UA86441C2 - (2-гидроксиэтил)триметиламмония тиоктат (холина тиоктат), имеющий гепатопротекторное, гипоаммониемическое и детоксицирующее действие, способ его получения, фармацевтическая композиция на его основе - Google Patents
(2-гидроксиэтил)триметиламмония тиоктат (холина тиоктат), имеющий гепатопротекторное, гипоаммониемическое и детоксицирующее действие, способ его получения, фармацевтическая композиция на его основеInfo
- Publication number
- UA86441C2 UA86441C2 UAA200703481A UAA200703481A UA86441C2 UA 86441 C2 UA86441 C2 UA 86441C2 UA A200703481 A UAA200703481 A UA A200703481A UA A200703481 A UAA200703481 A UA A200703481A UA 86441 C2 UA86441 C2 UA 86441C2
- Authority
- UA
- Ukraine
- Prior art keywords
- thiooctate
- trimethylammonium
- hydroxyethyl
- hepatoprotective
- hypoamoniemic
- Prior art date
Links
- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 title abstract 8
- 229960001231 choline Drugs 0.000 title abstract 4
- 230000002443 hepatoprotective effect Effects 0.000 title abstract 4
- AGBQKNBQESQNJD-UHFFFAOYSA-M lipoate Chemical compound [O-]C(=O)CCCCC1CCSS1 AGBQKNBQESQNJD-UHFFFAOYSA-M 0.000 title abstract 4
- 229940068511 thioctate Drugs 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
- C07D339/02—Five-membered rings
- C07D339/06—Five-membered rings having the hetero atoms in positions 1 and 3, e.g. cyclic dithiocarbonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
- C07D339/02—Five-membered rings
- C07D339/04—Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| UAA200703481A UA86441C2 (ru) | 2007-03-30 | 2007-03-30 | (2-гидроксиэтил)триметиламмония тиоктат (холина тиоктат), имеющий гепатопротекторное, гипоаммониемическое и детоксицирующее действие, способ его получения, фармацевтическая композиция на его основе |
| PCT/IB2008/000727 WO2008120070A2 (fr) | 2007-03-30 | 2008-03-17 | 2(hydroxyéthyle)triméthylammonium thioctate (choline thioctate) possédant une action hépatoprotectrice, hypoammoniémique et détoxique, procédé de production de cette substance et composition pharmaceutique basée sur ladite substance |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| UAA200703481A UA86441C2 (ru) | 2007-03-30 | 2007-03-30 | (2-гидроксиэтил)триметиламмония тиоктат (холина тиоктат), имеющий гепатопротекторное, гипоаммониемическое и детоксицирующее действие, способ его получения, фармацевтическая композиция на его основе |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA86441C2 true UA86441C2 (ru) | 2009-04-27 |
Family
ID=39808755
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200703481A UA86441C2 (ru) | 2007-03-30 | 2007-03-30 | (2-гидроксиэтил)триметиламмония тиоктат (холина тиоктат), имеющий гепатопротекторное, гипоаммониемическое и детоксицирующее действие, способ его получения, фармацевтическая композиция на его основе |
Country Status (2)
| Country | Link |
|---|---|
| UA (1) | UA86441C2 (fr) |
| WO (1) | WO2008120070A2 (fr) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8697109B2 (en) | 2000-08-16 | 2014-04-15 | Encore Health, Llc | Caged mercaptan and seleno-mercaptan compounds and methods of using them |
| US8647612B2 (en) | 2008-03-05 | 2014-02-11 | Encore Health, Llc | Dithiol compounds, derivatives, and treatment of presbyopia |
| US7914815B2 (en) | 2000-08-16 | 2011-03-29 | Encore Health, Llc | Method for delivery of pharmaceuticals for treating or preventing presbyopia |
| US7935332B2 (en) | 2000-08-16 | 2011-05-03 | Encore Health, Llc | Presbyopia treatment by lens alteration |
| US8147816B2 (en) | 2000-08-16 | 2012-04-03 | Encore Health, Llc | Presbyopia treatment by lens alteration |
| WO2009111635A2 (fr) | 2008-03-05 | 2009-09-11 | Encore Health, Llc | Composés dithiols, dérivés et utilisations associées |
| US9044439B2 (en) | 2008-03-05 | 2015-06-02 | Encore Health, Llc | Low dose lipoic and pharmaceutical compositions and methods |
| EP2442645B1 (fr) * | 2009-06-15 | 2014-08-27 | Encore Health, Llc | Esters de choline |
| DK2442647T3 (en) | 2009-06-15 | 2016-05-30 | Encore Health Llc | Dithiolforbindelser, derivatives thereof, and the uses of these |
| AU2015227307A1 (en) | 2014-03-03 | 2016-10-13 | Encore Vision, Inc. | Lipoic acid choline ester compositions and methods of use |
| MX2020008173A (es) * | 2018-02-05 | 2020-09-25 | Cellix Bio Private Ltd | Combinacion de un agente antimuscarinico o de uno anticolinergico y acido lipoico, y sus usos. |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR4864M (fr) * | 1965-10-21 | 1967-02-27 | ||
| DE19818563C2 (de) * | 1998-04-25 | 2003-04-17 | Sueddeutsche Kalkstickstoff | Verwendung von alpha-Liponsäure zur Verringerung des Appetits und/oder zur Körpergewichtsreduzierung |
-
2007
- 2007-03-30 UA UAA200703481A patent/UA86441C2/ru unknown
-
2008
- 2008-03-17 WO PCT/IB2008/000727 patent/WO2008120070A2/fr not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008120070A2 (fr) | 2008-10-09 |
| WO2008120070A3 (fr) | 2008-12-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| UA86441C2 (ru) | (2-гидроксиэтил)триметиламмония тиоктат (холина тиоктат), имеющий гепатопротекторное, гипоаммониемическое и детоксицирующее действие, способ его получения, фармацевтическая композиция на его основе | |
| MY147994A (en) | Azabiphenylaminobenzoic acid derivatives as dhodh inhibitors | |
| MA33044B1 (fr) | Composition pharmaceutique contenant des derives de glucopyranosyl diphenylmethane, sa forme posologique galenique, son procede de preparation et ses utilisations pour une regulation glycemique amelioree chez un patient | |
| MX2008014101A (es) | Acidos carboxilicos sustituidos con 4,5-difenil-pirimidinilamino, metodo para su produccion y su uso como medicamentos. | |
| UA95644C2 (ru) | Пиридазиноновые производные, фармацевтическая композиция и способ лечения заболеваний | |
| MY183588A (en) | New salvianolic acid compound l, preparation method and use thereof | |
| TN2012000143A1 (en) | Pharmaceutical composition, pharmaceutical dosage form, process for their preparation, methods for treating and uses thereof | |
| MX2011012122A (es) | Derivados de tiofeno. | |
| GEP20135724B (en) | Aminotetrahydropyrans as dipeptidyl peptidase-iv inhibitors for treatment or prevention of diabetes | |
| UA104988C2 (uk) | Похідні піроніндолу та спосіб їх отримання | |
| DE602005021770D1 (de) | Indol-1-yl-essigsäurederivate | |
| WO2008075376A8 (fr) | Formes polymorphes du bortézomibe et leur procédé de préparation | |
| MX2010009022A (es) | Derivados 16 alfa, 17 alfa-acetal glucocorticoesteroideos y su uso. | |
| ATE513820T1 (de) | Neue benzamidinderivate, verfahren zu deren herstellung und pharmazeutische zusammensetzung, die diese enthält | |
| JO2673B1 (en) | Diosmetin compounds, method of preparation and pharmaceutical compositions | |
| WO2010090494A3 (fr) | Utilisation médicale de dérivés d'acide 5-benzylaminosalicylique ou de sels correspondants | |
| TW200505880A (en) | Diarylcycloalkyl derivatives, process for their preparation and their use as pharmaceuticals | |
| UA96794C2 (ru) | Глюкокортикоиды, способ их применения, способ лечения и фармацевтическая композиция на их основе | |
| UA97122C2 (ru) | Кристаллическая форма миндальной кислоты как ингибитор тромбина (варианты) | |
| IN2011KN05169A (fr) | ||
| GB2446341A (en) | Method and system for transdermal drug delivery | |
| TW200635916A (en) | Compounds | |
| TW200726758A (en) | New pyridine analogues | |
| MY146802A (en) | Novel drugs for treating respiratory diseases | |
| MY179041A (en) | Crystalline forms of a 3-carboxypropyl-aminotetralin compound |