[go: up one dir, main page]

UA91673C2 - Сложные эфиры гиалуроновой кислоты с реином, способ их получения и композиция, которая содержит эти эфиры - Google Patents

Сложные эфиры гиалуроновой кислоты с реином, способ их получения и композиция, которая содержит эти эфиры

Info

Publication number
UA91673C2
UA91673C2 UAA200609263A UAA200609263A UA91673C2 UA 91673 C2 UA91673 C2 UA 91673C2 UA A200609263 A UAA200609263 A UA A200609263A UA A200609263 A UAA200609263 A UA A200609263A UA 91673 C2 UA91673 C2 UA 91673C2
Authority
UA
Ukraine
Prior art keywords
rhein
hyaluronic acid
esters
compositions
preparation
Prior art date
Application number
UAA200609263A
Other languages
English (en)
Ukrainian (uk)
Inventor
Антонелло П'єтранджело
Вальтер Травальі
Original Assignee
Лаборатори Медидом С.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Лаборатори Медидом С.А. filed Critical Лаборатори Медидом С.А.
Publication of UA91673C2 publication Critical patent/UA91673C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)

Abstract

Это изобретение касается сложных эфиров гиалуроновой кислоты с реином, более конкретно, соединения на основе гиалуроновой кислоты, где спиртовые группы гиалуроновой кислоты эстерифицированы реином, способа получения упомянутого сложного эфира и фармацевтической композиции, которая содержит упомянутый сложный эфир.
UAA200609263A 2004-02-26 2005-02-25 Сложные эфиры гиалуроновой кислоты с реином, способ их получения и композиция, которая содержит эти эфиры UA91673C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000347A ITMI20040347A1 (it) 2004-02-26 2004-02-26 Nuovo farmaco di associazione
PCT/IB2005/000506 WO2005085293A1 (en) 2004-02-26 2005-02-25 Esters of hyaluronic acid with rhein, process for their preparation and compositions comprising the same

Publications (1)

Publication Number Publication Date
UA91673C2 true UA91673C2 (ru) 2010-08-25

Family

ID=34917538

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200609263A UA91673C2 (ru) 2004-02-26 2005-02-25 Сложные эфиры гиалуроновой кислоты с реином, способ их получения и композиция, которая содержит эти эфиры

Country Status (17)

Country Link
US (1) US7834173B2 (ru)
EP (1) EP1718679B1 (ru)
JP (2) JP4870068B2 (ru)
CN (1) CN100551932C (ru)
AT (1) ATE373681T1 (ru)
BR (1) BRPI0507622B8 (ru)
CA (1) CA2556942C (ru)
DE (1) DE602005002538T2 (ru)
ES (1) ES2293538T3 (ru)
IL (1) IL177072A (ru)
IT (1) ITMI20040347A1 (ru)
PL (1) PL1718679T3 (ru)
PT (1) PT1718679E (ru)
RU (1) RU2383554C2 (ru)
SI (1) SI1718679T1 (ru)
UA (1) UA91673C2 (ru)
WO (1) WO2005085293A1 (ru)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE20060049A1 (en) * 2006-01-25 2007-08-08 Eurand Pharmaceuticals Ltd A novel drug delivery system: use of hyaluronic acid as a carrier moleclue for different classes of therapeutic active agents
ITMI20062134A1 (it) * 2006-11-08 2008-05-09 Cbb Net S A Preparaziobne di esteri della diacereina con acido ialuronico e loro formulazioni per l'impiego farmaceutico
EP2097116B1 (en) * 2006-12-22 2012-09-12 Laboratoire Medidom S.A. In situ system for intra-articular chondral and osseous tissue repair
ITMI20072237A1 (it) * 2007-11-27 2009-05-28 Sigea Srl Esteri misti butirrico-formico di polisaccaridi acidi, loro preparazione ed uso come dermocosmetici
WO2009133430A1 (en) * 2008-04-30 2009-11-05 Wockhardt Research Centre Topical compositions of rhein or diacerein
US8722644B2 (en) 2010-01-04 2014-05-13 Holy Stone Healthcare Co., Ltd. Mixture of hyaluronic acid for treating and preventing peptic ulcer and duodenal ulcer
WO2012013670A1 (en) 2010-07-29 2012-02-02 University Of Geneva Process for the esterification of hyaluronic acid with hydrophobic organic compounds
CN102603575B (zh) * 2012-01-04 2014-08-13 丛晓东 大精酸共晶物、其制备方法、纯化方法及其在制备治疗糖尿病并发症药物中的应用
GB2501943B (en) * 2012-05-10 2020-09-23 Zeiss Carl Meditec Ag Ophthalmic viscoelastic device
RU2534789C1 (ru) * 2013-06-19 2014-12-10 Сергей Алексеевич Успенский Твердофазный способ получения водорастворимого биоактивного нанокомпозита на основе модифицированной лимонной кислотой гиалуроновой кислоты и наночастиц золота
KR101486147B1 (ko) * 2013-07-09 2015-01-23 주식회사 엘지생활건강 Tslp 분비 저해능 및 이에 의한 알러지성 질환의 개선능을 가지는 조성물
MA41912A (fr) * 2015-04-07 2018-02-13 Hyalblue S R L Esters de glycosaminoglycane, procédés pour leur préparation et leur utilisation dans des formulations à usage ophtalmique
EP3813895B1 (en) * 2018-06-29 2025-07-30 Merz Pharma GmbH & Co. KGaA Fatty acid-grafted hyaluronic acid, dermal filler formulations comprising same, process for preparation and use thereof
CN109833292A (zh) * 2019-02-23 2019-06-04 河南省人民医院 一种双醋瑞因滴眼液及其用途
CN112138169A (zh) * 2020-09-14 2020-12-29 广东药科大学 天然多糖在增加难溶性药物溶解度中的应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4788187A (en) * 1983-04-29 1988-11-29 Rorer Pharmaceutical Corporation Benzocyclobutene aminoalkylene ethers and thioethers, pharmaceutical composition and use
DE4120990C2 (de) * 1991-06-25 1995-07-27 Madaus Ag Verfahren zur Herstellung von Diacetylrhein
US5573934A (en) * 1992-04-20 1996-11-12 Board Of Regents, The University Of Texas System Gels for encapsulation of biological materials
NZ245989A (en) * 1992-02-28 1995-02-24 Lilly Industries Ltd Anthraquinone derivatives and pharmaceutical compositions
ZA936692B (en) * 1992-09-12 1994-04-29 Dott Ltd Comp Physiologically active peptide composition
CA2094203A1 (en) * 1993-04-16 1994-10-17 Derek A. Willoughby Inhibition of angiogenesis
US5612321A (en) * 1995-06-22 1997-03-18 Hercules Incorporated Antioxidant grafted polysaccharides
FR2751615B1 (fr) * 1996-07-23 1998-09-18 Otor Sa Plateau et flan en matiere en feuille de carton
JP3322203B2 (ja) * 1997-01-31 2002-09-09 田辺製薬株式会社 医薬組成物
EP1082963A4 (en) * 1998-05-20 2004-03-17 Chugai Pharmaceutical Co Ltd MEDICINE FOR HYALURONIC ACID-ASSOCIATED JOINT DISEASES
ITMI20022745A1 (it) * 2002-12-23 2004-06-24 Coimex Scrl United Companies Esteri misti dell'acido ialuronico ad attivita' citostatica e prodifferenziante e procedimento per la loro produzione.

Also Published As

Publication number Publication date
EP1718679B1 (en) 2007-09-19
ES2293538T3 (es) 2008-03-16
JP4870068B2 (ja) 2012-02-08
CA2556942C (en) 2012-05-29
ITMI20040347A1 (it) 2004-05-26
HK1099032A1 (zh) 2007-08-03
PT1718679E (pt) 2007-11-27
CA2556942A1 (en) 2005-09-15
ATE373681T1 (de) 2007-10-15
SI1718679T1 (sl) 2008-02-29
BRPI0507622A (pt) 2007-07-03
IL177072A (en) 2011-02-28
BRPI0507622B8 (pt) 2021-05-25
EP1718679A1 (en) 2006-11-08
JP2011252153A (ja) 2011-12-15
DE602005002538T2 (de) 2008-06-19
DE602005002538D1 (de) 2007-10-31
JP2007524753A (ja) 2007-08-30
PL1718679T3 (pl) 2008-01-31
RU2383554C2 (ru) 2010-03-10
CN100551932C (zh) 2009-10-21
CN1914228A (zh) 2007-02-14
WO2005085293A1 (en) 2005-09-15
US7834173B2 (en) 2010-11-16
BRPI0507622B1 (pt) 2018-07-17
IL177072A0 (en) 2006-12-10
RU2006134015A (ru) 2008-04-10
US20070203094A1 (en) 2007-08-30

Similar Documents

Publication Publication Date Title
PL1718679T3 (pl) Estry kwasu hialuronowego z reiną, sposób otrzymywania oraz kompozycje je zawierające
NZ597193A (en) Compositions and methods for lowering triglycerides without raising ldl-c levels in a subject on concomitant statin therapy
EP2011545A3 (en) Structured compositions comprising betaine
EP2588518A4 (en) Cellulosic and cellulosic esters / elastomers compositions and method of preparation therefor
BRPI1014472A8 (pt) Método para produzir um derivado de ácido graxo, microrganismo engenheirado geneticamente, derivado de ácido graxo e composição de biocombustível
EP4556073A3 (en) Eicosapentaenoic acid ethyl ester for use in reducing the risk of non-fatal myocardial infarction in a subject on statin therapy
NZ708558A (en) Preparation of poly alpha-1,3-glucan esters and films therefrom
WO2009150023A3 (de) Verfähren zur herstellung von sphingolipiden durch enzymatische n-acylierung von lysosphingolipiden unter verwendung einer lipase und eines fettsäureglycerinesters
EP2194119A3 (en) Production of fatty acids and derivatives thereof
EP3623465A3 (en) Production of fatty acids and derivatives thereof
WO2005103253A8 (en) Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
WO2009150022A3 (de) Verfahren zur herstellung von sphingolipiden durch enzymatische n-acylierung von lysosphingolipiden unter verwendung einer pilz-lipase und eines fettsäurealkylesters
WO2008063300A8 (en) Boronic acids and esters as inhibitors of fatty acid amide hydrolase
UA102574C2 (ru) 1-фенил-2-пиридинилалкил-спиртовые производные как ингибиторы фосфодиэстеразы
WO2011103151A3 (en) Oil compositions of stearidonic acid
SG10201805198TA (en) 18f - fluciclovine compositions in citrate buffers
WO2009095197A3 (de) Zusammensetzungen enthaltend phosphorsäureester und hydrophob modifizierte, vernetzte, anionische polymere
WO2011103193A3 (en) COPOLYESTERS HAVING REPEAT UNITS DERIVED FROM ω-HYDROXY FATTY ACIDS
WO2010108060A8 (en) Fatty acid monoglyceride compositions
MY182542A (en) Methods of refining and producing dibasic esters and acids from natural oil feedstocks
MX2009001404A (es) Esteres de nitrato de piperidinas.
BR0109586A (pt) Composições contendo policarbonato
IN2014DN03355A (ru)
NZ599268A (en) Pharmaceutical compositions of rhein or diacerein made by wet granulation process
WO2011043806A3 (en) Compositions and methods for promoting fatty acid production in plants