UA90346C2 - Orally absorbed pharmaceutical formulation and method of administration - Google Patents
Orally absorbed pharmaceutical formulation and method of administrationInfo
- Publication number
- UA90346C2 UA90346C2 UAA200804942A UAA200804942A UA90346C2 UA 90346 C2 UA90346 C2 UA 90346C2 UA A200804942 A UAA200804942 A UA A200804942A UA A200804942 A UAA200804942 A UA A200804942A UA 90346 C2 UA90346 C2 UA 90346C2
- Authority
- UA
- Ukraine
- Prior art keywords
- pharmaceutical formulation
- formulation
- administration
- aerosol
- metered dose
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 4
- -1 alkali metal alkyl sulfate Chemical class 0.000 abstract 3
- 102000004877 Insulin Human genes 0.000 abstract 2
- 108090001061 Insulin Proteins 0.000 abstract 2
- 239000000443 aerosol Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- 229940125396 insulin Drugs 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 229920003171 Poly (ethylene oxide) Polymers 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 229920001400 block copolymer Polymers 0.000 abstract 1
- 235000012054 meals Nutrition 0.000 abstract 1
- 239000008177 pharmaceutical agent Substances 0.000 abstract 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 abstract 1
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 abstract 1
- 229920001451 polypropylene glycol Polymers 0.000 abstract 1
- 229920000053 polysorbate 80 Polymers 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
A pharmaceutical formulation for absorption through oral mucosae comprising an effective amount of (a) a pharmaceutical agent in mixed micellar form, (b) at least one micelle-forming compound selected from the group comprising an alkali metal alkyl sulfate and a polyoxyethylene sorbitan monooleate, (c) a block copolymer of polyoxyethylene and polyoxypropylene, (d) at least one additional micelle-forming compound, and (e) a suitable solvent. The invention also provides a metered dose dispenser (aerosol or non-aerosol) containing the present formulation and a method of administering insulin using the metered dose dispenser comprising administering split doses of a formulation containing insulin before and after each meal.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| UAA200804942A UA90346C2 (en) | 2005-11-30 | 2005-11-30 | Orally absorbed pharmaceutical formulation and method of administration |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| UAA200804942A UA90346C2 (en) | 2005-11-30 | 2005-11-30 | Orally absorbed pharmaceutical formulation and method of administration |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA90346C2 true UA90346C2 (en) | 2010-04-26 |
Family
ID=50689754
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200804942A UA90346C2 (en) | 2005-11-30 | 2005-11-30 | Orally absorbed pharmaceutical formulation and method of administration |
Country Status (1)
| Country | Link |
|---|---|
| UA (1) | UA90346C2 (en) |
-
2005
- 2005-11-30 UA UAA200804942A patent/UA90346C2/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ECSP088403A (en) | PHARMACEUTICAL FORMULATION OF ORAL ABSORPTION AND ITS METHOD OF ADMINISTRATION | |
| DK1257254T3 (en) | Formulations containing an anticholinergic drug for the treatment of chronic obstructive pulmonary disease | |
| WO2005041925A3 (en) | Compositions and dosage forms for enhanced absorption | |
| BG105033A (en) | PHARMACEUTICAL COMPOSITIONS FOR AEROSOLS WITH TWO OR MORE ACTIVE SUBSTANCES | |
| WO2004054542A3 (en) | Oral drug delivery system comprising high viscosity liquid carrier materials | |
| TN2009000504A1 (en) | Pharmaceutical formulation in mixed micellar form and dispenser for oral delivery of agents as a spray | |
| NO20061925L (en) | Pharmaceutical preparations for the prevention of overdose or abuse | |
| TW200500098A (en) | Methods and dosage forms for increasing solubility of drug compositions for controlled delivery | |
| IL165601A0 (en) | Oral pharmaceutical forms of liquid drugs having improved bioavailability | |
| ES2184310T3 (en) | SELF-EMULSIONING FORMULATION FOR LIPOFIL ACID COMPOUNDS | |
| AR034813A1 (en) | PHARMACEUTICAL COMPOSITIONS AND USE OF THE SAME | |
| WO2005097076A3 (en) | Low dose pharmaceutical products | |
| TNSN01003A1 (en) | APPARATUS FOR DELIVERY OF DOSE COUNTING AEROSOLS IN HYDROFLUOROALKAN PROPELLERS. | |
| TNSN07289A1 (en) | Pharmaceutical aerosol formulations for pressurized metered dose inhalers comprising a sequestering agent | |
| NO20083759L (en) | Dosage aerosols for administration of pharmaceutical compositions | |
| WO2005065639A3 (en) | Novel pharmaceutical compositions | |
| WO2008079343A3 (en) | Composition of and method for preparing orally disintegrating tablets containing a high dose of pharmaceutically active ingredients | |
| WO2007047371A3 (en) | Pharmaceutical packaging of an oral dosage combination | |
| WO2007020204A3 (en) | Hfc solution formulations for inhalation containing salbutamol hydrochloride or salbutamol citrate | |
| UA90346C2 (en) | Orally absorbed pharmaceutical formulation and method of administration | |
| WO2005004878A3 (en) | Multi-use vessels for vitamin d formulations, preferably administeredat high dose and periodically | |
| CR9941A (en) | PHARMACEUTICAL TRAINING OF ORAL ABSORPTION AND ITS METHOD OF ADMINISTRATION | |
| MX2007003468A (en) | Medicinal aerosol formulations and methods of synthesizing ingredients therefor. | |
| WO2002041875A3 (en) | Method for producing readily soluble medicament formulations and corresponding formulations | |
| MA30067B1 (en) | ORALLY ABSORBED PHARMACEUTICAL FORMULATION AND METHOD OF ADMINISTRATION |