UA92047C2 - Carbonylamino pyrrolopyrazoles, potent kinase inhibitors - Google Patents
Carbonylamino pyrrolopyrazoles, potent kinase inhibitorsInfo
- Publication number
- UA92047C2 UA92047C2 UAA200807387A UAA200807387A UA92047C2 UA 92047 C2 UA92047 C2 UA 92047C2 UA A200807387 A UAA200807387 A UA A200807387A UA A200807387 A UAA200807387 A UA A200807387A UA 92047 C2 UA92047 C2 UA 92047C2
- Authority
- UA
- Ukraine
- Prior art keywords
- kinase inhibitors
- pyrrolopyrazoles
- carbonylamino
- potent kinase
- compounds
- Prior art date
Links
- XPBFIMLMVNXIIB-UHFFFAOYSA-N 3-isocyanatopyrrolo[3,2-c]pyrazole Chemical class N1=CC=C2N=NC(N=C=O)=C21 XPBFIMLMVNXIIB-UHFFFAOYSA-N 0.000 title 1
- 229940043355 kinase inhibitor Drugs 0.000 title 1
- 239000003757 phosphotransferase inhibitor Substances 0.000 title 1
- 230000003389 potentiating effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 101000987297 Homo sapiens Serine/threonine-protein kinase PAK 4 Proteins 0.000 abstract 1
- 102100027940 Serine/threonine-protein kinase PAK 4 Human genes 0.000 abstract 1
- 229940045988 antineoplastic drug protein kinase inhibitors Drugs 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000003909 protein kinase inhibitor Substances 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Carbonyiamino Pyirolopyrazole compounds of formula (I), compositions including these compounds and methods of their use are provided. Preferred compounds of formula (I) have activity as protein kinase inhibitors, including as inhibitors of PAK4. EMBED ISISServer I
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75334905P | 2005-12-21 | 2005-12-21 | |
| US86493206P | 2006-11-08 | 2006-11-08 | |
| PCT/IB2006/003646 WO2007072153A2 (en) | 2005-12-21 | 2006-12-12 | Carbonylamino pyrrolopyrazoles, potent kinase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA92047C2 true UA92047C2 (en) | 2010-09-27 |
Family
ID=40247953
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200807387A UA92047C2 (en) | 2005-12-21 | 2006-12-12 | Carbonylamino pyrrolopyrazoles, potent kinase inhibitors |
Country Status (5)
| Country | Link |
|---|---|
| CN (1) | CN101346382B (en) |
| SI (1) | SI1979356T1 (en) |
| TN (1) | TNSN08274A1 (en) |
| UA (1) | UA92047C2 (en) |
| ZA (1) | ZA200804667B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113234081A (en) * | 2021-05-27 | 2021-08-10 | 东南大学 | Preparation method of pyrrolopyrazole derivative and DMDPEDA as urea |
| CN117185993B (en) * | 2023-08-28 | 2025-08-12 | 南通华祥医药科技有限公司 | Preparation and application of an amide compound containing a substituted phenylthiopyridine structural unit |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA81790C2 (en) * | 2002-12-19 | 2008-02-11 | Фармация Италия С.П.А. | Substituted derivatives of pyrolopyrazol as kinaze inhibitors |
-
2006
- 2006-12-12 SI SI200631657T patent/SI1979356T1/en unknown
- 2006-12-12 UA UAA200807387A patent/UA92047C2/en unknown
- 2006-12-12 CN CN2006800486846A patent/CN101346382B/en not_active Expired - Fee Related
-
2008
- 2008-05-29 ZA ZA200804667A patent/ZA200804667B/en unknown
- 2008-06-20 TN TNP2008000274A patent/TNSN08274A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TNSN08274A1 (en) | 2009-10-30 |
| CN101346382A (en) | 2009-01-14 |
| SI1979356T1 (en) | 2013-11-29 |
| CN101346382B (en) | 2011-07-06 |
| ZA200804667B (en) | 2010-05-26 |
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