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UA89617C2 - Succinate and malonate salt of trans 4-(1r,3s)-6-chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and use thereof as a medicament - Google Patents

Succinate and malonate salt of trans 4-(1r,3s)-6-chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and use thereof as a medicament

Info

Publication number
UA89617C2
UA89617C2 UAA200602709A UAA200602709A UA89617C2 UA 89617 C2 UA89617 C2 UA 89617C2 UA A200602709 A UAA200602709 A UA A200602709A UA A200602709 A UAA200602709 A UA A200602709A UA 89617 C2 UA89617 C2 UA 89617C2
Authority
UA
Ukraine
Prior art keywords
phenylindan
trimethylpiperazine
chloro
succinate
trans
Prior art date
Application number
UAA200602709A
Other languages
Russian (ru)
Inventor
Де Диего Хейди Лопес
Оле Нильсен
Лоне Мунк Рингор
Хенрик Сван
Аллан Карстен Дахл
Марк Хауелз
Бенни Банг-Андерсен
Ларс Оле Лингсьо
Шерри Линн Коллиэр
Original Assignee
Х. Луннбек А/С
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Х. Луннбек А/С filed Critical Х. Луннбек А/С
Publication of UA89617C2 publication Critical patent/UA89617C2/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

4-((1R,3S)-6-Chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine hydrogen succinate or hydrogen malonat, pharmaceutical compositions containing these salts and the medical use thereof, including for the treatment of schizophrenia and other psychotic disorders. Also described are methods for the preparation of 4-((1R,3S)-6-chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and medical uses thereof.
UAA200602709A 2003-08-18 2004-08-18 Succinate and malonate salt of trans 4-(1r,3s)-6-chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and use thereof as a medicament UA89617C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200301180 2003-08-18

Publications (1)

Publication Number Publication Date
UA89617C2 true UA89617C2 (en) 2010-02-25

Family

ID=36701685

Family Applications (2)

Application Number Title Priority Date Filing Date
UAA200909651A UA108342C2 (en) 2003-08-18 2004-08-18 METHOD OF PREPARATION OF 4 - ((1R, 3S) -6-CHLORO-3-PHENYLINDAN-1-IL) -1,2,2-TRIMETHYLPIPERASINE OR ITS SALT (OPTIONS), CIS- (1S, 3S) -6-CHLORINE 3-PHENYLINDAN-1-OL, CIS- (1S, 3S) -3-REPLACED-5-CHLORINE-1-PHENYLINDAN AND TRANS-1 - ((1R, 3S) -6-CHLORINE-3-PHENYLINDAN-1-IL ) -3,3-DIMETHYLPIPERASINE
UAA200602709A UA89617C2 (en) 2003-08-18 2004-08-18 Succinate and malonate salt of trans 4-(1r,3s)-6-chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and use thereof as a medicament

Family Applications Before (1)

Application Number Title Priority Date Filing Date
UAA200909651A UA108342C2 (en) 2003-08-18 2004-08-18 METHOD OF PREPARATION OF 4 - ((1R, 3S) -6-CHLORO-3-PHENYLINDAN-1-IL) -1,2,2-TRIMETHYLPIPERASINE OR ITS SALT (OPTIONS), CIS- (1S, 3S) -6-CHLORINE 3-PHENYLINDAN-1-OL, CIS- (1S, 3S) -3-REPLACED-5-CHLORINE-1-PHENYLINDAN AND TRANS-1 - ((1R, 3S) -6-CHLORINE-3-PHENYLINDAN-1-IL ) -3,3-DIMETHYLPIPERASINE

Country Status (4)

Country Link
CN (2) CN1835938A (en)
ME (1) ME00154B (en)
UA (2) UA108342C2 (en)
ZA (2) ZA200601421B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102365265A (en) * 2009-04-09 2012-02-29 欧加农股份有限公司 Indane derivatives
CN103209949B (en) * 2010-11-09 2016-08-10 株式会社钟化 Halogenated indanones and method for producing optically active indanones or optically active indanols using the same
CN103429577A (en) * 2011-01-07 2013-12-04 H.隆德贝克有限公司 Method for resolution of 4-((1R,3S)-6-chloro-3-phenyl-indan-1-yl)-1,2,2-trimethyl-piperazine and 1-((1R,3S)-6-chloro-3-phenyl-indan, 1-yl)-3,3-dimethyl-piperazine
CN112359078A (en) * 2021-01-12 2021-02-12 凯莱英生命科学技术(天津)有限公司 Chiral resolution method of isobutyrate compound

Also Published As

Publication number Publication date
MEP2608A (en) 2010-06-10
UA108342C2 (en) 2015-04-27
ZA200601421B (en) 2007-05-30
CN1839124B (en) 2010-06-16
ME00154B (en) 2010-10-10
ZA200601173B (en) 2007-04-25
CN1835938A (en) 2006-09-20
CN1839124A (en) 2006-09-27

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