UA43574U - Composition for treating generalized periodontitis - Google Patents

Abstract

A composition for treating the generalized periodontitis contains sodium diclofenac, chlorohexidine bigluconate, and enterosgel.

Description

(51) IPC (2009)

CC AbIK 33/20

M

MINISTRY OF EDUCATION and

SCIENCES OF UKRAINE (F) P I S is published under

RESPONSIBILITY

STATE DEPARTMENT pase

INTELLECTUAL to PATENT PATENT

PROPERTIES FOR A USEFUL MODEL soooo! ИІОГЩНИАЛТТЬООЬТТООООООООООТЬТИТИТИТИТИТИТИТИТИТИТЬТЬТЬТЬТЬТЬТЬТЬТЬТЬТЬТЬТЬНИЬТНЬНЬНЬТНЬНЬЬЬИЬИЬЬЙЬЬИКИЬКИЬЬКЬЬКЬЩНЬКЬІХКХКХИХЬХКХКХИХХХККНКИИОХТИНТТЬТЬТЬТНИИХИХИТЬТЬТНТЬТЬТНХШХШИХШИТИНЕИНЬ У ШИЛІИІИПБІІЮЯВОСТИТЯХТИТТНТИИТИТИТИТТЬТИТИТИНТИТНИТИТЬИТИНИТИТИНИИТИИИНННИЯ (54) СКЛАД ДЛЯ ЛІКУВАННЯ ГЕНЕРАЛІЗОВАНОГО ПАРОДОНТИТУ 1 2 (21) и200902117 (57) Склад для лікування генералізованого паро- (22) 11.03.2009 донтиту, що містить диклофенак натрію, який від- (24) 25.08.2009 різняється тим , which additionally contains chlorhexi- (46) 08.25.2009, Byul. Mo 16, 2009 dino bigluconate and enterosgel with the following (72) YAROVA SVITLANA PAVLIVNA, SANOYAN VIK- ratios of components, wt. 9 o'clock:

TORIA VOLODYMIRIVNA sodium diclofenac 25.0 (73) DONTSKY NATIONAL MEDICAL chlorhexidine bigluconate 25.0

THE UNIVERSITY M. GORKOYO enterosgel 50.0.

A useful model relates to medicine, with a closed effect, has sorption properties and specifics of dentistry, and can be used for local drug therapy in patients with generalized periodontitis. nom periodontitis. The set task is solved by the fact that

The well-known composition of dental films for the honey composition for the treatment of generalized topical drug treatment in chronic periodontitis, in addition to diclofenac sodium, in addition to generalized periodontitis, we have chosen chlorhexidine billuconate and enterosgel as a prototype |1), includes sodium diclofenac, acid in the following ratios of components, mass 9Uo: ascorbic acid, sodium carboxymethylcellulose, sodium diclofenac - 25.0; chlorhexidine biglucose with glycerin, dimexide, polyethylene oxide-400, nipagin, nat - 25.0; enterosgel - 50.0. nipazole and sodium saccharin. The composition in the form of a film The composition is prepared as follows: 1 tablet - apply to the gums and mucous membrane of the oral diclofenac sodium, rub it into a powder-like cavity after thorough sanitation of the cavity of the working mass, dissolve in 10 drops of 0.295 solution and (elimination of traumatic nodes, careful appearance - chlorhexidine bigluconate, then the obtained mixture is immobilized under irrigation of the gums on enterosgel, the ingredients of the mixture - "And with solutions of antiseptics, periodontal curettage in the ratio of components 1:1:2. Data from regional pockets). boats were chosen for a number of them. features and IR

However, this composition for local medicinal benefits, namely: of the known antiseptic preparations for the treatment of generalized periodontitis, chlorhexidine bigluconate is the most effective. This agent is difficult to apply in relation to the periodontal microflora in the form of a biopolymer film. It has been established that it has a quick and persistent antimicrobial effect even in patients with generalized periodontitis. Diclofenac sodium has anti-

of severity, elimination of inflammatory phenomena in inflammatory, analgesic, anti-radical and anti- periodontal tissues is observed only in acidifying effect, is one of the safest non- " 88,496 patients. At the same time, after 6-8 months in steroid anti-inflammatory drugs. Immobilization of them causes a relapse of the disease with a characteristic clinical picture of enterosgel. These facts make the application of the ecological effect of the components, and the enterosgel itself, which is of a given composition for the local medicinal topic, has selective sorption properties, allows the therapy to be ineffective. remove from the pathological center in the tissues of the

The basis of a useful model is the task of rodent microorganisms, their toxins and decomposition products for the treatment of generalized tissue decline. It is able to easily disperse in periodontitis, which will increase the effectiveness of the drug and mix with it in almost any treatment and shorten the time of local treatment. highly effective drugs due to the increase in the surface of contact with mucous substances that have a pronounced anti-inflammatory membrane. The composition for the treatment of general

Claims (1)

periodontitis is used the next day the gums correspond to the concept of "healthy". Due to the method: thorough sanitation of the cavity is carried out, no relapses of the disease were noted for months. mouth in patients with generalized periodontitis: Approbation of the composition was carried out in the 31st patient for the removal of soft plaque, supra- and sub-generalized periodontitis I, PP and Ж degree of gingival dental deposits, caries filling. The proposed composition for the treatment of cavities, selective grinding of the teeth of generalized periodontitis due to the fact that under the irrigation of solutions of antiseptics. After the san- it includes anti-inflammatory (diclofenac oral cavity conduct a course of local me- sodium), antiseptic (chlorhexidine biglucanate) dicamentous treatment of generalized steam preparations, make a complex anti-inflammatory, periodontal: instillation into the periodontal pocket analgesic and directed effect on the aggressively proposed paste on the gums for 1 hour, active pathogenic microflora in patients with gener- every day until the signs of inflammation of the gums with ralized periodontitis completely disappear. Due to such a sub- (within 5-8 days). course, a stable clinical effect is achieved, we give specific examples of use, the effectiveness of the treatment is increased and the proposed composition is reduced. terms of local medical treatment Example 1. Patient C, 32 years old. Diagnosis: chronic generalized periodontitis. The results showed that the generalized periodontitis of the III degree was severe, and the use of the composition allows for 10-15905 cents. Complex anti-inflammatory therapy was carried out to increase the effectiveness of generalized treatment and curettage of periodontal pockets, cleaning of teeth and periodontitis and to shorten the treatment period by 1-3 from mild plaque; removal of over- and under-visits in patients. Obtained results, gingival dental deposits; removal of the content of par- approbation of the claimed composition, confirmation of periodontal pockets, filling of carious cavities, its high effectiveness for local cavities, removal of nodes of traumatic occlusion, cementotic treatment of generalized periodontal splinting of teeth. For local medicinal ntitis in patients. therapy used a composition containing a solution Sources of information taken into account: sodium diclofenac and chlorhexidine bigluconate, 1. Korytniuk R.S., Melnyk M.O., Davtyan L.L. immobilized on enterogel in ratios, etc. Development of the composition of dental films from components 1:1:2; in the form of installations in the periodontium - sodium diclofenac // Herald of pharmacy. - 2002. - thermal pockets for 1 hour, once per do- Mo2 (30). - P.70. before the disappearance of signs of inflammation in the gums. On the 8th Computer layout by L. Kupenko Signature Circulation 28 approx. Ministry of Education and Science of Ukraine State Department of Intellectual Property, str. Urytskogo, 45, m. Kyiv, MSP, 03680, Ukraine SE "Ukrainian Institute of Industrial Property", str. Glazunova, 1, m. Kyiv - 42, 01601