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UA8031A1 - Process for preparing 2-bromo-alpha-ergocryptine - Google Patents

Process for preparing 2-bromo-alpha-ergocryptine

Info

Publication number
UA8031A1
UA8031A1 UA2553348A UA2553348A UA8031A1 UA 8031 A1 UA8031 A1 UA 8031A1 UA 2553348 A UA2553348 A UA 2553348A UA 2553348 A UA2553348 A UA 2553348A UA 8031 A1 UA8031 A1 UA 8031A1
Authority
UA
Ukraine
Prior art keywords
ergocryptine
alpha
bromo
preparing
bromosaccharin
Prior art date
Application number
UA2553348A
Other languages
Russian (ru)
Ukrainian (uk)
Inventor
Ручман Рудольф
Коршич Яня
Котар Мілена
Котар Милена
Original Assignee
"Сандос АГ"
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by "Сандос АГ" filed Critical "Сандос АГ"
Publication of UA8031A1 publication Critical patent/UA8031A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/02Ergot alkaloids of the cyclic peptide type

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

A process for the preparation of a 2-bromo-alpha-ergocryptine is characterised in that alpha-ergocryptine in an inert atmosphere is brominated with pyrrolidinone hydrotribromide or N-bromosaccharin in solution in cyclic ether in the presence of 2,2'-azobis-(2-methyl propane nitrile) as radical initiator at room temperature.
UA2553348A 1976-12-23 1977-12-13 Process for preparing 2-bromo-alpha-ergocryptine UA8031A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
YU3134/76A YU39786B (en) 1976-12-23 1976-12-23 Process for preparing 2-bromo-alfa-ergocriptine

Publications (1)

Publication Number Publication Date
UA8031A1 true UA8031A1 (en) 1995-12-26

Family

ID=25559398

Family Applications (1)

Application Number Title Priority Date Filing Date
UA2553348A UA8031A1 (en) 1976-12-23 1977-12-13 Process for preparing 2-bromo-alpha-ergocryptine

Country Status (18)

Country Link
JP (1) JPS5384997A (en)
BE (1) BE903269Q (en)
CS (1) CS215105B2 (en)
DD (1) DD134101A1 (en)
DE (1) DE2752532C3 (en)
ES (1) ES465096A1 (en)
FR (1) FR2375242A1 (en)
GB (1) GB1574479A (en)
HK (1) HK4786A (en)
HU (1) HU176817B (en)
KE (1) KE3572A (en)
PL (1) PL106363B1 (en)
PT (1) PT67340A (en)
RO (1) RO71277A (en)
SG (1) SG71885G (en)
SU (1) SU795477A3 (en)
UA (1) UA8031A1 (en)
YU (1) YU39786B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU216177A (en) 1977-09-09 1984-02-29 Rudolf Rucman Process for preparing 2-bromo ergosine
YU39849B (en) * 1978-09-26 1985-04-30 Lek Tovarna Farmacevtskih Process for preparing 2-bromo-ergolene and 2-bromo-ergoline compounds
RU2274640C1 (en) * 2004-09-15 2006-04-20 Всероссийский научно-исследовательский институт лекарственных и ароматических растений ("ВИЛАР") METHOD FOR BROMINATION OF α- AND β-ERGOCRYPTINES

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH507249A (en) * 1968-05-31 1971-05-15 Sandoz Ag Process for the preparation of 2-bromo-a-ergocryptine
YU216177A (en) * 1977-09-09 1984-02-29 Rudolf Rucman Process for preparing 2-bromo ergosine

Also Published As

Publication number Publication date
DE2752532C3 (en) 1980-09-18
PL202697A1 (en) 1978-07-31
DD134101A1 (en) 1979-02-07
FR2375242B1 (en) 1983-01-14
FR2375242A1 (en) 1978-07-21
KE3572A (en) 1985-11-08
SU795477A3 (en) 1981-01-07
PL106363B1 (en) 1979-12-31
CS215105B2 (en) 1982-07-30
YU313476A (en) 1982-05-31
HU176817B (en) 1981-05-28
ES465096A1 (en) 1978-09-01
YU39786B (en) 1985-04-30
HK4786A (en) 1986-01-31
PT67340A (en) 1977-12-01
DE2752532A1 (en) 1978-06-29
RO71277A (en) 1982-02-01
DE2752532B2 (en) 1979-12-06
GB1574479A (en) 1980-09-10
BE903269Q (en) 1986-01-16
SG71885G (en) 1988-09-30
JPS5384997A (en) 1978-07-26
JPS5550038B2 (en) 1980-12-16

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