UA88448C2 - Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof - Google Patents
Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereofInfo
- Publication number
- UA88448C2 UA88448C2 UAA200600912A UAA200600912A UA88448C2 UA 88448 C2 UA88448 C2 UA 88448C2 UA A200600912 A UAA200600912 A UA A200600912A UA A200600912 A UAA200600912 A UA A200600912A UA 88448 C2 UA88448 C2 UA 88448C2
- Authority
- UA
- Ukraine
- Prior art keywords
- derivatives
- group substituted
- cyclopropyl group
- substituted oxazolidinone
- species
- Prior art date
Links
- IZXIZTKNFFYFOF-UHFFFAOYSA-N 2-Oxazolidone Chemical class O=C1NCCO1 IZXIZTKNFFYFOF-UHFFFAOYSA-N 0.000 title abstract 2
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 title abstract 2
- 239000003242 anti bacterial agent Substances 0.000 title 1
- 229940088710 antibiotic agent Drugs 0.000 title 1
- 241000894007 species Species 0.000 abstract 2
- 241001148536 Bacteroides sp. Species 0.000 abstract 1
- 241001112696 Clostridia Species 0.000 abstract 1
- 241000187479 Mycobacterium tuberculosis Species 0.000 abstract 1
- 241000295644 Staphylococcaceae Species 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 244000052769 pathogen Species 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
This invention relates to new oxazolidinones having a cyclopropyl moiety, which are effective against aerobic and anerobic pathogens such as multi-resistant staphylococci, streptococci and enterococci, Bacteroides spp., Clostridia spp. species, as well as acid-fast organisms such as Mycobacterium tuberculosis and other mycobactenial species. The compounds are represented by structural formula: (I): its enantiomer, diastereomer, or phaimaceutically acceptable salt or ester thereof.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48390403P | 2003-07-02 | 2003-07-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA88448C2 true UA88448C2 (en) | 2009-10-26 |
Family
ID=36908184
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200600912A UA88448C2 (en) | 2003-07-02 | 2004-06-29 | Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof |
Country Status (3)
| Country | Link |
|---|---|
| CN (2) | CN1816545A (en) |
| UA (1) | UA88448C2 (en) |
| ZA (1) | ZA200510432B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12435077B2 (en) | 2020-03-20 | 2025-10-07 | Merck Sharp & Dohme Llc | Oxazolidinone compound and methods of use thereof as an antibacterial agent |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013182070A1 (en) * | 2012-06-08 | 2013-12-12 | 四川贝力克生物技术有限责任公司 | Drug for preventing or treating mycobacterial diseases |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6689779B2 (en) * | 2000-06-05 | 2004-02-10 | Dong A Pharm. Co., Ltd. | Oxazolidinone derivatives and a process for the preparation thereof |
| DE60206154T2 (en) * | 2001-04-17 | 2006-06-29 | Merck & Co., Inc. | BICYCLO [3,1,0] HEXANE AS A STRUCTURAL ELEMENT CONTAINING OXAZOLIDINONE ANTIBIOTICS AND THEIR DERIVATIVES |
| CA2463794A1 (en) * | 2001-11-29 | 2003-06-12 | Merck & Co., Inc. | Cyclopropyl hexane containing oxazolidinone antibiotics and derivatives thereof |
-
2004
- 2004-06-29 UA UAA200600912A patent/UA88448C2/en unknown
- 2004-06-29 CN CN 200480018905 patent/CN1816545A/en active Pending
- 2004-06-29 CN CN200480019102.2A patent/CN1816548B/en not_active Expired - Fee Related
- 2004-06-29 ZA ZA200510432A patent/ZA200510432B/en unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12435077B2 (en) | 2020-03-20 | 2025-10-07 | Merck Sharp & Dohme Llc | Oxazolidinone compound and methods of use thereof as an antibacterial agent |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1816545A (en) | 2006-08-09 |
| CN1816548A (en) | 2006-08-09 |
| ZA200510432B (en) | 2007-03-28 |
| CN1816548B (en) | 2011-01-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MY140137A (en) | Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof | |
| ATE304536T1 (en) | OXAZOLIDINONE ANTIBIOTICS CONTAINING BICYCLO(3,1,0)HEXANE AS A STRUCTURAL ELEMENT AND THEIR DERIVATIVES | |
| MX9703543A (en) | Bicyclic oxazine and thiazine oxazolidinone antibacterials. | |
| MY132698A (en) | Herbicidal composition | |
| NO971946L (en) | Phenyloxazolidinone antimicrobial agents | |
| HUS1500046I1 (en) | Novel oxazolidinone derivatives | |
| MXPA05009205A (en) | Hydroxymethyl substituted dihydroisoxazole derivatives useful as antibiotic agents. | |
| LV12605A (en) | Substituted oxazine and thiazine oxazlidinone antimicrobials | |
| AU6964096A (en) | Aminoaryl oxazolidinone n-oxides | |
| MY161872A (en) | Pyrrolidinyl derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors | |
| EP1409464A4 (en) | Oxazolidinone derivatives as potential antimicrobials | |
| AU7665196A (en) | Oxazolidinone antibacterial agent with tricyclic substituents | |
| EA200500283A1 (en) | OXIAZOLIDINON DERIVATIVES AS ANTI-MICROSAL AGENTS | |
| WO2010058423A3 (en) | Novel antimicrobials | |
| UA88448C2 (en) | Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof | |
| MX9703040A (en) | Phenyloxazolidinone antimicrobials. | |
| TW200600011A (en) | Silylated carboxamides | |
| WO2006018682A3 (en) | Oxazolidinone derivatives as antimicrobials | |
| DOP2004000942A (en) | ANTIBIOTICS OF OXAZOLIDINONA REPLACED WITH A CYCLOPROPILE GROUP AND DERIVATIVES OF THE SAME (CYCLOPROPYL GROUP SUBSTITUED OXAZOLDINONE ANTIBIOTICS AND DERIVATIVES THEREOF) | |
| WO2009116090A3 (en) | Novel antimicrobials |