[go: up one dir, main page]

UA99579C2 - АНТИТЕЛО, КОТОРОЕ СВЯЗЫВАЕТСЯ С Tau, ФОСФОРИЛИРОВАННЫМ ПО СЕРИНУ 422 (pS422), ДЛЯ ПРИМЕНЕНИЯ ПРИ ЛЕЧЕНИИ ТАУПАТИИ - Google Patents

АНТИТЕЛО, КОТОРОЕ СВЯЗЫВАЕТСЯ С Tau, ФОСФОРИЛИРОВАННЫМ ПО СЕРИНУ 422 (pS422), ДЛЯ ПРИМЕНЕНИЯ ПРИ ЛЕЧЕНИИ ТАУПАТИИ

Info

Publication number
UA99579C2
UA99579C2 UAA201115476A UAA201115476A UA99579C2 UA 99579 C2 UA99579 C2 UA 99579C2 UA A201115476 A UAA201115476 A UA A201115476A UA A201115476 A UAA201115476 A UA A201115476A UA 99579 C2 UA99579 C2 UA 99579C2
Authority
UA
Ukraine
Prior art keywords
tauopathy
serine
treatment
antibody binding
tau phosphorylated
Prior art date
Application number
UAA201115476A
Other languages
English (en)
Ukrainian (uk)
Inventor
Бернд Борманн
Ульрих ГЁПФЕРТ
Фиона Грюнингер
Вальтер ХУБЕР
Ханс-Вилли КРЕЛЛЬ
Валериа ЛИФКЕ
Олаф МУНДИГЛЬ
Сонья Оффнер
Лоренс ОЗМЕН
Михаель Шремль
Original Assignee
Ф. Хоффманн-Ля Рош Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ф. Хоффманн-Ля Рош Аг filed Critical Ф. Хоффманн-Ля Рош Аг
Publication of UA99579C2 publication Critical patent/UA99579C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Изобретение относится к антителу, которое связывается с Tau, фосфорилированным по серину 422 (ps422), для применения при лечении таупатии, способу продуцирования антитела и фармацевтической композиции, которая его содержит.
UAA201115476A 2009-06-10 2010-06-08 АНТИТЕЛО, КОТОРОЕ СВЯЗЫВАЕТСЯ С Tau, ФОСФОРИЛИРОВАННЫМ ПО СЕРИНУ 422 (pS422), ДЛЯ ПРИМЕНЕНИЯ ПРИ ЛЕЧЕНИИ ТАУПАТИИ UA99579C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP09007656 2009-06-10

Publications (1)

Publication Number Publication Date
UA99579C2 true UA99579C2 (ru) 2012-08-27

Family

ID=40848070

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201115476A UA99579C2 (ru) 2009-06-10 2010-06-08 АНТИТЕЛО, КОТОРОЕ СВЯЗЫВАЕТСЯ С Tau, ФОСФОРИЛИРОВАННЫМ ПО СЕРИНУ 422 (pS422), ДЛЯ ПРИМЕНЕНИЯ ПРИ ЛЕЧЕНИИ ТАУПАТИИ

Country Status (1)

Country Link
UA (1) UA99579C2 (ru)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2661111C2 (ru) * 2013-03-15 2018-07-11 Ац Иммуне С.А. Антитела к тау и способы применения

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2661111C2 (ru) * 2013-03-15 2018-07-11 Ац Иммуне С.А. Антитела к тау и способы применения

Similar Documents

Publication Publication Date Title
PH12013502192A1 (en) Antibodies against human angiopoietin 2
PL2346864T3 (pl) Nowe związki użyteczne do leczenia chorób degeneracyjnych i zapalnych
TW201129381A (en) Antibodies against human CSF-1R and uses thereof
MY161909A (en) Anti-her3 antibodies and uses thereof
TWI449540B (en) Process for the production of an abuse-proofed dosage form
MY147732A (en) Process for the preparation of 2-substituted-5- (1-alkylthio) alkylpyridines
SG10201405377XA (en) Compositions and methods for antibodies targeting complement protein c5
MX2011012837A (es) Uso de un anticuerpo anti-tau ps422 para el tratamiento de enfermedades cerebrales.
TW200716646A (en) (S)-N-methylnaltrexone
PH12013502230A1 (en) Multispecific antibodies
AU2010233994A8 (en) Bispecific anti-ErbB-3/anti-c-Met antibodies
MX2009008430A (es) Anticuerpos anti-robo4 y sus usos.
IL195341A0 (en) Methods and materials for making simvastatin and related compounds
TW201713640A (en) Bruton's tyrosine kinase inhibitors
WO2008046581A3 (de) Substituierte tetrahydropyrrolopyrazin-verbindungen als inhibitoren der monoaminwiederaufnahme und deren verwendung in arzeimitteln
JO3635B1 (ar) مركبات صيدلانية صلبة وطرق لانتاجها
NZ579478A (en) Epha3 antibodies for the treatment of solid tumors
DE602007010764D1 (en) Benzamidglucokinaseaktivatoren
CA2705357C (en) Formulations for taci-immunoglobulin fusion proteins
WO2009150547A3 (en) 2-pyridyl substituted imidazoles as alk4 and/or alk4 inhibitors
WO2008027600A3 (en) Imatinib compositions
JO2682B1 (en) Derivatives of alkynil-8.1-naphthayridone, preparations thereof and therapeutic use thereof
PH12013502194A1 (en) Antibodies to egfl7 and methods for their use
SG143149A1 (en) Phosphite composition and method for producing the same
WO2008075205A3 (en) Improved process for the preparation of voriconazole