInfo
- Publication number
- US1599023A US1599023A US576849A US57684922A US1599023A US 1599023 A US1599023 A US 1599023A US 576849 A US576849 A US 576849A US 57684922 A US57684922 A US 57684922A US 1599023 A US1599023 A US 1599023A
- Authority
- US
- United States
- Prior art keywords
- cavity
- teeth
- composition
- adrenalin
- anesthetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000203 mixture Substances 0.000 title description 16
- 238000000034 method Methods 0.000 title description 11
- 238000002690 local anesthesia Methods 0.000 title description 5
- UCTWMZQNUQWSLP-VIFPVBQESA-N (R)-adrenaline Chemical compound CNC[C@H](O)C1=CC=C(O)C(O)=C1 UCTWMZQNUQWSLP-VIFPVBQESA-N 0.000 description 32
- ZPUCINDJVBIVPJ-LJISPDSOSA-N cocaine Chemical compound O([C@H]1C[C@@H]2CC[C@@H](N2C)[C@H]1C(=O)OC)C(=O)C1=CC=CC=C1 ZPUCINDJVBIVPJ-LJISPDSOSA-N 0.000 description 18
- UCTWMZQNUQWSLP-UHFFFAOYSA-N Adrenaline Natural products CNCC(O)C1=CC=C(O)C(O)=C1 UCTWMZQNUQWSLP-UHFFFAOYSA-N 0.000 description 16
- 229940102884 adrenalin Drugs 0.000 description 16
- 230000003444 anaesthetic effect Effects 0.000 description 13
- 229960003920 cocaine Drugs 0.000 description 9
- 230000036407 pain Effects 0.000 description 6
- 210000004268 dentin Anatomy 0.000 description 5
- 206010002091 Anaesthesia Diseases 0.000 description 4
- 230000037005 anaesthesia Effects 0.000 description 4
- 239000004568 cement Substances 0.000 description 4
- 238000005553 drilling Methods 0.000 description 4
- 238000011049 filling Methods 0.000 description 4
- 229960003771 cocaine hydrochloride Drugs 0.000 description 3
- PIQVDUKEQYOJNR-VZXSFKIWSA-N cocaine hydrochloride Chemical compound [Cl-].O([C@H]1C[C@@H]2CC[C@@H]([NH+]2C)[C@H]1C(=O)OC)C(=O)C1=CC=CC=C1 PIQVDUKEQYOJNR-VZXSFKIWSA-N 0.000 description 3
- 238000004040 coloring Methods 0.000 description 3
- 238000004140 cleaning Methods 0.000 description 2
- 239000003479 dental cement Substances 0.000 description 2
- 239000003589 local anesthetic agent Substances 0.000 description 2
- 210000005036 nerve Anatomy 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 230000035807 sensation Effects 0.000 description 2
- 210000004204 blood vessel Anatomy 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 210000004907 gland Anatomy 0.000 description 1
- YOBAEOGBNPPUQV-UHFFFAOYSA-N iron;trihydrate Chemical compound O.O.O.[Fe].[Fe] YOBAEOGBNPPUQV-UHFFFAOYSA-N 0.000 description 1
- 229910000464 lead oxide Inorganic materials 0.000 description 1
- YEXPOXQUZXUXJW-UHFFFAOYSA-N oxolead Chemical compound [Pb]=O YEXPOXQUZXUXJW-UHFFFAOYSA-N 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- IOVGROKTTNBUGK-SJCJKPOMSA-N ritodrine Chemical compound N([C@@H](C)[C@H](O)C=1C=CC(O)=CC=1)CCC1=CC=C(O)C=C1 IOVGROKTTNBUGK-SJCJKPOMSA-N 0.000 description 1
- 239000003566 sealing material Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/70—Preparations for dentistry comprising inorganic additives
- A61K6/78—Pigments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/60—Preparations for dentistry comprising organic or organo-metallic additives
- A61K6/69—Medicaments
Definitions
- This invention relates to methods of producing local anesthesia in teeth for thepurpose of filling cavities in teeth without pain to the patient, and also to a composition for cavity with the composition in place thereuse in carrying out this process.
- the objects of the invt'antion areto pro vide' an improved process for producing complete anesthesia in the vicinity of a a cavity in a tooth so that the cavity can be drilled out and filled Without pain to the patient; also to i provide a compositon for use-in cavities 'ofteeth to pro'ducefane'sthesia in the vicinity of the cavity also to improve methods and :compositions of this kind in other respects hereinafter specified,
- the composition also includes a coloring matter or dye such tor example as red oxide of lead,
- the portion of the tooth in which the cavity is located is then dried and a tablet of my compositionis inserted into the cavity, in; dry form. The.
- dental j cement preferably being used'and beingapplied to the cavity'in such a manner that all moisture will be excluded, since the composition is extremely soluble in water.
- Other cements ,or sealing inaterials'or compositions may housed in place of ordinary'dental cement, if desired.
- the cavity is completely sealed for a period of from two to four hours, depending upon the depth of the cavity, and after the lapse of this interval of time, the cement or other sealing material is removed from the cavity. It will be found that the moisture in the tooth has entirely dissolved the tablet ant the cavity is then in condition to be drilled out and filled. During the drilling and fill-- ing operations the patient has no sensation o l pain'and consequently much of-the dentists time is saved in the drilling and filling of the tooth.
- the anesthetic apparently acts mainly upon the minute fibrillm of the dentine and prevents these fibrillee from transmitting sensations of pain to the nerve of the tooth, although in the cases of a deep cavity, the
- nerve of a tooth may be partly aliected by n the anesthetic.
- the cocaine and adrenalin in the composition are apparently taken up by the moisture in the dentine of the tooth by osmosis and the action of the anesthetic continues for a considerable period of time, sometimes for more than an hour after the seal is removed, so that the dentist has plenty of available time in which to complete the drilling and filling of the cavity.
- the cocaine in the composition has the usual eifect of anesthetizing the portions adja'cent thereto and the adrenalin or similar composition is used for the purpose of con tracting the blood vessels in the vicinity of the cavity so as to prolong theanesthesia.
- the method and composition described have the advantages that owing to the fact that the action of'anesthesia is very local in its nature, no bad after-efiects of any kind occur and cavities of the'kind which i llO Theabsence of pain on the part of the pa 'tient makes it possible for the dentist to acout.
- the hereindescribed process 01" preparing cavities in teeth for treatment, consisting in eliectinga preliminary cleaning or the cavity, inserting into, the cavity a local anesthetic and adrenalin, placing over the cavity and the anesthetic and adrenalin therein a seal of dental cement to exclude moisture from the cavity, permittin the local anesthetic and adrenalin to be absorbed by osmosis by the dentine surrounding the cavity to anesthetize the tooth in the vicinity of the cavity, and then removing the seal after an interval of from tWO to four hours.
- composition for producing local anesthesia in teeth including cocaine and adrenalin in dry form and a pigment of a color vdiffering from that of adjacent parts of the teeth.
- composition for producing local anesthesia in teeth including cocaine hydrochloride and adrenalin in dry form in the proportions of two hundred parts of cocaine hydrochloride and one part of adrenalin and suflicient oxide of lead to give the composition a reddish color.
Landscapes
- Health & Medical Sciences (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
Description
Patented Sept. 7,. 1926,
UNITED-STATES PATENT OFFICE.
I wIL I M-rQncr nnEn, or MInnLnroa'r, NEW YORK ASSIGNOR or ONE-HALF 'ro rnanx r. BARRY, or nnr'norr, MICHIGAN;
Memos or AND coivrrosirion ron rnonnome LocAL ANESTHESIA IN TEETH.
No Drawing.
This invention relates to methods of producing local anesthesia in teeth for thepurpose of filling cavities in teeth without pain to the patient, and also to a composition for cavity with the composition in place thereuse in carrying out this process.
The objects of the invt'antion areto pro vide' an improved process for producing complete anesthesia in the vicinity of a a cavity in a tooth so that the cavity can be drilled out and filled Without pain to the patient; also to i provide a compositon for use-in cavities 'ofteeth to pro'ducefane'sthesia in the vicinity of the cavity also to improve methods and :compositions of this kind in other respects hereinafter specified,
Attempts have heretofore been made to produce'anesthesia in teeth by placing an anesthetic into the cavity tobe filled, but
none of these attempts have been successful -thatfthe efiiect wo'uld pass oil "before the drilling and fillingfof the cavitycould be completed. In carrying out my process, I employ a composition consisting Off cocaine in dry' or powder tor1n, miXed with adrenalin or some similar der vatlve of the superrenal glands,
in the proportions of approximately two hundred parts of cocaine to one part of adrenalin. form of small tablets which can be placed into the cavity of a tooth. Preferably the composition also includes a coloring matter or dye such tor example as red oxide of lead,
grainoof adrenalin. and trace of lead oxide,
can be verysuccessfully used, although it is not necessary to adhere to these propoi trons, since as much as one hall. grain 0t cocaine hydrochloride may be used and the quantity of adrenalin may be increased or decreased" as desired, V V In carrying outthe process embodying jmy invention, I first clean out the cavity in the usual manner as far asfpo'ssible ,withfor thereason that the'anesthesia was either incomplete or else of such short duration This mixture is pressed into the.
Application filed July 22,1922. Serial No. 576,849.
out causing any pain. The portion of the tooth in which the cavity is located is then dried and a tablet of my compositionis inserted into the cavity, in; dry form. The.
in isthen sealed in any suitable or desired inanner, dental j cement preferably being used'and beingapplied to the cavity'in such a manner that all moisture will be excluded, since the composition is extremely soluble in water. Other cements ,or sealing inaterials'or compositions may housed in place of ordinary'dental cement, if desired. The cavity is completely sealed for a period of from two to four hours, depending upon the depth of the cavity, and after the lapse of this interval of time, the cement or other sealing material is removed from the cavity. It will be found that the moisture in the tooth has entirely dissolved the tablet ant the cavity is then in condition to be drilled out and filled. During the drilling and fill-- ing operations the patient has no sensation o l pain'and consequently much of-the dentists time is saved in the drilling and filling of the tooth.
The anesthetic apparently acts mainly upon the minute fibrillm of the dentine and prevents these fibrillee from transmitting sensations of pain to the nerve of the tooth, although in the cases of a deep cavity, the
nerve of a tooth may be partly aliected by n the anesthetic. The cocaine and adrenalin in the composition are apparently taken up by the moisture in the dentine of the tooth by osmosis and the action of the anesthetic continues for a considerable period of time, sometimes for more than an hour after the seal is removed, so that the dentist has plenty of available time in which to complete the drilling and filling of the cavity.
The cocaine in the composition has the usual eifect of anesthetizing the portions adja'cent thereto and the adrenalin or similar composition is used for the purpose of con tracting the blood vessels in the vicinity of the cavity so as to prolong theanesthesia.
The method and composition described have the advantages that owing to the fact that the action of'anesthesia is very local in its nature, no bad after-efiects of any kind occur and cavities of the'kind which i llO Theabsence of pain on the part of the pa 'tient makes it possible for the dentist to acout.
I claim my invention:
1. The hereindescribed process 01" preparing cavities in teeth for treatment, consisting in eliectinga preliminary cleaning or the cavity, inserting into, the cavity a local anesthetic and adrenalin, placing over the cavity and the anesthetic and adrenalin therein a seal of dental cement to exclude moisture from the cavity, permittin the local anesthetic and adrenalin to be absorbed by osmosis by the dentine surrounding the cavity to anesthetize the tooth in the vicinity of the cavity, and then removing the seal after an interval of from tWO to four hours.
2. The hereindescribed process of prepar ing cavities in teeth for treatment, consisting in effecting a preliminary cleaning of the cavity, inserting into the cavity an anesthetic including cocaine and adrenalin in the proportions of approximately two hundred parts by Weight of cocaine to one part of adrenalin, placing oversaid cavity and the anesthetic thereina seahofdental cement to exclude moisture from the cavity, permitting the cocaine and adrenalin to be absorbed by the dentine surrounding the cavity by osmosis to anesthetize the tooth in the vicinity of the cavity, and then re moving the seal after an interval of from two to four hours.
The hereindescribed processoi preparing cavities in teeth for treatment, consisting in placing, intoa cavity a dry anesthetic in cluding a coloring matter, covering the cavity and the anesthetic therein With a seal to exclude moisture from the cavity, and permitting the anesthetic to act for a period of from two to four hours.
-l. The hereindescribed process of preparing cavities in teeth for treatment, consisting in inserting into the cavity an anesthetic in dry form, including cocaine and adrenalin and a coloring matter, sealing the cavity with the anesthetic'therein, permitting the anesthetic to be absorbed by the dentine of the tooth adjacent to the cavity, and then removing the seal.
5. The hereindescribed composition for producing local anesthesia in teeth, including cocaine and adrenalin in dry form and a pigment of a color vdiffering from that of adjacent parts of the teeth.
6. The hereindescribed composition for producing local anesthesia in teeth, including cocaine hydrochloride and adrenalin in dry form in the proportions of two hundred parts of cocaine hydrochloride and one part of adrenalin and suflicient oxide of lead to give the composition a reddish color.
WILLIAMD. B lcFADDEN.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US576849A US1599023A (en) | 1922-07-22 | 1922-07-22 | Method of and composition for producing local anesthesia in teeth |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US576849A US1599023A (en) | 1922-07-22 | 1922-07-22 | Method of and composition for producing local anesthesia in teeth |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| US1599023A true US1599023A (en) | 1926-09-07 |
Family
ID=24306253
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| US576849A Expired - Lifetime US1599023A (en) | 1922-07-22 | 1922-07-22 | Method of and composition for producing local anesthesia in teeth |
Country Status (1)
| Country | Link |
|---|---|
| US (1) | US1599023A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2129883C1 (en) * | 1998-07-08 | 1999-05-10 | Закрытое акционерное общество "Международная компания Дельта SP" | Obtaining of thromocyte concentrate from plasma enriched with thrombocytes according to "delrus" technology |
-
1922
- 1922-07-22 US US576849A patent/US1599023A/en not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2129883C1 (en) * | 1998-07-08 | 1999-05-10 | Закрытое акционерное общество "Международная компания Дельта SP" | Obtaining of thromocyte concentrate from plasma enriched with thrombocytes according to "delrus" technology |
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