UA160823U - Method for producing carbon enterosorbents - Google Patents

Description

The utility model belongs to the medical industry, in particular to the production of carbon sorption materials (enterosorbents), which are used orally in acute and chronic poisonings, endogenous intoxications, acute intestinal and some immunodependent diseases.

The closest analogue is the method of obtaining carbon enterosorbents (Ukrainian patent for invention No. ША 62849). According to this method, activated materials are crushed, moistened to a residual moisture content of 30-70% by weight relative to the dry mass of the sorbent, and then granules are formed by mixing, sieving or rubbing through a perforated plate or a punching sieve, or by using a special granulator.

The disadvantage of the method of obtaining carbon enterosorbents is that during packaging, storage and transportation of granules, their partial destruction or shedding with the formation of small fragments of the sorbent is possible due to the loss (evaporation) of moisture from the surface of the granules, or from their internal and intergranular space, which is associated with small forces of interaction between water and the sorption material itself. Another disadvantage is that under the conditions of the formation of condensate droplets and their seepage into the upper and lower layers of the granulated carbon enterosorbent packaged in special containers, partial adhesion of the granules with the formation of large conglomerates is possible.

The utility model is based on the task of improving the method of obtaining a carbon enterosorbent, consisting of the sorbent itself and water, by improving its mechanical properties, which allows obtaining a stable form of the drug that does not change during storage, as well as under mechanical loads accompanying its packaging, transportation and use.

The problem is solved by the fact that the method for producing carbon enterosorbents includes the technological stages of grinding activated carbon materials to obtain a fraction of particles with sizes from 1 to 150 microns, drying them at a temperature of 220-230 "C to a constant dry mass, moistening to a residual moisture content in the finished preparation of 30-70 95 relative to the dry mass of the sorbent, forming granules using a special granulator and rolling them in a dry powder of crushed activated carbon material for 30 minutes.

The granules treated in this way are packed in a sealed container and are easily dosed with a conventional dosing device. The granulometric composition of the resulting mixture does not change under mechanical influences, vibration, transport shaking, etc. Wet granules rolled in dry powder of crushed activated material do not collapse (do not crumble) due to the absence of moisture loss and do not stick together due to the absence of condensate formation.

Wet granules obtained by the claimed method fully retain the advantages of water-carbon mixtures, which consist in the absence of the effect of pore screening by the binder, as well as in the improvement of sorption kinetics due to the preliminary filling of the transport pores with water, as well as in the high organoleptic properties of the drug, which allow it to be swallowed with a minimum amount of water in the form of an indifferent mushy substance.

The method is carried out as follows.

A given amount of activated carbon material is ground by extrusion or in a ball mill to obtain particles from 1 to 150 microns, dried at a temperature of 220-230 "C to a constant dry mass, moistened with water to a residual moisture content in the finished preparation of 30-70 95 relative to the dry mass of the sorbent, granulated using a granulator, and rolled in a dry powder of crushed activated carbon material for 30 minutes.

The quality of the granules is assessed by the criteria of their absence of clumping into large conglomerates, which are formed with an excess of water, or their scattering into powder with an insufficient amount of water. Table 1 shows the limiting comparative values of residual moisture (90) in granules obtained by various methods using crushed activated carbon of the AUT-M brand, which ensure a stable shape of the granules.

Table 1

Limit values of residual moisture (95) in the finished granulate made from crushed activated carbon of the AUT-M brand, which ensures the preservation of a stable shape of the granules

Method for obtaining analog granulate

The comparative data presented in Table 1 on the limit values of residual moisture (90) for ensuring and maintaining a stable shape of the finished granulate demonstrate the difference in the moisture range of granules obtained by the claimed method and the method described in the analogue.

Table 2 presents comparative results of testing the strength of wet granules made from crushed activated carbon of the AUT-M brand, obtained by the proposed method and by the method presented in the analogue, after standard vibration loading.

Table 2

Mass 95 of carbon material passing through standard sieves before and after mechanical loading

Method of obtaining granulate standard sieves

The data presented in Table 2 clearly demonstrate the reduction in the amount of carbon material passing through the sieves in the proposed method. After the same mechanical load, wet granules rolled in dry powder of crushed activated carbon material, obtained by the proposed method, are less destroyed, i.e. the amount of sieved material before and after mechanical load does not change significantly. | Although the changes in the sieved material are not significant in both methods being compared, the result presented in Table 2 demonstrates a higher mechanical stability of enterosorbents in the form of wet granules obtained by the new claimed method, in comparison with that of wet granules obtained by the proposed method.

A method for producing a carbon enterosorbent, in which activated materials are crushed, moistened with water to a residual moisture content in the finished preparation of 30-70% by weight relative to the dry mass of the sorbent, and formed into granules using a special granulator.

The activated carbon material is ground to obtain a particle fraction with sizes from 1 to 150 microns; before moistening, the ground carbon material is dried at a temperature of 220-230 °C to a constant dry mass.

The granules obtained after the granulator are rolled in dry powder of crushed activated carbon material for 30 minutes.

Claims (1)

A method for producing a carbon enterosorbent, in which the activated materials are crushed, moistened with water to a residual moisture content in the finished preparation of 30-70% by weight relative to the dry mass of the sorbent, formed into granules using a special granulator, which is characterized in that the activated carbon material is crushed to obtain a particle fraction with sizes from 1 to 150 microns, before moistening the crushed carbon material is dried at a temperature of 220-230 ° C to a constant dry mass, and the granules obtained after the granulator are rolled in a dry powder of crushed activated carbon material for 30 minutes.