[go: up one dir, main page]

UA99510C2 - Комбинация бис-тиазолиевой соли или одного из ее предшественников и артемизинина или одного из его производных для лечения тяжелой формы малярии - Google Patents

Комбинация бис-тиазолиевой соли или одного из ее предшественников и артемизинина или одного из его производных для лечения тяжелой формы малярии

Info

Publication number
UA99510C2
UA99510C2 UAA201010670A UAA201010670A UA99510C2 UA 99510 C2 UA99510 C2 UA 99510C2 UA A201010670 A UAA201010670 A UA A201010670A UA A201010670 A UAA201010670 A UA A201010670A UA 99510 C2 UA99510 C2 UA 99510C2
Authority
UA
Ukraine
Prior art keywords
artemisinin
precursor
bis
derivative
combination
Prior art date
Application number
UAA201010670A
Other languages
English (en)
Ukrainian (uk)
Inventor
Лоран Фресс
Анрі Віаль
Шарон Орор Вейн
Original Assignee
Санофи Авентис
Сантр Насьональ Де Ля Решерш Сьянтифик (Снрс)
Юниверсите Монпелье Ии
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39705083&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA99510(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Санофи Авентис, Сантр Насьональ Де Ля Решерш Сьянтифик (Снрс), Юниверсите Монпелье Ии filed Critical Санофи Авентис
Publication of UA99510C2 publication Critical patent/UA99510C2/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37—Coumarins, e.g. psoralen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Объектом изобретения является комбинация, содержащая бис-тиазолиевую соль (соединение формулы (VI)) или один из ее предшественников и артемизинин или одно из его производных. Объектом изобретения является также фармацевтическая композиция, содержащая по меньшей мере одну бис-тиазолиевую соль (соединение формулы (VI)) или один из ее предшественников и артемизинин или одно из его производных. Кроме того, объектом изобретения является также применение такой комбинации для получения лекарственного средства, предназначенного для лечения или профилактики тяжелой формы малярии. Наконец, объектом изобретения является также набор для лечения или профилактики тяжелой формы малярии.
UAA201010670A 2008-02-06 2009-02-05 Комбинация бис-тиазолиевой соли или одного из ее предшественников и артемизинина или одного из его производных для лечения тяжелой формы малярии UA99510C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0800618A FR2926993B1 (fr) 2008-02-06 2008-02-06 Association entre un sel de bis-thiazolium ou l'un de ses precurseurs et l'artemisinine ou l'un de ses derives pour le traitement du paludisme

Publications (1)

Publication Number Publication Date
UA99510C2 true UA99510C2 (ru) 2012-08-27

Family

ID=39705083

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201010670A UA99510C2 (ru) 2008-02-06 2009-02-05 Комбинация бис-тиазолиевой соли или одного из ее предшественников и артемизинина или одного из его производных для лечения тяжелой формы малярии

Country Status (39)

Country Link
US (1) US8304440B2 (ru)
EP (1) EP2252286B1 (ru)
JP (1) JP5469095B2 (ru)
KR (1) KR20100137442A (ru)
CN (1) CN101980706B (ru)
AP (1) AP2613A (ru)
AR (1) AR070581A1 (ru)
AT (1) ATE521347T1 (ru)
AU (1) AU2009227092B2 (ru)
BR (1) BRPI0907484A2 (ru)
CA (1) CA2714184A1 (ru)
CL (1) CL2009000264A1 (ru)
CO (1) CO6300843A2 (ru)
CR (1) CR11613A (ru)
CY (1) CY1112113T1 (ru)
DK (1) DK2252286T3 (ru)
EA (1) EA022711B1 (ru)
EC (1) ECSP10010381A (ru)
ES (1) ES2372148T3 (ru)
FR (1) FR2926993B1 (ru)
HR (1) HRP20110858T8 (ru)
IL (1) IL207442A0 (ru)
JO (1) JO2820B1 (ru)
MA (1) MA32128B1 (ru)
MX (1) MX2010008653A (ru)
MY (1) MY150776A (ru)
NI (1) NI201000135A (ru)
NZ (1) NZ587232A (ru)
PA (1) PA8815101A1 (ru)
PE (1) PE20091410A1 (ru)
PL (1) PL2252286T3 (ru)
PT (1) PT2252286E (ru)
RS (1) RS52046B (ru)
SI (1) SI2252286T1 (ru)
TW (1) TWI402071B (ru)
UA (1) UA99510C2 (ru)
UY (1) UY31640A1 (ru)
WO (1) WO2009115666A2 (ru)
ZA (1) ZA201005611B (ru)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2951945B1 (fr) * 2009-11-05 2013-08-09 Sanofi Aventis Composition pharmaceutique
AU2014346668C1 (en) 2013-11-08 2018-04-26 Exthera Medical Corporation Methods for diagnosing infectious diseases using adsorption media
US10714230B2 (en) * 2017-12-06 2020-07-14 C3Nano Inc. Thin and uniform silver nanowires, method of synthesis and transparent conductive films formed from the nanowires
CN110604733A (zh) * 2019-09-19 2019-12-24 同济大学 青蒿素类药物与其它药物联用在制备抗疟疾药物中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1058717A (zh) * 1990-08-08 1992-02-19 中国人民解放军军事医学科学院微生物流行病研究所 抗疟新药—复方蒿甲醚及其制备方法
FR2796642B1 (fr) * 1999-07-21 2001-10-19 Centre Nat Rech Scient Precurseurs de sels de bis-ammonium quaternaire et leurs applications comme prodrogues ayant une activite anti-parasitaire
JP2003050535A (ja) * 2001-08-07 2003-02-21 T-Zone Corp ネットワーク教育システム、ネットワーク教育方法、および、プログラム
FR2884715B1 (fr) * 2005-04-20 2007-06-15 Sanofi Aventis Sa Association entre la ferroquine et un derive d'artemisinine pour le traitement du paludisme

Also Published As

Publication number Publication date
CY1112113T1 (el) 2015-11-04
JP2011514319A (ja) 2011-05-06
WO2009115666A3 (fr) 2009-12-23
PE20091410A1 (es) 2009-10-14
HRP20110858T8 (hr) 2012-02-29
HRP20110858T1 (hr) 2012-01-31
PL2252286T3 (pl) 2012-02-29
WO2009115666A2 (fr) 2009-09-24
NI201000135A (es) 2011-04-27
JO2820B1 (en) 2014-09-15
FR2926993B1 (fr) 2011-03-11
TWI402071B (zh) 2013-07-21
NZ587232A (en) 2012-06-29
JP5469095B2 (ja) 2014-04-09
MA32128B1 (fr) 2011-03-01
ZA201005611B (en) 2012-06-27
ECSP10010381A (es) 2010-11-30
EA201070923A1 (ru) 2011-02-28
RS52046B (sr) 2012-04-30
AP2010005353A0 (en) 2010-08-31
MX2010008653A (es) 2011-03-04
EP2252286A2 (fr) 2010-11-24
SI2252286T1 (sl) 2012-01-31
BRPI0907484A2 (pt) 2019-09-24
AR070581A1 (es) 2010-04-21
CN101980706A (zh) 2011-02-23
DK2252286T3 (da) 2011-12-19
AU2009227092A1 (en) 2009-09-24
CO6300843A2 (es) 2011-07-21
HK1152892A1 (en) 2012-03-16
PT2252286E (pt) 2011-12-07
IL207442A0 (en) 2010-12-30
US20110160254A1 (en) 2011-06-30
AP2613A (en) 2013-03-13
KR20100137442A (ko) 2010-12-30
ES2372148T3 (es) 2012-01-16
ATE521347T1 (de) 2011-09-15
CN101980706B (zh) 2013-11-27
CL2009000264A1 (es) 2010-04-09
CR11613A (es) 2010-11-22
FR2926993A1 (fr) 2009-08-07
AU2009227092B2 (en) 2014-08-07
PA8815101A1 (es) 2009-09-17
EA022711B1 (ru) 2016-02-29
US8304440B2 (en) 2012-11-06
UY31640A1 (es) 2009-08-31
CA2714184A1 (fr) 2009-09-24
EP2252286B1 (fr) 2011-08-24
MY150776A (en) 2014-02-28
TW201000098A (en) 2010-01-01

Similar Documents

Publication Publication Date Title
MX2009000884A (es) Derivados de piridizinona.
WO2009152356A3 (en) Compounds and compositions useful for the treatment of malaria
MX2012007375A (es) 3-ceto-n-propargil 1-aminoindano.
WO2009111653A3 (en) Antiviral therapeutic agents
WO2009156462A3 (en) Organic compounds
MX2010009752A (es) Compuestos de oxadiazoantraceno para el tratamiento de diabetes.
TN2012000152A1 (en) Spiropiperidine compounds and pharmaceutical use thereof for treating diabetes
TN2012000248A1 (en) Novel spiropiperidine compounds
TW200801000A (en) Spiroindolinone derivatives
TN2011000291A1 (en) Purine compounds
WO2008083252A3 (en) Methods of use for cyclopamine analogs
MY160392A (en) Triptolide prodrugs
WO2010089327A3 (en) Indole derivatives as anticancer agents
TN2012000105A1 (en) Spirolactam derivatives and uses of same
WO2007131907A3 (en) 1h-indol-5-yl-piperazin-1-yl-methanone derivatives
WO2009145591A3 (en) Phenyl piperazine compounds, pharmaceutical composition including the same, and use thereof
MY150776A (en) Combination of a bis-thiazolium salt or a precursor thereof and artemisinin or a derivative thereof for treating acute malaria
WO2007066337A3 (en) Jasmonate derivatives, pharmaceutical compositions and methods of use thereof
TW200800993A (en) Organic compounds
WO2008098143A3 (en) Antimicrobial compounds and methods of use
WO2009124723A9 (en) Novel aureothin derivatives
TNSN08242A1 (en) 2-carbamide-4-phenylthiazole derivatives, preparation thereof and therapeutic use thereof
TN2010000353A1 (en) Combination of a bis-thiazolium salt or a precursor thereof and artemisinin or a derivative thereof for treating acute malaria
JO2979B1 (en) Cyclopropyl compounds
UA106223C2 (en) Sulfamoyl-phenyl-ureido benzamidine-derivatives as antimalarial agents