[go: up one dir, main page]

UA92752C2 - Способ получения кристаллического периндоприла - Google Patents

Способ получения кристаллического периндоприла

Info

Publication number
UA92752C2
UA92752C2 UAA200801935A UAA200801935A UA92752C2 UA 92752 C2 UA92752 C2 UA 92752C2 UA A200801935 A UAA200801935 A UA A200801935A UA A200801935 A UAA200801935 A UA A200801935A UA 92752 C2 UA92752 C2 UA 92752C2
Authority
UA
Ukraine
Prior art keywords
preparation
perindopril
crystalline perindopril
crystalline
relates
Prior art date
Application number
UAA200801935A
Other languages
English (en)
Ukrainian (uk)
Inventor
Бранко Энко
Антон Копар
Original Assignee
Лек Фармасьютикалз Д.Д.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Лек Фармасьютикалз Д.Д. filed Critical Лек Фармасьютикалз Д.Д.
Publication of UA92752C2 publication Critical patent/UA92752C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Данное изобретение относится к новому способу получения кристаллического периндоприла. Данное изобретение также относится к новым солям алкиламония и периндоприла и способов их получения.
UAA200801935A 2005-07-25 2006-07-24 Способ получения кристаллического периндоприла UA92752C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SI200500214 2005-07-25

Publications (1)

Publication Number Publication Date
UA92752C2 true UA92752C2 (ru) 2010-12-10

Family

ID=37451139

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200801935A UA92752C2 (ru) 2005-07-25 2006-07-24 Способ получения кристаллического периндоприла

Country Status (14)

Country Link
US (1) US7923570B2 (ru)
EP (1) EP1910287B1 (ru)
JP (1) JP4972643B2 (ru)
CN (1) CN101228126B (ru)
AT (1) ATE549315T1 (ru)
AU (1) AU2006278866B2 (ru)
BR (1) BRPI0613976A2 (ru)
CA (1) CA2615691C (ru)
EA (1) EA013018B1 (ru)
MX (1) MX2008001151A (ru)
SI (1) SI1910287T1 (ru)
UA (1) UA92752C2 (ru)
WO (1) WO2007017087A1 (ru)
ZA (1) ZA200800138B (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2618561C (en) * 2005-08-12 2014-04-29 Lek Pharmaceuticals D.D. A process for the preparation of perindopril erbumine
AU2006281681A1 (en) * 2005-08-12 2007-02-22 Sandoz Ag New crystalline form of perindopril erbumine
SI22543A (sl) * 2007-06-27 2008-12-31 Krka, Tovarna Zdravil, D.D., Novo Mesto Nove soli perindoprila
GB0910692D0 (en) 2009-06-20 2009-08-05 Teva Pharma Compound
CN111116709B (zh) * 2019-12-31 2022-06-24 北京鑫开元医药科技有限公司 一种培哚普利制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2620709B1 (fr) * 1987-09-17 1990-09-07 Adir Procede de synthese industrielle du perindopril et de ses principaux intermediaires de synthese
US20020107230A1 (en) * 2000-12-22 2002-08-08 Waldon R. Forrest Methods and formulations for the treatment of female sexual dysfunction
GB2395195A (en) * 2002-11-18 2004-05-19 Cipla Ltd Preparation of perindopril from carboxy-protected precursor, & perindopril monohydrates for use as angiotensin converting enzyme (ACE) inhibitors
AU2003263584A1 (en) 2003-08-21 2005-03-10 Hetero Drugs Limited Process for pure perindopril tert-butylamine salt
SI21704A (en) 2004-01-14 2005-08-31 Lek Farmacevtska Druzba Dd New crystal form of perindopril, procedure of its preparation, pharmaceutical preparations containing this form and their application in treatment of hypertensia

Also Published As

Publication number Publication date
EA200800200A1 (ru) 2008-06-30
WO2007017087A1 (en) 2007-02-15
JP4972643B2 (ja) 2012-07-11
EP1910287B1 (en) 2012-03-14
MX2008001151A (es) 2008-03-13
AU2006278866A1 (en) 2007-02-15
CA2615691A1 (en) 2007-02-15
BRPI0613976A2 (pt) 2011-02-22
JP2009502833A (ja) 2009-01-29
ZA200800138B (en) 2009-08-26
US20080306135A1 (en) 2008-12-11
ATE549315T1 (de) 2012-03-15
US7923570B2 (en) 2011-04-12
EA013018B1 (ru) 2010-02-26
EP1910287A1 (en) 2008-04-16
CN101228126B (zh) 2011-10-19
CA2615691C (en) 2015-11-10
CN101228126A (zh) 2008-07-23
SI1910287T1 (sl) 2012-09-28
AU2006278866B2 (en) 2012-03-15

Similar Documents

Publication Publication Date Title
MX2010002836A (es) Bortezomib y proceso para la produccion del mismo.
MY148253A (en) Azaadamantane derivatives and methods of use
TW200716512A (en) Processes for preparing cinacalcet hydrochloride crystal form I
MY147732A (en) Process for the preparation of 2-substituted-5- (1-alkylthio) alkylpyridines
MX2009003257A (es) Procedimiento para la sintesis de derivados de fenoxi diaminopirimidina.
PH12013502448A1 (en) Processes and intermediates for making sweet taste enhancers
TW200420541A (en) Crystalline forms
MY146084A (en) Benzyl amines, a process for their production and their use as anti-inflammatory agents
WO2008053334A3 (en) An improved process for preparing rosuvastatin calcium
TNSN08244A1 (en) Process for the preparation of ferri-succinylcasein
WO2006113509A3 (en) Quinobenzoxazine analogs and methods of using thereof
MXPA05013751A (es) Procedimiento e intermediarios para la preparacion de 3-(amino)-3-ciclobutilmetil-2-hidroxi-propionamida o sus sales.
ZA200800138B (en) Process for the preparation of crystalline perindopril
TW200720366A (en) Process for preparing metal compounds of an azo compound in the presence of seed crystals
IL183271A0 (en) Crystalline form of cefdinir ammonium salt as an intermediate for the preparation of pure cefdinir
UA102816C2 (ru) Способ синтеза кристаллической формы v агомелатина
TW200612959A (en) Method for preparing hydroxamic acids
WO2009122429A3 (en) Crystalline oxybutynin and process for preparing the same
EA200870038A1 (ru) Способ получения аминов
TW200637832A (en) Process for preparing amorphous valsartan
TW200635905A (en) Processes for producing 4-aminoquinazolines
TW200730521A (en) Triazine compounds having amino-and carboxyl-containing substituents
TW200719889A (en) Amino acid derivatives
UA91733C2 (ru) Способ получения кристаллической формы орлистата
MX2008002066A (es) Neuva forma cristalina de perindopril-erbumina.