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UA98153C2 - Цитотоксичний засіб, що включає похідні томайміцину, і його терапевтичне застосування - Google Patents

Цитотоксичний засіб, що включає похідні томайміцину, і його терапевтичне застосування

Info

Publication number
UA98153C2
UA98153C2 UAA201001752A UAA201001752A UA98153C2 UA 98153 C2 UA98153 C2 UA 98153C2 UA A201001752 A UAA201001752 A UA A201001752A UA A201001752 A UAA201001752 A UA A201001752A UA 98153 C2 UA98153 C2 UA 98153C2
Authority
UA
Ukraine
Prior art keywords
cytotoxic agent
therapeutic use
tomaymycin derivatives
relates
derivatives
Prior art date
Application number
UAA201001752A
Other languages
English (en)
Russian (ru)
Inventor
Ерве Бушар
Раві В. Дж. Чарі
Алєн Коммерсон
Юнхун Ден
Лоранс Гозі
Original Assignee
Санофі-Авентіс
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39048765&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA98153(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Санофі-Авентіс filed Critical Санофі-Авентіс
Publication of UA98153C2 publication Critical patent/UA98153C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Винахід стосується нових похідних томайміцину, що містять лінкер. Винахід також стосується кон'югатних молекул, які містять одне або більше зазначених похідних томайміцину, ковалентно зв'язаних з агентом, що зв'язується із клітиною, за допомогою зшивальної групи, присутньої на лінкері похідної сполуки томайміцину. Винахід також стосується одержання похідних сполук томайміцину й кон'югатних молекул.
UAA201001752A 2007-07-19 2008-07-18 Цитотоксичний засіб, що включає похідні томайміцину, і його терапевтичне застосування UA98153C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07290904.7A EP2019104B1 (en) 2007-07-19 2007-07-19 Cytotoxic agents comprising new tomaymycin derivatives and their therapeutic use
PCT/IB2008/002869 WO2009016516A2 (en) 2007-07-19 2008-07-18 Cytotoxic agents comprising new tomaymycin derivatives and their therapeutic use

Publications (1)

Publication Number Publication Date
UA98153C2 true UA98153C2 (uk) 2012-04-25

Family

ID=39048765

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201001752A UA98153C2 (uk) 2007-07-19 2008-07-18 Цитотоксичний засіб, що включає похідні томайміцину, і його терапевтичне застосування

Country Status (39)

Country Link
US (1) US8404678B2 (uk)
EP (2) EP2019104B1 (uk)
JP (1) JP5551070B2 (uk)
KR (1) KR101627871B1 (uk)
CN (1) CN101784550B (uk)
AR (1) AR067575A1 (uk)
AT (1) ATE530553T1 (uk)
AU (1) AU2008281439B2 (uk)
BR (1) BRPI0814267A2 (uk)
CA (1) CA2693551C (uk)
CL (1) CL2008002139A1 (uk)
CO (1) CO6290692A2 (uk)
CR (1) CR11225A (uk)
CY (2) CY1112278T1 (uk)
DK (2) DK2019104T3 (uk)
DO (1) DOP2010000014A (uk)
EA (1) EA019938B1 (uk)
EC (1) ECSP109875A (uk)
ES (2) ES2435779T3 (uk)
GT (1) GT201000008A (uk)
HR (1) HRP20120067T1 (uk)
IL (1) IL203318A (uk)
JO (1) JO2744B1 (uk)
MA (1) MA31617B1 (uk)
ME (1) ME00969B (uk)
MY (1) MY151245A (uk)
NI (1) NI201000005A (uk)
NZ (1) NZ582679A (uk)
PA (1) PA8790201A1 (uk)
PE (2) PE20130590A1 (uk)
PL (2) PL2019104T3 (uk)
PT (2) PT2019104E (uk)
RS (1) RS52245B (uk)
SI (2) SI2019104T1 (uk)
TN (1) TN2010000002A1 (uk)
TW (1) TWI500618B (uk)
UA (1) UA98153C2 (uk)
WO (1) WO2009016516A2 (uk)
ZA (1) ZA201000389B (uk)

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