UA50266U - PROCESS FOR THE PREPARATION OF SUBSTITUTED 7-HYDROXY-7-METHYL-2-(ALKYLTHIO)-N,5-DIARYL-4,5,6,7-TETRAHYDRO[1,2,4]TRIAZOLO[1,5-α]PYRIMIDIN-6-CARBOXAMIDES - Google Patents
PROCESS FOR THE PREPARATION OF SUBSTITUTED 7-HYDROXY-7-METHYL-2-(ALKYLTHIO)-N,5-DIARYL-4,5,6,7-TETRAHYDRO[1,2,4]TRIAZOLO[1,5-α]PYRIMIDIN-6-CARBOXAMIDESInfo
- Publication number
- UA50266U UA50266U UAU201000009U UAU201000009U UA50266U UA 50266 U UA50266 U UA 50266U UA U201000009 U UAU201000009 U UA U201000009U UA U201000009 U UAU201000009 U UA U201000009U UA 50266 U UA50266 U UA 50266U
- Authority
- UA
- Ukraine
- Prior art keywords
- alkylthio
- substituted
- carboxamides
- triazolo
- diaryl
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- -1 dicarbonyl compound Chemical class 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- WDJHALXBUFZDSR-UHFFFAOYSA-N acetoacetic acid Chemical compound CC(=O)CC(O)=O WDJHALXBUFZDSR-UHFFFAOYSA-N 0.000 abstract 1
- 229940051881 anilide analgesics and antipyretics Drugs 0.000 abstract 1
- 150000003931 anilides Chemical class 0.000 abstract 1
- 150000003934 aromatic aldehydes Chemical class 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 238000006482 condensation reaction Methods 0.000 abstract 1
- 235000019441 ethanol Nutrition 0.000 abstract 1
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
A process for the preparation of substituted 7-hydroxy-7-methyl-2-(alkylthio)-N,5-diaryl-4,5,6,7-tetrahydro[1,2,4]triazolo[1,5-α]pyrimidin-6-carboxamides involves condensation of equimolar amounts of dicarbonyl compound, aromatic aldehyde and 3-alkylthio-5-amino-1H-1,2,4-triazole in solvent. Diacetic acid aryl-substituted anilides of formula CHCOCHCONHAr are used as dicarbonyl compound, ethyl alcohol is used as solvent, and condensation reaction is carried out at a temperature of 18-25 °C for 20-40 minutes up to formation of the desired product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| UAU201000009U UA50266U (en) | 2010-01-11 | 2010-01-11 | PROCESS FOR THE PREPARATION OF SUBSTITUTED 7-HYDROXY-7-METHYL-2-(ALKYLTHIO)-N,5-DIARYL-4,5,6,7-TETRAHYDRO[1,2,4]TRIAZOLO[1,5-α]PYRIMIDIN-6-CARBOXAMIDES |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| UAU201000009U UA50266U (en) | 2010-01-11 | 2010-01-11 | PROCESS FOR THE PREPARATION OF SUBSTITUTED 7-HYDROXY-7-METHYL-2-(ALKYLTHIO)-N,5-DIARYL-4,5,6,7-TETRAHYDRO[1,2,4]TRIAZOLO[1,5-α]PYRIMIDIN-6-CARBOXAMIDES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA50266U true UA50266U (en) | 2010-05-25 |
Family
ID=50689640
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAU201000009U UA50266U (en) | 2010-01-11 | 2010-01-11 | PROCESS FOR THE PREPARATION OF SUBSTITUTED 7-HYDROXY-7-METHYL-2-(ALKYLTHIO)-N,5-DIARYL-4,5,6,7-TETRAHYDRO[1,2,4]TRIAZOLO[1,5-α]PYRIMIDIN-6-CARBOXAMIDES |
Country Status (1)
| Country | Link |
|---|---|
| UA (1) | UA50266U (en) |
-
2010
- 2010-01-11 UA UAU201000009U patent/UA50266U/en unknown
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