UA90706U - Method for medicamentous correction of the impaired production of nitric oxide in treating diabetic nephropathy - Google Patents
Method for medicamentous correction of the impaired production of nitric oxide in treating diabetic nephropathyInfo
- Publication number
- UA90706U UA90706U UAU201314642U UAU201314642U UA90706U UA 90706 U UA90706 U UA 90706U UA U201314642 U UAU201314642 U UA U201314642U UA U201314642 U UAU201314642 U UA U201314642U UA 90706 U UA90706 U UA 90706U
- Authority
- UA
- Ukraine
- Prior art keywords
- nitric oxide
- diabetic nephropathy
- medicamentous
- correction
- treating diabetic
- Prior art date
Links
- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 title abstract 6
- 208000007342 Diabetic Nephropathies Diseases 0.000 title abstract 3
- 208000033679 diabetic kidney disease Diseases 0.000 title abstract 3
- 230000001771 impaired effect Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 102100029438 Nitric oxide synthase, inducible Human genes 0.000 abstract 2
- 101710089543 Nitric oxide synthase, inducible Proteins 0.000 abstract 2
- 238000002648 combination therapy Methods 0.000 abstract 2
- 230000003511 endothelial effect Effects 0.000 abstract 2
- ODKSFYDXXFIFQN-BYPYZUCNSA-N L-arginine Chemical compound OC(=O)[C@@H](N)CCCN=C(N)N ODKSFYDXXFIFQN-BYPYZUCNSA-N 0.000 abstract 1
- 229930064664 L-arginine Natural products 0.000 abstract 1
- 235000014852 L-arginine Nutrition 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 210000000265 leukocyte Anatomy 0.000 abstract 1
- 230000001607 nephroprotective effect Effects 0.000 abstract 1
- 210000005259 peripheral blood Anatomy 0.000 abstract 1
- 239000011886 peripheral blood Substances 0.000 abstract 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The method for treating the diabetic nephropathy comprises the basic combined therapy using blood sugar-lowering and nephroprotective drugs. Prior to the treatment, immunocytochemical examination of the leukocytes from the peripheral blood is provided. The functional state of the system of nitric oxide production is assessed as the additional factor of the development and progression of the diabetic nephropathy. Ratio of endothelial to inducible NO-synthase expression is calculated. If K is less than 1, the impaired production of nitric oxide is suggested manifesting as the disbalance between endothelial and inducible NO-synthase. In such cases, the donator of L-arginine is provided as the additional nephroproptector in the setting of the basic combined therapy.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| UAU201314642U UA90706U (en) | 2013-12-13 | 2013-12-13 | Method for medicamentous correction of the impaired production of nitric oxide in treating diabetic nephropathy |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| UAU201314642U UA90706U (en) | 2013-12-13 | 2013-12-13 | Method for medicamentous correction of the impaired production of nitric oxide in treating diabetic nephropathy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA90706U true UA90706U (en) | 2014-06-10 |
Family
ID=56283449
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAU201314642U UA90706U (en) | 2013-12-13 | 2013-12-13 | Method for medicamentous correction of the impaired production of nitric oxide in treating diabetic nephropathy |
Country Status (1)
| Country | Link |
|---|---|
| UA (1) | UA90706U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2691641C2 (en) * | 2016-05-17 | 2019-06-17 | Гульнара Султановна Шаманова | Method of treatment of diabetes mellitus of the second type and its dermal complications |
-
2013
- 2013-12-13 UA UAU201314642U patent/UA90706U/en unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2691641C2 (en) * | 2016-05-17 | 2019-06-17 | Гульнара Султановна Шаманова | Method of treatment of diabetes mellitus of the second type and its dermal complications |
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